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United States Department of Agriculture

Agricultural Research Service

Bacterial Toxins
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Project 5325-42000-048-00D: Technologies for Detecting and Determining the Bioavailability of Bacterial Toxins

Emphasizing methods that can be used to solve practical problems facing the food industry and regulatory agencies, this project develops reagents and techniques for established as well as emerging assay platforms. Our approaches include immunochemical and activity-based assays. Bacterial toxins (such as botulinum neurotoxins, Shiga toxins, and staphylococcal enterotoxins) and their variants are characterized using these detection systems. New in vitro methodology is calibrated against animal bioassays, and the impact of food processing on toxin activity and bioavailability is determined. The availability of new antibodies and assays will enhance our nation’s capability to monitor for toxins in food, providing enhanced food safety and biosecurity.

Scientists review results of immunoassay. ARS photo K11635-1  Project team:
Two Project scientists review results of a rapid immunoassay (Larry Stanker, standing, and David Brandon). Image Number K11635-1, ARS Information Staff.


Last Modified: 4/8/2014
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