Projects

Genomic and Immunological Characteristics of Johne's Disease Appropriated (D)   Accession Number: 411740

Antigens of Mycobacterium Avium Subsp. Paratuberculosis Reimbursable (R)   Accession Number: 418307

Publications

mosR, A Novel Transcriptional Regulator of Hypoxia and Virulence in Mycobacterium tuberculosis - (Peer Reviewed Journal)

Abomoelak, B., Chi, J., Hoye, E.A., Bannantine, J.P., Talaat, A.M. 2009. MosR, A Novel Transcriptional Regulator of Hypoxia and Virulence in Mycobacterium tuberculosis. Journal of Bacteriology [e-pub ahead of print]. Available: http://jb.asm.org/cgi/reprint/JB.00778-09v1?view=long&pmid=19648248

Isolation of Mycobacterium avium subspecies paratuberculosis Reactive T-cells from Intestinal Biopsies of Crohn's Disease Patients - (Peer Reviewed Journal)

Olsen, I., Tollefsen, S., Aagaard, C., Reitan, L.J., Bannantine, J.P., Sollid, L.M., Lundin, K.E. 2009. Isolation of Mycobacterium avium Subspecies paratuberculosis Reactive CD4 T Cells from Intestinal Biopsies of Crohn's Disease Patients. PLoS One [serial online]. 4(5):e5641. Available: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0005641.

A Novel Cell Wall Lipopeptide Is Important for Biofilm Formation and Pathogenicity of Mycobacterium avium subspecies paratuberculosis - (Peer Reviewed Journal)

Wu, C., Schmoller, S.K., Bannantine, J.P., Eckstein, T.M., Inamine, J.M., Livesey, M., Albrecht, R., Talaat, A. 2009. A Novel Cell Wall Lipopeptide Is Important for Biofilm Formation and Pathogenicity of Mycobacterium avium subspecies paratuberculosis. Microbial Pathogenesis. 46(4):222-230.

Mycobacterium avium subspecies paratuberculosis - (Book/Chapter)

Li, L., Singh, S., Bannantine, J.P., Kanjilal, S., Kapur, V. 2009. Mycobacterium avium subspecies paratuberculosis. In: Nene, V., Kole, C., editors. Genome Mapping and Genomics in Animal-Associated Microbes. Berlin/Heidelberg, Germany: Springer-Verlag. p. 65-83.

Immunogenicity of Proteome-determined Mycobacterium avium subsp. paratuberculosis-specific Proteins in Sheep with Paratuberculosis - (Peer Reviewed Journal)

Hughes, V., Bannantine, J.P., Denham, S., Smith, S., Garcia-Sanchez, A., Sales, J., Paustian, M., Mclean, K., Stevenson, K. 2008. Immunogenicity of Proteome-determined Mycobacterium avium subsp. paratuberculosis-specific Proteins in Sheep with Paratuberculosis. Clinical and Vaccine Immunology. 15(12):1824-1833.

Proteomic Comparison of the Cattle and Sheep Strains of Mycobacterium avium subsp. paratuberculosis in Different Growth Conditions Using iTRAQ Analysis - (Abstract)

Senthilkumar, T.M., Janagama, H.K., Paustian, M., Bannantine, J.P., Sreevatsan, S. 2008. Proteomic Comparison of the Cattle and Sheep Strains of Mycobacterium avium subsp. paratuberculosis in Different Growth Conditions Using iTRAQ Analysis [abstract]. Johne's Disease Integrated Program. p. 29.

Immunization with a DNA Vaccine Cocktail Induces a Th1 Response and Protects Mice Against Mycobacterium avium subsp. paratuberculosis Challenge - (Peer Reviewed Journal)

Park, S., Kathaperumal, K., Mcdonough, S.P., Akey, B., Huntley, J., Bannantine, J.P., Chang, Y. 2008. Immunization with a DNA Vaccine Cocktail Induces a Th1 Response and Protects Mice Against Mycobacterium avium subsp. paratuberculosis Challenge. Vaccine. 26(34):4329-4337.

Gene Regulatory Networks Activated during Chronic Tuberculosis - (Abstract)

Abomoelak, B., Chi, J., Bannantine, J.P., Talaat, A.M. 2008. Gene Regulatory Networks Activated during Chronic Tuberculosis [abstract]. American Society for Microbiology 108th General Meeting. Poster No. U-056.

Rapid Label Free Sero-diagnosis of Johne's Disease Using Surface Plasmon Resonance Biosensor - (Abstract)

Jagadeesan, B., Raizman, E., Nanduri, V., Bannantine, J.P., Bhunia, A.K. 2008. Rapid Label Free Sero-diagnosis of Johne's Disease Using Surface Plasmon Resonance Biosensor [abstract]. American Society for Microbiology. p. 247.

Functional Characterization of Iron Dependent Regulator (IdeR) of Mycobacterium avium subsp. paratuberculosis - (Abstract)

Janagama, H.K., Bannantine, J.P., Kumas T.M.A., S., Rodriguez, G.M., Smith, I., Sreevatsan, S. 2008. Functional Characterization of Iron Dependent Regulator (IdeR) of Mycobacterium avium subsp. paratuberculosis [abstract]. Johne's Disease Integrated Program. p. 31

Detection of Mycobacterium avium subsp. paratuberculosis by a Heterogeneous Surface-Enhanced Raman Scattering Immunoassay - (Abstract)

Yakes, B.J., Lipert, R.J., Bannantine, J.P., Porter, M.D. 2008. Detection of Mycobacterium avium subsp. paratuberculosis by a Heterogeneous Surface-Enhanced Raman Scattering Immunoassay [abstract]. Johne's Disease Integrated Program. p. 21.

Rapid Label Free Sero-Diagnosis of Johne's Disease Using Surface Plasmon Resonance Biosensor - (Abstract)

Jagadeesan, B., Raizman, E., Nanduri, V., Bannantine, J.P., Bhunia, A.K. 2008. Rapid Label Free Sero-Diagnosis of Johne's Disease Using Surface Plasmon Resonance Biosensor [abstract]. Johne's Disease Integrated Program. p. 22.

Development and Evaluation of a Variable-number Tandem Repeat (VNTR) Method for Subtyping of Mycobacterium avium subspecies paratuberculosis Isolates - (Abstract)

Li, L., Amonsin, A., Sreevatsan, S., Bannantine, J.P., Sevilla, I., Juste, R., Kapur, V. 2008. Development and Evaluation of a Variable-number Tandem Repeat (VNTR) Method for Subtyping of Mycobacterium avium subspecies paratuberculosis Isolates [abstract]. Johne's Disease Integrated Program. p. 30.

Vaccination with rMAP Proteins Induces Protection in a Goat Model Against Infection by Oral Challenge - (Abstract)

Chen, J., Kathaperumal, K., Mcdonough, S., Akey, B., Huntley, J., Bannantine, J.P., Chang, Y. 2008. Vaccination with rMAP Proteins Induces Protection in a Goat Model Against Infection by Oral Challenge [abstract]. Johne's Disease Integrated Program. p. 16.

Roles of MAP1152 and MAP1156 Proteins in the Immunopathogenesis of Mycobacterium paratuberculosis - (Abstract)

Barletta, R.G., Chacon, O., Fenton, R.J., Zinniel, D.K., Paulson, A.L., Kuszak, J.A., Mcvey, D.S., Smith, D.R., Bannantine, J.P. 2008. Roles of MAP1152 and MAP1156 Proteins in the Immunopathogenesis of Mycobacterium paratuberculosis [abstract]. Johne's Disease Integrated Program. p. 12.

Osteopontin: A Novel Cytokine Involved in the Regulation of Mycobacterium avium subsp. paratuberculosis Infection in Periparturient Dairy Cattle - (Peer Reviewed Journal)

Karcher, E.L., Bayles, D.O., Bannantine, J.P., Beitz, D.C., Stabel, J.R. 2008. Osteopontin: A Novel Cytokine Involved in the Regulation of Mycobacterium avium subsp. paratuberculosis Infection in Periparturient Dairy Cattle. Journal of Dairy Science. 91(8):3079-3091.

Comparative Genomic Analysis of Mycobacterium avium subspecies Obtained from Multiple Host Species - (Peer Reviewed Journal)

Paustian, M., Zhu, X., Sreevatsan, S., Robbe-Austerman, S., Kapur, V., Bannantine, J.P. 2008. Comparative Genomic Analysis of Mycobacterium avium subspecies Obtained from Multiple Host Species. Biomed Central (BMC) Genomics. 9:135. Available: http://www.biomedcentral.com/1471-2164/9/135.

Early Antibody Response Against Mycobacterium avium subspecies paratuberculosis Antigens in Subclinical Cattle - (Peer Reviewed Journal)

Bannantine, J.P., Bayles, D.O., Waters, W.R., Palmer, M.V., Stabel, J.R., Paustian, M. 2008. Early Antibody Response Against Mycobacterium avium subspecies paratuberculosis Antigens in Subclinical Cattle. Proteome Science. 6:5.

Osteopontin Immunoreactivity in Peripheral Blood Mononuclear Cells, Ileum, and Ileocecal Lymph Node of Dairy Cows Naturally Infected with Mycobacterium avium subsp. paratuberculosis - (Abstract)

Karcher, E.L., Johnson, C.S., Bannantine, J.P., Beitz, D.C., Stabel, J.R. 2008. Osteopontin Immunoreactivity in Peripheral Blood Mononuclear Cells, Ileum, and Ileocecal Lymph Node of Dairy Cows Naturally Infected with Mycobacterium avium subsp. paratuberculosis [abstract]. American Dairy Science Association.

Demonstration of Allelic Exchange in the Slow-Growing Bacterium Mycobacterium avium subsp. paratuberculosis, and Generation of Mutants with Deletions at the pknG, relA and lsr2 Loci - (Peer Reviewed Journal)

Park, K.T., Dahl, J.L., Bannantine, J.P., Barletta, R.G., Ahn, J., Allen, A.J., Hamilton, M.J., Davis, W.C. 2008. Demonstration of Allelic Exchange in the Slow-Growing Bacterium Mycobacterium avium subsp. paratuberculosis, and Generation of Mutants with Deletions at the pknG, relA and lsr2 Loci. Applied and Environmental Microbiology. 74(6):1687-1695.

Immune Responses in Mice to Mycobacterium avium subsp. paratuberculosis Following Vaccination with a Novel 74F Recombinant Polyprotein - (Peer Reviewed Journal)

Chen, L., Kathaperumal, K., Huang, C., Mcdonough, S.P., Stehman, S., Akey, B., Huntley, J., Bannantine, J.P., Chang, C., Chang, Y. 2008. Immune Responses in Mice to Mycobacterium avium subsp. paratuberculosis Following Vaccination with a Novel 74F Recombinant Polyprotein. Vaccine. 26(9):1253-1262.

Profiling Host Antibody Responses to Mycobacterium avium subspecies paratuberculosis Infection Using Protein Arrays - (Peer Reviewed Journal)

Bannantine, J.P., Paustian, M., Waters, W.R., Stabel, J.R., Palmer, M.V., Li, L., Kapur, V. 2007. Profiling Host Antibody Responses to Mycobacterium avium subspecies paratuberculosis Infection Using Protein Arrays. Infection and Immunity. 76(2):739-749.

Detection of Mycobacterium avium subsp. paratuberculosis by a Sonicate Immunoassay Based on Surface-Enhanced Raman Scattering - (Peer Reviewed Journal)

Yakes, B.J., Lipert, R.J., Bannantine, J.P., Porter, M.D. 2008. Detection of Mycobacterium avium subsp. paratuberculosis by a Sonicate Immunoassay Based on Surface-Enhanced Raman Scattering. Clinical and Vaccine Immunology. 15(2):227-234.

Draft Genome Sequence of an Ovine Mycobacterium avium subspecies paratuberculosis Isolate - (Abstract)

Paustian, M., Kapur, V., Sreevatsan, S., Bannantine, J.P. 2007. Draft Genome Sequence of an Ovine Mycobacterium avium subspecies paratuberculosis Isolate [abstract]. Abstract No. 104C-05. p. 61.

Development and Characterization of attenuated Mutant Candidate Vaccines for Control of Paratuberculosis - (Abstract)

Park, K.T., Dahl, J.L., Bannantine, J.P., Barletta, R.G., Allen, A.J., Hamilton, M.J., Park, M.K., Davis, W.C. 2007. Development and Characterization of attenuated Mutant Candidate Vaccines for Control of Paratuberculosis [abstract]. 9th International Colloquium on Paratuberculosis. Abstract No. 20A, p. 106.

Antigenic Profiles of Recombinant Proteins from Mycobacterium avium subsp paratuberculosis in Sheep with Johne's Disease - (Peer Reviewed Journal)

Bannantine, J.P., Rosu, V., Zanetti, S., Rocca, S., Ahmed, N., Sechi, L.A. 2008. Antigenic Profiles of Recombinant Proteins from Mycobacterium avium subsp. paratuberculosis in Sheep with Johne's Disease. Veterinary Immunology and Immunopathology. 122(1-2):116-125.

Development and Use of a Partial Mycobacterium avium subspecies paratuberculosis Protein Array - (Peer Reviewed Journal)

Bannantine, J.P., Waters, W.R., Stabel, J.R., Palmer, M.V., Li, L., Kapur, V., Paustian, M. 2008. Development and Use of a Partial Mycobacterium avium subspecies paratuberculosis Protein Array. Proteomics. 8(3):463-474.

Macrophage Transcriptional Response to Species-Adapted Mycobacterium avium subsp. Paratuberculosis Isolates: The Role of Pathogen Genotype in Host Response - (Abstract)

Paustian, M., Janagama, H.K., Motiwala, A.S., Sreevatsan, S., Bannantine, J.P. 2007. Macrophage Transcriptional Response to Species-Adapted Mycobacterium avium subsp. Paratuberculosis Isolates: The Role of Pathogen Genotype in Host Response [abstract]. Abstract No. PA-072. p. 59.

Identification and Characterization of Iron Dependent Regulator (IdeR) of Mycobacterium avium subsp. paratuberculosis - (Abstract)

Janagama, H.K., Bannantine, J.P., Rodriguez, M., Smith, I., Sreevatsan, S. 2007. Identification and Characterization of Iron Dependent Regulator (IdeR) of Mycobacterium avium subsp. paratuberculosis [abstract]. Poster #275.

Experimental Infection of White-tailed Deer (Odocoileus virginianus) with Mycobacterium avium subsp. paratuberculosis - (Peer Reviewed Journal)

Palmer, M.V., Stabel, J.R., Waters, W.R., Bannantine, J.P., Miller, J.M. 2007. Experimental Infection of White-tailed Deer (Odocoileus virginianus) with Mycobacterium avium subsp. paratuberculosis. Journal of Wildlife Diseases. 43(4):597-608.

Autoreactive Antibodies are Present in Sheep with Johne's Disease and Cross-react with Mycobacterium avium subsp. paratuberculosis Antigens - (Peer Reviewed Journal)

Berger, S., Bannantine, J.P., Griffin, J.F. 2007. Autoreactive Antibodies are Present in Sheep with Johne's Disease and Cross-react with Mycobacterium avium subsp. paratuberculosis Antigens. Microbes and Infection. 9(2007):963-970.

Mycobacterial Bacilli Are Metabolically Active during Chronic Tuberculosis in Murine Lungs: Insights from Genome-Wide Transcriptional Profiling - (Peer Reviewed Journal)

Talaat, A.M., Ward, S.K., Wu, C., Rondon, E., Tavano, C., Bannantine, J.P., Lyons, R., Johnston, S.A. 2007. Mycobacterial Bacilli are Metabolically Active during Chronic Tuberculosis in Murine Lungs: Insights from Genome-Wide Transcriptional Profiling. Journal of Bacteriology. 189(11):4265-4274.

Development and Characterization of Monoclonal Antibodies and Aptamers Against Major Antigens of Mycobacterium avium subsp. paratuberculosis - (Peer Reviewed Journal)

Bannantine, J.P., Radosevich, T.J., Stabel, J.R., Sreevatsan, S., Kapur, V., Paustian, M. 2007. Development and Characterization of Monoclonal Antibodies and Aptamers Against Major Antigens of Mycobacterium avium subsp. paratuberculosis. Clinical and Vaccine Immunology. 14(5):518-526.

Genomics and vaccine development - (Peer Reviewed Journal)

Gay, C.G., Zuerner, R., Bannantine, J.P., Lillehoj, H.S., Zhu, J., Green, R.D., Pastoret, P.P. 2007. Genomics and vaccine development. OIE Rev. Sci Tech. 26:49-67.

Production and Characterization of Monoclonal Antibodies Against a Major Membrane Protein of Mycobacterium avium subsp. paratuberculosis - (Peer Reviewed Journal)

Bannantine, J.P., Radosevich, T.J., Stabel, J.R., Berger, S., Griffin, J.F., Paustian, M. 2007. Production and Characterization of Monoclonal Antibodies Against a Major Membrane Protein of Mycobacterium avium subsp. paratuberculosis. Clinical and Vaccine Immunology. 14(3):312-317.

Proteome and Differential Expression Analysis of Membrane and Cytosolic Proteins from Mycobacterium avium subsp. paratuberculosis Strains K-10 and 187. - (Peer Reviewed Journal)

Radosevich, T.J., Reinhardt, T.A., Lippolis, J.D., Bannantine, J.P., Stabel, J.R. 2007. Proteome and Differential Expression Analysis of Membrane and Cytosolic Proteins from Mycobacterium avium subsp. paratuberculosis Strains K-10 and 187. Journal of Bacteriology. 189(3):1109-1117.

Rapid Expression of Mycobacterium avium subsp. paratuberculosis Recombinant Proteins for Antigen Discovery - (Peer Reviewed Journal)

Li, L., Munir, S., Bannantine, J.P., Sreevatsan, S., Kanjilal, S., Kapur, V. 2007. Rapid Expression of Mycobacterium avium subsp. paratuberculosis Recombinant Proteins for Antigen Discovery. Clinical and Vaccine Immunology. 14(1):102-105.

Novel Detection Method for Mycobacterium Avium Subsp. Paratuberculosis Using Surface-Enhanced Raman Scattering Based Immunoassays - (Abstract)

Yakes, B.J., Lipert, R.J., Bannantine, J.P., Porter, M.D. 2006. Novel detection method for Mycobacterium avium subsp. paratuberculosis using surface-enhanced Raman scattering based immunoassays [abstract]. 232nd American Chemical Society National Meeting.

Isolation of High-Affinity Single-Chain Antibodies against Mycobacterium avium subsp. paratuberculosis Surface Proteins from Sheep with Johne's Disease - (Peer Reviewed Journal)

Berger, S., Hinz, D., Bannantine, J.P., Griffin, J.F. 2006. Isolation of High-Affinity Single-Chain Antibodies against Mycobacterium avium subsp. paratuberculosis Surface Proteins from Sheep with Johne's Disease. Clinical and Vaccine Immunology.13(9):1022-1029.

Mycobacterium avium in Pygmy Rabbits (Brachylagus Idahoensis): 28 Cases - (Peer Reviewed Journal)

Harrentien, L.A., Finnegan, M.V., Woodford, N.L., Mansfield, K.G., Waters, W.R., Bannantine, J.P., Paustian, M., Garner, M.M., Bakke, A.C., Peloquin, C.A. 2006. Mycobacterium avium in Pygmy Rabbits (Brachylagus Idahoensis): 28 Cases. Journal of Zoo and Wildlife Medicine. 37(4):498-512.

Comparative Genomics of Metabolic Pathways in Mycobacterium Species: Gene Duplication, Gene Decay and Lateral Gene Transfer - (Peer Reviewed Journal)

Marri, P.R., Bannantine, J.P., Bolding, G.B. 2006. Comparative genomics of metabolic pathways in Mycobacterium species: gene duplication, gene decay and lateral gene transfer. Federation of European Microbiological Societies Microbiology Reviews.30(6)906-925.

Comparative Transcriptional Analysis of Human Macrophages Exposed to Animal and Human isolates of Mycobacterium avium subspecies paratuberculosis with Diverse Genotypes - (Peer Reviewed Journal)

Motiwala, A.S., Janagama, H.K., Paustian, M., Zhu, X., Bannantine, J.P., Kapur, V., Sreevatsan, S. 2006. Comparative Transcriptional Analysis of Human Macrophages Exposed to Animal and Human Isolates of Mycobacterium avium Subspecies paratuberculosis with Diverse Genotypes. Infection and Immunity.74(11):6046-6056.

A Highly Sensitive and Subspecies-Specific Surface Antigen Enzyme-Linked Immunosorbent Assay for the Diagnosis of Johne's Disease - (Peer Reviewed Journal)

Eda, S., Bannantine, J.P., Waters, W.R., Mori, Y., Whitlock, R.H., Scott, M.C., Speer, C.A. 2006. A Highly Sensitive and Subspecies-Specific Surface Antigen Enzyme-Linked Immunosorbent Assay for the Diagnosis of Johne's Disease. Clinical and Vaccine Immunology.13(8)837-844.

Has Mycobacterium Avium Subsp. Paratuberculosis Acquired Virulence Factors to Compensate for the Absence of Pe/pgrs/ppe Genes? - (Abstract)

Marri, P.R., Bannantine, J.P., Golding, G.B. 2006. Has Mycobacterium avium subsp. paratuberculosis acquired virulence factors to compensate for the absence of PE/PGRS/PPE genes? [abstract]. Molecular Biology and Evolution Conference.

Development and Use of a Mycobacterium Avium Subsp. Paratuberculosis Partial Protein Array for Discovery of Novel Antigens - (Abstract)

Bannantine, J.P., Waters, W.R., Stabel, J.R., Kapur, V., Paustian, M. 2006. Development and use of a Mycobacterium avium subsp. paratuberculosis partial protein array for discovery of novel antigens [abstract]. In: Proceedings of the American Society for Microbiology 106th Annual Meeting. May 20-25, 2006. Orlando, Florida. 2006 CDROM.

Proteome and Differential Expression Analysis of Membrane and Cytosolic Protein from Mycobacterium Avium Subs Paratuberculosis Strains K10 and 187 - (Abstract)

Radosevich, T.J., Stabel, J.R., Bannantine, J.P., Lippolis, J.D., Reinhardt, T.A. 2006. Proteome and Differential Expression Analysis of Membrane and Cytosolic Protein from Mycobacterium avium subs paratuberculosis Strains k10 and 187 [abstract]. American Society for Microbiology. p. 112.

A Novel Elisa for the Diagnosis of Mycobacterium Avium Subsp. Paratuberculosis Infections (Johne's Disease) in Cattle - (Abstract)

Eda, S., Scott, M.C., Bannantine, J.P., Waters, W.R., Yoshiyuki, M., Whitlock, R.H., Speer, C.A. 2006. A Novel ELISA for the Diagnosis of Mycobacterium avium subsp. paratuberculosis infections (Johne's disease) in Cattle [abstract]. American Society for Microbiology 106th Annual Meeting.

Identification of Differences in the Protein Content of Mycobacterium Avium Subspecies Paratuberculosis Purified Protein Derivative Preparations with Different Skin Test Specificities - (Abstract)

Paustian, M., Robbe Austerman, S., Lippolis, J.D., Stabel, J.R., Bannantine, J.P. 2006. Identification of Differences in the Protein Content of Mycobacterium avium subspecies paratuberculosis Purified Protein Derivative Preparations with Different Skin Test Specificities [abstract]. American Society for Microbiology. Paper No. U-016.

A Novel Enzyme-Linked Immunosorbent Assay for Diagnosis of Mycobacterium Avium Subsp. Paratuberculosis Infections (Johne's Disease) in Cattle - (Peer Reviewed Journal)

Speer, C.A., Scott, M.C., Bannantine, J.P., Waters, W.R., Mori, Y., Whitlock, R.H., Eda, S. 2006. A Novel Enzyme-Linked Immunosorbent Assay for Diagnosis of Mycobacterium avium subsp. paratuberculosis Infections (Johne's Disease) in Cattle. Clinical and Vaccine Immunology. 13(5):535-540.

Early Antibody Responses to Experimental Mycobacterium Bovis Infection of Cattle - (Peer Reviewed Journal)

Waters, W.R., Palmer, M.V., Thacker, T.C., Bannantine, J.P., Vordermeier, H.M., Hewinson, R.G., Greenwald, R., Esfandiari, J., Mcnair, J., Pollock, J.M. 2006. Early Antibody Responses to Experimental Mycobacterium bovis Infection of Cattle. Clinical and Vaccine Immunology. 13(6):648-654.

The Ability of Mycobacterium Avium Subsp. Paratuberculosis to Enter Bovine Epithelial Cells Is Influenced by Preexposure to a Hyperosmolar Environment and Intracellular Passage in Bovine Mammary Epithelial Cells - (Peer Reviewed Journal)

Patel, D., Danelishvili, L., Yamazaki, T., Marta, A., Paustian, M., Bannantine, J.P., Meunier-Goddik, L., Bermudez, L.E. 2006. The ability of Mycobacterium avium subsp. paratuberculosis to enter bovine epithelial cells is influenced by preexposure to a hyperosmolar environment and intracellular passage in bovine mammary epithelial cells. Infection and Immunity. 74(5):2849-2855.

An Oligonucleotide Microarray Designed for Functional Genomic Analyses of Mycobacterium Avium Subspecies Paratuberculosis - (Abstract)

Paustian, M., Bannantine, J.P. 2006. An oligonucleotide microarray designed for functional genomic analyses of Mycobacterium avium subspecies paratuberculosis [abstract]. Poster No. 2.

Lateral Gene Transfer in Mycobacterium Avium Subspecies Paratuberculosis - (Peer Reviewed Journal)

Marri, P.R., Bannantine, J.P., Paustian, M., Golding, G.B. 2006. Lateral gene transfer in Mycobacterium avium subspecies paratuberculosis. Canadian Journal of Microbiology. 52:560-569.

Genomic Comparison of Mycobacterium Avium Subsp. Paratuberculosis Sheep and Cattle Strains by Microarray Hybridization - (Peer Reviewed Journal)

Marsh, I.B., Bannantine, J.P., Paustian, M., Tizard, M.L., Kapur, V., Whittington, R.J. 2006. Genomic Comparison of Mycobacterium avium subsp. paratuberculosis Sheep and Cattle Strains by Microarray Hybridization. Journal of Bacteriology. 188(6): 2290-2293.

Identification of Diagnostic Proteins in Mycobacterium Avium Subspecies Paratuberculosis by Whole Genome Analysis Approach - (Book/Chapter)

Bannantine, J.P., Paustian, M. 2006. Identification of diagnostic proteins in Mycobacterium avium subspecies paratuberculosis by whole genome analysis approach. In: O'Connor, L., editor. Methods im Molecular Biology: Diagnostic Bacteriology Protocols. 2nd edition. Totowa, NJ: Humana Press. p. 185-196.

DNA Vaccines Against Tuberculosis - (Book/Chapter)

Chacon, O., Bannantine, J.P. 2006. Dna vaccines against tuberculosis. In: Thoen, C.O., Steele, J.H., Gilsdorf, M.J., editors. Mycobacterium Bovis: Infection in Animals and Humans. 2nd edition. Ames, IA: Blackwell Publishing. p. 285-304.

The Mycobacterium Avium Subspecies Paratuberculosis Genome and Its Initial Applications - (Abstract)

Bannantine, J.P., Kapur, V., Stabel, J.R., Paustian, M. 2005. The Mycobacterium avium subspecies paratuberculosis Genome and its Initial Applications [abstract]. AAVI-ACVM Symposium at the Conference of Research Workers in Animal Diseases. p. 16.

A Multi-Facted Approach to Mycobacterium Avium Subsp. Paratuberculosis Research in the Agricultural Research Service - (Proceedings/Symposium)

Stabel, J.R., Bannantine, J.P., Paustian, M., Robbe Austerman, S. 2005. A Multi-facted Approach to Mycobacterium avium subsp. paratuberculosis Research in the Agricultural Research Service. UJNR Food & Agricultural Panel Proceedings. p. 120-123.

An Igg1 Elisa for Diagnosis of Johne's Disease in Red Deer (Cervus Elaphus) - (Peer Reviewed Journal)

Griffin, J.F., Spittle, E., Rodgers, C.R., Liggett, S., Cooper, M., Bakker, D., Bannantine, J.P. 2005. An IgG1 ELISA for Diagnosis of Johne's Disease in Red Deer (Cervus elaphus). Clinical and Diagnostic Laboratory Immunology. p. 1401-1409.

Field Application of Antibody-Based Tests for the Detection of Tuberculous Deer in Michigan, Usa - (Abstract)

Waters, W.R., Palmer, M.V., Bannantine, J.P., Zimmerman, S., Schmitt, S.M., O'Brien, J., Greenwald, R., Esfandiari, J., Andersen, P., Mcnair, J. 2005. Field Application of Antibody-based Tests for the Detection of Tuberculous deer in Michigan, USA [abstract]. International Conference on Mycobacterium bovis. p. 70.

Recent Developments in the Molecular Biology of Mycobacterium Avium Subsp. Paratuberculosis - (Proceedings/Symposium)

Bannantine, J.P. 2005. Recent developments in the molecular biology of Mycobacterium avium subsp. paratuberculosis. Proceedings of the 8th International Colloquium on Paratuberculosis, August 13-17, 2005, Copenhagen, Denmark. p, 345-351.

Development and Use of a Mycobacterium Avium Subsp. Paratuberculosis Partial Protein Array for Discovery of Novel Antigens - (Abstract)

Bannantine, J.P., Waters, W.R., Palmer, M.V., Kapur, V., Stabel, J.R., Paustian, M. 2006. Development and use of a mycobacterium avium subsp. paratuberculosis partial protein array for discovery of novel antigens [abstract]. International Colloquium on Paratuberculosis. p. 146.

Production and Characterization of Monoclonal Antibodies, Aptamers and Single Chain Antibodies to Mycobacterium Avium Subsp. Paratuberculosis - (Proceedings/Symposium)

Bannantine, J.P., Sreevatsan, S., Tizard, M., Michalski, V., Berger, S., Griffin, F., Paustian, M. 2005. Production and Characterization of Monoclonal Antibodies, Aptamers and Single Chain Antibodies to Mycobacterium avium subsp. paratuberculosis. In: Proceedings of the 8th International Colloquium on Paratuberculosis, August 13-17, 2005, Copenhagen, Denmark. p. 358-365.

Genomic and Proteomic Comparative Study of the Sheep and Cattle Strains of Mycobacterium Avium Subsp. Paratuberculosis - (Proceedings/Symposium)

Marsh, I.B., Bannantine, J.P., Tizard, M.L., Whittington, R.J. 2005. Genomic and proteomic comparative study of the sheep and cattle strains of Mycobacterium avium subsp. paratuberculosis. In: Proceedings of the 8th International Colloquium on Paratuberculosis, August 13-17, 2005, Copenhagen, Denmark. p. 381-392.

Comparative Genomic Analysis of Mycobacterium Avium Subspecies Paratuberculosis Isolates Obtained from Multiple Host Species - (Proceedings/Symposium)

Paustian, M., Zhu, Z., Robbe Austerman, S., Sreevatsan, S., Kapur, V., Bannantine, J.P. 2006. Comparative genomic analysis of Mycobacterium avium subspecies paratuberculosis isolates obtained from multiple host species. In: Proceedings of the 8th International Colloquium on Paratuberculosis, August 13-17, 2005, Copenhagen, Denmark. p. 393-400.

A Multi-Facted Approach to Mycobacterium Avium Subsp. Paratuberculosis Research in the Agricultural Research Service - (Abstract)

Stabel, J.R., Bannantine, J.P., Paustian, M., Robbe Austerman, S. 2005. A Multi-facted Approach to Mycobacterium avium subsp. paratuberculosis Research in the Agricultural Research Service [abstract]. UJNR Food & Agricultural Panel Abstracts. p. 15.

The Complete Genome Sequence of Mycobacterium Avium Subsp. Paratuberculosis - (Peer Reviewed Journal)

Li, L., Bannantine, J.P., Zhang, Q., Amonsin, A., May, B.J., Alt, D.P., Banerji, N., Kanjilal, S., Kapur, V. 2005. The Complete Genome Sequence of Mycobacterium avium subsp. paratuberculosis. Proceedings of the National Academy of Sciences. 102:12344-12349.

Lateral Gene Transfer in Mycobacterium Avium Subsp. Paratuberculosis - (Abstract)

Reddy, M.P., Bannantine, J.P., Golding, M.B. 2005. Lateral gene transfer in mycobacterium avium subsp. paratuberculosis [abstract]. Annual Meeting of the International Society for Computational Biology.

New Method of Serological Testing for Mycobacterium Avium Subsp. Paratuberculosis (Johne's Disease) by Flow Cytometry - (Peer Reviewed Journal)

Shigetoshi, E., Elliot, B., Scott, M.C., Waters, W.R., Bannantine, J.P., Speer, C.A. 2005. New Method of Serological Testing for Mycobacterium Avium subsp. Paratuberculosis (Johne's Disease) by Flow Cytometry. Foodborne Pathogens and Disease. 2(3):250-62.

Expression Library Immunization Confers Protection Against Mycobacterium Avium Subsp. Paratuberculosis Infection - (Peer Reviewed Journal)

Huntley, J.F., Stabel, J.R., Paustian, M., Reinhardt, T.A., Bannantine, J.P. 2005. Expression Library Immunization Confers Protection against Mycobacterium avium subsp. paratuberculosis Infection. Infection and Immunity. 73(10):6877-6884.

Development of a Nested Pcr Method Targeting a Unique Multicopy Element, Ismap02, for Detection of Mycobacterium Avium Subsp. Paratuberculosis in Fecal Samples - (Peer Reviewed Journal)

Stabel, J.R., Bannantine, J.P. 2005. Development of a Nested PCR Method Targeting a Unique Multicopy Element, ISMap02, for Detection of Mycobacterium avium subsp. paratuberculosis in Fecal Samples. Journal of Clinical Microbiology. 43(9):4744-4750.

Tuberculin Skin Testing Boosts Antibody Responses in Reindeer (Rangifer Tarandus) Experimentally Infected with Mycobacterium Bovis - (Peer Reviewed Journal)

Waters, W.R., Palmer, M.V., Bannantine, J.P., Greenwald, R., Esfandiari, J., Andersen, P., Mcnair, J., Pollock, J.M., Lyashchenko, K. 2005. Antibody responses in reindeer (rangifer tarandus) experimentally infected with mycobacterium bovis. Clinical and Diagnostic Laboratory Immunology. 12(6):727-35.

Comparative Genomic Hybridizations Reveal Genetic Regions Within Mycobacterium Avium Complex Mycobacteria That Are Divergent from Mycobacterium Avium Subsp. Paratuberculosis Isolates - (Peer Reviewed Journal)

Paustian, M., Kapur, V., Bannantine, J.P. 2005. Comparative genomic hybridizations reveal genetic regions within mycobacterium avium complex mycobacteria that are divergent from mycobacterium avium subsp. paratuberculosis isolates. Journal of Bacteriology. 187(7):2406-15.

Immunoreactivity of the Mycobacterium Avium Subsp. Paratuberculosis 19-Kda Lipoprotein - (Peer Reviewed Journal)

Huntley, J., Stabel, J.R., Bannantine, J.P. 2005. Immunoreactivity of the mycobacterium avium subsp. paratuberculosis 19-kda lipoprotein. BMC Microbiology. 5(1):1-8.

Comparison of Diagnostic Detection Methods for Mycobacterium Avium Subsp. Paratuberculosis from North American Bison - (Peer Reviewed Journal)

lHuntley, J., Whitlock, R., Bannantine, J.P., Stabel, J.R. 2005. Comparison of diagnostic detection methods for mycobacterium avium subsp. paratuberculosis from North American bison. Journal of Veterinary Diagnostic Investigation. 42(1):42-51.

Development and Evaluation of a New Pcr Test for the Detection of Mycobacterium Avium Subsp. Paratuberculosis - (Abstract)

Stabel, J.R., Bannantine, J.P., Paustian, M. 2004. Development and Evaluation of a new PCR test for the detection of Mycobacterium avium subsp. paratuberculosis [abstract]. American Association of Veterinary Laboratory Diagnosticians.

Antigen Recognition by Serum Antibodies in White-Tailed Deer (Odocoileus Virginianus) Experimentally Infected with Mycobacterium Bovis - (Abstract)

Waters, W.R., Palmer, M.V., Bannantine, J.P., Whipple, D.L., Greenwald, R., Esfandiari, J., Pollack, J.M., Mcnair, J., Andersen, P., Lyashchencko, K. 2004. Antigen recognition by serum antibodies in white-tailed deer (odocoileus virginianus) experimentally infected with mycobacterium bovis[abstract]. Wildlife Disease Association. p. 299.

Antigen Recognition by Serum Antibodies in White-Tailed Deer (Odocoileus Virginianus) Experimentally Infected with Mycobacterium Bovis - (Peer Reviewed Journal)

Waters, W.R., Palmer, M.V., Bannantine, J.P., Whipple, D.L., Greenwald, R., Esfandiari, J., Andersen, P., Mcnair, J., Pollock, J.M., Lyashchenko, K.P. 2004. Antigen recognition by serum antibodies in white-tailed deer (odocoileus virginianus) experimentally infected with mycobacterium bovis. Clinical and Diagnostic Laboratory Immunology. 11(5):849-55.

Whole-Genome Transcriptional Response of Mycobacterium Avium Subspecies Paratuberculosis to Mycbactin J at: Asm General Meeting 2004. - (Abstract)

Paustian, M., Kapur, V., Bannantine, J.P. 2004. Whole-genome Transcriptional Response of Mycobacterium avium subspecies paratuberculosis to Mycbactin J [abstract]. American Society of Microbiologists 104th General Meeting, May 23-27, 2004, New Orleans, LA. 2004 CDROM.

Differentiation of Mycobacterium Bovis Infection of Cattle from M. Avium Subsp. Avium and M. Avium Subsp. Paratuberculosis Infection Using a Recombinant Esat-6:cfp-10 Fusion Protein - (Peer Reviewed Journal)

Waters, W.R., Nonnecke, B.J., Palmer, M.V., Robbe Austerman, S., Bannantine, J.P., Stabel, J.R., Whipple, D.L., Payeur, J.B., Estes, D.M., Pitzer, J.E., Minion, F.C. 2004. Use of recombinant esat-6:cfp-10 fusion protein for differentiation of infections of cattle by mycobacterium bovis and by m.avium subsp. avium and m. avium subsp. paratuberculosis. Clinical and Diagnostic Laboratory Immunology. 11:729-735.

Charatetrization of Novel Coding Sequences Specific to Mycobacterium Avium Subsp. Paratuberculosis: Implications for Diagnosis of Johne's Disease - (Peer Reviewed Journal)

Paustian, M., Amonsin, A., Kapur, V., Bannantine, J.P. 2004. Charatetrization of novel coding sequences specific to mycobacterium avium subsp. paratuberculosis: implications for diagnosis of johne's disease. Journal of Clinical Microbiology. 42:2675-2681.

Mycobacterium Paratuberculosis: Genome to Disease Control - (Abstract)

Stabel, J.R., Bannantine, J.P., Robbe Austerman, S., Paustian, M., Huntley, J. 2004. Mycobacterium paratuberculosis: genome to disease control[abstract]. Meeting Abstract.

A Multi-Locus Short Sequence Repeat Sequencing Approach for Mycobacterium Avium Subspecies Paratuberculosis Stain Differentiation - (Peer Reviewed Journal)

Amonsin, A., Li, L., Zhang, Q., Bannantine, J.P., Motiwala, A., Sreevatsan, S., Kapur, V. 2004. A multi-locus short sequence repeat sequencing approach for mycobacterium avium subspecies paratuberculosis stain differentiation. Journal of Clinical Microbiology. 42:169-1702.

Experimental Mycobacterium Avium Subsp. Paratuberculosis Infection of Calves: Early Induction of a Concurrent Humora and Cellular Immune Response - (Abstract) - (02-Dec-03)

Application of the Genome Sequences to Address Concerns That Mycobacterium Avium Subspecies Paratuberculosis Might Be a Foodborne Pathogen - (Peer Reviewed Journal)

Bannantine, J.P., Barletta, R.G., Stabel, J.R., Paustian, M., Kapur, V. 2004. Application of the genome sequences to address concerns that mycobacterium avium subspecies paratuberculosis might be a foodborne pathogen. Foodborne Pathogens and Disease. 1:3-15.

Experimental Mycobacterium Avium Subsp. Paratuberculosis Infection of Calces:early Induction of a Concurrent Humoral and Cellular Immune Response - (Abstract) - (09-Nov-03)

Insights from the Mycobacterium Avium Subspecies Paratuberculosis Genome Project - (Abstract) - (02-Oct-03)

A Set of Recombinant Antigens from Mycobacterium Avium Subspecies Paratuberculosis with Potential of Use in the Serodiagnosis of Johne's Disease - (Abstract) - (28-Sep-03)

Genomic Comparison of Mycobacterium Avioum Subspecies Paratuberculosis with Other Mycobacterium Avium Complex Members Using DNA Microarrays - (Abstract) - (28-Sep-03)

The Genome Sequence of Mycobacterium Avium Subsp Paratuberculosis - (Abstract) - (28-Sep-03)

Using Mycobacterium Avium Subspecies Paratuberculosis Genomics to Combat Johne's Disease - (Abstract) - (18-Sep-03)

Construction and Utilization of a Mycobacterium Avium Subsp. Paratuberculosis Whole-Genome Microarray - (Abstract) - (18-Sep-03)

Expressionand Immunogenicity of Proteins Encoded by Sequences Specific to Mycobacterium Avium Subsp. Paratuberculosis - (Peer Reviewed Journal)

Bannantine, J.P., Hansen, J.K., Paustian, M., Amonsin, A., Li, L.L., Stabel, J.R., Kapur, V. 2004. Expressionand immunogenicity of proteins encoded by sequences specific to mycobacterium avium subsp. paratuberculosis. Journal of Clinical Microbiology. 42:106-114.

Evaluation of Novel Mycobacterium Avium Supsp. Paratuberculosis Antigens As Potential Diagnostic Reagents - (Abstract) - (17-Jul-03)

Construction and Utilization of a Mycobacterium Subsp. Paratuberculosis Whole-Genome Microarray - (Abstract) - (17-Jul-03)

Experimental Mycobacterium Avium Subsp. Paratuberculosis Infection of Calves: Early Induction of a Humoral and Cellular Immune Response - (Peer Reviewed Journal)

Waters, W.R., Miller, J.M., Palmer, M.V., Stabel, J.R., Jones, D.E., Koistinen, K.A., Steadham, E.M., Hamilton, M.J., Davis, W.C., Bannantine, J.P. 2003. Experimental mycobacterium avium subsp. paratuberculosis infection of calves: early induction of a humoral and cellular immune response. Infection and Immunity. 71:5130-5138.

Genomic Hemogeneity Between Mycobacterium Avium and Mycobacterium Avium Subsp. Paratuberculosis Belies Their Divergent Growth Rates - (Peer Reviewed Journal)

Bannantine, J.P., Zhang, Q., Li, L., Kapur, V. 2003. Genomic hemogeneity between mycobacterium avium and mycobacterium avium subsp. paratuberculosis belies their divergent growth rates. Biomed Central (BMC) Microbiology.

The Mycobacterium Avium Supspecies Paratuberculosis 35 Kda Protein Plays a Role in Invasion of Bovine Epithelial Cells - (Peer Reviewed Journal)

Bannantine, J.P., Huntley, J.F., Miltner, E., Stabel, J.R., Bermudez, L.E. 2003. The mycobacterium avium supspecies paratuberculosis 35 kda protein plays a role in invasion of bovine epithelial cells. Infection and Immunity.

Molecular Epidemiology of Mycobacterium Avium Subspecies Paratuberculosis: Evidence for Limited Strain Diversity, Strain Sharing, and Identification of Unique Targets for Diagnosis - (Peer Reviewed Journal)

Motiwala, A.S., Strother, M., Amonsin, A., Byrum, B., Naser, S., Stabel, J.R., Shulaw, W., Bannantine, J.P., Kapur, V., Sreevatsan, S. 2003. Molecular epidemiology of mycobacterium avium subspecies paratuberculosis: evidence for limited strain diversity, strain sharing, and identification of unique targets for diagnosis. Journal of Clinical Microbiology.

Identification of Mycobacterium Avium Subsp. Paratuberculosis-Specific Antigens from the Complete Genome Sequence - (Abstract) - (29-Jan-03)