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United States Department of Agriculture

Agricultural Research Service

Related Topics

Robert A Kunkle

Veterinary Medical Science

Phone: (515) 663-7740 ext. 7740
Fax: (515) 663-7255
2300 Dayton Avenue
AMES, IA, 50010-0070

Projects
TRANSMISSION, DIFFERENTIATION, AND PATHOBIOLOGY OF TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES
Appropriated (D)
  Accession Number: 421870

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Chronic wasting disease in bank voles: characterisation of the shortest incubation time model for prion diseases Reprint Icon - (Peer Reviewed Journal)
Di Bari, M.A., Nonno, R., Castilla, J., D'Agostino, C., Pirisinu, L., Riccardi, G., Conte, M., Richt, J., Kunkle, R., Langeveld, J., Vaccari, G., Agrimi, U. 2013. Chronic wasting disease in bank voles: characterisation of the shortest incubation time model for prion diseases. PLoS Pathogens. 9(3):e1003219.
Susceptibility of cattle to the agent of chronic wasting disease from elk after intracranial inoculation - (Peer Reviewed Journal)
Greenlee, J.J., Nicholson, E.M., Smith, J.D., Kunkle, R.A., Hamir, A.N. 2012. Susceptibility of cattle to the agent of chronic wasting disease from elk after intracranial inoculation. Journal of Veterinary Diagnostic Investigation. 24(6):1087-1093.
Correlating levels of type III secretion and secreted proteins with fecal shedding of Escherichia coli O157:H7 in cattle - (Peer Reviewed Journal)
Sharma, V.K., Sacco, R.E., Kunkle, R.A., Bearson, S.M., Palmquist, D.E. 2012. Correlating levels of type III secretion and secreted proteins with fecal shedding of Escherichia coli O157:H7 in cattle. Infection and Immunity. 80(4):1333-1342.
Prolonged incubation time in sheep with prion protein containing lysine at position 171 - (Peer Reviewed Journal)
Greenlee, J.J., Zhang, Xia, Nicholson, E.M., Kunkle, R.A., Hamir, A.N. 2012. Prolonged incubation time in sheep with prion protein containing lysine at position 171. Journal of Veterinary Diagnostic Investigation. 24(3):554-558.
Experimental Interspecies Transmission Studies of the Transmissible Spongiform Encephalopathies to Cattle: Comparison to Bovine Spongiform Encephalopathy in Cattle - (Review Article)
Hamir, A.N., Kehrli, Jr., M.E., Kunkle, R.A., Greenlee, J.J., Nicholson, E.M., Richt, J.A., Miller, J.M., Cutlip, R.C. 2011. Experimental interspecies transmission studies of the transmissible spongiform encephalopathies to cattle: comparison to bovine spongiform encephalopathy in cattle. Journal of Veterinary Diagnostic Investigation. 23(3):407-420.
White-Tailed Deer Susceptible to Scrapie by Natural Route of Infection - (Abstract Only)
Greenlee, J.J., Smith, J.D., Kunkle, R.A. 2010. White-tailed deer susceptible to scrapie by natural route of infection [abstract]. American College of Veterinary Pathologists. Paper No. 81.
White-Tailed Deer Susceptible to Scrapie by Natural Route of Infection - (Abstract Only) - (05-Oct-10)
Clinical features in prion protein-deficient and wild-type cattle inoculated with transmissible mink encephalopathy (TME) - (Abstract Only)
Vargas, F., Kuroiwa, Y., Hamir, A.N., Greenlee, J.J., Kunkle, R.A., Kangas, T., Kanthasamy, A., Robl, J., Richt, J. A. 2010. Clinical features in prion protein-deficient and wild-type cattle inoculated with transmissible mink encephalopathy (TME) [abstract]. XXVI World Buiatrics Congress 2010, November 14-18, 2010, Santiago, Chile. Available: http://www.kenes.com/buiatrics/cd/pdf/780.pdf.
White-tailed Deer are Susceptible to Sheep Scrapie by Intracerebral Inoculation - (Abstract Only)
Greenlee, J.J., Smith, J.D., Kunkle, R.A. 2010. White-tailed deer are susceptible to sheep scrapie by intracerebral inoculation [abstract]. Prion 4(3):144.
Aspergillosis - (Book / Chapter)
Kunkle, R.A. 2010. Aspergillosis. In: Kahn, C.M., Line, S., editors. The Merck Veterinary Manual. 10th edition. Whitehouse Station, NJ: Merck Publishing. p. 2497-2498.
Experimental Transmission of Chronic Wasting Disease (CWD) from Elk (Cervus elaphus nelsoni) and White-tailed Deer (Odocoileus virginianus) to Fallow Deer (Dama dama) by Intracerebral Route: Final Report - (Peer Reviewed Journal)
Hamir, A.N., Greenlee, J.J., Nicholson, E.M., Kunkle, R.A., Richt, J.A., Miller, J.M., Hall, M. 2011. Experimental transmission of chronic wasting disease (CWD) from elk and white-tailed deer to fallow deer by intracerebral route: final report. Canadian Journal of Veterinary Research. 75(2):152-156.
Retinal Fluorescence Spectroscopy for Diagnosis of Transmissible Spongiform Encephalopathies - (Peer Reviewed Journal)
Adhikary, R., Mukherjee, P., Krishnamoorthy, G., Kunkle, R.A., Casey, T.A., Rasmussen, M.A., Petrich, J.W. 2010. Fluorescence Spectroscopy of the Retina for Diagnosis of Transmissible Spongiform Encephalopathies. Analytical Chemistry. 82(10):4097-4101.
Detection of PrPSc in Formalin Fixed Paraffin Embedded Tissue by Western Blot Differentiates Classical Scrapie, Nor98 Scrapie, and BSE Reprint Icon - (Peer Reviewed Journal)
Loiacono, C.M., Beckwith, N., Kunkle, R.A., Orcutt, D., Hall, S.M. 2010. Detection of PrPSc in formalin-fixed, paraffin embedded tissue by Western blot differentiates classical scrapie, Nor98 scrapie, and bovine spongiform encephalopathy. Journal of Veterinary Diagnostic Investigation. 22(5):684-689.
Experimental Inoculation of Spiroplasma mirum and Transmissible Mink Encephalopathy (TME) into Raccoons (Procyon lotor) - (Peer Reviewed Journal)
Hamir, A.N., Greenlee, J.J., Stanton, T.B., Smith, J.D., Doucette, S., Kunkle, R.A., Stasko, J.A., Richt, J.A., Kehrli, Jr., M.E. 2011. Experimental inoculation of raccoons (Procyon lotor) with Spiroplasma mirum and transmissible mink encephalopathy (TME). Canadian Journal of Veterinary Research. 75(1):18–24.
Lack of Prion Accumulation in Lymphoid Tissues of Scrapie-affected Sheep with the AA136, QR171 Prion Protein Genotype - (Abstract Only)
Kunkle, R.A., Hamir, A.N., Richt, J., Greenlee, J.J., Nicholson, E.M., Kehrli, Jr., M.E. 2009. Lack of Prion Accumulation in Lymphoid Tissues of Scrapie-affected Sheep with the AA136, QR171 Prion Protein Genotype [abstract]. American Association of Veterinary Laboratory Diagnosticians. Paper No. 186.
Susceptibility of Cattle to First-Passage Intracerebral Inoculation with Chronic Wasting Disease Agent from Elk - (Abstract Only)
Greenlee, J.J., Nicholson, E.M., Kunkle, R.A., Hamir, A.N. Susceptibility of Cattle to First-Passage Intracerebral Inoculation with Chronic Wasting Disease Agent from Elk [abstract]. American College of Veterinary Pathologists Annual Meeting. Veterinary Pathology. 46(5):1058.
Guanidinium Chloride Unfolding of PrP**Sc Exhibits Marked Differences Between Genotypes - (Abstract Only)
Nicholson, E.M., Greenlee, J.J., Kunkle, R.A., Hamir, A.N. 2009. Guanidinium Chloride Unfolding of PrP**Sc Exhibits Marked Differences Between Genotypes [abstract]. Prion 2009. p. 182.
Prolonged Incubation Time in Sheep with QK171 Genotype - (Abstract Only)
Greenlee, J.J., Nicholson, E.M., Kunkle, R.A., Hamir, A.N. 2009. Prolonged Incubation Time in Sheep with QK171 Genotype [abstract]. Prion 2009. p. 120.
Characterization of a U.S. Sheep Scrapie Isolate with Short Incubation Time Reprint Icon - (Peer Reviewed Journal)
Hamir, A.N., Richt, J.A., Kunkle, R.A., Greenlee, J.J., Bulgin, M.S., Gregori, L., Rohwer, R.G. 2009. Characterization of a U.S. Sheep Scrapie Isolate with Short Incubation Time. Veterinary Pathology. 46(6):1205-1212.
Strain-specific virulence of Bordetella hinzii in poultry - (Peer Reviewed Journal)
Register, K.B., Kunkle, R.A. 2009. Strain-Specific Virulence of Bordetella hinzii in Poultry. Avian Diseases. 53(1):50-54.
Experimental transmission of U.S. scrapie agent to neonatal sheep by oral route - (Peer Reviewed Journal)
Hamir, A.N., Kunkle, R.A., Greenlee, J.J., Richt, J.A. 2009. Experimental Oral Transmission of United States Origin Scrapie to Neonatal Sheep. Journal of Veterinary Diagnostic Investigation. 21(1):64-68.
Knocked-out and still walking: prion protein-deficient cattle are resistant to prion disease Reprint Icon - (Abstract Only)
Richt, J.A., Hamir, A.N., Kuroiwa, Y., Vargas, F., Kunkle, R.A., Schonenbrucher, H., Kanthasamy, A., Robl, J.E. 2008. Knocked-out and still walking: prion protein-deficient cattle are resistant to prion disease [abstract]. Rocky Mountain Prion Research Symposium. Paper No. 10.
Serial passage of sheep scrapie inoculum in Suffolk sheep - (Peer Reviewed Journal)
Hamir, A.N., Kunkle, R.A., Richt, J.A., Greenlee, J.J., Miller, J.M. 2009. Serial Passage of Sheep Scrapie Inoculum in Suffolk Sheep. Veterinary Pathology. 46(1):39-44.
Experimental transmission of transmissible spongiform encephalopathies (scrapie, chronic wasting disease, transmissible mink encephalopathy) to cattle and their differentiation from bovine spongiform encephalopathy - (Abstract Only)
Hamir, A.N., Cutlip, R.C., Miler, J.M., Kunkle, R.A., Richt, J.A., Greenlee, J.J., Nicholson, E.M., Kehrli, Jr., M.E. 2008. Experimental Transmission of Transmissible Spongiform Encephalopathies (Scrapie, Chronic Wasting Disease, Transmissible Mink Encephalopathy) to Cattle and Their Differentiation from Bovine Spongiform Encephalopathy [abstract]. American College of Veterinary Pathologists. Paper No. 153. p. 770.
Strain typing of U.S. scrapie strains using a panel of inbred mice - (Abstract Only)
Greenlee, J.J., Kunkle, R.A., Nicholson, E.M., Hamir, A.N., Bulgin, M.S., Richt, J. 2009. Strain Typing of U.S. Scrapie Strains Using a Panel of Inbred Mice [abstract]. American College of Veterinary Pathologists. Paper No. 121. p. 762.
Lack of prion accumulation in lymphoid tissues of scrapie-affected sheep with AA136, QR171 polymorphism type - (Abstract Only)
Kunkle, R.A., Hamir, A.N., Richt, J.A., Greenlee, J.J., Nicholson, E.M., Kehrli, Jr., M.E. 2008. Lack of Prion Accumulation in Lymphoid Tissues of Scrapie-Affected Sheep with AA136, QR171 Polymorphism Type [abtract]. Prion 2008. p. 75.
Experimental transmission of transmissible spongiform encephalopathies (scrapie, chronic wasting disease, transmissible mink encephalopathy) to cattle and their differentiation from bovine spongiform encephalopathy - (Abstract Only)
Hamir, A.N., Kunkle, R.A., Richt, J.A., Greenlee, J.J., Nicholson, E.M., Kehrli, Jr., M.E. 2008. Experimental Transmission of Transmissible Spongiform Encephalopathies (Scrapie, Chronic Wasting Disease, Transmissible Mink Encephalopathy) to Cattle and their Differentiation from Bovine Spongiform Encephalopathy [abstract]. Prion 2008. p. 65.
Wasting and neurologic signs associated with cerebrovascular mineralization in a white-tailed deer (Odocoileu virginianus) - (Peer Reviewed Journal)
Hamir, A.N., Palmer, M.V., Kunkle, R.A. 2008. Wasting and Neurologic Signs in a White-Tailed Deer (Odocoileus virginianus) Not Associated with Abnormal Prion Protein. Journal of Wildlife Diseases. 44(4):1045-1050.
Western-blot detection of PrP**sc in archived paraffin-embedded brainstem from scrapie-affected sheep - (Peer Reviewed Journal)
Kunkle, R.A., Nicholson, E.M., Lebepe-Mazur, S., Orcutt, D.L., Srinivas, M.L., Greenlee, J.J., Alt, D.P., Hamir, A.N. 2008. Western blot detection of PrP**sc in archived paraffin-embedded brainstem from scrapie-affected sheep. Journal of Veterinary Diagnostic Investigation. 20(4):522-526.
Strain-specific virulence of Bordetella hinzii in turkeys - (Abstract Only)
Register, K.B., Kunkle, R.A. 2008. Strain-specific virulence of Bordetella hinzii in turkeys [abstract]. American Society for Microbiology Annual Meeting. Poster No. Z-023.
Experimental transmission of chronic wasting disease (CWD) of elk (Cervus elaphus nelsoni), white-tailed deer (Odocoileus virginianus), and mule deer (Odocoileus hemionus hemionus) to white-tailed deer by intracerebral route Reprint Icon - (Peer Reviewed Journal)
Hamir, A.N., Richt, J., Miller, J.M., Kunkle, R.A., Hall, S., Nicholson, E.M., Orourke, K.I., Greenlee, J.J., Williams, E.S. 2008. Experimental transmission of chronic wasting disease (CWD) of elk (Cervus elaphus nelsoni), white-tailed deer (Odocoileus virginianus), and mule deer (Odocoileus hemionus hemionus) to white-tailed deer by intracerebral route. Veterinary Pathology. 45(3):297-306.
Preliminary observations on the experimental transmission of chronic wasting disease (CWD) from elk and white-tailed deer to fallow deer - (Peer Reviewed Journal)
Hamir, A.N., Kunkle, R.A., Nicholson, E.M., Miller, J.M., Hall, S.M., Schonenbrucher, H., Brunelle, B.W., Richt, J.A. 2008. Preliminary observations on the experimental transmission of chronic wasting disease (CWD) from elk and white-tailed deer to fallow deer. Journal of Comparative Pathology. 138(2-3):121-130.
Preliminary observations on the experimental transmission of chronic wasting disease (CWD) from elk and white-tailed deer to fallow deer (Dama dama) - (Abstract Only)
Hamir, A.N., Kunkle, R.A., Nicholson, E.M., Miller, J.M., Hall, S.M., Schonenbrucher, H., Brunelle, B.W., Richt, J.A. 2007. Preliminary observations on the experimental transmission of chronic wasting disease (CWD) from elk and white-tailed deer to fallow deer (Dama dama) [abstract]. European Society of Veterinary Pathology 25th Annual Meeting. Paper No. 49. p. 104.
Experimental transmission of U.S. scrapie agent by nasal, peritoneal and conjunctival routes to genetically susceptible sheep - (Peer Reviewed Journal)
Hamir, A.N., Kunkle, R.A., Richt, J.A., Miller, J.M., Greenlee, J.J. 2008. Experimental transmission of US scrapie agent by nasal, peritoneal, and conjunctival routes to genetically susceptible sheep. Veterinary Pathology. 45(1):7-11.
Experimental transmission of transmissible spongiform encephalopathies (scrapie, chronic wasting disease, transmissible mink encephalopathy) to cattle and their differentiation from bovine spongiform encephalopathy - (Proceedings)
Hamir, A.N., Cutlip, R.C., Miller, J.M., Kunkle, R.A., Richt, J.A., Greenlee, J.J., Nicholson, E.M., Kehrli, Jr., M.E. 2007. Experimental transmission of transmissible spongiform encephalopathies (scrapie, chronic wasting disease, transmissible mink encephalopathy) to cattle and their differentiation from bovine spongiform encephalopathy. In: Proceedings of the World Association of Veterinary Laboratory Diagnosticians 13th International Symposium, November 11-14, 2007, Melbourne, Australia. p. 29.
Experimental transmission of scrapie agent to susceptible sheep by intralingual and intracerebral inoculation - (Peer Reviewed Journal)
Hamir, A.N., Kunkle, R.A., Bulgin, M.S., Rohwer, R.G., Gregori, L., Richt, J.A. 2008. Experimental transmission of scrapie agent to susceptible sheep by intralingual and intracerebral inoculation. Canadian Journal of Veterinary Research. 72:63-67.
Experimental chronic wasting disease (CWD) in fallow deer - (Abstract Only)
Hamir, A.N., Kunkle, R.A., Nicholson, E.M., Miller, J.M., Hall, S.M., Schonenbrucher, H.H., Richt, J.A. 2007. Preliminary observations on the experimental transmission of chronic wasting disease (CWD) from elk and white-tailed deet to fallow deer [abstract]. Prion 2007. Paper No. PO2.43.
Age-related lesions in laboratory-confined raccoons (Procyon lotor) inoculated with the agent of chronic wasting disease of mule deer - (Peer Reviewed Journal)
Hamir, A.N., Kunkle, R.A., Miller, J.M., Cutlip, R.C., Richt, J.A., Kehrli, Jr., M.E., Williams, E.S. 2007. Age-related lesions in laboratory-confined raccoons (Procyon lotor) inoculated with the agent of chronic wasting disease of mule deer. Journal of Veterinary Diagnostic Investigation. 19(6):680-686.
Detection of the disease-associated isoform of the prion protein in formalin-fixed tissues by Western blot - (Peer Reviewed Journal)
Nicholson, E.M., Kunkle, R.A., Hamir, A.N., Lebepe Mazur, S., Orcutt, D. 2007. Detection of the disease-associated isoform of the prion protein in formalin-fixed tissues by Western blot. Journal of Veterinary Diagnostic Investigation. 19:548-552.
Cross-species transmission of TSE - (Proceedings)
Richt, J.A., Hamir, A.N., Kunkle, R.A., Nicholson, E.M., Greenlee, J.J. 2007. Cross-species transmission of TSE. In: Proceedings of the American College of Veterinary Internal Medicine. 2007 ACVIM Forum, June 6-9, 2007, Seattle, Washington. Paper No. 160.
Age-related lesions in laboratory-confined raccoons (Procyon lotor) inoculated with the agent of chronic wasting disease - (Peer Reviewed Journal)
Hamir, A.N., Kunkle, R.A., Miller, J.M., Cutlip, R.C., Richt, J.A., Kehrli, Jr., M.E., Williams, Jr., E.S. 2007. Age-related lesions in laboratory-confined raccoons (Procyon lotor) inoculated with the agent of chronic wasting disease. Journal of Veterinary Diagnostic Investigation. 19(6):680-686.
Susceptibility of cattle to first-passage intracerebral inoculation with chronic wasting disease agent from white-tailed deer - (Peer Reviewed Journal)
Hamir, A.N., Miller, J.M., Kunkle, R.A., Hall, S.M., Richt, J.A. 2007. Susceptibility of cattle to first-passage intracerebral inoculation with chronic wasting disease agent from white-tailed deer. Veterinary Pathology. 44:487-493.
Transmission of Chronic Wasting Disease of Mule Deer to Suffolk Sheep Following Intracerebral Inoculation - (Abstract Only)
Hamir, A.N., Kunkle, R.A., Cutlip, R.C., Miller, J.M., Williams, E.S., Richt, J.A. 2006. Transmission of chronic wasting disease of mule deer to Suffolk sheep following intracerebral inoculation [abstract]. Conference of Research Workers in Animal Diseases 87th Annual Meeting. Paper No. P34. p. 108.
Detection of PrP**Sc in formalin-fixed tissues by western blot - (Abstract Only)
Nicholson, E.M., Kunkle, R.A., Hamir, A.N. 2006. Detection of PrP**Sc in formalin-fixed tissues by western blot [abstract]. United States-Japan Cooperative Program in Natural Resources. p. 16.
Identification and characterization of two bovine spongiform encephalopathy cases diagnosed in the United States - (Peer Reviewed Journal)
Richt, J.A., Kunkle, R.A., Alt, D., Nicholson, E.M., Hamir, A.N., Czub, S., Kluge, J., Davis, A.J., Hall, S.M. 2007. Identification and characterization of two bovine spongiform encephalopathy cases diagnosed in the United States. Journal of Veterinary Diagnostic Investigation. 19(2):142-154.
Experimental Transmission of Chronic Wasting Disease (Cwd) of Elk (Cervus Elaphus Nelsoni), White-Tailed Deer (Odocoileus Virginianus), and Mule Deer (Odocoileus Hemionus Hemionus) to White-Tailed Deer by Intracerebral Route - (Abstract Only)
Kunkle, R.A., Hamir, A.N., Miller, J.M., Hall, S.M., Richt, J.A., Greenlee, J.J., Williams, E.S. 2006. Experimental transmission of chronic wasting disease (CWD) of elk (Cervus Elaphus Nelsoni), white-tailed deer (Odocoileus Virginianus), and mule deer (Odocoileus Hemionus Hemionus) to white-tailed deer by intracerebral route [abstract]. United States Animal Health Association. p. 221.
Detection of Prp**sc in Formalin-Fixed Tissues by Western Blot - (Abstract Only)
Nicholson, E.M., Hamir, A.N., Kunkle, R.A. 2006. Detection of PrP**sc in formalin-fixed tissues by Western blot [abstract]. United States Animal Health Association. p. 332.
Transmission of chronic wasting disease of mule deer to Suffolk sheep following intracerebral inoculation - (Peer Reviewed Journal)
Hamir, A.N., Kunkle, R.A., Cutlip, R.C., Miller, J.M., Williams, E.S., Richt, J.A. 2006. Transmission of chronic wasting disease of mule deer to Suffolk sheep following intracerebral inoculation. Journal of Veterinary Diagnostic Investigation. 18(6):558-565.
Transmission of Chronic Wasting Disease Agent of Mule Deer (Cwd**md) to Suffolk Sheep by Intracerebral Route - (Abstract Only)
Hamir, A., Kunkle, R., Cutlip, R., Miller, J., Williams, E., Richt, J. 2006. Transmission of chronic wasting disease agent of mule deer (CWD**md) to Suffolk sheep by intracerebral route [abstract]. European Society of Veterinary Pathology 24th Annual Meeting. Paper No. P63. p. 171-172.
Attempted Transmission of Scrapie and Cwd to Swine: Preliminary Findings - (Proceedings)
Greenlee, J.J., Kunkle, R.A. Nicholson, E.M., Lager, K.M., Hamir, A.N. 2006. Attempted transmission of scrapie and CWD to swine: preliminary findings. 19th International Pig Veterinary Society Congress. p. 386.
Determination of Sheep Prion Gene Polymorphisms from Paraffin-Embedded Tissue - (Peer Reviewed Journal)
Kunkle, R.A., Miller, J.M., Alt, D.P., Cutlip, R.C., Cockett, N.E., Wang, S., Richt, J.A., Thomsen, B.V., Hall, S.M. 2006. Determination of sheep prion gene polymorphisms from paraffin-embedded tissue. Journal of Veterinary Diagnostic Investigation. 18(5):443-447.
Experimental Transmission of Transmissible Mink Encephalopathy (Tme) to Cattle by Intracerebral Inoculation - (Abstract Only)
Hamir, A.N., Kunkle, R.A., Miller, J.M., Greenlee, J.J., Richt, J.A. 2006. Experimental transmission of transmissible mink encephalopathy (TME) to cattle by intracerebral inoculation [abstract]. 4th International Veterinary Vaccines and Diagnostics Conference. p. 89. Paper No. PO53.
Cross-Species Tse Transmission Studies at Nadc - (Abstract Only)
Hamir, A.N., Cutlip, R.C., Miller, J.M., Kunkle, R.A., Greenlee, J.J., Richt, J.A. 2006. Cross-species TSE transmission studies at NADC [abstract]. 4th International Veterinary Vaccines and Diagnostics Conference. p. 89. Paper No. PO52.
Experimental Intracerebral and Oral Inoculation of Scrapie to Swine: Preliminary Report - (Abstract Only)
Greenlee, J.J., Kunkle, R.A., Hamir, A.N. 2005. Experimental intracerebral and oral inoculation of scrapie to swine: preliminary report [abstract]. Proceedings of the American Association of Veterinary Laboratory Diagnosticians 48th Annual Conference. p. 38.
Abnormal Prion Protein in Ectopic Lymphoid Tissue in a Kidney of An Asymptomatic White-Tailed Deer Experimentally Inoculated with the Agent of Chronic Wasting Disease - (Peer Reviewed Journal)
Hamir, A.N., Kunkle, R.A., Miller, J.M., Hall, S.M. 2006. Abnormal prion protein in ectopic lymphoid tissue in a kidney of an asymptomatic white-tailed deer experimentally inoculated with the agent of chronic wasting disease. Veterinary Pathology. 43(3):367-369.
Natural and Experimental Prion Diseases of Cattle - (Abstract Only)
Richt, J.A., Hamir, A.N., Kunkle, R.A., Nicholson, E.M., Greenlee, J.J., Miller, J.M., Cutlip, R., Davis, A.J., Hall, S.M. 2005. Natural and experimental prion diseases of cattle [abstract]. Third International Rushmore Conference on Enteric Diseases. Paper No. 14.
Fowl Cholera Reprint Icon - (Book / Chapter)
Kunkle, R.A., Wilson, M.A. 2008. Fowl Cholera. In: OIE Biological Standards Commission, editor. Manual of Diagnostic Tests and Vaccines for Terrestrial Animals 2008: Mammals, Birds and Bees. 6th edition. Paris: Office International Des Epizooties. Chapter 2.3.9. p. 524-530.
Prion Infection of Mucosal Tissue - (Abstract Only)
Bessen, R.A., Dejoia, C., Dlakic, W., Sorg, R., O’Connell, K., Tucker, T., Kunkle, R.A., Hamir, A.N., Richt, J.A. 2005. Prion infection of mucosal tissue [abstract]. TSE Forum, Prion 2005: Between Fundamentals and Society's Needs. p. 31.
First and Second Cattle Passage of Transmissible Mink Encephalopathy (Tme) by Intracerebral Inoculation - (Peer Reviewed Journal)
Hamir, A.N., Kunkle, R.A., Miller, J.M., Bartz, J.C., Richt, J.A. 2006. First and second cattle passage of transmissible mink encephalopathy (TME) by intracerebral inoculation. Veterinary Pathology. 43(2):118-126.
Experimental Second Passage of Chronic Wasting Disease (Cwd(mule Deer)) Agent to Cattle - (Peer Reviewed Journal)
Hamir, A.N., Kunkle, R.A., Miller, J.M., Greenlee, J.J., Richt, J.A. 2006. Experimental second passage of chronic wasting disease (CWD(mule deer)) agent to cattle. Journal of Comparative Pathology. 134(1):63-69.
Experimental Transmission of Transmissible Mink Encephalopathy (Tme) to Cattle by Intracerebral Inoculation - (Abstract Only)
Hamir, A.N., Kunkle, R.A., Miller, J.M., Bartz, J.C., Richt, J.A. 2005. Experimental transmission of transmissible mink encephalopathy (TME) to cattle by intracerebral inoculation [abstract]. American College of Veterinary Pathologists Meeting. 42:706.
Experimental Transmission of Transmissible Spongiform Encephalopathies (Tse) at the National Animal Disease Center, Ames, Iowa: An Update - (Abstract Only)
Hamir, A.N., Cutlip, R.C., Miller, J.M., Kunkle, R.A., Greenlee, J.J., Richt, J.A. 2005. Experimental transmission of transmissible spongiform encephalopathies (TSE) at the National Animal Disease Center, Ames, Iowa: an update [abstract]. American Association of Veterinary Laboratory Diagnosticians. p. 169.
Biochemistry of Prion Diseases - (Abstract Only)
Nicholson, E.M., Greenlee, J.J., Richt, J., Hamir, A.N., Kunkle, R.A., Kehrli, Jr., M.E. 2005. Biochemistry of prion diseases. Association of Analytical Communities International, Midwest Section [abstract]. Abstract No. 601. p. 38.
Second Passage of Sheep Scrapie and Transmissible Mink Encephalopathy (Tme) Agents in Raccoons (Procyon Lotor) - (Peer Reviewed Journal)
Hamir, A.N., Kunkle, R.A., Miller, J.M., Richt, J.A. 2005. Second passage of sheep scrapie and transmissible mink encephalopathy (TME) agents in raccoons (Procyon lotor). Veterinary Pathology. 42(6):844-851.
Experimental Transmission of Transmissible Spongiform Encephalopathies (Tses) at the National Animal Disease Center (Nadc), Ames, Iowa, Usa: An Update - (Abstract Only)
Hamir, A.N., Cutlip, R.C., Miller, J.M., Kunkle, R.A., Greenlee, J.J., Richt, J.A., Bartz, J. 2005. Experimental transmission of transmissible spongiform encephalopathies (TSEs) at the National Animal Disease Center (NADC), Ames, Iowa, USA: An update [abstract]. Annual Wildlife Disease Association Conference. p. 263.
Evaluation of a Diet Free of Animal Protein in Germfree Swine - (Peer Reviewed Journal)
Loynachan, A.T., Pettigrew, J.E., Wiseman, B.S., Kunkle, R.A., Harris, D.L. 2005. Evaluation of a diet free of animal protein in germfree swine. Xenotransplantation. 12:149-155.
Experimental Transmission of Chronic Wasting Disease Agent to Cattle by Intracerebral Route - (Peer Reviewed Journal)
Hamir, A.N., Kunkle, R.A., Cutlip, R.C., Miller, J.M., Orourke, K.I., Williams, E.S., Miller, M.W., Stack, M.J., Chaplin, M.J., Richt, J. 2005. Experimental transmission of chronic wasting disease agent to cattle by intracerebral route. Journal of Veterinary Diagnostic Investigation. 17:276-281.
Characterization of the Recent U.S. Bse Case and Methods for Surveillance - (Proceedings)
Richt, J.A., Kluge, J.P., Alt, D.P., Kunkle, R.A., Hamir, A.N., Czub, S., Davis, A.J., Hall, S.M. 2004. Characterization of the recent U.S. BSE case and methods for surveillance. In: Proceedings of the 108th Annual Meeting of the United States Animal Health Association, October 22-27, 2004, Greensboro, North Carolina. p. 91-92.
Loss of Prion Protein Immunoreactivity after Boiling in Saturated Calcium Hydroxide Solution - (Abstract Only)
Greenlee, J.J., Nicholson, E.M., Hamir, A.N., Richt, J.A., Kunkle, R.A., Noyes, G., Hotzapple, M.T., Kehrli Jr., M.E. 2005. Loss of prion protein immunoreactivity after boiling in saturated calcium hydroxide solution [abstract]. Keystone Symposia: Molecular Mechanisms of Transmissible Spongiform Encephalopathies. Poster No. 125.
Experimental Transmission of Chronic Wasting Disease Agent to Cattle by Intracerebral Route: Final Outcome of the Study - (Abstract Only)
Hamir, A.N., Kunkle, R.A., Richt, J.A., Cutlip, R.C., Miller, J.M., Orourke, K.I., Williams, E.S., Miller, M.W., Stack, M.J., Chaplin, M.J. 2004. Experimental transmission of chronic wasting disease agent to cattle by intracerebral route: final outcome of the study [abstract]. Animal Prion Diseases and the Americas. p. 78.
Identification and Characterization of the U.S. Bovine Spongiform Encephalopathy Case - (Abstract Only)
Richt, J.A., Kluge, J.P., Alt, D.P., Kunkle, R.A., Hamir, A.N., Czub, S., Davis, A.J., Hall, S.M. 2004. Identification and characterization of the U.S. bovine spongiform encephalopathy case [abstract]. Animal Prion Diseases and the Americas. p. 38.
Experimental Transmission of Chronic Wasting Disease Agent to Cattle by Intracerebral Route: Final Outcome of the Study - (Abstract Only)
Hamir, A.N., Kunkle, R.A., Richt, J.A., Cutlip, R.C., Miller, J.M., O'Rourke, K.I., Williams, E.S., Miller, M.W., Stack, M.J., Chaplin, M.J. 2004. Experimental transmission of chronic wasting disease agent to cattle by intracerebral route: final outcome of the study [abstract]. Annual Conference of the American College of Veterinary Pathologists. 41:588.
Experimental Transmission of Sheep Scrapie by Intracerebral and Oral Routes to Genetically Susceptible Suffolk Sheep in the United States - (Peer Reviewed Journal)
Hamir, A.N., Kunkle, R.A., Richt, J.A., Miller, J.M., Cutlip, R.C., Jenny, A.L. 2005. Experimental transmission of sheep scrapie by intracerebral and oral routes to genetically susceptible Suffolk sheep in the United States. Journal of Veterinary Diagnostic Investigation. 17(1):3-9.
Identification and Characterization of the Bovine Spongiform Encephalopathy Case Diagnosed in the U.S. - (Abstract Only)
Richt, J.A., Kluge, J.P., Alt, D.P., Kunkle, R.A., Hamir, A.N., Czub, S., Davis, A.J., Hall, S.M. 2004. Identification and characterization of the bovine spongiform encephalopathy case diagnosed in the United States [Abstract]. XXth International Winter Meeting of the Swiss Society of Neuropathology. Paper No. 13, p. 29.
Fowl Cholera (Avian Pasteurellosis) - (Book / Chapter)
Kunkle, R.A. Fowl cholera (avian pasteurellosis). Office International Epizootics Manual of Diagnostic Tests and Vaccines for Terrestrial Animals. 5th Edition. 2004. Chapt. 2.7.1.1 p. 921-926.
Identification and Characterization of the First U.S. Bovine Spongiform Encephalopathy Case - (Abstract Only)
Richt, J.A., Kluge, J.P., Alt, D.P., Kunkle, R.A., Hamir, A.N., Czub, S., Davis, A.J., Hall, S. 2004. Identification and characterization of the first U.S. bovine spongiform encephalopathy case. Poster created for use by the USDA at a meeting with the Office of International Epizootics.
Transmission of Sheep Scrapie to Elk (Cervus Elaphus Nelsoni) by Intracerebral Inoculation - (Abstract Only)
Hamir, A.N., Miller, J.M., Cutlip, R.C., Richt, J.A., Kunkle, R.A., O'Rourke, K.I., Jenny, A.L., Stack, M.J., Chaplin, M.J. 2003. Transmission of sheep scrapie to elk (Cervus elaphus nelsoni) by intracerebral inoculation. 46th Annual Meeting of the American Association of Veterinary Laboratory Diagnosticians. p. 210.
Experimental Cross-Species Transmission of Chronic Wasting Disease (Cwd-Mule Deer) to Domestic Livestock at the National Animal Disease Center: An Update - (Abstract Only)
Hamir, A.N., Cutlip, R.C., Miller, J.M., Richt, J.A., Kunkle, R.A., Williams, E., Stack, M.J., Chaplin, M.J., Miller, M., O'Rourke, K.I. 2003. Experimental cross-species transmission of chronic wasting disease (CWD-mule deer) to domestic livestock at the National Animal Disease Center: An update [Abstract]. 46th Annual Meeting of the American Association of Veterinary Laboratory Diagnosticians. p. 209.
Transmission of Sheep Scrapie to Elk (Cervus Elaphus Nelsoni) by Intracerebral Inoculation - (Abstract Only)
Hamir, A.N., Miller, J.M., Cutlip, R.C., Richt, J.A., Kunkle, R.A., O'Rourke, K.I., Jenny, A.L., Stack, M.J., Chaplin, M.J. 2003. Transmission of sheep scrapie to elk (Cervus elaphus nelsoni) by intracerebral inoculation [Abstract]. International Conference on Emerging Zoonoses. p. 92.
Experimental Cross-Species Transmission of Chronic Wasting Disease to Domestic Livestock at the National Animal Disease Center: An Update - (Abstract Only)
Hamir, A.N., Cutlip, R.C., Miller, J.M., Richt, J.A., Kunkle, R.A., Williams, E., Stack, M., Miller, M.W., O'Rourke, K.I., Chaplin, M.J. 2003. Experimental cross-species transmission of chronic wasting disease to domestic livestock at the National Animal Disease Center: An update [Abstract]. International Conference on Emerging Zoonoses. p. 91.
Experimental Cross-Species Transmission of Chronic Wasting Disease (Cwd-Mule Deer) to Domestic Livestock at the National Animal Disease Center: An Update - (Abstract Only)
Hamir, A.N., Cutlip, R.C., Miller, J.M., Richt, J.A., Kunkle, R.A., Williams, E., Stack, M., Chaplin, M., Miller, M., O'Rourke, K.I. 2003. Experimental cross-species transmission of chronic wasting disease (CWD-mule deer) to domestic livestock at the National Animal Disease Center: An update [Abstract]. 52nd Annual Wildlife Disease Association Conference. p. 134.
Transmission of Sheep Scrapie to Elk (Cervus Elaphus Nelsoni) by Intracerebral Inoculation - (Abstract Only)
Hamir, A.N., Miller, J.M., Cutlip, R.C., Richt, J.A., Kunkle, R.A., O'Rourke, K.I., Jenny, A.L., Stack, M.J., Chaplin, M.J. 2003. Transmission of sheep scrapie to elk (Cervus elaphus nelsoni) by intracerebral inoculation [Abstract]. 52nd Annual Wildlife Disease Association Annual Meeting. p. 135.
Transmission of Sheep Scrapie to Elk (Cervus Elaphus Nelsoni) by Intracerebral Inoculation - (Abstract Only)
HAMIR, A.N., MILLER, J.M., CUTLIP, R.C., RICHT, J., KUNKLE, R.A., OROURKE, K.I., JENNY, A.L., STACK, M.J., CHAPLIN, M.J. TRANSMISSION OF SHEEP SCRAPIE TO ELK (CERVUS ELAPHUS NELSONI) BY INTRACEREBRAL INOCULATION. DISEASES AT THE INTERFACE BETWEEN DOMESTIC LIVESTOCK AND WILDLIFE SPECIES. 2003. ABSTRACT NO. 6.
Experimental Cross-Species Transmission of Chronic Wasting Disease (Cwd-Mule Deer) to Domestic Livestock at the National Animal Disease Center: An Update - (Abstract Only)
HAMIR, A.N., CUTLIP, R.C., MILLER, J.M., RICHT, J., KUNKLE, R.A., WILLIAMS, E., STACK, M., CHAPLIN, M., MILLER, M., OROURKE, K.I. EXPERIMENTAL CROSS-SPECIES TRANSMISSION OF CHRONIC WASTING DISEASE (CWD-MULE DEER) TO DOMESTIC LIVESTOCK AT THE NATIONAL ANIMAL DISEASE CENTER: AN UPDATE. DISEASES AT THE INTERFACE BETWEEN DOMESTIC LIVESTOCK AND WILDLIFE SPECIES. 2003. ABSTRACT NO. 8.
Transmission of Sheep Scrapie to Elk (Cervus Elaphus Nelsoni) by Intracerebral Inoculation: Final Outcome of the Experiment - (Peer Reviewed Journal)
Hamir, A.N., Miller, J.M., Cutlip, R.C., Kunkle, R.A., Jenny, A.L., Stack, M.J., Chaplin, M.J., Richt, J.A. 2004. Transmission of sheep scrapie to elk (Cervus elaphus nelsoni) by intracerebral inoculation: Final outcome of the experiment. Journal of Veterinary Diagnostic Investigation. 16(4):316-321.
Role of the Dermonecrotic Toxin of Bordetella Bronchiseptica in the Pathogenesis of Respiratory Disease of Swine - (Peer Reviewed Journal) - (27-Sep-01)
Congeners of Smap29 Kill Ovine Pathogens and Induce Utrastructural Damage in Bacterial Cells - (Peer Reviewed Journal) - (08-Aug-01)
Quantitation of Apoptosis in Lymphoid Organs of Poults Exposed to a Heat-Labile Toxin of Bordetella Avium (Proc. 51st Annual Ncadc - Oral Presentation) - (Proceedings) - (09-Nov-00)
Evaluation of the Virulence of a Dermonecrotic Toxin Mutant of Bordetella Bronchiseptica in Swine (For the Int. Pig Vet. Soc. Congr. in Australia, Sept. 17-20, 2000) - (Proceedings) - (07-Jun-00)
Pathology of Bvdv Infection in Neonatal Pigs (Invited Oral Presentation for the Int. Meet. of Pestivirus Infection in Swine, July 6-7, 2000, Ames, Ia) - (Abstract Only) - (02-Jun-00)
Bovine Viral Diarrhea Virus Isolated from Fetal Calf Serum Enhances Pathogenicity of Attenuated Transmissible Gastroenteritis Virus in Neonatal Pigs (Pestivirus Infection in Swine, July 2000, Ames, Iowa) - (Abstract Only) - (25-Apr-00)
Bordetella Avium Dermonecrotic Toxin Induces Apoptosis in Lymphoid Tissues - (Abstract Only) - (07-Oct-99)
Poult Nephropathy Induced by a Bordetella Avium Toxin - (Proceedings) - (03-Oct-99)
Genetic Variation in Response of Turkeys to Experimental Infection with Bordetella Avium (Research Note) - (Peer Reviewed Journal) - (26-Jul-99)
Bordetella Avium Dermonecrotic Toxin Causes Lymphoid Lesions in Mice (Oral Presentation for the Avma/aaap MTG., July 1999) - (Abstract Only) - (10-Jul-99)
Absence of Protection Against Challenge with Aspergillus Fumigatus by Adoptive Transfer of Splenocytes from Convalescent Turkeys - (Peer Reviewed Journal) - (13-Apr-99)
Modulation of the Lymphocyte Repertoire in Mice Following Administration of Bordetella Avium Dermonecrotic Toxin (Poster Presentation for the 99th Asm Gen. Meeting, May 30 - June 3, 1999) - (Abstract Only) - (22-Feb-99)
Bvdv Isolated from Fetal Calf Serum Enhances Pathogenicity of Attenuated Tgev in Neonatal Pigs - (Peer Reviewed Journal) - (03-Dec-98)
Enteric and Lymphoid Organ Lesions in Neonatal Pigs Inolculated with Bvdv Oral Presentation for U.S.-JAPAN Natural Resources Mycoplasmosis Panel Meeting, Nov. 4, 1998 - (Abstract Only) - (27-Oct-98)
Enteritis and Lymphocyte Depletion in Pigs Inoculated with Bovine Viral Diarrhea Virus - (Abstract Only) - (28-Sep-98)
The Influence of Bordetella Avium Infection on Bacterin-Induced Immunity to Fowl Cholera - (Abstract Only) - (24-Jul-98)
Bacterin-Induced Protection of Turkeys Against Fowl Cholera Following Infection with Bordetella Avium - (Peer Reviewed Journal) - (14-Jul-98)
Early Pulmonary Lesions in Turkeys Produced by Nonviable Aspergillus Fumigatus And/or Pasteurella Multocida Lipopolysaccharide - (Peer Reviewed Journal) - (07-Jul-98)
Ultrastructural Pathology of the Turkey Air Sac Membrane Exposed to Lipopolysaccharide and Non-Viable Conidia - Proceedings of the Int. SYMPOS.ON Infectious Bronchitis & Pneumovirus Infections in Poultry, 6/98, Germany - (Proceedings) - (15-Jun-98)
Susceptibility of Convalescent Turkeys to Pulmonary Aspergillosis (Research Note) - (Research Notes) - (08-Jun-98)
Abortion in a Mare Due to Mycotic Omphalitis. a Histopahtologic Study (Xv Congreso Nacional DE Investigacion Biomedica, October 20-24, 1997) - (Proceedings) - (20-Oct-97)
Pulmonary Lesions in Turkeys Produced by Pasteurella Multocida Lipopolysaccharide and Nonviable Aspergillus Fumigatus - (Proceedings) - (09-Sep-97)
Porcine Enteric Calicivirus: Development of An Animal Model for Infection by Small Round Structured Viruses in Humans - (Abstract Only) - (23-Jul-97)
Passive Immune Protection of Turkeys Against Coryza - (Peer Reviewed Journal) - (26-Jun-97)
Evaluation of the Virulence of Rhea S. Hyodysenteriae Strains for Swine - (Abstract Only) - (02-May-97)
Evaluation of Passive Immunization of Turkeys Challenged with Aspergillus Oral Presentation for Avma/aaap Meeting, Reno, Nv, July 20-24, 1997 - (Abstract Only) - (18-Apr-97)
Mycoses and Mycotoxicoses - Book Chapter in a Laboratory Manual for the Isolation and Identification of Avian Pathogens, 4th Ed. - (Book / Chapter) - (03-Mar-97)
Pulmonary Lesions in Turkeys Inoculated with Live Or Killed Aspergillus Fumigatus Conidia - (Proceedings) - (19-Jul-96)
Experimental Aspergillosis in Turkeys Treated with Dexamethasone - (Abstract Only) - (03-Jul-96)
Pathology of Acute Aspergillosis in Turkeys - (Peer Reviewed Journal) - (29-Mar-96)
Modification of a Technique for Support of Thin, Flexible Tissues for Microscopic Examination: Application to Turkey Air Sac Membranes - (Peer Reviewed Journal) - (09-Jan-96)
T-Cells Subsets in Lymph Nodes of Cattle Vaccinated with Brucella Abortus Strains Rb51 and 19 - (Abstract Only) - (06-Oct-95)
Lectin Histochemistry of the Turkey Air Sac Membrane - (Proceedings) - (06-Oct-95)
Immune Response of Mice Challenged with Brucella Abortus Strain 2308 after Oral Vaccination with Attenuated Salmonella Typhimurium Expressing Brucella Groel - (Abstract Only) - (06-Oct-95)
Modified Collection Technique for Microscopic Examination of Airsac Membranes - (Proceedings) - (04-Aug-95)
Pathology of Experimental Aspergillosis in Turkeys - (Abstract Only) - (01-May-95)
Turkey Aspergillosis - Current Research at the National Animal Disease Center - (Proceedings) - (13-Mar-95)
Last Modified: 12/17/2014
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