Projects

MEASUREMENT SYSTEMS FOR DETERMINATION OF VITAMINS IN FOODS AND DIETARY SUPPLEMENTS Appropriated (D)   Accession Number: 416459

FINGERPRINTING AND PROFILING METHODS FOR CHARACTERIZATION OF FOODS AND DIETARY SUPPLEMENTS Appropriated (D)   Accession Number: 416462

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Classification of cultivation locations of panax quinquefolius L samples using high performance liquid chromatography-electrospray ionization mass spectrometry and chemometric analysis - (Peer Reviewed Journal)

Sun, X., Chen, P., Cook, S., Jackson, G., Harnly, J.M., Harrington, P. 2012. Classification of cultivation locations of panax quinquefolius L samples using high performance liquid chromatography-electrospray ionization mass spectrometry and chemometric analysis. Analytical Chemist. 84:3628-3634.

Study of the mass spectrometric behaviors of anthocyanins in negative ionization mode and its applications for characterization of anthocyanins and non-anthocyanin polyphenols - (Peer Reviewed Journal)

Sun, J., Lin, L., Chen, P. 2012. Study of the mass spectroscopic behaviors of anthocyanins in negative ionization mode and its applications for fast differentiation of anthocyanins and non-anthocyanin polyphenols in natural products. Rapid Communications in Mass Spectrometry. 26:-1123-1132.

UHPLC-PDA-ESI/HRMS/MSn analysis of anthocyanins, flavonol glycosides, and hydroxycinnamic acid derivatives in red mustard green (Brassica juncea (L) Coss variety) - (Peer Reviewed Journal)

Lin, L., Sun, J., Chen, P., Harnly, J.M. 2011. UHPLC-PDA-ESI/HRMS/MSn analysis of anthocyanins, flavonol glycosides, and hydroxycinnamic acid derivatives in red mustard green (Brassica juncea (L) Coss variety). Journal of Agricultural and Food Chemistry. 60:544-553.

Chemical composition, and anti-proliferative and anti-inflammatory effects of the leaf and wholeplant samples of diploid and tetraploid gynostemma pentaphyllum - (Peer Reviewed Journal)

Xie, Z., Huang, H., Zhao, Y., Shi,, H., Wang, S., Wang, T.T., Chen, P., Yu, L. 2011. Chemical composition, and anti-proliferative and anti-inflammatory effects of the leaf and wholeplant samples of diploid and tetraploid gynostemma pentaphyllum . Food Chemistry. 132:125-133.

High-performance Liquid Chromatography Mass Spectrometry Analysis of Pantothenic acid (Vitamin B5) in Multivitamin Dietary Supplements - (Book / Chapter) - (01-Oct-11)

A flow-injection mass spectrometry fingerprinting method for authentication and quality assessment of Scutellaria lateriflora-based dietary supplements - (Peer Reviewed Journal)

Sun, J., Long-Ze, L., Chen, P. 2011. A flow-injection mass spectrometry fingerprinting method for authentication and quality assessment of Scutellaria lateriflora-based dietary supplements. Analytical and Bioanalytical Chemistry. 401:1577-1584.

Profiling the indole alkaloids in yohimbe bark with ultra-performance liquid chromatography coupled with ion mobility quadrupole time-of-flight mass spectrometry - (Peer Reviewed Journal)

Sun, J., Chen, P. 2011. Profiling the indole alkaloids in yohimbe bark with ultra-performance liquid chromatography coupled with ion mobility quadrupole time-of-flight mass spectrometry. Journal of Rapid Communications in Mass Spectroscopy. 25:2591-2602.

LC-PDA-EIS/MSn identification of new anthocyanins in purple radish (Raphanus sativus L. variety) - (Peer Reviewed Journal)

Lin, L., Jianghao, S., Chen, P., Harnly, J.M. 2011. LC-PDA-EIS/MSn identification of new anthocyanins in purple radish (Raphanus sativus L. variety). Journal of Agricultural food Chemistry . 59:6616-6627.

Differentiation of Panax quinquefolius grown in United States and China using LC/MS-based chromatographic fingerprinting and metabolomic approaches - (Peer Reviewed Journal)

Sun, J., Chen, P. 2011. Differentiation of Panax quinquefolius grown in United States and China using LC/MS-based chromatographic fingerprinting and metabolomic approaches. Analytical Biochemistry. 58(8):4545-4553.

Identification, quantitation, and comprehensive assessment of green, white, and pu-erh teas using UPLC/UV/MS - (Peer Reviewed Journal)

Zhao, Y., Chen, P., Lin, L., Harnly, J.M. 2011. Identification, quantitation, and comprehensive assessment of green, white, and pu-erh teas using UPLC/UV/MS. Food Chemistry. 126:1269-1277.

Discrimination among Panax species using spectral fingerprinting - (Peer Reviewed Journal)

Chen, P., Luthria, D.L., Harrington, P.B., Harnly, J.M. 2011. Discrimination among Panax species using spectral fingerprinting. Journal of the Association of Official Analytical Chemists. 94:1411-1421.

Chromatographic fingerprint analysis and rutin and quercetin compositions in the leaf and whole-plant samples of di- and tetraploid Gynostemma pentaphyllum - (Peer Reviewed Journal)

Xie, Z., Zhao, Y., Chen, P., Yu, L. 2010. Chromatographic fingerprint analysis and rutin and quercetin compositions in the leaf and whole-plant samples of di- and tetraploid Gynostemma pentaphyllum. Journal of Agricultural and Food Chemistry. 7:3042-3049.

A non-targeted approach to chemical discrimination between green tea extract-based dietary supplements and green tea leaves by LC/MS - (Peer Reviewed Journal)

Sun, J., Chen, P., Lin, L., Harnly, J.M. 2011. A non-targeted approach to chemical discrimination between green tea extract-based dietary supplements and green tea leaves by LC/MS. Journal of the Association of Official Analytical Chemists. 94:487-497.

A LC/UV/Vis method for determination of cyanocobalamin in multivitamin dietary supplements with on-line sample clean-up - (Peer Reviewed Journal)

Chen, P., Wolf, W.R., Castanheira, I., Sanches-Silva, A. 2010. A LC/UV/Vis method for determination of cyanocobalamin in multivitamin dietary supplements with on-line sample clean-up. Analytical Methods. 2:1171-1175.

Flow injection mass spectral fingerprints demonstrate chemical differences in rio red grapefruit with respect to year, harvest time, and conventional versus organic farming - (Peer Reviewed Journal)

Chen, P., Harnly, J.M., Lester, G.E. 2010. Flow injection mass spectral fingerprints demonstrate chemical differences in Rio Red grapefruit with respect to year, harvest time, and conventional versus organic farming. Journal of Agriculture and Food Chemistry. 58(8):4545-4553.

Mass spectroscopic fingerprinting method for to differentiation between Scutellaria lateriflora and the Germander (Teucrium canadens and T. chamaedrys species - (Peer Reviewed Journal)

Chen, P., Lin, L., Harnly, J.M. 2010. Mass spectroscopic fingerprinting method for differentiation between Scutellaria lateriflora and the Germander (Teucrium canadense and T. chamaedrys) species. Journal of AOAC International. 93(4):1148-1154.

Certificate of Analysis, Standard Reference Material® 1849, Infant/Adult Nutritional Formula - (Other)

Wolf, W.R., Byrdwell, W.C., Chen, P., Goldschmidt, R.J., Atkinson, R.L. 2009. Certificate of Analysis, Standard Reference Material® 1849, Infant/Adult Nutritional Formula. Available NIST Website: https://www-s.nist.gov/srmors/view_detail.cfm?srm=1849.

Single Lab Validation of a LC/UV/FLD/MS Method for Simultaneous Determination of Water-soluble Vitamins in Multi-Vitamin Dietary Supplements - (Peer Reviewed Journal)

Chen, P., Atkinson, R.L., Wolf, W.R. 2009. Single lab validation of a LC/UV/FLD/MS method for simultaneous determination of water-soluble vitamins in multi-vitamin dietary supplements. Journal of the Association of Official Analytical Chemists. 92(2):680-688.

Chromatographic fingerprint analysis of Pycnogenol® dietary supplements - (Peer Reviewed Journal)

Chen, P., Song, F., Lin, L. 2009. Chromatographic fingerprint analysis of Pycnogenol® dietary supplements. Journal of AOAC International. 92(2):624-632.

Chromatographic profiles of Ginkgo biloba leaves and selected products - (Peer Reviewed Journal)

Lin, L., Chen, P., Ozcan, M., Harnly, J.M. 2008. Chromatographic profiles of Ginkgo biloba leaves and selected products. Journal of Agricultural and Food Chemistry. http://dx.doi.org/10.1021/jf800488x.

Factors Affecting Resveratrol Content in Strawberries - (Abstract Only)

Wang, S.Y., Chen, C., Wang, C.Y., Chen, P. 2008. Factors Affecting Resveratrol Content in Strawberries. HortScience. 43(4):1230.2008

Fingerprint of Herb Product by Matrix-assisted Laser Desorption Ionization Mass Spectrometry - (Abstract Only)

Song, F., Chen, P. 2008. Fingerprint of Herb Product by Matrix-assisted Laser Desorption Ionization Mass Spectrometry. 2008 BARC Poster Day, April 23, 2008, Beltsville, MD.

Simultaneous Determination of Water Soluble Vitamins in Dietary Supplements and Fortified Foods by LC-MS - (Abstract Only)

Wolf, W.R., Goldschmidt, R.J., Chen, P. 2008. Simultaneous Determination of Water Soluble Vitamins in Dietary Supplements and Fortified Foods by LC-MS.Midwest Section of AOAC International, 2008 Annual Meeting, June 9-11 2008, Bozeman, MT.

Elucidation of the mechanism of enzymatic browning inhibition by sodium chlorite - (Peer Reviewed Journal)

He, Q., Luo, Y., Chen, P. 2008. Elucidation of the mechanism of enzymatic browning inhibition by sodium chlorite. Journal of Food Chemistry. 110(4):847-851.

Chromatographic Profiles of Ginkgo biloba Leaves and Selected Products - (Abstract Only)

Lin, L., Chen, P., Ozcan, M., Harnly, J.M. 2008. Chromatographic Profiles of Ginkgo biloba Leaves and Selected Products. Experimental Biololgy Meeting, April 5-9, 2008, San Diego, CA.

Spectral Fingerprints for Authentication and Identification of Variation in Foods and Botanical Materials - (Abstract Only)

Harnly, J.M., Luthria, D.L., Chen, P., Lin, L. 2008. Spectral Fingerprints for Authentication and Identification of Variation in Foods and Botanical Materials. Experimental Biololgy Meeting, April 5-9, 2008, San Diego, CA.

Resveratrol Content in Strawberry Fruit is Affected by Preharvest Conditions - (Peer Reviewed Journal)

Wang, S.Y., Chen, C., Wang, C.Y., Chen, P. 2007. Resveratrol Content in Strawberry Fruit is Affected by Preharvest Conditions. Journal of Agriculture and Food Chemistry. 55:8269-8274.

Simultaneous Determination of Selected B Vitamins in the NIST SRM 3280 Multivitamin/Multielement Tablets by Liquid Chromatography Isotope Dilution Mass Spectrometry - (Peer Reviewed Journal)

Chen, P., Ozcan, M., Wolf, W.R. 2007. Simultaneous determination of selected B vitamins in the NIST SRM 3280 multivitamin/multielement tablets by liquid chromatography isotope dilution mass spectrometry. Analytical and Bioanalytical Chemistry. Available: doi:10.1007/s00216-007-1430-9.

Single Laboratory Validation of a LC/UV/MS Method for Determination of Multiple Water Soluble Vitamins in Dietary Supplements (AOAC Annual Meeting, Minneapolis, MN, Sept, 2006) - (Abstract Only)

Chen, P., Wolf, W.R. 2007. Single Laboratory Validation of a LC/UV/MS Method for Determination of Multiple Water Soluble Vitamins in Dietary Supplements. AOAC Annual Meeting, September 15, 2006, Minneapolis, Minnesota.

Chromatographic fingerprints analysis for evaluation of Ginkgo Biloba products - (Peer Reviewed Journal)

Chen, P., Ozcan, M., Harnly, J.M. 2007. Chromatographic Fingerprints Analysis for Evaluation of Ginkgo Biloba Products. Analytical and Bioanalytical Chemistry. Available on-line doi: 10.1007/s00216-007-1386-9.

Simultaneous Determination of Selected B Vitamins in the NIST SRM 3280 Multivitamin/Multielement Tablets by HPLC Isotope Dilution Mass Spectrometry - (Abstract Only)

Chen, P., Ozcan, M., Wolf, W.R. 2007. Simultaneous Determination of Selected B Vitamins in the NIST SRM 3280 Multivitamin/Multielement Tablets by HPLC Isotope Dilution Mass Spectrometry. BARC Poster Day, May, 2007, Beltsville, Maryland.

Determination of Selected B-complex Vitamins in the NIST Multivitamin Reference Standard Material by Stable Isotope Dilution Mass Spectrometry (Experimental Biology, April, 2007, Washington, D.C.) - (Abstract Only)

Chen, P., Ozcan, M., Wolf, W.R. 2007. Determination of Selected B-complex Vitamins in the NIST Multivitamin Reference Standard Material by Stable Isotope Dilution Mass Spectrometry. Experimental Biology, April 25, 2007, Washington, D.C.

Determination of Ginkgolides and Flavonols in Ginkgo Biloba Products and NIST Ginkgo Reference Standard by LC/UV/MS (Experimental Biology, April, 2007, Washington, D.C.) - (Abstract Only)

Ozcan, M., Chen, P. 2007. Determination of Ginkgolides and Flavonols in Ginkgo Biloba Products and NIST Ginkgo Reference Standard by LC/UV/MS. Experimental Biology, April 25, 2007, Washington, D.C.

Validation of a LC/UV/MS Method for Determination of Multiple Water Soluble Vitamins in Dietary Supplements (Experimental Biology, April, 2007, Washington, D.C.) - (Abstract Only)

Wolf, W.R., Chen, P. 2007. Validation of a LC/UV/MS Method for Determination of Multiple Water Soluble Vitamins in Dietary Supplements. Experimental Biology, April 25, 2007, Washington, D.C.

Synthesis of safflomide and its HPLC measurement in mouse plasma after oral administration - (Peer Reviewed Journal)

Park, J.B., Chen, P. 2007. Synthesis of safflomide and its HPLC measurement in mouse plasma after oral administration. Journal of Chromatography B: Biomedical Applications. 852(1-2):398-402.

Comparison of the Terpene Lactones and Flavonols Contents in Ginkgo Biloba Commercial Samples and the NIST Standard Reference Materials Using LC/UV/MS - (Peer Reviewed Journal)

Ozcan, M., McAuley, B., and Chen, P. 2007. Comparison of the Terpene Lactones and Flavonols Contents in Ginkgo Biloba Commercial Samples and the NIST Standard Reference Materials Using LC/UV/MS. Journal of Food and Drug Analysis. 15(1):55-62

LC/UV/MS-MRM for the simultaneous determination of water-soluble vitamins in multi-vitamin dietary supplements - (Peer Reviewed Journal)

Chen, P., Wolf, W.R. 2006. LC/UV/MS-MRM for the simultaneous determination of water-soluble vitamins in multi-vitamin dietary supplements. Analytical and Bioanalytical Chemistry, 387(7):2441-2448.

Development and Validation of a High-Throughput Based on Liquid Chromatography with UV/MS Detection Method for Quantitation of Cichoric Acid in Echinacea purpurea Aerial-Based Dietary Supplements - (Peer Reviewed Journal)

Chen, P., Wolf, W.R. 2006. Development and Validation of a High-Throughput Based on Liquid Chromatography with UV/MS Detection Method for Quantitation of Cichoric Acid in Echinacea purpurea Aerial-Based Dietary Supplements. Journal of Association of Official Analytical Chemists International. 89:(3)612-618.

DEVELOPMENT OF AN EFFICIENT, SCALABLE, ALDOLASE-CATALYZED PROCESS FOR ENANTIOSELECTIVE SYNTHESIS OF STATIN INTERMEDIATES - (Proceedings)

Greenberg, W.A., Varvak, A., Hanson, S.R., Wong, K., Huang, H., Chen, P., Burk, M.J. 2004. Development of an efficient, scalable, aldolase-catalyzed process for enantioselective synthesis of statin intermediates. #89158. 101(16):5788-5793.

CREATION OF A PRODUCTIVE, HIGHLY ENANTIOSELECTIVE NITRILASE THROUGH GENE SITE SATURATION MUTAGENESIS (GSSM) - (Proceedings)

Greenberg, W.A., Varvak, A., Hanson, S.R., Wong, K., Huang, H., Chen, P., Burk, M.J. 2004. Creation of a productive, highly enantioselective nitrilase through gene site saturation mutagenesis (GSSM). Proceedings of the National Academy of Sciences. 101(16):5788-5793.