Projects

MOLECULAR ANALYSIS OF SALMONELLA VIRULENCE, ANTIBIOTIC RESISTANCE, AND HOST RESPONSE Appropriated (D)   Accession Number: 421023

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Profiling the gastrointestinal microbiota in response to Salmonella: low versus high Salmonella shedding in the natural porcine host - (Peer Reviewed Journal)

Bearson, S.M., Allen, H.K., Bearson, B.L., Looft, T.P., Brunelle, B.W., Kich, J.D., Christopher, T.K., Bayles, D.O., Alt, D.P., Levine, U.Y., Stanton, T.B. 2013. Profiling the gastrointestinal microbiota in response to Salmonella: low versus high Salmonella shedding in the natural porcine host. Infection, Genetics and Evolution. Available: http://authors.elsevier.com/sd/article/S1567134813000956.

Evaluation of the impact of quorum sensing transcriptional regulator SdiA on long-term persistence and fecal shedding of Escherichia coli O157:H7 in weaned calves - (Peer Reviewed Journal)

Sharma, V.K., Bearson, S.M. 2013. Evaluation of the impact of quorum sensing transcriptional regulator SdiA on long-term persistence and fecal shedding of Escherichia coli O157:H7 in weaned calves. Microbial Pathogenesis. 57:21-26.

Tetracycline can induce the expression of invasion factors in multidrug-resistant Salmonella during early-log phase - (Abstract Only)

Brunelle, B.W., Bearson, S.M., Bearson, B.L. 2012. Tetracycline can induce the expression of invasion factors in multidrug-resistant Salmonella during early-log phase [abstract]. American Society for Microbiology General Meeting, June 16-19, 2012, San Francisco, California. Paper No. 1606.

Profiling the gastrointestinal microbiota in response to Salmonella: low versus high Salmonella shedding in the porcine host - (Abstract Only)

Bearson, S.M., Allen, H.K., Bearson, B.L., Looft, T.P., Brunelle, B.W., Kich, J.D., Bayles, D.O., Alt, D.P., Levine, U.Y., Stanton, T.B. 2012. Profiling the gastrointestinal microbiota in response to Salmonella: low versus high Salmonella shedding in the porcine host [abstract]. American Society for Microbiology General Meeting, June 16-19, 2012, San Francisco, California. p. 3150.

Phenotype microarray analysis of a Salmonella enterica serovar Typhimurium qseC mutant compared to a qseBC mutant and the wild-type strain - (Abstract Only)

Bearson, B.L., Bearson, S.M.D., Lee, I.S. 2012. Phenotype microarray analysis of a Salmonella enterica serovar Typhimurium qseC mutant compared to a qseBC mutant and the wild-type strain [abstract]. In: Abstracts of the 112th General Meeting of the American Society for Microbiology, June 16-19, 2012, San Francisco, California. p. 228.

Mitsuokella jalaludinii inhibits growth of Salmonella enterica serovar Typhimurium - (Peer Reviewed Journal)

Levine, U.Y., Bearson, S.M., Stanton, T.B. 2012. Mitsuokella jalaludinii inhibits growth of Salmonella enterica serovar Typhimurium. Veterinary Microbiology. 159(1-2):115-122.

Correlating levels of type III secretion and secreted proteins with fecal shedding of Escherichia coli O157:H7 in cattle - (Peer Reviewed Journal)

Sharma, V.K., Sacco, R.E., Kunkle, R.A., Bearson, S.M., Palmquist, D.E. 2012. Correlating levels of type III secretion and secreted proteins with fecal shedding of Escherichia coli O157:H7 in cattle. Infection and Immunity. 80(4):1333-1342.

Distinct peripheral blood RNA responses to Salmonella in pigs differing in Salmonella shedding levels: intersection of IFNG, TLR and miRNA pathways - (Peer Reviewed Journal)

Huang, T., Uthe, J.J., Bearson, S.M., Demirkale, C.Y., Nettleton, D., Knetter, S.M., Christian, C.M., Ramer-Tait, A.E., Wannemuehler, M.J., Tuggle, C.K. 2011. Distinct peripheral blood RNA responses to Salmonella in pigs differing in Salmonella shedding levels: intersection of IFNG, TLR and miRNA pathways. PLoS One [serial online]. 6(12). Available: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0028768.

Enterohemorrhagic Escherichia coli O157:H7 requires quorum sensing transcriptional regulators QseA and SdiA for colonization and persistence in the bovine intestinal tract - (Abstract Only)

Sharma, V.K., Bearson, S.M., Thacker, T.C. 2011. Enterohemorrhagic Escherichia coli O157:H7 requires quorum sensing transcriptional regulators QseA and SdiA for colonization and persistence in the bovine intestinal tract [abstract]. 71st Annual Meeting of the North Central Branch of the American Society for Microbiology. October 7-8, 2011, Des Moines, Iowa. 59:147.

Mitsuokella jalaludinii inhibits growth of Salmonella enterica serovar Typhimurium - (Abstract Only)

Levine, U.Y., Bearson, S.M., Stanton, T.B. 2011. Mitsuokella jalaludinii inhibits growth of Salmonella enterica serovar Typhimurium [abstract]. 71st Annual Meeting of the North Central Branch of the American Society for Microbiology. October 7-8, 2011, Des Moines, Iowa. 60:147.

A mutation in the pnp gene encoding polynucleotide phosphorylase attenuates virulence of Salmonella enterica serovar typhimurium in swine - (Abstract Only)

Bearson, S.M., Bearson, B.L., Lee, I. 2011. A mutation in the pnp gene encoding polynucleotide phosphorylase attenuates virulence of Salmonella enterica serovar typhimurium in swine [abstract]. 111th General Meeting American Society for Microbiology. p.1487.

Serological response of swine to an attenuated Salmonella enterica serovar Typhimurium strain that reduces gastrointestinal colonization, fecal shedding and disease due to virulent Salmonella Typhimurium - (Abstract Only)

Bearson, B.L., Bearson, S.M. 2011. Serological response of swine to an attenuated Salmonella enterica serovar Typhimurium strain that reduces gastrointestinal colonization, fecal shedding and disease due to virulent Salmonella Typhimurium. 9th International Conference on the Epidemiology and Control of biological, chemical and physical hazards in pigs and pork, June 19-22, 2011, Maastricht, Netherlands. p. 228.

Use of bioinformatic SNP predictions in differentially expressed genes to find SNPs associated with Salmonella colonization in swine - (Peer Reviewed Journal)

Uthe, J.J., Qu, L., Couture, O., Bearson, S.M., O'Connor, A., Mckean, J., Rodriguez, T.Y., Dekkers, J.C., Nettleton, D., Tuggle, C.K. 2011. Use of bioinformatic SNP predictions in differentially expressed genes to find SNPs associated with Salmonella colonization in swine. Journal of Animal Breeding and Genetics. 128(5):354-365.

Salmonella enterica serovar Typhimurium DT104 invasion is not enhanced by sub-inhibitory concentrations of the antibiotic florfenicol - (Peer Reviewed Journal)

Brunelle, B.W., Bearson, S.M., Bearson, B.L. 2011. Salmonella enterica serovar Typhimurium DT104 invasion is not enhanced by sub-inhibitory concentrations of the antibiotic florfenicol. Journal of Veterinary Science and Technology. 2:104. Available: http://omicsonline.org/2157-7579/2157-7579-2-104.php.

An attenuated Salmonella enterica serovar Typhimurium strain reduces disease severity, fecal shedding, and gastrointestinal colonization in swine due to virulent S. Typhimurium challenge - (Abstract Only)

Bearson, B.L., Bearson, S.M. 2011. An attenuated Salmonella enterica serovar Typhimurium strain reduces disease severity, fecal shedding, and gastrointestinal colonization in swine due to virulent S. Typhimurium challenge [abstract]. In: Abstracts of the 111th General Meeting of the American Society for Microbiology, May 21-24, 2011, New Orleans, Louisana. p. 179.

Host specific differences alter the requirement for certain Salmonella genes during swine colonization - (Review Article)

Bearson, B.L., Bearson, S.M. 2011. Host specific differences alter the requirement for certain Salmonella genes during swine colonization. Veterinary Microbiology. 150:215-219.

A Mutation in the PoxA Gene of Salmonella enterica Serovar Typhimurium Results in Altered Protein Production, Elevated Susceptibility to Environmental Challenges, and Decreased Swine Colonization - (Peer Reviewed Journal)

Bearson, S.M., Bearson, B.L., Brunelle, B.W., Sharma, V.K., Lee, I. 2011. A mutation in the poxA gene of Salmonella enterica serovar Typhimurium results in altered protein production, elevated susceptibility to environmental challenges, and decreased swine colonization. Foodborne Pathogens and Disease. 8(6):725-732.

Sub-Inhibitory Concentrations of the Antibiotic Florfenicol Reduces Invasion in Isolates of Multi-Drug Resistant Salmonella Typhimurium DT104 - (Abstract Only)

Brunelle, B.W., Bearson, S.M., Bearson, B.L. 2010. Sub-Inhibitory Concentrations of the Antibiotic Florfenicol Reduces Invasion in Isolates of Multi-Drug Resistant Salmonella Typhimurium DT104 [abstract]. Conference of Research Workers in Animal Diseases. p. 26.

Integrating comparative expression profiling data with association of SNPs to Salmonella shedding for improved food safety and porcine disease resistance - (Peer Reviewed Journal)

Uthe, J.J., Bearson, S.M., Qu, L., Dekkers, J.C., Nettleton, D., Y Rodriguez, T., O'Connor, A., Mckean, J., Tuggle, C.K. 2011. Integrating comparative expression profiling data with association of SNPs to Salmonella shedding for improved food safety and porcine disease resistance. Animal Genetics. 42(5):521-534.

Methods for transcriptomic analyses of the porcine host immune response: application to Salmonella infection using microarrays - (Review Article)

Tuggle, C.K., Bearson, S.M., Uthe, J.J., Huang, T.H., Qu, L., Couture, O.P., Wang, Y., Kuhar, D.J., Lunney, J.K., Nettleton, D., Honavar, V., Dekkers, J.C. 2010. Methods for transcriptomic analyses of the porcine host immune response: application to Salmonella infection using microarrays. Veterinary Immunology and Immunopathology. 138(4):280-291.

The Salmonella enterica serovar Typhimurium QseB Response Regulator Negatively Regulates Bacterial Motility and Swine Colonization in the Absence of the QseC Sensor Kinase - (Peer Reviewed Journal)

Bearson, B.L., Bearson, S.M., Lee, I., Brunelle, B.W. 2010. The Salmonella enterica serovar Typhimurium QseB Response Regulator Negatively Regulates Bacterial Motility and Swine Colonization in the Absence of the QseC Sensor Kinase. Microbial Pathogenesis. 48:214-219.

Evaluation of the Effects of SDIA, a LUXR Homologue, on Adherence and Motility of Escherichia coli O157:H7 - (Peer Reviewed Journal)

Sharma, V.K., Bearson, S.M., Bearson, B.L. 2010. Evaluation of the Effects of SDIA, a LUXR Homologue, on Adherence and Motility of Escherichia coli O157:H7. Microbiology. 156(5):1303-1312.

A Mutation in the Putative Lysl-tRNA Synthetase Gene, PoxR of Salmonella enterica Serovar Typhimurium Results in Altered Protein Production, Elevated Susceptibility to Environmental Challenges and Decreased Swine Colonization - (Abstract Only)

Bearson, S.M., Bearson, B.L. A Mutation in the Putative Lysl-tRNA Synthetase Gene, PoxR of Salmonella enterica Serovar Typhimurium Results in Altered Protein Production, Elevated Susceptibility to Environmental Challenges and Decreased Swine Colonization [abstract]. American Society for Microbiology Conference on Salmonella: Biology, Pathogenesis and Prevention. p.115.

Upregulation of STM3175 Decreases Bacterial Motility and Swine Colonization in a qseC (preB) Mutant of Salmonella enterica serovar Typhimurium - (Abstract Only)

Bearson, B.L., Bearson, S.M., Lee, I. 2009. Upregulation of STM3175 Decreases Bacterial Motility and Swine Colonization in a qseC (preB) Mutant of Salmonella enterica serovar Typhimurium. ASM Conference on Salmonella: Biology, Pathogenesis & Prevention, October 5-9, 2009, Aix-en-Provence, France. p. 41.

Differences in Pathogenesis for Salmonella enterica serovar Typhimurium in the Mouse Versus the Swine Model Identify Bacterial Gene Products Required for Systemic but not Gastrointestinal Disease - (Abstract Only)

Bearson, B.L., Bearson, S.M. 2009. Differences in Pathogenesis for Salmonella enterica serovar Typhimurium in the Mouse Versus the Swine Model Identify Bacterial Gene Products Required for Systemic but not Gastrointestinal Disease. International Symposium on the Epidemiology and Control of Foodborne Pathogens in Pork, September 30-October 2, 2009, Quebec City, Canada. p. 88.

THE POXR GENE OF SALMONELLA ENTERICA SEROVAR TYPHIMURIUM IS INVOLVED IN STRESS SURVIVAL AND SWINE COLONIZATION - (Abstract Only)

Bearson, S.M., Bearson, B.L., Lee, I. 2009. The Poxr Gene of Salmonella Enterica Serovar Typhimurium is Involved in Stress Survival and Swine Colonization [abstract]. American Society for Microbiology Meeting. p. 619.

The QseB Response Regulator is Required for Decreased Bacterial Motility and Swine Colonization in a QseC Mutant of Salmonella enterica serovar Typhimurium - (Abstract Only)

Bearson, B.L., Bearson, S.M., Lee, I., Brunelle, B.W. 2009. The QseB Response Regulator is Required for Decreased Bacterial Motility and Swine Colonization in a QseC Mutant of Salmonella enterica serovar Typhimurium [abstract]. In: Abstracts of the 109th General Meeting of the American Society for Microbiology, May 17-21, 2009, Philadelphia, Pennsylvania. p. 611.

EVALUATING THE ROLE OF SDIA AND HHA IN ENHANCED ADHERENCE OF A SDIA HHA DOUBLE MUTANT OF ENTEROHEMORRHAGIC ESCHERICHIA COLI O157:H7 - (Abstract Only)

Sharma, V.K., Bearson, S.M., Bearson, B.L. 2009. Evaluating the Role of SDIA and HHA in Enhanced Adherence of a SDIA HHA Double Mutant of Enterohemorrhagic Escherichia coli O157:H7 [abstract]. American Society for Microbiology Meeting. Paper No. B108.

Characterization of Fecal Microbiota from a Salmonella Endemic Cattle Herd as Determined by Oligonucleotide Fingerprinting of RDNA Genes - (Peer Reviewed Journal)

Patton, T.G., Scupham, A.J., Bearson, S.M., Carlson, S.A. 2009. Characterization of Fecal Microbiota from a Salmonella Endemic Cattle Herd as Determined by Oligonucleotide Fingerprinting of rDNA Genes. Veterinary Microbiology. 136(3-4):285-292.

Correlating Blood Immune Parameters and a CCT7 Genetic Variant with the Shedding of Salmonella enterica Serovar Typhimurium in Swine - (Peer Reviewed Journal)

Uthe, J.J., Wang, Y.F., Long, Q., Nettleton, D., Tuggle, C.K., Bearson, S.M. 2009. Correlating Blood Immune Parameters and a CCT7 Genetic Variant with the Shedding of Salmonella enterica Serovar Typhimurium in Swine. Veterinary Microbiology. 135(3-4):384-388.

ANALYSIS OF PORCINE TRANSCRIPTIONAL RESPONSE TO SALMONELLA ENTERICA SEROVAR CHOLERAESUIS SUGGESTS NOVEL TARGETS OF NFKAPPAB ARE ACTIVATED IN THE MESENTERIC LYMPH NODE - (Peer Reviewed Journal)

Wang, Y., Couture, O.P., Qu, L., Uthe, J., Bearson, S.M., Kuhar, D.J., Lunney, J.K., Nettleton, D., Dekkers, J.C., Tuggle, C.K. 2008. Analysis of Porcine Transcriptional Response to Salmonella enterica Serovar Choleraesuis Suggests Novel Targets of NFkappaB are Activated in the Mesenteric Lymph Node. Biomed Central (BMC) Genomics. 9(437). Available: http://biomedcentral.com/1471-2164/9/437.

Iron regulated genes of Salmonella enterica serovar Typhimurium in response to norepinephrine and the requirement of fepCDG for norepinephrine-enhanced growth - (Peer Reviewed Journal)

Bearson, B.L., Bearson, S.M., Uthe, J., Houghton, J., Dowd, S.E., Lee, I., Toscano, M.J., Lay Jr, D.C. 2008. Iron regulated genes of Salmonella enterica serovar Typhimurium in response to norepinephrine and the requirement of fepCDG for norepinephrine-enhanced growth. Microbes and Infection. 10(7):807-816.

Traversing the Swine Gastrointestinal Tract: Salmonella Survival and Pathogenesis - (Book / Chapter)

Bearson, S.M., Bearson, B.L. 2010. Traversing the Swine Gastrointestinal Tract: Salmonella Survival and Pathogenesis. In: Ricke, S.C., Jones, F.T., editors. Perspectives on Food-Safety Issues of Animal-Derived Foods. Fayetteville, AR: University of Arkansas Press. p. 35-48.

EVALUATION OF THE EFFECTS OF QUORUM-SENSING SIGNALING PATHWAYS ON THE EXPRESSION OF HHA AND OTHER REGULATORS OF LEE EXPRESSION IN ESCHERICHIA COLI O157:H7 - (Abstract Only)

Sharma, V.K., Bearson, S.M., Bearson, B.L. 2008. Evaluation of the effects of quorum-sensing signaling pathways on the expression of hha and other regulators of LEE expression in Escherichia coli O157:H7 [abstract]. American Society for Microbiology Meeting. Paper No. H036.

Computational Integration of Structural and Functional Genomics Data Across Species to Develop Information on Porcine Inflammatory Gene Regulatory Pathway - (Proceedings)

Tuggle, C.K., Wang, Y.F., Couture, O.P., Qu, L., Uthe, J.J., Kuhar, D.J., Lunney, J.K., Nettleton, D., Dekkers, J.C., Bearson, S.M. 2008. Computational Integration of Structural and Functional Genomics Data Across Species to Develop Information on Porcine Inflammatory Gene Regulatory Pathway. In: Animal Genomics for Animal Health M.-H. Pinard, C. Gay, P.-P. Pastoret, B. Dodet (Eds); In the series Developments in Biologicals (Karger, Basel). 132:105-114.

The role of QseC quorum-sensing sensor kinase in colonization and norepinephrine-enhanced motility of Salmonella enterica serovar Typhirmurium - (Peer Reviewed Journal)

Bearson, B.L., Bearson, S.M. 2008. The role of QseC quorum-sensing sensor kinase in colonization and norepinephrine-enhanced motility of Salmonella enterica serovar Typhirmurium. Microbial Pathogenesis. 44:271-278.

Computational Integration Of Structural And Functional Genomics Data Across Species To Develop Porcine Inflammatory Gene Regulatory Pathway Information - (Abstract Only)

Tuggle, C.K., Wang, Y.F., Couture, O.P., Qu, L., Uthe, J.J., Kuhar, D.J., Lunney, J.K., Nettleton, D., Dekkers, J.C., Bearson, S.M., Bearson,, S.D. 2007. Computational Integration Of Structural And Functional Genomics Data Across Species To Develop Porcine Inflammatory Gene Regulatory Pathway Information. Proceedings International Symposium on Animal Genomics for Animal Health,OIE, Paris, France, October 2007.p 33.

The Role of the QseC Sensor Kinase in Salmonella enterica serovar Typhimurium Quorum Sensing and Swine Colonization - (Abstract Only)

Bearson, B.L., Bearson, S.M. 2007. The role of the QseC sensor kinase in Salmonella enterica serovar Typhimurium quorum sensing and swine colonization [abstract]. In: Proceedings of 3rd American Society for Microbiology Conference on Cell-Cell Communication in Bacteria, October 7-10, 2007, Austin, Texas. p. 34, 20A.

Comparative immune responses of pigs to infection with Salmonella enterica serovars of food safety (Typhimurium) and animal health (Choleraesuis) importance - (Abstract Only)

Lunney, J.K., Bearson, S.M., Wang, Y.F., Uthe, J.J., Qu, K., Couture, O.P., Zhao, S.H., Kuhar, D.J., Nettleton, D., Dekkers, J.C., Tuggle, C.K. 2007. Comparative immune responses of pigs to infection with Salmonella enterica serovars of food safety (Typhimurium) and animal health (Choleraesuis)importance. Proceedings 8th Intl Veterinary Immunology Symposium, Ouro Preto, Brazil. p. 49-50.

A SINGLE NUCLEOTIDE POLYMORPHISM IN THE PORCINE CCT7 GENE CORRELATES WITH SALMONELLA SHEDDING IN SWINE - (Abstract Only)

Uthe, J.J., Bearson, S.M., Wang, Y., Qu, L., Dekkers, J., Nettleton, D., Tuggle, C. 2007. A single nucleotide polymorphism in the porcine CCT7 gene correlates with Salmonella shedding in swine [abstract]. American Society for Microbiology. Paper No. 156.

GLOBAL TRANSCRIPTIONAL RESPONSE OF PORCINE MESENTERIC LYMPH NODES TO SALMONELLA ENTERICA SEROVAR TYPHIMURIUM - (Peer Reviewed Journal)

Wang, Y.F., Qu, L., Uthe, J.J., Bearson, S.M., Kuhar, D.J., Lunney, J.K., Couture, O.P., Nettleton, D., Dekkers, J.C., Tuggle, C.K. 2007. Global transcriptional response of porcine mesenteric lymph nodes to Salmonella enterica serovar Typhimurium. Genomics. 90(1):72-84.

ASSOCIATIONS OF THE PORCINE IMMUNE RESPONSE AND GENETIC POLYMORPHISMS WITH THE SHEDDING OF SALMONELLA ENTERICA SEROVAR TYPHIMURIUM - (Proceedings)

Bearson, S.M., Uthe, J.J., Wang, Y., Qu, L., Dekkers, J., Nettleton, D., Tuggle, C. 2007. Associations of the porcine immune response and genetic polymorphisms with the shedding of Salmonella enterica serovar Typhimurium. In: Proceedings of the 7th International Symposium on the epidemiology and control of foodborne pathogens in pork, May 9-11, 2007, Vernona, Italy. p. 413-417.

The QseBC Quorum Sensing System is Involved in Salmonella enterica serovar Typhimurium Colonization of the Swine Gastrointestinal Tract - (Proceedings)

Bearson, B.L., Bearson, S.M. 2007. The QseBC Quorum Sensing System is Involved in Salmonella enterica serovar Typhimurium Colonization of the Swine Gastrointestinal Tract. In: Proceedings of the 7th International Symposium on the Epidemiology and Control of Foodborne Pathogens in Pork, May 9-11, 2007, Verona, Italy. p. 409-412.

PORCINE DIFFERENTIAL GENE EXPRESSION IN RESPONSE TO SALMONELLA ENTERICA SEROVARS CHOLERAESUIS AND TYPHIMURIUM - (Peer Reviewed Journal)

Uthe, J.J., Bearson, S.M., Royaee, A.R., Lunney, J.K., Stabel, T.J., Zhao, S., Tuggle, C.K. 2007. Porcine differential gene expression in response to Salmonella enterica serovars Choleraesuis and Typhimurium. Molecular Immunology. 44(11):2900-2914.

Cultivation of Salmonella enterica serovar Typhimurium in a norepinephrine-containing medium alters in vivo tissue prevalence in swine - (Peer Reviewed Journal)

Toscano, M.J., Stabel, T.J., Bearson, S.M., Bearson, B.L., Lay Jr, D.C. 2007. Cultivation of Salmonella enterica seovar Typhimurium in a norepinephrine-containing medium alters in vivo tissue prevalence in swine. Journal of Experimental Animal Science. 43(4):329-338.

Cultivation of Salmonella enterica serovar Typhimurium in a norepinephrine-containing medium alters in vivo tissue prevalence in swine - (Peer Reviewed Journal)

Toscano, M.J., Stabel, T.J., Bearson, S.M., Bearson, B.L., Lay Jr, D.C. 2007. Cultivation of Salmonella enterica serovar Typhimurium in a norepinephrine-containing medium alters in vivo tissue prevalence in swine. Journal of Experimental Animal Science. 43(4):329-338.

AN UPDATE OF RESEARCH AT THE NATIONAL ANIMAL DISEASE CENTER - (Other)

Bearson, S.M., Gerbyshak, H.A., Harbaugh, E., Hurd, H.S., Jones, J., Muraoka, W.T., Rostagno, M.H., Scupham, A.J., Wesley, I.V. 2006. An update of research at the National Animal Disease Center. Available: http://www.ars.usda.gov/research/programs/programs.htm?np_code=108&docid=13576.

SENSITIVITY OF SALMONELLA ENTERICA SEROVAR TYPHIMURIUM TO LACTIC ACID PRESENT IN PORCINE STOMACH CONTENTS - (Abstract Only)

Bearson, B.L., Bearson, S.M., Rasmussen, M.A. 2006. Sensitivity of Salmonella enterica serovar Typhimurium to lactic acid present in porcine stomach contents [abstract]. American Society for Microbiology. p.639.

GENETIC ANALYSIS OF THE SURVIVAL OF SALMONELLA ENTERICA SEROVAR TYPHIMURIUM WITHIN RUMEN PROTOZOA - (Proceedings)

Bearson, S.M., Bearson, B.L., Rasmussen, M.A. 2006. Genetic analysis of the survival of Salmonella enterica serovar Typhimurium within rumen protozoa. Proceedings of 13S International Symposium Salmonella and Salmonellosis. p.279-282.

LACK OF A STRONG NFKB-DEPENDENT TRANSCRIPTIONAL RESPONSE DURING INFECTION WITH SALMONELLA ENTERICA SEROVAR TYPHIMURIUM AS COMPARED TO THAT OBSERVED IN S. CHOLERAESUIS INFECTION - (Abstract Only)

Wang, Y.F., Uthe, J.J., Bearson, S.M., Kuhar, D.J., Lunney, J.K., Qu, L., Nettleton, D., Tuggle, C.K. Lack of a strong nfkb-dependent transcriptional response during infection with Salmonella enterica serovar Typhimurium as compared to that observed in Salmonella Choleraesuis infection [abstract]. International Society of Animal Genetics. p. 264.

IDENTIFICATION OF SALMONELLA ENTERICA SEROVAR TYPHIMURIUM GENES IMPORTANT FOR SURVIVAL IN THE SWINE GASTRIC ENVIRONMENT - (Peer Reviewed Journal)

Bearson, S.M., Bearson, B.L., Rasmussen, M.A. 2006. Identification of Salmonella enterica serovar Typhimurium genes important for survival in the swine gastric environment. Applied and Environmental Microbiology. 72(4):2829-2836.

GENE EXPRESSION PROFILING IN SALMONELLA CHOLERAESUIS INFECTED PORCINE LUNG USING A LONG OLIGONUCLEOTIDE MICROARRAY - (Peer Reviewed Journal)

Zhao, S., Recknor, J., Kuhar, D.J., Nettleton, D., Lunney, J.K., Orley, S., Uthe, J., Bearson, S.M., Dawson, H., Tuggle, C.K. 2006. Gene expression profiling in salmonella choleraesuis infected porcine lung using a long oligonucleotide microarray. Mammalian Genome.

TRANSCIPTIONAL SUPPRESSION OF SPECIFIC PORCINE IMMUNE PATHWAYS DURING INFECTION WITH SALMONELLA ENTERICA SEROTYPE TYPHIMURIUM COMPARED TO CHOLERAESUIS - (Abstract Only)

Wang, Y.F., Uthe, J.J., Bearson, S.M., Kuhar, D.J., Lunney, J.K., Qu, L., Couture, O., Nettleton, D., Tuggle, C.K. 2006. Transciptional suppression of specific porcine immune pathways during infection with Salmonella enterica serotype Typhimurium compared to Choleraesuis [abstract]. International Plant and Animal Genome IX Conference. p. W242.

USING A FIRST-GENERATION PORCINE AFFYMETRIX GENECHIP® TO INVESTIGATE THE FUNCTIONAL GENOMICS OF IMMUNE RESPONSE AND REPRODUCTIVE BIOLOGY - (Abstract Only)

Tuggle, C.K., Qu, L., Wang, Y., Couture, O., Nettleton, D., Dekkers, J., Zhao, S., Uthe, J.J., Bearson, S.M. 2006. Using a first-generation Porcine Affymetrix GeneChip® to investigate the functional genomics of immune response and reproductive biology [abstract]. International Plant and Animal Genome IX Conference. p.W407

ANALYSIS OF PORCINE DIFFERENTIAL GENE EXPRESSION FOLLOWING CHALLENGE WITH SALMONELLA ENTERICA SEROTYPE CHOLERAESUIS USING SUPPRESSION SUBTRACTIVE HYBRIDIZATION - (Peer Reviewed Journal)

Uthe, J.J., Stabel, T.J., Zhao, S., Tuggle, C.K., Bearson, S.M. 2006. Analysis of porcine differential gene expression following challenge with Salmonella enterica serotype Choleraesuis using suppression subtractive hybridization. Veterinary Microbiology. 114(1-2):60-71.

IDENTIFICATION OF DIFFERENTIALLY EXPRESSED GENES IN RESPONSE TO INFECTION TO HOST-SPECIFIC AND HOST-GENERALIST SALMONELLA ENTERICA SEROTYPES IN PIGS - (Abstract Only)

Wang, Y., Uthe, J.J., Bearson, S.M., Qu, L., Nettleton, D., Tuggle, C.K. 2005. Identification of differentially expressed genes in response to infection to host-specific and host-generalist Salmonella enterica serotypes in pigs [abstract]. Integration of Structural and Functional Genomics Symposium. p. 23.

ANALYSIS OF THE SWINE TRANSCRIPTIONAL RESPONSE TO SALMONELLA ENTERICA SEROVAR TYPHIMURIUM - (Abstract Only)

Uthe, J.J., Royaee, A., Lunney, J.K., Stabel, T.J., Zhao, S., Tuggle, C.K., Bearson, S.M. 2005. Analysis of the swine transcriptional response to Salmonella enterica serovar Typhimurium [abstract]. North Central Branch-American Society for Microbiology. p. 69.

INTEGRATION OF STRUCTURAL AND FUNCTIONAL GENOMICS - (Abstract Only)

Zhao, S., Kuhar, D.J., Recknor, J., Lunney, J.K., Nettleton, D., Dawson, H.D., Orley, S., Uthe, J., Bearson, S.M., Tuggle, C.K. 2005. Integration of structural and functional genomies. Proceedings of Integration of Structural and Functional Genomics Sympoisium 22-25 September 2005, p. 39.

ASSIGNMENT OF THE SCAVENGER RECEPTOR CLASS B, MEMBER 2 GENE (SCARB2) TO PORCINE CHROMOSOME 8Q11-Q12 BY SOMATIC CELL AND RADIATION HYBRID PANEL MAPPING - (Peer Reviewed Journal)

Kim, J.W., Zhao, S.H., Uthe, J.J., Bearson, S.M., Tuggle, C.K. 2006. Assignment of the scavenger receptor class B, member 2 gene (SCARB2) to porcine chromosome 8q11-->q12 by somatic cell and radiation hybrid panel mapping. Cytogenetics and Genome Research. 112(3-4):342H.

THE TRANSCRIPTIONAL RESPONSE TO SALMONELLA INFECTION IN SWINE - (Proceedings)

Bearson, S.M., Uthe, J.J., Royaee, A.R., Lunney, J.K., Zhao, S., Kim, J., Tuggle, C.K. 2005. The transcriptional response to Salmonella infection in swine. Safepork 2005. p. 68-71.

MONITORING THE SHEDDING OF SALMONELLA ENTERICA SEROVAR TYPHIMURIUM FROM EXPERIMENTALLY INFECTED SWINE - (Abstract Only)

Schatz, A.J., Morrison, E., Bearson, S.M. 2005. Monitoring the shedding of Salmonella enterica serovar Typhimurium from experimentally infected swine [abstract]. Annual Merck Merial Veterinary Scholars Symposium. p.48

DIFFERENTIAL EXPRESSION OF PORCINE CYTOSKELETON GENES DURING INFECTION WITH SALMONELLA ENTERICA SEROTYPE CHOLERAESUIS - (Abstract Only)

Uthe, J.J., Zhao, S., Tuggle, C.K., Bearson, S.M. 2005. Differential expression of porcine cytoskeleton genes during infection with Salmonella enterica serotype Choleraesuis [abstract]. Genetics of Animal Health. p. 128.

PHYSICAL MAPPING OF EIGHT PIG GENES WHOSE EXPRESSION LEVEL IS ACUTELY AFFECTED BY SALMONELLA CHALLENGE - (Peer Reviewed Journal)

Kim, J.W., Zhao, S.H., Uthe, J.J., Bearson, S.M., Tuggle, C.K. 2005. Physical mapping of eight pig genes whose expression level is acutely affected by Salmonella challenge. Animal Genetics. 36(4):359-62.

DNA MICROARRAY ANALYSIS OF SALMONELLA ENTERICA SEROVAR TYPHIMURIUM DURING EXPOSURE TO NOREPINEPHRINE - (Abstract Only)

Bearson, B.L., Bearson, S.M., Uthe, J.J., Toscano, M.J., Lay Jr, D.C. 2005. DNA microarray analysis of Salmonella enterica serovar Typhimurium during exposure to norepinephrine [abstract]. American Society for Microbiology. p. 361.

DIFFERENCES IN THE SWINE RESPONSE TO INFECTION WITH SALMONELLA ENTERICA SEROVARS CHOLERAESUIS AND TYPHIMURIUM - (Abstract Only)

Uthe, J.J., Royaee, A.R., Lunney, J.K., Stabel, T.J., Zhao, S., Tuggle, C.K., Bearson, S.M. 2005. Differences in the swine response to infection with Salmonella enterica serovars Choleraesuis and Typhimurium [abstract]. American Society for Microbiology. p. 614.

MYCOPLASMA GALLISEPTICUM: CURRENT AND DEVELOPING MEANS TO CONTROL THE AVIAN PATHOGEN - (Peer Reviewed Journal)

Evans, J.D., Leigh, S.A., Branton, S.L., Collier, S.D., Pharr, G.T., Bearson, S.M. 2005. Mycoplasma gallisepticum: current and developing means to control the avian pathogen. Journal of Applied Poultry Research. 14:757-763.

PHYSICAL MAPPING OF FIVE PIG GENES WHOSE EXPRESSION LEVEL IS ACUTELY AFFECTED BY SALMONELLA CHALLENGE - (Abstract Only)

Kim, J.W., Zhao, S.H., Uthe, J.J., Bearson, S.M., Tuggle, C.K. 2005. Physical mapping of five pig genes whose expression level is acutely affected by Salmonella challenge [abstract]. Joint Abstracts of the American Dairy Science and Society of Animal Science Midwest Meeting. p. 9.

IDENTIFICATION OF DIFFERENTIALLY EXPRESSED GENES IN PORCINE LUNG TISSUE DURING SALMONELLA ENTERICA SEROVAR CHOLERAESUIS INFECTION USING A 13,000 SWINE GENE OLIGO MICROARRAY - (Abstract Only)

Zhao, S.H., Recknor, J., Nettleton, D., Lunney, J.K., Uthe, J.J., Bearson, S.M., Tuggle, C.K. 2005. Identification of differentially expressed genes in porcine lung tissue during Salmonella enterica serovar Choleraesuis infection using a 13,000 swine gene oligo microarray [abstract]. Plant and Animal Genome XIII Conference. Abstract No. P568.

A SELF-PROPELLED, CONSTANT SPEED SPRAY VACCINATOR FOR COMMERCIAL LAYER CHICKENS - (Peer Reviewed Journal)

Branton, S.L., Lott, B.D., Evans, J.D., Collier, S.D., Roush, W.B., Bearson, S.M., Bearson, B.L., Pharr, G.T. 2005. A self-propelled, constant speed spray vaccinator for commercial layer chickens. Avian Diseases. 49:147-151.

USING SIGNATURE-TAGGED MUTAGENESIS TO IDENTIFY SALMONELLA ENTERICA SEROVAR TYPHIMURIUM GENES INVOLVED IN SURVIVAL IN THE SWINE STOMACH - (Abstract Only)

Bearson, S.M., Bearson, B.L., Jensen, A.M., Dolphin Rooney, H. 2004. Using signature-tagged mutagenesis to identify Salmonella enterica serovar Typhimurium genes involved in survival in the swine stomach [abstract]. American Society for Microbiology. p. 369-370.

EXPRESSION OF LDRD IN E. COLI O157:H7 AND SALMONELLA ENTERICA SEROVAR TYPHIMURIUM INHIBITS GROWTH - (Abstract Only)

Bearson, B.L., Casey, T., Bearson, S.M. 2004. Expression of ldrd in E. coli O157:H7 and Salmonella enterica serovar Typhimurium inhibits growth [abstract]. American Society for Microbiology. p. 297.

USING SUPPRESSION SUBTRACTIVE HYBRIDIZATION TO ANALYZE PORCINE DIFFERENTIAL GENE EXPRESSION FOLLOWING CHALLENGE WITH SALMONELLA ENTERICA SEROVAR CHOLERAESUIS - (Abstract Only)

Uthe, J.J., Stabel, T.J., Bearson, S.M., Zhao, S.H., Tuggle, C.K. 2004. Using suppression subtractive hybridization to analyze porcine differential gene expression following challenge with Salmonella enterica serovar Choleraesuis [abstract]. American Society for Microbiology. p. 208.

IDENTIFYING SALMONELLA ENTERICA SEROVAR TYPHIMURIUM GENES IMPORTANT FOR SURVIVAL IN THE SWINE STOMACH USING SIGNATURE-TAGGED MUTAGENESIS (GENOMIC SEQUENCE AND ANALYSIS CONFERENCE, SAVANNAH, GA, 9/21-24/03) - (Abstract Only)

BEARSON, S.M., BEARSON, B.L. IDENTIFYING SALMONELLA ENTERICA SEROVAR TYPHIMURIUM GENES IMPORTANT FOR SURVIVAL IN THE SWINE STOMACH USING SIGNATURE-TAGGED MUTAGENESIS. GENOMIC SEQUENCE AND ANALYSIS CONFERENCE. 2003. ABSTRACT p. P101.

GLUTATHIONE IS REQUIRED FOR ACID RESISTANCE IN E. COLI O157:H7 - (Abstract Only)

BEARSON, B.L., BEARSON, S.M., CASEY, T.A. GLUTATHIONE IS REQUIRED FOR ACID RESISTANCE IN E. COLI O157:H7. AMERICAN SOCIETY FOR MICROBIOLOGY. 2003. ABSTRACT P. 365.

INDUCTION OF A MYCOPLASMA GALLISEPTICUM PMGA GENE IN THE CHICKEN TRACHEAL RING ORGAN CULTURE MODEL - (Peer Reviewed Journal)

BEARSON, S.M., COLLIER, S.D., BEARSON, B.L., BRANTON, S.L. INDUCTION OF A MYCOPLASMA GALLISEPTICUM PMGA GENE IN THE CHICKEN TRACHEAL RING ORGAN CULTURE MODEL. AVIAN DISEASES. 2003. v. 47. p. 745-749.

INDUCTION OF THE MYCOPLASMA GALLISEPTICUM PMGA1.2 GENE IN THE CHICKEN TRACHEAL RING ORGAN CULTURE MODEL (INTERNATIONAL POULTRY SCIENTIFIC FORUM, ATLANTA, GA, 1/20-21/2003) - (Abstract Only)

BEARSON, S.M., COLLIER, S.D., BRANTON, S.L., BEARSON, B.L., MONTGOMERY, R.D. INDUCTION OF THE MYCOPLASMA GALLISEPTICUM PMGA1.2 GENE IN THE CHICKEN TRACHEAL RING ORGAN CULTURE MODEL. INTERNATIONAL POULTRY SCIENTIFIC FORUM. 2003. ABSTRACT P. 52.

OXYGEN AND NITRATE-DEPENDENT REGULATION OF DMSABC OPERON EXPRESSION IN ESCHERICHIA COLI: SITES FOR FNR AND NARL PROTEIN INTERACTIONS - (Peer Reviewed Journal) - (12-Jun-02)

EFFECT OF MYCOPLASMA GALLISEPTICUM S6 AND R STRAINS ON THE CILIARY ACTIVITY OF CHICKEN TRACHEAL RING ORGAN CULTURES - (Abstract Only) - (27-Nov-01)

THE EFFECTS OF 6/85 LIVE MYCOPLASMA GALLISEPTICUM VACCINE IN COMMERCIAL LAYER HENS OVER A 43-WEEK LAYING CYCLE ON EGG PRODUCTION, SELECTED EGG QUALITY PARAMETERS AND EGG SIZE DISTRIBUTION WHEN CHALLENGED BEFORE ... LAY - (Peer Reviewed Journal) - (23-Nov-01)

EFFECT OF MYCOPLASMA GALLINARUM ON SELECTED PRODUCTION PARAMETERS OF LAYER CHICKENS - (Abstract Only) - (10-Dec-00)

THE EFFECTS OF TS-11 STRAIN MYCOPLASMA GALLISEPTICUM VACCINATION IN COMMERCIAL LAYERS ON EGG PRODUCTION AND SELECTED EGG QUALITY PARAMETERS - (Peer Reviewed Journal) - (10-Apr-00)

THE EFFECT OF 6/85 STRAIN MYCOPLASMA GALLISEPTICUM ON EGG PRODUCTION, SELECTED EGG AND EGGSHELL QUALITY PARAMETERS AND EGG SIZE DISTRIBUTION IN COMMERCIAL LAYERS - (Abstract Only) - (25-Jan-00)

DELAY IN FATTY LIVER HEMORRHAGIC SYNDROME OBSERVED IN COMMERCIAL LAYERS INFECTED WITH MYCOPLASMA GALLINARUM - (Abstract Only) - (14-Nov-99)