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United States Department of Agriculture

Agricultural Research Service

Related Topics

Thomas Casey
National Animal Disease Center
Research Microbiologist

Phone: (515) 337-7726
Fax: (515) 337-7402
P.O. BOX 70
1920 DAYTON AVE
AMES, IA, 50010

Projects
PREVENTION AND CHARACTERIZATION OF PERSISTENT COLONIZATION BY E. COLI O157:H7 AND OTHER SHIGA TOXIN-PRODUCING E. COLI (STEC) IN CATTLE
Appropriated (D)
  Accession Number: 420815
ANIMAL INTESTINAL MICROBIOMES, FOODBORNE PATHOGENS, AND ANTIMICROBIALS
Appropriated (D)
  Accession Number: 420876

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Carbadox has both temporary and lasting effects on the swine gut microbiota - (Peer Reviewed Journal)
Looft, T.P., Allen, H.K., Casey, T., Alt, D.P., Stanton, T.B. 2014. Carbadox has both temporary and lasting effects on the swine gut microbiota. Frontiers in Microbiology. DOI: 10.3389/fmicb.2014.00276.
Finding alternatives to antibiotics Reprint Icon - (Peer Reviewed Journal)
Allen, H.K., Trachsel, J., Looft, T.P., Casey, T. 2014. Finding alternatives to antibiotics. Annals of the New York Academy of Sciences. Available: http://onlinelibrary.wiley.com/doi/10.1111/nyas.12468/abstract.
Escherichia coli O157:H7 lacking qseBC encoded quorum sensing system outcompetes the parent strain in colonization of cattle intestine Reprint Icon - (Peer Reviewed Journal)
Sharma, V.K., Casey, T. 2014. Escherichia coli O157:H7 lacking qseBC encoded quorum sensing system outcompetes the parent strain in colonization of cattle intestine. Applied and Environmental Microbiology. 80(6):1882-1892.
Determining the relative contribution and hierarchy of qseBC and hha in the regulation of flagellar motility of Escherichia coli O157:H7 - (Peer Reviewed Journal)
Sharma, V.K., Casey, T. 2014. Determining the relative contribution and hierarchy of qseBC and hha in the regulation of flagellar motility of Escherichia coli O157:H7. PLoS One. DOI: 10.1371/journal.pone.0085866.
Heat stress: intestinal barrier and immune disruption in pigs - (Abstract Only) - (23-Oct-13)
Fluorescence spectroscopy of the retina from scrapie-infected mice - (Peer Reviewed Journal)
Bose, S., Schonenbrucher, H., Richt, J.A., Casey, T., Rasmussen, M.A., Kehrli, Jr., M.E., Petrich, J.W. 2013. Fluorescence spectroscopy of the retina from scrapie-infected mice. Photochemistry and Photobiology. 89(4):864-868. Available: http://dx.doi.org/10.1111/php.12056.
Treatment, promotion, commotion: Antibiotic alternatives in food-producing animals Reprint Icon - (Peer Reviewed Journal)
Allen, H.K., Levine, U.Y., Looft, T.P., Bandrick, M.M., Casey, T. 2013. Treatment, promotion, commotion: Antibiotic alternatives in food-producing animals. Trends in Microbiology. 21(3):114-119.
Evaluation of heat-labile enterotoxins type IIa and type IIb in the pathogenicity of enterotoxigenic Escherichia coli for neonatal pigs - (Peer Reviewed Journal)
Casey, T., Connell, T.D., Holmes, R.K., Whipp, S.C. 2012. Evaluation of heat-labile enterotoxins type IIa and type IIb in the pathogenicity of enterotoxigenic Escherichia coli for neonatal pigs. Veterinary Microbiology. 3(18). Available: http://www.sciencedirect.com/science/article/pii/S037811351200185X.
A FaeG-FedF-LT192 fusion elicits protective anti-adhesin and antitoxin antibodies against porcine enterotoxigenic Escherichia coli - (Peer Reviewed Journal) - (26-Jul-11)
Evaluation of Hha and Hha SepB Mutant Strains of Escherichia coli O157:H7 as Bacterins for Reducing E. coli O157:H7 Shedding in Cattle - (Peer Reviewed Journal)
Sharma, V.K., Nystrom, E.A., Casey, T. 2011. Evaluation of hha and hha sepB mutant strains of Escherichia coli O157:H7 as bacterins for reducing E. coli O157:H7 shedding in cattle. Vaccine. 29(31):5078-5086. Available: http://www.sciencedirect.com/science/article/pii/S0264410X11006189.
Retinal Fluorescence Spectroscopy for Diagnosis of Transmissible Spongiform Encephalopathies - (Peer Reviewed Journal)
Adhikary, R., Mukherjee, P., Krishnamoorthy, G., Kunkle, R.A., Casey, T.A., Rasmussen, M.A., Petrich, J.W. 2010. Fluorescence Spectroscopy of the Retina for Diagnosis of Transmissible Spongiform Encephalopathies. Analytical Chemistry. 82(10):4097-4101.
Hha Represses Biofilm Formation in Escherichia coli O157:H7 by Affecting the Expression of Flagella and Curli Fimbriae - (Abstract Only)
Sharma, V.K., Bearson, B.L., Casey, T. 2010. Hha Represses Biofilm Formation in Escherichia coli O157:H7 by Affecting the Expression of Flagella and Curli Fimbriae[abstract]. American Society for Microbiology Meeting. p350.
Effect of chlorate, molybdate, and shikimic acid on Salmonella enterica serovar Typhimurium in aerobic and anaerobic cultures Reprint Icon - (Peer Reviewed Journal)
Oliver, C.E., Beier, R.C., Hume, M.E., Horrocks, S.M., Casey, T., Caton, J.S., Nisbet, D.J., Smith, D.J., Krueger, N.A., Anderson, R.C. 2010. Effect of chlorate, molybdate, and shikimic acid on Salmonella enterica serovar Typhimurium in aerobic and anaerobic cultures. Anaerobe. 16:106-113.
A comparison of the fluorescence spectra of murine and bovine central nervous system (CNS) and other tissues - (Peer Reviewed Journal)
Adhikary, R., Schonenbrucher, H.H., Rasmussen, M.A., Casey, T., Hamir, A.N., Kehrli Jr, M.E., Richt, J., Petrich, J.W. 2009. A Comparison of the Fluorescence Spectra of Murine and Bovine Central Nervous System (CNS) and Other Tissues. Photochemistry and Photobiology. 85(6):1322-1326.
Escherichia coli O157:H7 Glutamate- and Arginine-dependent Acid Resistance Systems Protect Against Oxidative Stress During Extreme Acid Challenge Reprint Icon - (Peer Reviewed Journal)
Bearson, B.L., Lee, I., Casey, T. 2009. Escherichia coli O157:H7 Glutamate- and Arginine-dependent Acid Resistance Systems Protect Against Oxidative Stress During Extreme Acid Challenge. Microbiology. 155(3):805-812.
Design and Evaluation of a Multiplex PCR Assay for the Simultaneous Identification of Genes for Nine Different Virulence Factors Associated with Escherichia coli that Cause Diarrhea and Edema Disease in Swine - (Peer Reviewed Journal)
Casey, T., Bosworth, B.T. 2009. Design and Evaluation of a Multiplex PCR Assay for the Simultaneous Identification of Genes for Nine Different Virulence Factors Associated with Escherichia coli that Cause Diarrhea and Edema Disease in Swine. Journal of Veterinary Diagnostic Investigation. 21(1):25-30.
Monitoring the accumulation of lipofuscin in aging murine eyes by fluorescence spectroscopy - (Peer Reviewed Journal)
Mukherjee, P., Bose, S., Hurd, A.A., Adhikary, R., Schonenbrucher, H., Hamir, A.N., Richt, J.A., Casey, T.A., Rasmussen, M.A., Petrich, J.W. 2009. Monitoring the Accumulation of Lipofuscin in Aging Murine Eyes by Fluorescence Spectroscopy. Photochemistry and Photobiology. 85(1):234-238.
A fluorescence based method, exploiting lipofuscin, for the real-time detection of central nervous system (CNS) tissues on bovine carcasses Reprint Icon - (Peer Reviewed Journal)
Schonenbrucher, H., Adhikary, R., Mukherjee, P., Casey, T.A., Rasmussen, M.A., Maistrovich, F.D., Hamir, A.N., Kehrli, Jr., M.E., Richt, J.A., Petrich, J.W. 2008. Fluorescence-Based Method, Exploiting Lipofuscin, for Real-Time Detection of Central Nervous System Tissues on Bovine Carcasses. Journal of Agricultural and Food Chemistry. 56(15):6220-6226.
Escherichia coli O157:H7 Glutamate- and Arginine-dependent Acid Resistance Systems Protect Against Oxidative Stress During Extreme Acid Challenge - (Abstract Only)
Bearson, B.L., Casey, T., Lee, I. 2008. Escherichia coli O157:H7 glutamate- and arginine-dependent acid resistance systems protect against oxidative stress during extreme acid challenge. Proceedings of 48th Microbiology Society of Korea Annual Meeting & 2008 International Symposium on Microbiology, May 15-16, 2008, Daejeon, Korea. p. 210.
Fluorescence of tissues fluororophores such as lipofuscin as a possible basis for the detection of CNS tissues on bovine carcasses - (Abstract Only)
Schonenbrucher, H., Adhikary, R., Maistrovich, F., Casey, T.A., Rasmussen, M.A., Mukherje, P., Kehrli, Jr., M.E., Petrich, J.W., Richt, J.A, 2007. Fluorescence of tissues fluororophores such as lipofuscin as a possible basis for the detection of CNS tissues on bovine carcasses [abstract]. Conference of Research Workers in Animal Diseases Annual Meeting. Paper No. 66P. p. 104.
Bovine Immune Response to Shiga-Toxigenic Escherichia Coli O157:h7 - (Peer Reviewed Journal)
Hoffman, M.A., Menge, C., Casey, T., Laegreid, W.W., Bosworth, B.T., Nystrom, E.A. 2006. Bovine immune response to Shiga-toxigenic Escherichia coli O157:H7. Clinical and Vaccine Immunology. 13(12):1322-1327.
Effect of chlorate, molybdate, and shikimic acid on Salmonella Typhimurium in aerobic and anaerobic cultures - (Abstract Only)
Oliver, C.E., Smith, D.J., Casey, T., Horrocks, S.M., Anderson, R.C., Nisbet, D.J. 2006. Effect of chlorate, molybdate, and shikimic acid on Salmonella Typhimurium in aerobic and anaerobic cultures. American Society of Microbiology National Meetings Victoria, British Columbia, Sept. 10-12, 2006. Abstract No. 85.
Differential Regulation of Sepl and Esp Genes of Enterohemorrhagic Escherichia Coli O157:h7 - (Abstract Only)
Sharma, V.K., Casey, T., Morgan, R.W. 2005. Differential regulation of sepL and esp genes of enterohemorrhagic Escherichia coli O157:H7 [abstract]. Joint Meeting of the 3 Divisions of the International Union of Microbiological Societies. p. 159.
Hyperadherence of An Hha Mutant of Escherichia Coli O157:h7 Is Correlated with Enhanced Expression of Lee-Encoded Adherence Genes - (Peer Reviewed Journal)
Sharma, V.K., Carlson, S.A., Casey, T. 2005. Hyperadherence of an hha mutant of Escherichia coli O157:H7 is correlated with enhanced expression of LEE-encoded adherence genes. Federation of European Microbiological Societies Microbiology Letters. 243(1):189-196.
Meat Carcass Inspection Using the Fluorescence of Dietary Porphyrins - (Abstract Only)
Rasmussen, M.A., Casey, T., Petrich, J.W. Meat carcass inspection using the fluorescence of dietary porphyrins [abstract]. 2004 Joint Annual Meeting of the American Dairy Science Association, American Society of Animal Science, Poultry Science Association. p. 166.
Expression of Ldrd in E. Coli O157:h7 and Salmonella Enterica Serovar Typhimurium Inhibits Growth - (Abstract Only)
Bearson, B.L., Casey, T., Bearson, S.M. 2004. Expression of ldrd in E. coli O157:H7 and Salmonella enterica serovar Typhimurium inhibits growth [abstract]. American Society for Microbiology. p. 297.
Oral Dosing of Mice with Escherichia Coli Expressing Recombinant Interferon Gamma Reduces Cryptosporidium Parvum Infection - (Abstract Only)
Harp, J.A., Oesper, J.C., Casey, T. 2003. Oral dosing of mice with Escherichia coli expressing recombinant interferon gamma reduces Cryptosporidium parvum infection [abstract]. ARS Immunology Workshop. p. 59.
Oral Dosing of Mice with Escherichia Coli Expressing Recombinant Interferon Gamma Reduces Cryptosporidium Parvum Infection - (Abstract Only)
Harp, J.A., Oesper, J.C., Casey, T. 2003. Oral dosing of mice with Escherichia coli expressing recombinant interferon gamma reduces Cryptosporidium parvum infection [abstract]. Conference Research Workers Disease Meeting. p. 93P.
Generation of Fluorescent Adducts of Malondialdehyde and Amino Acids: Towards An Understanding of Lipofuscin - (Peer Reviewed Journal)
Chowdhury, P.K., Halder, M., Choudhury, P.K., Kraus, G. A., Desai, M.J., Armstrong, D.W. Casey, T.A., Rasmussen, M.A., Petrich, J.W. 2004. Generation of fluorescent adducts of malondialdehyde and amino acids: towards an understanding of lipofuscin. Photochemistry and Photobiology. 79:21-25.
Fluorescent Detection of Fecal Contamination on Animal Carcasses (Oral Presentation) - (Abstract Only)
RASMUSSEN, M.A., CASEY, T.A., PETRICH, J.W. FLUORESCENT DETECTION OF FECAL CONTAMINATION ON ANIMAL CARCASSES. CONFERENCE ON GASTROINTESTINAL FUNCTION. 2003. ABSTRACT P. 21.
Fluorescence of Dietary Porphyrins As a Basis for Real-Time Detection of Fecal Contamination on Meat - (Peer Reviewed Journal)
ASHBY, K.D., WEN, J., CHOWDHURY, P., CASEY, T., RASMUSSEN, M.A., PETRICH, J.W. FLUORESCENCE OF DIETARY PORPHYRINS AS A BASIS FOR REAL-TIME DETECTION OF FECAL CONTAMINATION ON MEAT. JOURNAL OF AGRICULTURE AND FOOD CHEMISTRY. 2003. V. 51. P. 3502-3507.
Glutathione Is Required for Acid Resistance in E. Coli O157:h7 - (Abstract Only)
BEARSON, B.L., BEARSON, S.M., CASEY, T.A. GLUTATHIONE IS REQUIRED FOR ACID RESISTANCE IN E. COLI O157:H7. AMERICAN SOCIETY FOR MICROBIOLOGY. 2003. ABSTRACT P. 365.
Fluorescence Spectoscopy for Detecting Fecal Contamination on Animal Carcasses - (Abstract Only)
CASEY, T., RASMUSSEN, M.A., PETRICH, J.W. FLUORESCENCE SPECTOSCOPY FOR DETECTING FECAL CONTAMINATION ON ANIMAL CARCASSES. INTERNATIONAL CONFERENCE ON EMERGING ZOONOSES. 2003. ABSTRACT p. 17.
A High-Throughput Genetic System for Assessing the Inhibition of Proteins: Identification of Antibiotic Resistance and Virulence Targets and the Cognate Inhibitors in Salmonella - (Peer Reviewed Journal)
CARLSON, S.A., CASEY,T.A., WU, M.T., HAMMES,B.D., JONES,B.D. A HIGH-THROUGHPUT GENETIC SYSTEM FOR ASSESSING THE INHIBITION OF PROTEINS: IDENTIFICATION OF ANTIBIOTIC RESISTANCE AND VIRULENCE TARGETS AND THE COGNATE INHIBITORS IN SALMONELLA. ANALYTICAL BIOCHEMISTRY. 2002. V. 310. P. 72-83.
Fluorescence Based Real-Time Detection of Faecal Contamination on Meat - (Popular Publication)
CASEY, T.A., RASMUSSEN, M.A., PETRICH, J.W. FLUORESCENCE BASED REAL-TIME DETECTION OF FAECAL CONTAMINATION ON MEAT. AVAILABLE FROM: HTTP://WWW.CAMPDEN.CO.UK/PUBL/PUBFILES/MICFORUM.HTM MICROBIOLOGICAL METHODS FORUM [2002].
A High-Throughput Genetic System for Identifying and Characterizing Oligopeptide-Protein Interactions That Inhibit Antibiotic Resistance and Virulence in Bacteria (Strategies for Id/development of Novel Antimicrob) - (Abstract Only) - (05-Feb-02)
Environmental and Food Safety Aspects of Escherichia Coli O157:h7 Infections in Cattle - (Review Article) - (27-Apr-01)
Environmental and Food Safety Aspects of Escherichia Coli O157:h7 Infections in Cattle - (Peer Reviewed Journal) - (15-Apr-01)
E. Coli, Cattle, and the Environment - (Abstract Only) - (08-Jan-01)
Steady-State and Time-Resolved Spectroscopy of F420 Extracted from Methanogen Cells and Its Utility As a Marker for Fecal Contamination - (Peer Reviewed Journal) - (07-Dec-00)
Application of a Multiplex Pcr Assay for Simultaneous Detection of Shiga Toxigenic Escherichia Coli and Enterohemorrhagic E. Coli of Serotypes O157:h7, O26, and O111 - (Abstract Only) - (02-Nov-00)
Detection of Fecal and Ingesta Contamination on Meat Surfaces Utilizing Intrinsic Fluorescent Markers - (Abstract Only) - (26-Sep-00)
Persistent Colonization of Sheep by Escherichia Coli O157:h7 and Other E. Coli Pathotypes - (Peer Reviewed Journal) - (15-Sep-00)
Letter to the Editor: Is Escherichia Coli Stb Enterotoxin Sufficient to Cause Pig Diarrhea? - (Other) - (08-Dec-99)
Are Ruminants a Biological Or Accidental Reservoir for Vtec O157? - (Abstract Only) - (10-Nov-99)
Are Ruminants a Biological Or Accidental Reservoir for Vtec O157? - (Proceedings) - (10-Nov-99)
Detection of Fecal and Ingesta Contamination on Meat Surfaces Utilizing Intrinsic Fluorescent Markers - (Abstract Only) - (16-Oct-99)
Antimicrobial Effect of Acidified Nitrite on Escherichia Coli O157:h7 - (Abstract Only) - (15-Oct-99)
Method and System for Detecting Fecal and Ingesta Contamination on Meat Carcasses - (Abstract Only) - (27-Sep-99)
Development of Fluorogenic Pcr Assays for Rapid Detection of Virulence Genes of Escherichia Coli O157:h7 and Other Shiga Toxigenic E. Coli (Virulence Mechanisms of Bacterial Pathogens, 9/12-15/99, Ames, Ia) - (Abstract Only) - (15-Sep-99)
Model for Competitive Colonization of Sheep by E. Coli O157:h7 - (Abstract Only) - (03-Jun-99)
Semi-Automated Fluorescent (Taqman) Pcr Assays for Rapid Detection of Escherichia Coli O157:h7 and Other Shiga Toxigenic E. Coli (Stec) - (Abstract Only) - (03-Jun-99)
Semi-Automated Fluorogenic Pcr Assays (Taqman) for Rapid Detection of Escherichia Coli O157:h7 and Other Shiga Toxigenic E. Coli - (Peer Reviewed Journal) - (13-May-99)
Method and Devices to Detect Fecal Contamination on Carcasses - (Abstract Only) - (03-Dec-98)
Possible Targets for E. Coli O157:h7 Vaccines in Cattle - (Abstract Only) - (03-Dec-98)
Escherichia Coli O157:h7 and the Rumen Environment (Escherichia Coli O157 in Farm Animals) - (Book / Chapter) - (25-Sep-98)
Effects of Parturition on Fecal Coliform Shedding of Dairy Cows - (Peer Reviewed Journal) - (27-Apr-98)
Escherichia Coli O157:h7 and the Rumen Environment (Farm Animals As a Reservoir for Escherichia Coli O157) - (Abstract Only) - (07-Apr-98)
Effect of Dietary Stress on Fecal Shedding of Escherichia Coli O157:h7 in Calves (Note) - (Peer Reviewed Journal) - (08-Mar-98)
Differentiation of F18ab**+ from F18ac**+ Escherichia Coli Using Single Strand Conformational Polymorphism Analysis of the Major Fimbrial Subunit Gene (Feda) - (Peer Reviewed Journal) - (21-Jan-98)
Expression of Heat-Stable Enterotoxin Stb by Adherent Escherichia Coli Is Not Sufficient to Cause Severe Diarrhea in Neonatal Pigs - (Peer Reviewed Journal) - (30-Dec-97)
Competitive Colonization of Sheep by E. Coli O157:h7 - (Abstract Only) - (13-Nov-97)
Detection of Cd1, Swc1, Swc2 and Cd45 Molecules by Immunofluorescence Or Immunoperoxidase Techniques in Porcine Gut-Associated Lymphoid Tissues Following Experimentally Induced Colibacillosis - (Peer Reviewed Journal) - (01-Jul-97)
Bovine Immune Response to Escherichia Coli O157:h7 - (Abstract Only) - (26-Jun-97)
Effects of Parturition on Fecal Coliform Shedding from Dairy Cows - (Abstract Only) - (25-Jun-97)
Identification of Toxin and Pilus Genes in Porcine Escherichia Coli Using Polymerase Chain Reaction (Pcr) with Multiple Primer Pairs - (Abstract Only) - (08-May-97)
Rumen Bacteria That Reduce Selenium - (Abstract Only) - (08-May-97)
Effects of Parturition on Fecal Coliform Shedding from Dairy Cows - (Abstract Only) - (20-Apr-97)
Effects of Parturition on Feed Intake and Fecal Coliform Shedding - (Abstract Only) - (06-Nov-96)
Diagnosis and Control of Post-Weaning Colibacillosis in Pigs - (Abstract Only) - (13-Oct-96)
Shedding of Escherichia Coli O157:h7 in Cattle (Us-Japan Mycoplasmosis MTG., Ames, Ia) - (Abstract Only) - (04-Sep-96)
Shedding of Escherichia Coli O157:h7 in Cattle - (Abstract Only) - (04-Sep-96)
Biologic Relationship Between F107 (F18ab) and 2134p (F18ac) Fimbriae of Enterotoxigenic and Verotoxigenic Escherichia Coli Isolated from Weaned Pigs - (Peer Reviewed Journal) - (22-Aug-96)
Effect of Dietary Stress in Ruminants on Fecal Shedding of Coliforms and Escherichia Coli 0157:h7 - (Abstract Only) - (12-Dec-95)
Effect of Dietary Stress on Infection of Calves by Escherichia Coli O157:h7 - (Abstract Only) - (14-Nov-95)
The Effects of Fasting Stress and Dexamethasone on Neutrophil Cd621 Expression in Calves Harboring E. Coli 0157:h7 - (Abstract Only) - (14-Nov-95)
Genetic Resistance to Porcine Post-Weaning Diarrhea Caused by Enterotoxigenic Escherichia Coli That Express 2134p Pili - (Abstract Only) - (28-Oct-95)
Dietary Stress in Ruminants and Escherichia Coli 0157:h7 - (Abstract Only) - (26-Jul-95)
Identification and Distribution of Cd**+ T-Cell Subsets in Porcine Gut Following Experimental Infection with F4ac**+ Enterotoxigenic Escherichia Coli (Etec) Or Non-Etec Strains - (Peer Reviewed Journal) - (19-May-95)
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Last Modified: 11/21/2014
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