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Agricultural Research Service United States Department of Agriculture
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TMRU Main Office
Lab of Charles W. Bacon
Lab of Anthony E. Glenn
Lab of Ronald T. Riley
Lab of Kenneth A. Voss
Lab of Ida E. Yates
TMRU Support Scientists
 

Ronald T Riley (Ron)
Toxicology and Mycotoxin Research
RESEARCH TOXICOLOGIST

Phone: (706) 546-3377
Fax: (706) 546-3116
Room 361
USDA, ARS, SAA
RBRRC
950 COLLEGE STATION ROAD
ATHENS, GA, 30605-2720

Projects
Biocontrol of Fumonisin and Other Mycotoxins in Corn and Tall Fescue with Microbial Endophytes
Appropriated (D)
  Accession Number: 410519
Minimizing the Adverse Health and Economic Impacts of Mycotoxins and Plant Toxins in Foods
Appropriated (D)
  Accession Number: 410320

Publications
Hydrolyzed fumonisin B1 (HFB1) did not cause neural tube defects when evaluated using the LM/Bc mouse model - (Abstract)
Voss, K.A., Burns, T., Snook, M.E., Riley, R.T., Gelineau-Van Waes, J. 2009. Hydrolyzed fumonisin B1 (HFB1) did not cause neural tube defects when evaluated using the LM/Bc mouse model. Proceedings of November, 2008,Scientific Presentations at the United States-Japan Cooperative Program in Natural Resources, New Orleans, LA.
Reproductive and sphingolipid metabolic effects of fumonisin B1 and its alkaline hydrolysis product in LM/Bc mice: hydrolyzed fumonisin B1 did not cause neural tube defects - (Peer Reviewed Journal) - (02-Sep-09)
Hepatotoxic Mycotoxins - (Book/Chapter) - (06-Jul-09)
A bioassay approach for determining the effect of cooking on fumonisin toxicity - (Abstract)
Voss, K.A., Burns, T.D., Ryu, D., Jackson, L.S., Bullerman, L.B., Riley, R.T., Gelineau-Van Waes, J. 2009. A bioassay approach for determining the effect of cooking on fumonisin toxicity. Proceedings of presentations for the German Society for Mycotoxin Research Annual Workshop, Muenster, Germany, June 2009.
Comparing the reproductive toxicity of fumonisin B1 (FB1) and hydrolyzed fumonisin B1 (HFB1): only FB1 induced neural tube defects in LM/Bc Mice - (Abstract)
Voss, K.A., Burns, T.D., Snook, M.E., Riley, R.T., Gelineau-Van Waes, J.B. 2009. Comparing the reproductive toxicity of fumonisin B1 (FB1) and hydrolyzed fumonisin B1 (HFB1): only FB1 induced neural tube defects in LM/Bc Mice. Proceedings of the 20009 Annual Meeting of the Center for Food Safety, University of Georgia, Athens, Georgia.
Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxy-sphinganine: a novel category of bioactive 1-deoxy-sphingoid bases and 1-deoxy-dihydroceramides biosynthesized by mammalian cell lines and animals - (Peer Reviewed Journal)
Zitomer, N.C., Mitchell, T.R., Voss, K.A., Bondy, G.S., Pruett, S.T., Garnier-Amblard, E.C., Liebeskind, L.S., Park, H., Wang, E., Sullards, M., Merrill, A.H., Riley, R.T. 2009. Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxy-sphinganine: a novel category of bioactive 1-deoxy-sphingoid bases and 1-deoxy-dihydroceramides biosynthesized by mammalian cell lines and animals. Journal of Biological Chemistry. 284(8):4786-4795.
Accumulation of 1-Deoxysphinganine in mammalian cells and tissues following fumonisin inhibition of ceramide synthase: a novel category of bioactive sphingoid bases and 1-Deoxydihydroceramides - (Abstract)
Riley, R.T., Zitomer, N.C., Mitchell, T.R., Voss, K.A., Bondy, G.S., Pruett, S.T., Garnier, E., Liebeskind, L.S., Park, H., Wang, E., Sullards, C., Merrill, A.H. 2009. Accumulation of 1-Deoxysphinganine in mammalian cells and tissues following fumonisin inhibition of ceramide synthase: a novel category of bioactive sphingoid bases and 1-Deoxydihydroceramides. Toxicological Sciences 108:132.
Hydrolyzed fumonisin B1 (HFB1) did not induce neural tube defects in LM/Bc mice - (Abstract)
Voss, K.A., Burns, T.D., Snook, M.E., Riley, R.T., Gelineau-Van Waes, J. 2009. Hydrolyzed fumonisin B1 (HFB1) did not induce neural tube defects in LM/Bc mice. Toxicological Sciences 108:156.
Placental and neural tube defects after maternal fumonisin or FRY720 exposure - (Abstract)
Gelineau-Van Waes, J., Maddox, J., Wilberding, J., Voss, K.A., Riley, R.T. 2009. Placental and neural tube defects after maternal fumonisin or FRY720 exposure. Toxicological Sciences 108:132.
Isolation and characterization of 1-Deoxysphinganine, a novel sphingoid base that accumulates in cells following fumonisin B1 inhibition of ceramide synthase - (Abstract)
Zitomer, N.C., Mitchell, T.R., Voss, K.A., Pruett, S.T., Garnier, E., Liebeskind, L.S., Park, H., Wang, E., Sullards, C., Merrill, A.H., Riley, R.T. 2009. Isolation and characterization of 1-Deoxysphinganine, a novel sphingoid base that accumulates in cells following fumonisin B1 inhibition of ceramide synthase. Toxicological Sciences 108:132.
Maternal fumonisin exposure as a risk factor for neural tube defects - (Book/Chapter)
Gelineau-Van Waes, J., Voss, K.A., Stevens, V.L., Speer, M.C., Riley, R.T. 2009. Maternal fumonisin exposure as a risk factor for neural tube defects. In: Taylor, S., editor. Advances in Food and Nutrition Research. Amsterdam, The Netherlands:Elsevier/Academic Press. p.145-181.
Fungal endophyte metabolism and allelopathic interactions with host plants - (Abstract) - (27-Jun-08)
A single extraction method for the analysis by liquid chromatography/tandem mass spectrometry of fumonisins and biomarkers of disrupted sphingolipid metabolism in tissues of maize seedlings - (Abstract) - (16-Jun-08)
Fumonisin concentrations and in vivo toxicity of nixtamalized Fusarium verticillioides culture material: evidence for Fumonisin-matrix interactions. - (Peer Reviewed Journal)
Burns, T.D., Snook, M.E., Riley, R.T., Voss, K.A. 2008. Fumonisin concentrations and in vivo toxicity of nixtamalized Fusarium verticillioides culture material: evidence for Fumonisin-matrix interactions. Food and Chemical Toxicology. 46:2841-2848.
A single extraction method for the analysis by liquid chromatography/tandem mass spectrometry of fumonisins and biomarkers of disrupted sphingolipid metabolism in tissues of maize seedlings - (Peer Reviewed Journal)
Zitomer, N.C., Glenn, A.E., Bacon, C.W., Riley, R.T. 2008. A single extraction method for the analysis by liquid chromatography/tandem mass spectrometry of fumonisins and biomarkers of disrupted sphingolipid metabolism in tissues of maize seedlings. Analytical and Bioanalytical Chemistry. 391:2257-2263.
Transformation-mediated complementation of a FUM gene cluster deletion in Fusarium verticillioides restores both fumonisin production and pathogenecity on maize seedlings. - (Peer Reviewed Journal)
Glenn, A.E., Zitomer, N.C., Zimeri, A.M., Williams, L.D., Riley, R.T., Proctor, R. 2008. Transformation-mediated complementation of a FUM gene cluster deletion in Fusarium verticillioides restores both fumonisin production and pathogenecity on maize seedlings. Molecular Plant-Microbe Interactions. 21-87-97.
Fumonisin mycotoxin contamination of corn-based foods consumed by potentially pregnant women in Southern California - (Peer Reviewed Journal)
Dvorak, N.J., Riley, R.T., Harris, M., Mcgregor, J.A. 2008. Fumonisin mycotoxin contamination of corn-based foods consumed by potentially pregnant women in Southern California. The Journal of Reproductive Medicine. 53:672-676.
Accumulation of sphingoid bases, the structural sphingoid base analog FTY720 and their phosphorylated metabolites in blood, plasma and decidua of SWV and LMBC mice treated with Fumonisin B1 or FTY720 - (Abstract) - (07-Dec-07)
Fumonisin concentrations and in vivo toxicity after nixtamalization of corn culture material: evidence for fumonisin-matrix binding - (Abstract) - (03-Nov-07)
Characterization and complementation of an apparent FUM gene cluster deletion in Fusarium verticillioides. - (Abstract) - (24-Oct-07)
Disruption of ceramide biosynthesis and accumulation of sphingoid bases and sphingoid base 1-phosphates: A mechanism for Fusarium verticillioides effects in maize-seedling disease. - (Abstract) - (24-Oct-07)
Effect of nixtamalization with and without corn matrix on the concentration and toxicity of fumonisins in Fusarium verticillioides culture material. - (Abstract) - (14-Oct-07)
Estimated Fumonisin Exposure in Guatemala Greatest in Consumers of Lowland Maize - (Peer Reviewed Journal)
Torres, O.A., Palencia, E.R., Lopez De Pratdesaba, L., Grajeda, R., Fuentes, M., Speer, M.C., Merrill Jr, A.H., O Donnell, K., Bacon, C.W., Glenn, A.E., Riley, R.T. 2007. Estimated Fumonisin Exposure in Guatemala Greatest in Consumers of Lowland Maize. Journal of Nutrition. 137(12):2723-2729.
An historical overview of field disease outbreaks known or suspected to be caused by consumption of feeds contaminated with Fusarium toxins - (Review Article)
Morgavi, D.P., Riley, R.T. 2007. An historical overview of field disease outbreaks known or suspected to be caused by consumption of feeds contaminated with Fusarium toxins. Animal Feed Science And Technology. 137:201-212.
Fusarium and their toxins: Mycology, occurrence, toxicity, control, and economic impact - (Review Article)
Morgavi, D.P., Riley, R.T. 2007. Fusarium and their toxins: Mycology, occurrence, toxicity, control, and economic impact. Animal Feed Science And Technology. 137:199-200.
Characterization and complementation of a fumonisin biosynthetic gene cluster deletion in banana isolates of Fusarium verticillioides - (Abstract)
Glenn, A.E., Zitomer, N.C., Riley, R.T., Proctor, R. 2007. Characterization and complementation of a fumonisin biosynthetic gene cluster deletion in banana isolates of Fusarium verticillioides. Phytopathology. 97:S41.
Fetotoxicity and neural tube defects in CD1 mice exposed to the mycotoxin Fumonisin B1 - (Proceedings/Symposium)
Voss, K.A., Riley, R.T., Gelineau Van-Waes, J. 2007. Fetotoxicity and neural tube defects in CD1 mice exposed to the mycotoxin Fumonisin B1. International Symposium of Mycotoxicology Meeting. Mycotoxins 57S:67-72.
Inducible nitric oxide has protective effect on fumonisin B1 hepatotoxicity in mice via modulation of sphingosine kinase - (Peer Reviewed Journal)
Suzuki, H., Riley, R.T., Sharma, R.P. 2007. Inducible nitric oxide has protective effect on fumonisin B1 hepatotoxicity in mice via modulation of sphingosine kinase. Toxicology 229:42-53.
Toxicological Evaluation of Fusarium verticillioides Culture Material Nixtamalized in the Presence and Absence of Corn Matrix - (Abstract) - (19-Mar-07)
Toxicity of fumonisin-contaminated fungal cultures nixtamalized in the presence and absence of corn matrix. - (Abstract) - (30-Jan-07)
Fumonisin Disruption of Ceramide Biosynthesis in Maize Roots and the Effects on Plant Development and Fusarium verticillioides-Induced Seedling Disease - (Peer Reviewed Journal)
Williams, L.D., Glenn, A.E., Zimeri, A.M., Bacon, C.W., Smith, M.A., Riley, R.T. 2007. Fumonisin Disruption of Ceramide Biosynthesis in Maize Roots and the Effects on Plant Development and Fusarium verticillioides-Induced Seedling Disease. Journal of Agricultural and Food Chemistry. 55:2937-2946.
Toxicity of fumonisins, mycotoxins from Fusarium verticillioides - (Book/Chapter)
Voss, K.A., Riley, R.T., Gelineau-Van Waes, J.B. 2007. Toxicity of fumonisins, mycotoxins from Fusarium verticillioides. In: Wilson, C.L., editor. Microbial Food Contamination. Boca Raton, FL:CRC Press. p. 107-126.
Fetotoxicity and neural tube defects on CD1 mice exposed to the mycotoxin fumonisin b1 - (Abstract) - (04-Dec-06)
Increased accumulation of fumonisin B1, sphingoid bases and sphingoid base 1-phosphates: explaining the differential sensitivity of rat kidney and liver to fumonisin toxicity. - (Abstract)
Riley, R.T., Voss, K.A. 2007. Increased accumulation of fumonisin B1, sphingoid bases and sphingoid base 1-phosphates: explaining the differential sensitivity of rat kidney and liver to fumonisin toxicity. Toxicological Sciences. Abst. 1450, p. 200.
Toxicological evaluation of Fusarium verticillioides culture material nixtamalized in the presence and absence of corn matrix. - (Abstract)
Burns, T., Snook, M.E., Riley, R.T., Mitchell, T.R., Voss, K.A. 2007. Toxicological evaluation of Fusarium verticillioides culture material nixtamalized in the presence and absence of corn matrix. Toxicological Sciences. Abst. 726, p. 138.
Fumonisin production is necessary for development of the full spectrum of symptoms indicative of Fusarium verticillioides maize-seedling disease and evidence for disruption of sphingolipid metabolism as the proximate cause. - (Abstract)
Williams, L.D., Glenn, A.E., Bacon, C.W., Smith, M.A., Riley, R.T. 2007. Fumonisin production is necessary for development of the full spectrum of symptoms indicative of Fusarium verticillioides maize-seedling disease and evidence for disruption of sphingolipid metabolism as the proximate cause. Toxicological Sciences. Abst. 550, p. 118.
Necessity of fumonisin production by Fusarium verticillioides for Foliar disease on corn seedlings and evaluation of absorption and translocation of the mycotoxin - (Abstract) - (07-Nov-06)
Fumonisin Production and Bioavailability to Maize Seedlings Grown from Seeds Inoculated with Fusarium Verticillioides and Grown in Natural Soils - (Peer Reviewed Journal)
Williams, L.D., Glenn, A.E., Bacon, C.W., Smith, M.A., Riley, R.T. 2006. Fumonisin production and bioavailability to maize seedlings grown from seeds inoculated with fusarium verticillioides and grown in natural soils. Journal of Agricultural and Food Chemistry 54(15):5694-5700.
The mycotoxin fumonisin B1 is necessary for corn seedling disease development and is translocated from roots to shoot. - (Abstract)
Zimeri, A.M., Williams, L.D., Riley, R.T., Glenn, A.E. 2006. The mycotoxin fumonisin B1 is necessary for corn seedling disease development and is translocated from roots to shoot {abstract}. Phytopathology 96:S131.
Fumonisins in Maize in Guatemala, Preliminary Exposure Estimate and Policies and Recommendations to Minimize Exposure - (Abstract)
Riley, R.T., Torres, O.A., Palencia, E.R., De Pratdesaba, L., Glenn, A.E., O Donnell, K., Fuentes, M. 2006. Fumonisins in maize in guatemala, preliminary exposure estimate and policies and recommendations to minimize exposure. Association Official Analytical Chemists Southern Section Program Abstracts. Atlanta, GA.
Differential Sensitivity of Rat Kidney and Liver to Fumonisin Toxicity: Organ Specific Differences in Toxin Accumulation and Sphingoid Base Metabolism - (Peer Reviewed Journal)
Riley, R.T., Voss, K.A. 2006. Differential sensitivity of rat kidney and liver to fumonisin toxicity: organ specific differences in toxin accumulation and sphingoid base metabolism. Toxicological Sciences. 92(1):335-345.
International shipping of fumonisins from maize extracts on C18 sorbent - (Peer Reviewed Journal)
Riley, R.T., Torres, O.A., Palencia, E. 2006. International shipping of fumonisins from maize extracts on C18 sorbent. Food Additives and Contaminants 23(8):826-832.
The Role of Tumor Necrosis Factor Alpha and the Peroxisome Proliferator-Activated Receptor Alpha in Moldulating the Effects of Fumonisin in Mouse Liver - (Peer Reviewed Journal)
Corton, J., Riley, R.T., Dunn, C., Voss, K.A. 2006. The role of tumor necrosis factor alpha and the peroxisome proliferator-activated receptor alpha in moldulating the effects of fumonisin in mouse liver. Toxicology 222:165-174.
Fumonisins and Neural Tube Defects: Reproductive Toxicity Studies in the Lm/bc and Cd1 Mouse Strains - (Abstract) - (15-Feb-06)
Fumonisin Inhibition of Ceramide Synthase: a Possible Risk Factor for Human Neural Tube Defects - (Book/Chapter)
Riley, R.T., Voss, K.A., Speer, M., Stevens, V.L., Gelineau-Van Waes, J. 2006. Fumonisin inhibition of ceramide synthase: a possible risk factor for human neural tube defects. In: Hirabayashi, U., Igarashi, I., Merrill, Jr., A.H., editors. Sphingolipid Biology. Heidelberg, Germany: Springer. p.345-361.
Fumonisins: Current Research Trends in Developmental Toxicology - (Proceedings/Symposium)
Voss, K.A., Gelineau-Van Waes, J., Riley, R.T. 2006. Fumonisins: current research trends in developmental toxicology. Mycotoxin Research 22(1):61-69.
Induction of Neural Tube Defects in Cd1 Mice by Intraperitoneal Exposure to Fumonisin B1 - (Abstract)
Burns, T.D., Riley, R.T., Gelineau-Van Waes, J.B., Voss, K.A. 2006. Induction of neural tube defects in cd1 mice by intraperitoneal exposure to fumonisin b1[abstract]. Toxicological Sciences. 90(1):408.
Gene-Nutrient-Environment Interactions As Risk Factors for Birth Defects: Fumonisin, Folate, Genetic Variation and Neural Tube Defects - (Abstract)
Gelineau-Van Waes, J., Riley, R.T. 2006. Gene-nutrient-environment interactions as risk factors for birth defects: fumonisin, folate, genetic variation and neural tube defects [abstract]. Toxicological Sciences 90(1):305.
Evidence for Increased Sphingoid Base 1-Phosphate Lyase Activity in Corn Seedlings after Prolonged Exposure to Fumonisin - (Abstract)
Williams, L.D., Glenn, A.E., Bacon, C.W., Smith, M.A., Riley, R.T. 2006. Evidence for increased sphingoid base 1-phosphate lyase activity in corn seedlings after prolonged exposure to fumonisin [abstract]. Toxicological Sciences 90(1):408.
Studies on the Induction of Neural Tube Defects in the Lm/bc and Cd1 Mouse Strains Following Oral Or Intraperitoneal Fumonisin Exposure - (Abstract)
Voss, K.A., Riley, R.T., Burns, T.D., Gelineau-Van Waes, J.B. 2005. Studies on the induction of neural tube defects in the lm/bc and cd1 mouse strains following oral or intraperitoneal fumonisin exposure. Proceedings of the 40th Joint Panel Meeting of the United States-Japan Cooperative Program on Natural Resources. Matusushima, Japan. p. 58
Toxicity Responses of Corn to the Mycotoxin Fumonisin B1 in the Absence of Fusarium Verticillioides Infection - (Abstract)
Zimeri, A.M., Williams, L.D., Riley, R.T., Glenn, A.E. 2005. Toxicity responses of corn to the mycotoxin fumonisin b1 in the absence of fusarium verticillioides infection [abstract]. Multicrop Aflatoxin and 6th Annual Fumonisin Elimination and Fungal Genomics Workshop-The Peanut Foundation. p. 55.
Toxic Effects of Fumonisin in Mouse Liver Are Independent of the Peroxisome Proliferator-Activated Receptor Alpha - (Peer Reviewed Journal)
Voss, K.A., Liu, J., Anderson, S.P., Dunn, C., Miller, J., Owen, J.R., Riley, R.T., Bacon, C.W., Corton, J. 2006. Toxic effects of fumonisin in mouse liver are independent of the peroxisome proliferator-activated receptor alpha. Toxicological Sciences. 89(1):108-119.
Fumonisins in Maize in Guatemala, Preliminary Exposure Estimate, and Policies and Recommendations to Minimize Exposure - (Abstract)
Riley, R.T., Torres, O.A., Palencia, E.R., Lopez De Pratdesaba, L., Glenn, A.E., O Donnell, K., Fuentes, M. 2006. Fumonisins in maize in guatemala, preliminary exposure estimate, and policies and recommendations to minimize exposure. Aflatoxin Elimination Workshop Proceedings. p. 61.
Developmental Toxicity of Fusarium Verticillioides and Fumonisin B1 in Lm/bc and Cd1 Mice: Comparing the in Vivo Models - (Abstract)
Voss, K.A., Riley, R.T., Burns, T.D., Gelineau-Van Waes, J.B. 2005. Developmental toxicity of fusarium verticillioides and fumonisin b1 in lm/bc and cd1 mice: comparing the in vivo models. Proceeding of the 2005 Annual MultiCrop Aflatoxin/Fumonisin Elimination and Fungal Genomics Workshop. Raleigh, North Carolina. p. 63.
Lupus-Prone Nzbwf1/j Mice, Defective in Cytokine Signaling, Are Resistant to Fumonisin Hepatotoxicity Despite Accumulation of Liver Sphinganine - (Peer Reviewed Journal)
Sharma, R.P., He, Q., Riley, R.T. 2005. Lupus-prone NZBWF1/J mice, defective in cytokine signaling, are resistant to fumonisin hepatotoxicity despite accumulation of liver sphinganine. Toxicology. 216:59-71.
Fumonisin Concentration and Biological Activity of Corn, Masa, and Tortilla Chips - (Peer Reviewed Journal) - (19-Jul-05)
Trends in Fumonisin Research: Recent Studies on the Developmental Effects of Fumonisins and Fusarium Verticillioides - (Review Article)
Voss, K.A., Riley, R.T., Gelineau-Van Waes, J. 2005. Trends in fumonisin research: recent studies on the developmental effects of fumonisins and fusarium verticillioides. Journal of the Japanese Association of Mycotoxicology/Mycotoxins 55(2):91-100
In Planta Interactions of Fusarium Verticillioides with Corn and Mechanisms of Fumonisin Pyhtotoxicity. - (Abstract)
Zimeri, A.M., Williams, L.D., Riley, R.T., Glenn, A.E. 2005. In planta interactions of Fusarium verticillioides with corn and mechanisms of fumonisin pyhtotoxicity [abstract]. Phytopathology. 95(6):S118.
Fumonisins in Highland and Lowland Maize in Guatemala and a Preliminary Exposure Estimate - (Abstract) - (26-May-05)
Activated Carbon Does Not Prevent the Toxicity of Culture Material Containing Fumonisin B1 When Fed to Weanling Piglets - (Peer Reviewed Journal)
Piva, A., Casadei, G., Pagliuca, G., Cabassi, E., Galvano, F., Solfrizzo, M., Riley, R.T., Diaz, D.E. 2005. Activated carbon does not prevent the toxicity of culture material containing fumonisin b1 when fed to weanling piglets. Journal of Animal Science. 83:1939-1947.
Reproductive Toxicity of Fumonisin-Producing Fusarium Verticillioides in the Lm/bc and Cd1 Mouse Strains - (Abstract)
Voss, K.A., Gelineau-Van Waes, J.B., Riley, R.T., Burns, T.D., Bacon, C.W. 2005. Reproductive toxicity of fumonisin-producing fusarium verticillioides in the LM/Bc and CD1 mouse strains. Annual Report for 2004 of the Center for Food Safety, University of Georgia. Athens, Georgia. University of Georgia. p.
Fumonisin-Induced Liver Toxicity in Mice Is Independent of the Peroxisome Proliferation-Activated Receptor Alpha - (Abstract)
Voss, K.A., Liu, J., Miller, J.D., Owen, J.R., Riley, R.T., Bacon, C.W., Corton, J.C. 2005. Fumonisin-induced liver toxicity in mice is independent of the peroxisome proliferation-activated receptor alpha. Annual Report for 2004 Center for Food Safety, University of Georgia. Athens, Georgia. University of Georgia. p.
Maternal Fumonisin Exposure and Risk for Neural Tube Defects: Disruption of Sphingolipid Metabolism and Folate Transport in An in Vivo Mouse Model. - (Peer Reviewed Journal)
Gelineau-Van Waes, J., Starr, L., Maddox, J.R., Aleman, F., Voss, K.A., Wilberding, J., Riley, R.T. 2005. Maternal fumonisin exposure and risk for neural tube defects: disruption of sphingolipid metabolism and folate transport in an in vivo mouse model. Birth Defects Part A: Clinical amd Molecular Teratology. 73:487-497.
Foodborne Mycotoxins: Chemistry, Biology, Ecology, and Toxicology - (Book/Chapter)
Cousin, M.A., Riley, R.T., Pestka, J.J. 2005. Foodborne mycotoxins: chemistry, biology, ecology, and toxicology. In: Fratamico, P.M., Bhunia, A.K., editors, Foodborne Pathogens: Microbiology and Molecular Biology. Norfolk, United Kingdom: Horizon Scientific Press, Ltd. p. 164-226.
Time and Dose-Dependent Changes in Sphingoid Base 1-Phosphates in Tissues from Rats Fed Diets Containing Fumonisins - (Abstract)
Riley, R.T., Showker, A.J., Voss, K.A. 2005. Time- and dose-dependent changes in sphingoid base 1-phosphates in tissues from rats fed diets containing fumonisins [abstract]. Toxicological Sciences. 84(S1):284-285.
Myriocin Prevents Fumonisin B1-Induced Sphingoid Base Accumulation in Mice Liver Without Ameliorating Hepatotoxicity. - (Peer Reviewed Journal)
He, Q., Riley, R.T., Sharma, R.P. 2005. Myriocin prevents fumonisin B1-induced sphingoid base accumulation in mice liver without ameliorating hepatotoxicity. Food and Chemical Toxicology. 43:969-979.
Developmental Toxicity of Diets Containing Fumonisin B1 to Lm/bc and Cd1 Mice: a Comparative Study - (Abstract)
Voss, K.A., Gelineau Van-Waes, J.B., Riley, R.T., Burns, T.D., Bacon, C.W. 2005. Developmental toxicity of diets containing fumonisin B1 to LM/BC and CD1 mice: a comparative study. Toxicological Sciences. 84:(S1):1396.
Accumulation of Sphingoid Bases and Sphingoid Base 1-Phosphates: a Possible Mechanism for Fusarium Verticillioides Corn-Seedling Disease - (Abstract)
Williams, L.D., Glenn, A.E., Bacon, C.W., Smith, M.A., Riley, R.T. 2005. Accumulation of sphingoid bases and sphingoid base 1-phosphates: a possible mechanism for Fusarium verticillioides corn-seedling disease [abstract]. Toxicological Sciences. 84(S1):285.
Fungal Secondary Metabolites As Fitness and Pathogenicity Factors: a Closer Look at Fumonisin B1. - (Abstract)
Glenn, A.E., Williams, L.D., Riley, R.T. 2005. Fungal secondary metabolites as fitness and pathogenicity factors: a closer look at fumonisin b1. Great Lakes Regional American Chemical Society Symposium.
In Vitro Screening for Biological Activity Associated with Fumonisins in Nixtamalized Foods - (Abstract)
Williams, L.D., Voss, K.A., Norred, W.P., Saunders, S., Riley, R.T. 2004. In vitro screening for biological activity associated with fumonisins in nixtamalized foods [abstract]. Toxicological Sciences. 78:1029.
Mycotoxins: Metabolism, Mechanisms and Biochemical Markers - (Book/Chapter)
Riley, R.T., Pestka, J. 2005. Mycotoxins: Metabolism, mechanisms and biochemical markers. In: Diaz, D., editor. The Mycotoxin Blue Book. Nottingham, UK:Nottingham University Press. p. 279-294.
Fumonisin B1 As a Phytotoxin of Maize: Examining Mechnaisms of Pathogenicity, Cellular Toxicity, and Resistance in Maize and Possible Translocation of Fumonisin. - (Government Publication)
Glenn, A.E., Williams, L.D., Zimeri, A.M., Riley, R.T. 2005. Fumonisin b1 as a phytotoxin of maize: examining mechnaisms of pathogenicity, cellular toxicity, and resistance in maize and possible translocation of fumonisin. Multicrop Aflatoxin and Fumonisin Elimination and Fungal Genomics Workshop-The Peanut Foundation. Symposium Proceedings. p. 13.
Maternal and Fetal Toxicity of Fumonisin-Producing Fusarium Verticillioides Culture Material in Lm/bc and Cd1 Mice. - (Abstract)
Voss, K.A., Gelineau-Van Waes, J.B., Riley, R.T., Burns, T.D., Bacon, C.W. 2004. Maternal and fetal toxicity of fumonisin-producing fusarium verticillioides culture material in lm/bc and cd1 mice. United States-Japan Cooperative Program on Development and Utililization of Natural Resources. Abstracts Proceedings.
Inhibition of Sphingolipid Biosynthesis Decreases Phosphorylated Erk2 in Llc-Pk1 Cells. - (Peer Reviewed Journal)
Rentz, S.S., Showker, A.J., Meredith, F.I., Riley, R.T. 2005. Inhibition of sphingolipid biosynthesis decreases phosphorylated ERK2 in LLC-PK1 cells. Food and Chemical Toxicology. 43:123-131.
The Fumonisin Risk Assessment and Emerging Issues - (Abstract)
Riley, R.T., Voss, K.A. 2005. The fumonisin risk assessment and emerging issues. Phytopathology. 94(6):S120.
The Fumonisin Risk Assessment - (Abstract)
Riley, R.T., Voss, K.A. 2004. The fumonisin risk assessment. Phytopathology. 94:S120.
Toxicology of the Fumonisins and Neural Rube Defects (Ntd) - (Abstract)
Riley, R.T., Gelineau-Van Waes, J., Voss, K.A., Sharma, R.P., Haschek, W.M., Constable, P.D. 2004. Toxicology of the fumonisins and neural rube defects (NTD)[abstract]. International IUPAC Symposium on Mycotoxins and Phycotoxins. p. 91.
Fumonisin Ortho-Phthalaldehyde Derivative Is Stabilized at Low Temperature - (Peer Reviewed Journal)
Williams, L.D., Meredith, F.I., Riley, R.T. 2004. Fumonisin- ortho-phthalaldehyde derivative is stabilized at low temperature. Journal of Chromatography B. 806:311-314.
Fumonisins in Maize in Guatemala and a Preliminary Estimate of Daily Intakes - (Abstract)
Riley, R.T., Palencia, E., Torres, O.R., Glenn, A.E., Fuentes, M. 2004. Fumonisins in maize in guatemala and a preliminary estimate of daily intakes. Toxicological Sciences. 78:1023
In Vitro Screening for Biological Acitivity Associated with Fumonisins in Nixtamalized Foods - (Abstract)
Williams, L.D., Voss, K.A., Norred, W.P., Saunders, D.S., Riley, R.T. 2004. In vitro screening for biological acitivity associated with fumonisins in nixtamalized foods. Toxicological Sciences. 78:1029.
Fumonisins: Update and Future Research Needs - (Abstract) - (02-Dec-03)
The Effects of Cooking on Fumonisins: Overview and Recent Studies - (Abstract)
Voss, K.A., Riley, R.T., Norred, W.P., Bacon, C.W., Meredith, F.I. 2004. The effects of cooking on fumonisins: overview and recent studies. Multicrop Aflatoxin and Fumonisin Elimination and Fungal Genomics Workshop-The Peanut Foundation. October 13-15, 2003, Savannah, Georgia. p. 19.
A Survey of Fumonisins in Maize in the Highlands and Lowlands of Guatemala 2000-2002 - (Abstract)
Riley, R.T., Torres, O.A., Palencia, E., Glenn, A.E., Fuentes, M. 2004. A survey of fumonisins in maize in the highlands and lowlands of guatemala 2000-2002. Multicrop Aflatoxin and Fumonisin Elimination and Fungal Genomics Workshop-The Peanut Foundation. October 13-15, 2003, Savannah, Georgia. p. 15.
Panel Discussion: 4th Annual Fumonisin Elimination Workshop for Multicrop Workshop-Afllatoxin/fumonisin/fungal Genomics. - (Proceedings/Symposium)
Riley, R.T. 2004. Panel discussion: 4th annual fumonisin elimination workshop for multicrop workshop-afllatoxin/fumonisin/fungal genomics.. Multicrop Aflatoxin and Fumonisin Elimination and Fungal Genomics Workshop-The Peanut Foundation. October 12-15, 2003, Savannah, Georgia. p.22-23.
Fumonisins Disrupt Shpingolipid Metabolism, Folate Transport, and Neural Tube Development in Embryo Culture and in Vivo: a Potential Risk Factor for Human Neural Tube Defects among Populations Consuming Fumonisin-Contaminated - (Peer Reviewed Journal)
Marasas, W.O., Riley, R.T., Hendricks, K.A., Stevens, V.L., Sadler, T.W., Gelineau-Van Waes, J., Missmer, S.A., Cabrera Valverde, J., Torres, O.L., Gelderblom, W.A., Allegood, J., Martinez De Figueroa, A., Maddox, J., Miller, J., Starr, L., Sullards, M., Roman Trigo, A., Voss, K.A., Wang, E., Merrill, Jr., A.H. 2004. Fumonisins disrupt shpingolipid metabolism, folate transport, and neural tube development in embryo culture and in vivo: a potential risk factor for human neural tube defects among populations consuming fumonisin-contaminated. Journal of Nutrition 134:711-716.
Fumonisins: Toxicology, Emerging Issues, and Prospects for Control and Detoxification - (Proceedings/Symposium)
Voss, K.A., Riley, R.T., Gelineau-Van Waes, J.B., Bacon, C.W. 2004. Fumonisins: toxicology, emerging issues, and prospects for control and detoxification. In: Yoshizawa, T., editor, New Horizon of Mycotoxicology for Assuring Food Safety, Proceedings International Symposium of Mycotoxicology Kagawa 2003. Takamatsu, Kagawa, Japan. p. 41-48.
Current Trends in Mycotoxin Research: Deoxynivalenol and Fumonisins - (Proceedings/Symposium)
Voss, K.A., Plattner, R.D., Gelineau-Van Waes, J.B., Riley, R.T., Bacon, C.W. 2003. Current trends in mycotoxin research: deoxynivalenol and fumonisins. National Food Research Institute's International Symposium on Food Safety (Japan). November, 1-5, 2003, Tsukuba, Japan, p. 9-12.
Fumonisins: Toxicology, Emerging Issues, and Prospects for Detoxification - (Abstract)
Voss, K.A., Riley, R.T., Gelineau-Van Waes, J.B., Bacon, C.W. 2004. Fumonisins: toxicology, emerging issues, and prospects for detoxification [abstract]. Japanese Association of Mycotoxicology - International Symposium of Mycotoxicology in Kagawa. November 4, 2003, Kagawa, Japan. p. 5.
The Use of Genetically Modified Mice for Studying the in Vivo Mode of Action of Fumonisins: Studies on Tumor Necrosis Factor Alpha and the Peroxixome Proliferator-Activated Receptor Alpha. - (Abstract)
Voss, K.A., Riley, R.T., Sharma, R.P., Corton, J., Miller, J., Bacon, C.W. 2004. The use of genetically modified mice for studying the in vivo mode of action of fumonisins: studies on tumor necrosis factor alpha and the peroxixome proliferator-activated receptor alpha. Abstracts of Proceedings of US-Japan Cooperative Program on Devlopment and Utililization of Natural Products. November 9-14, 2003. Tokyo, Japan.
Case Study: Risk Analysis of Fumonisin in "fao Risk Analysis Manual" - (Book/Chapter)
FAO: Food Safety - Risk Analysis, a manual published by the United Nations Food & Agriculture Organization, ILSI, and the Industry Council for Development.
Total Fumonisins Are Reduced in Tortillas Using the Traditional Nixtamalization Methods of Mayan Communities - (Peer Reviewed Journal)
Palencia, E., Torres, O., Hagler, W., Meredith, F.I., Williams, L.D., Riley, R.T. 2003. Total fumonisins are reduced in tortillas using the traditional nixtamalization methods of mayan communities. JOURNAL OF NUTRITION 133:3200-3203.
Method of Altering Sphingolipid Metabolism and Detecting Fumonisin Ingestion and Contamination - (Patent Application)
Merrill, Jr., A.H., Wang, E.W., Liotta, D.C., Riley, R.T. 2004. Method of altering sphingolipid metabolism and detecting fumonisin ingestion and contamination. U.S. Patent 6,720,184.
Performance and Biochemical Parameters of Weanling Pigs Consuming Contaminated Diets with Or Without the Addition of Activiated Charcoal - (Abstract)
Journal of Animal Science. Suppl. T53:116. 2003.
Fate of Fumonisin in Maize During Nixtamalization and Tortilla Production by Mayan Communities in Guatemala - (Abstract) - (15-Jan-03)
Fumonisin-Induced Neural Tube Defects: Disruption of Sphingolipids and Folate Transport - (Abstract)
Toxicologist. 2003. v.77. Abstract. p.171.
Fumonisin B1-Induced Neural Tube Defects: Disruption of Membrane Sphingolipids and Folate Transport - (Abstract)
STARR, L., RILEY, R.T., VOSS, K.A., MADDOX, J., BENNETT, G., GELINEAU-VAN WAES, J. FUMONISIN B1-INDUCED NEURAL TUBE DEFECTS: DISRUPTION OF MEMBRANE SPHINGOLIPIDS AND FOLATE TRANSPORT. TOXICOLOGIST. 2003. v.77. p.10.
Effects of Cooking on the Biological Activity of Fumonisins - (Abstract)
VOSS, K.A., NORRED, W.P., MEREDITH, F.I., RILEY, R.T., BACON, C.W., SAUNDERS, D.S. EFFECTS OF COOKING ON THE BIOLOGICAL ACTIVITY OF FUMONISINS. TOXICOLOGIST. 2003. v.77. Abstract p.252.
Subchronic Toxicity in Rats Fed Culture Materials of Fumonisin-Producing and Moniliformin-Producing Fungal Isolates - (Abstract)
OWEN, J.R., PLATTNER, R.D., ROTTINGHAUS, G.E., RILEY, R.T., VOSS, K.A. SUBCHRONIC TOXICITY IN RATS FED CULTURE MATERIALS OF FUMONISIN-PRODUCING AND MONILIFORMIN-PRODUCING FUNGAL ISOLATES. TOXICOLOGIST. 2003. v.77. p.253.
Subchronic Toxicity in Rats Fed Culture Materials of Fumonisin-Producing and Moniliformin-Producing Fungal Isolates - (Abstract)
Owen, J.R., Plattner, R.D., Rottinghaus, G.E., Riley, R.T., Tackett, R.T., Voss, K.A. 2003. Subchronic toxicity in rats fed culture materials of fumonisin-producing and moniliformin-producing fungal isolates. Toxicological Sciences. 82:253.
Effects of Cooking on the Biological Activity of Fumonisins - (Abstract)
Toxicologist. 2003. v.77. Abstract. p.252.
Inhibition of Ceramide Synthase in Corn Seedlings Infected with Fusarium Verticillioides Or Exposed Directly to Fumonisin B1 in Soil - (Abstract)
WILLIAM, L.D., GLENN, A.E., BACON, C.W., SHOWKER, A.J., RILEY, R.T. INHIBITION OF CERAMIDE SYNTHASE IN CORN SEEDLINGS INFECTED WITH FUSARIUM VERTICILLIOIDES OR EXPOSED DIRECTLY TO FUMONISIN B1 IN SOIL. TOXICOLOGIST. 2003. v.77. Abstract p.189.
Inhibition of Ceramide Synthase in Corn Seedlings Infected with Fusarium Verticillioides Or Exposed Directly to Fumonisin B1 in Soil - (Abstract)
Toxicologist. 2003. v.77. Abstract. p.189.
The Role of the Peroxisome Proliferator-Activated Receptor Alpha in Modulating the Effects of Fumonisin B1 in Mouse Liver - (Abstract)
VOSS, K.A., LAUGHTER, A., ANDERSON, A., DUNN, C., STAUBER, A.J., RILEY, R.T., MILLER, J.D., CORTON, J.C. THE ROLE OF THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA IN MODULATING THE EFFECTS OF FUMONISIN B1 IN MOUSE LIVER. TOXICOLOGIST. 2003. v.77. Abstract. p.7.
Role of the Peroxisome Proliferator-Activated Receptor Alpha in Modulating the Effects of Fumonisin B1 in Mouse Liver - (Abstract)
Toxicologist. 2003. v.77. Abstract. p.7.
Leaching and Binding of Fumonisin in Soil Microcosms - (Peer Reviewed Journal)
WILLIAM, L.D., BACON, C.W., MEREDITH, F.I., FRANZLUEBBERS, A.J., WYATT, R.D., SMITH, M.A., RILEY, R.T. LEACHING AND BINDING OF FUMONISIN IN SOIL MICROCOSMS. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 2003. v.51. p.685-690.
Kinetics and Binding of Fumonisin in a Model Soil System - (Abstract) - (01-Nov-02)
Determining the Effect of Baking, Frying and Mixtamalization on Fumonisins by Means of in Vivo and in Vitro Bioassays - (Abstract) - (20-Oct-02)
Evidence for a Fusarium Verticillioides Seedling Pathogenicity Factors: All Roads Traveled Lead to Fumonisin. - (Proceedings/Symposium)
Glenn, A.E., Williams, L.D., Riley, R.T. 2003. Evidence for a fusarium verticillioides seedling pathogenicity factors: all roads traveled lead to fumonisin. Mycopathologia. Preface.
Proceedings of the 1st Fungal Genomics, 2nd Fumonisin Elimination and 14th Aflatoxin Elimination Workshops - (Government Publication)
RILEY, R.T., ROBENS, J.F. Editors. PROCEEDINGS OF THE 1ST FUNGAL GENOMICS, 2ND FUMONISIN ELIMINATION AND 14TH AFLATOXIN ELIMINATION WORKSHOPS. AFLATOXIN ELIMINATION WORKSHOP PROCEEDINGS. USDA-Agricultural Research Service. Beltsville, MD. 2002. p.1-184.
Evidence for a Fusarium Verticillioides Seedling Pathogenicity Factor: All Roads Traveled Lead to Fumonisin. - (Abstract) - (01-Sep-02)
Characterization of a Fusarium Verticillioides Seedling Pathogenicity Factor - (Abstract) - (01-Apr-02)
The Role of Toxicology and Related Studies in Evaluating the Risk of Mycotoxins: Fumonisin B1 As An Example. - (Proceedings/Symposium)
Voss, K.A., Riley, R.T., Norred, W.P., Howard, P.C., Poling, S.M., Saunders, D.S., Meredith, F.I. 2002. The role of toxicology and related studies in evaluating the risk of mycotoxins: fumonisin b1 as an example.. Proceedings of the US Japan Joint Panel on Toxic Microorgnisms.
The Use of Chronic Toxicants by Terrorists to Disrupt the Food Supply - (Proceedings/Symposium)
RILEY, R.T. THE USE OF CHRONIC TOXICANTS BY TERRORISTS TO DISRUPT THE FOOD SUPPLY. PROCEEDINGS INTERNATIONAL LIFE SCIENCES INSTITUTE SYMPOSIUM. CD-ROM. Washington, DC. 2002.
Fumonisin B1 (Fb1) Alters Ouabain-Insensitive But Not Ouabain-Sensitive 86rb Uptake in Llc-Pk1 Cells Without Altering Membrane Permeability - (Abstract) - (01-Mar-02)
Introduction: Aflatoxin/fumonisin Elimiination and Fungal Genomics Workshops, Phoenix, Arizona - (Proceedings/Symposium)
ROBENS, J.F., RILEY, R.T. INTRODUCTION: AFLATOXIN/FUMONISIN ELIMIINATION AND FUNGAL GENOMICS WORKSHOPS, PHOENIX, ARIZONA. MYCOPATHOLOGIA. 2002. v.155. p.1-3.
Special Issue - Aflatoxin/fumonisin Elimination and Fungal Genomics Workshops; Phoenix Arizona, Jane Robens and Ronald T. Riley, EDS., October 23-26, 2001 - (Proceedings/Symposium)
Mycopathologia. 2002. v.155. p.1-123.
The Role of Toxicology and Related Studies in Evaluating the Risk of Mycotoxins: Fumonisin B1 As An Example - (Abstract) - (01-Feb-02)
Instability of N-Acetylated Fumonisin B1 (Fa1) and the Impact on Inhibition of Ceramide Synthase in Rat Liver Slices - (Abstract)
NORRED, W.P., RILEY, R.T., MEREDITH, F.I., POLING, S.M., PLATTNER, R.D. INSTABILITY OF N-ACETYLATED FUMONISIN B1 (FA1) AND THE IMPACT ON INHIBITION OF CERAMIDE SYNTHASE IN RAT LIVER SLICES. MYCOPATHOLOGIA. 2002. v.155. Abstract p.35.
Inhibition of DE Novo Sphingolipid Biosynthesis Reduces Expression of P42 Map Kinase (Erk2) in Llc-Pk1 Cells - (Abstract)
RENTZ, S.S., SHOWKER, A.J., MEREDITH, F.I., RILEY, R.T. INHIBITION OF DE NOVO SPHINGOLIPID BIOSYNTHESIS REDUCES EXPRESSION OF P42 MAP KINASE (ERK2) IN LLC-PK1 CELLS. MYCOPATHOLOGIA. 2002. v.155. Abstract p.39.
Fumonisin B1 Promotes Aflatoxin B1 and N-Methyl-N'-Nitro-Nitrosoguanidine Initiated Liver Tumors in Rainbow Trout - (Abstract)
CARLSON, D.B., WILLIAMS, D.E., SPITSBERGEN, J.M., ROSS, P.F., BACON, C.W., MEREDITH, F.I., RILEY, R.T. FUMONISIN B1 PROMOTES AFLATOXIN B1 AND N-METHYL-N'-NITRO-NITROSOGUANIDINE INITIATED LIVER TUMORS IN RAINBOW TROUT. MYCOPATHOLOGIA. 2002. v.155. Abstract p.38.
Kinetics and Binding of Fumonisin in a Model Soil System - (Abstract)
WILLIAM, L.D., SHOWKER, A.J., BACON, C.W., SMITH, M.A., WYATT, R.D., MEREDITH, F.I., RILEY, R.T. KINETICS AND BINDING OF FUMONISIN IN A MODEL SOIL SYSTEM. MYCOPATHOLOGIA. 2002. v.155. Abstract p.40.
The Use of Chronic Toxicants by Terrrorists to Disrupt the Food Supply - (Abstract) - (01-Nov-01)

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