Projects

STRATEGIES TO CONTROL AND PREVENT BACTERIAL INFECTIONS IN SWINE Appropriated (D)   Accession Number: 421211

COMPARISON OF PORCINE HIGH FEVER DISEASE ISOLATES OF PRRSV TO US ISOLATES FOR THEIR ABILITY TO CAUSE SECONDARY BACTERIAL INFECTION IN SWINE Reimbursable (R)   Accession Number: 422165

H1N1 INFLUENZA A VIRUS IN SWINE SUPPLEMENTAL RESEARCH PROGRAM Other (X)   Accession Number: 418864

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Cross-reactive immune responses following vaccination with a live-attenuated influenza virus compared to adjuvanted, whole-inactivated virus in pigs - (Abstract Only)

Loving, C.L., Braucher, D.R., Brockmeier, S.L., Vincent, A.L. 2012. Cross-reactive immune responses following vaccination with a live-attenuated influenza virus compared to adjuvanted, whole-inactivated virus in pigs. Immunological Mechanisms of Vaccination, Keystone Symposia. Paper No. 2038.

Pathogenesis of HP-PRRSV in gnotobiotic pigs - (Abstract Only)

Lager, K.M., Faaberg, K.S., Brockmeier, S.L., Miller, L.C., Kappes, M.A., Spear, A., Kehrli, Jr., M.E. 2012. Pathogenesis of HP-PRRSV in gnotobiotic pigs. 2012 International PRRS Symposium. p. 92.

Comparison of the pathogenesis of Asian highly-pathogenic PRRSV isolates to U.S. isolates and their ability to cause secondary bacterial infection in swine - (Abstract Only)

Brockmeier, S.L., Loving, C.L., Palmer, M.V., Spear, A.R., Faaberg, K.S., Nicholson, T.L. 2012. Comparison of the pathogenesis of Asian highly-pathogenic PRRSV isolates to U.S. isolates and their ability to cause secondary bacterial infection in swine. International PRRS Symposium 2012. Poster No. 64.

Changes in circulating and thymic lymphocyte populations following infection with strains of North American or highly pathogenic PRRSV - (Abstract Only)

Loving, C.L., Brockmeier, S.L., Palmer, M.V., Spear, A.R., Faaberg, K.S., Nicholson, T.L. 2012. Changes in circulating and thymic lymphocyte populations following infection with strains of North American or highly pathogenic PRRSV. International PRRS Symposium 2012. Poster No. 77.

Comparison of Asian highly-pathogenic PRRSV isolates to US isolates for their ability to cause secondary bacterial infection in swine - (Abstract Only)

Brockmeier, S.L., Loving, C.L., Palmer, M.V., Spear, A.R., Faaberg, K.S., Nicholson, T.L. 2012. Comparison of Asian highly-pathogenic PRRSV isolates to US isolates for their ability to cause secondary bacterial infection in swine. Conference of Research Workers in Animal Diseases. Paper No. 184.

Changes in circulating and thymic lymphocyte populations following infection with strains of North American or highly pathogenic PRRSV - (Abstract Only)

Loving, C.L., Brockmeier, S.L., Palmer, M.V., Spear, A.R., Faaberg, K.S., Nicholson, T.L. 2012. Changes in circulating and thymic lymphocyte populations following infection with strains of North American or highly pathogenic PRRSV. Conference of Research Workers in Animal Diseases Annual Meeting. Paper No. 185.

Infection of United States swine with a Chinese highly pathogenic strain of porcine reproductive and respiratory syndrome virus - (Peer Reviewed Journal)

Guo, B., Lager, K.M., Henningson, J.N., Miller, L.C., Schlink, S.N., Kappes, M.A., Kehrli, Jr., M.E., Brockmeier, S.L., Nicholson, T.L., Yang, H., Faaberg, K.S. 2013. Experimental infection of United States swine with a Chinese highly pathogenic strain of porcine reproductive and respiratory syndrome virus. Virology. 435(2):372-384.

Biotherapeutics as alternatives to antibiotics: Effects of adenoviral delivered cytokines on innate and adaptive immunity - (Abstract Only) - (12-Sep-12)

Genomic sequence and virulence comparison of four type 2 porcine reproductive and respiratory syndrome virus strains - (Peer Reviewed Journal)

Brockmeier, S.L., Loving, C.L., Vorwald, A.C., Kehrli, Jr., M.E., Baker, R.B., Nicholson, T.L., Lager, K.M., Miller, L.C., Faaberg, K.S. 2012. Genomic sequence and virulence comparison of four Type 2 porcine reproductive and respiratory syndrome virus strains. Virus Research. 169(1):212-221.

Biotherapeutics as alternatives to antibiotics: effects of IFN-a and G-CSF on innate and adaptive immunity in swine - (Abstract Only) - (16-Jun-12)

Comparison of human-like H1 (delta-cluster) influenza A viruses in the swine host - (Peer Reviewed Journal)

Ciacci Zanella, J.R., Vincent, A.L., Zanella, E.L., Lorusso, A., Loving, C.L., Brockmeier, S.L., Gauger, P.C., Janke, B.H., Gramer, M.R. 2012. Comparison of human-like H1 (delta-cluster) influenza A viruses in the swine host. Influenza Research and Treatment. Available: http://www.hindawi.com/journals/irt/2012/329029/.

Influenza A virus and secondary bacterial infection in swine - (Abstract Only) - (02-Apr-12)

The presence of alpha interferon at the time of infection alters the innate and adaptive immune responses to porcine reproductive and respiratory syndrome virus - (Peer Reviewed Journal)

Brockmeier, S.L., Loving, C.L., Nelson, E.A., Miller, L.C., Nicholson, T.L., Register, K.B., Grubman, M.J., Brough, D.E., Kehrli, Jr., M.E. 2012. The presence of alpha interferon at the time of infection alters the innate and adaptive immune responses to porcine reproductive and respiratory syndrome virus. Clinical and Vaccine Immunology. 19(4):508-514.

Effects of interferon-alpha on the immune response to porcine reproductive and respiratory syndrome virus - (Peer Reviewed Journal) - (01-Jan-12)

Phenotypic modulation of the Bvg+ phase is not required for pathogenesis and transmission of Bordetella bronchiseptica in swine - (Peer Reviewed Journal)

Nicholson, T.L., Brockmeier, S.L., Loving, C.L., Register, K.B., Kehrli, Jr., M.E., Stibitz, S.E., Shore, S.M. 2012. Phenotypic modulation of the virulent Bvg phase is not required for pathogenesis and transmission of Bordetella bronchiseptica in swine. Infection and Immunity. 80(3):1025-1036.

Influenza A virus in pigs – protection, provocation and predisposition - (Abstract Only) - (13-Oct-11)

Enhancement of innate immunity with granulocyte colony-stimulating factor did not prevent disease in pigs infected with a highly pathogenic Chinese PRRSV strain - (Abstract Only)

Schlink, S.N., Lager, K.M., Brockmeier, S.L., Loving, C.L., Henningson, J.N., Faaberg, K.S., Guo, B., Miller, L.C., Vorwald, A.C., Kehrli, Jr., M.E. 2011. Enhancement of innate immunity with granulocyte colony-stimulating factor did not prevent disease in pigs infected with a highly pathogenic Chinese PRRSV strain. 2011 International PRRS Symposium. Paper No. 59. page 76.

Sequence and virulence comparison of four North American isolates of porcine reproductive and respiratory syndrome virus - (Abstract Only)

Brockmeier, S.L., Loving, C.L., Miller, L.C., Vorwald, A.C., Kehrli, Jr., M.E., Baker, R.B., Nicholson, T.L., Lager, K.M., Faaberg, K.S. 2011. Sequence and virulence comparison of four North American isolates of porcine reproductive and respiratory syndrome virus. Conference of Research Workers in Diseases. Paper No. 174. p. 171.

Fulminant sepsis is a cardinal sign of HP-PRRSV in pigs - (Abstract Only)

Lager, K.M., Faaberg, K.S., Guo, B., Brockmeier, S.L., Henningson, J.N., Schlink, S.N., Miller, L.C., Kappes, M.A., Kehrli, Jr., M.E., Nicholson, T.L., Yang, H.-C. 2011. Fulminant sepsis is a cardinal sign of HP-PRRSV in pigs [abstract]. 2011 International PRRS Symposium. Paper No. 60. page 77.

Host response to secondary bacterial infection associated with antecedent influenza virus infection in pigs – exacerbation associated with vaccination - (Abstract Only)

Loving, C.L., Vincent, A.L., Brockmeier, S.L., Henningson, J.N., Braucher, D.R., De Souza Rajao, D. 2011. Host response to secondary bacterial infection associated with antecedent influenza virus infection in pigs - exacerbation associated with vaccination [abstract]. Autumn Immunology Conference. Poster No. 140.

Comparison of the pathogenicity of Chinese and low virulent US porcine reproductive and respiratory syndrome viruses - (Abstract Only)

Henningson, J.N., Faaberg, K.S., Guo, B., Schlink, S.N., Miller, L.C., Kappes, M.A., Kehrli, Jr., M.E., Brockmeier, S.L., Nicholson, T.L., Vorwald, A.C., Lager, K.M. 2011. Comparison of the pathogenicity of Chinese and low virulent US porcine reproductive and respiratory syndrome viruses [abstract]. American College of Veterinary Pathologists. Paper No. 164. Veterinary Pathology. 48(6):E30.

Bordetellosis - (Book / Chapter)

Brockmeier, S.L., Register, K.B., Nicholson, T.L., Loving, C.L. 2012. Bordetellosis. In: Zimmerman, J., Karriker, L., Ramirez, A., Schwartz, K., Stevenson, G., editors.Diseases of Swine. 10th edition. Ames, IA: Iowa State University Press. pp. 670-679.

Pasteurellosis - (Book / Chapter) - (04-Jun-11)

Highly pathogenic porcine reproductive and respiratory syndrome virus JXwn06 causes high mortality in vivo - (Abstract Only)

Kappes, M.A., Guo, B., Lager, K.M., Henningson, J.N., Schlink, S.N., Miller, L.C., Brockmeier, S., Kehrli, Jr., M.E., Yang, H., Faaberg, K.S. 2011. Highly pathogenic porcine reproductive and respiratory syndrome virus JXwn06 causes high mortality in vivo [abstract]. XIIth International Nidovirus Symposium. p. 80.

Highly pathogenic Chinese porcine reproductive and respiratory syndrome virus strain JXwn06 in US swine - (Abstract Only)

Kappes, M.A., Guo, B., Lager, K.M., Henningson, J.N., Schlink, S.N., Miller, L.C., Brockmeier, S., Kehrli, Jr., M.E., Yang, H., Faaberg, K.S. 2011. Highly pathogenic Chinese porcine reproductive and respiratory syndrome virus strain JXwn06 in US swine [abstract]. 30th Annual Meeting of the American Society for Virology. p. 211.

HP-PRRSV challenge of 4 and 10-week-old pigs - (Proceedings)

Lager, K.M., Faaberg, K.S., Guo, B., Brockmeier, S., Henningson, J.N., Schlink, S.N., Miller, L.C., Kappes, M.A., Kehrli, Jr., M.E., Loving, C.L., Nicholson, T.L., Yang, H.C. 2011. HP-PRRSV challenge of 4 and 10-week-old pigs. In: Proceedings of the 5th Asian PRRSpective Symposium, May 10, 2011, Bangkok, Thailand. 6 pages.

Porcine TLR3 characterization and expression in response to influenza virus and Bordetella bronchiseptica - (Peer Reviewed Journal)

Sacco, R.E., Nicholson, T.L., Waters, T.E., Brockmeier, S. 2011. Porcine TLR3 characterization and expression in response to influenza virus and Bordetella bronchiseptica. Veterinary Immunology and Immunopathology. 142(1-2):57-63.

Contribution of Bordetella bronchiseptica Type III secretion system to respiratory disease in swine - (Abstract Only)

Brockmeier, S., Nicholson, T.L., Loving, C.L., Register, K.B. 2011. Contribution of Bordetella bronchiseptica type III secretion system to respiratory disease in swine [abstract]. American Society for Microbiology 2011 Annual Meeting. Abstract No. 1494.

Porcine circovirus type 2 (PCV2) vaccination is effective in reducing disease and PCV2 shedding in semen of boars concurrently infected with PCV2 and Mycoplasma hyopneumoniae - (Peer Reviewed Journal)

Opriessnig, T., Madson, D.M., Schalk, S., Brockmeier, S., Shen, H., Beach, N.M., Meng, X.J., Baker, R.B., Zanella, E.L., Halbur, P.G. 2011. Porcine circovirus type 2 (PCV2) vaccination is effective in reducing disease and PCV2 shedding in semen of boars concurrently infected with PCV2 and Mycoplasma hyopneumoniae. Theriogenology. 76(2):351-360.

Utility of a Panviral Microarray for Detection of Swine Respiratory Viruses in Clinical Samples - (Peer Reviewed Journal)

Nicholson, T.L., Kukielka, D., Vincent, A.L., Brockmeier, S.L., Miller, L.C., Faaberg, K.S. 2011. Utility of a panviral microarray for detection of swine respiratory viruses in clinical samples. Journal of Clinical Microbiology. 49(4):1542-1548.

Analysis of Chinese PRRSV Type 2 strain in U.S. swine - (Abstract Only)

Faaberg, K.S., Guo, B., Lager, K.M., Brockmeier, S.L., Henningson, J.N., Schlink, S.N., Miller, L.C., Yang, H. 2011. Analysis of Chinese porcine reproductive and respiratory syndrome virus type 2 strain in United States swine [abstract]. ASM Conference on Viral Genome Replication. Poster No. 55A. p. 69.

Innate immune responses to pathogens involved in the porcine respiratory disease complex - (Abstract Only)

Brockmeier, S.L., Loving, C.L., Vincent, A.L. 2011. Innate immune responses to pathogens involved in the porcine respiratory disease complex [abstract]. Keystone Symposia, Immunity in the Respiratory Tract. Poster No. 114. p. 149.

Innate Immune Responses are Enhanced in Pigs After Sequential Infection with Influenza Virus and Haemophilus parasuis - (Abstract Only)

Loving, C.L., Brockmeier, S.L., Vincent, A.L. 2010. Innate immune responses are enhanced in pigs after sequential infection with influenza virus and Haemophilus parasuis [abstract]. Conference of Research Workers in Animal Diseases. Paper No. 165.

G-CSF Analogue Treatment Increases Peripheral Neutrophil Numbers in Pigs - a Potential Alternative for In-Feed Antibiotics - (Abstract Only)

Loving, C.L., Brockmeier, S.L., Bayles, D.O., Greenlee, J.J., Lager, K.M., Kehrli, Jr., M.E. 2010. G-CSF analogue treatment increases peripheral neutrophil numbers in pigs - a potential alternative for in-feed antibiotics. Conference of Research Workers in Animal Diseases. Paper No. 140.

Analysis of Asian PRRSV Type 2 Strains - (Abstract Only)

Guo, B., Lager, K.M., Henningson, J.N., Schlink, S.N., Miller, L.C., Brockmeier, S., Yang, H.C., Faaberg, K.S. 2010. Analysis of Asian PRRSV type 2 strains [abstract]. 45th US-Japan Cooperative Program in Natural Resources Panel of Animal and Avian Health Meeting. p. 8.

Use of an Avirulent Isolate of Haemophilus parasuis as a Vaccine - (Abstract Only)

Brockmeier, S., Register, K.B., Loving, C.L., Nicholson, T.L. 2010. Use of an avirulent Isolate of Haemophilus parasuis as a vaccine. 45th US-Japan Cooperative Program in Natural Resources Panel of Animal and Avian Health Meeting. p 14.

Influenza Vaccination in the Face of Maternal Antibody Results in Enhanced Pneumonia Following Heterologous, Homosubtypic Influenza Challenge - (Abstract Only)

Loving, C.L., Brockmeier, S.L., Vincent, A.L., Gauger, P.C., Kehrli, Jr., M.E. 2010. Influenza vaccination in the face of maternal antibody results in enhanced pneumonia following heterologous, homosubtypic influenza challenge [abstract]. Keystone Symposia, Immunological Mechanisms of Vaccination. Paper No. 243.

Influenza Virus Coinfection with Bordetella bronchiseptica Enhances Bacterial Colonization and Host Responses Exacerbating Pulmonary Lesions - (Peer Reviewed Journal)

Loving, C.L., Brockmeier, S.L., Vincent, A.L., Palmer, M.V., Sacco, R.E., Nicholson, T.L. 2010. Influenza Virus Coinfection with Bordetella bronchiseptica Enhances Bacterial Colonization and Host Responses Exacerbating Pulmonary Lesions. Microbial Pathogenesis. 49(5):237-245.

Prior Colonization with an Avirulent Haemophilus parasuis Isolate Prevents Disease from a Subsequent Virulent Challenge with a Heterologous Isolate - (Proceedings)

Brockmeier, S., Loving, C.L., Mullins, M., Register, K.B., Nicholson, T.L. Prior Colonization with an Avirulent Haemophilus parasuis Isolate Prevents Disease from a Subsequent Virulent Challenge with a Heterologous Isolate. In: Proceedings of the Pig Veterinary Society International Congress, July 18-21, Vancouver, Canada. p. 192.

Prior Swine Influenza Virus Infection Enhances Pulmonary Responses to Secondary Haemophilus parasuis Infection - (Proceedings)

Loving, C.L., Brockmeier, S., Vincent, A.L. 2010. Prior Swine Influenza Virus Infection Enhances Pulmonary Responses to Secondary Haemophilus parasuis Infection. In: Proceedings of the Pig Veterinary Society International Congress, July 18-21, 2010, Vancouver, Canada. p. 264.

Human-Like H1 (Delta-Cluster) Swine Influenza Virus (SIV) Can Efficiently Replicate, Transmit, Cause Lung Pathology and Induce Humoral Immune Responses in the Swine Host - (Proceedings)

Ciacci Zanella, J.R., Vincent, A.L., Zanella, E.L., Brockmeier, S. 2010. Human-Like H1 (Delta-Cluster) Swine Influenza Virus (SIV) Can Efficiently Replicate, Transmit, Cause Lung Pathology and Induce Humoral Immune Responses in the Swine Host. In: Proceedings of the International Pig Veterinary Society Congress, July 18-21, 2010, Vancouver, Canada. p. 262.

PCV2 Vaccination Prevented Clinical PCVAD and Reduced PCV2 Viremia and Semen Shedding in Boars Concurrently Infected with PCV2b and Mycoplasma hyopneumoiae - (Proceedings)

Opriessnig, T., Madsen, D.M., Shen, H., Brockmeier, S., Beach, N., Meng, X.J. 2010. PCV2 Vaccination Prevented Clinical PCVAD and Reduced PCV2 Viremia and Semen Shedding in Boars Concurrently Infected with PCV2b and Mycoplasma hyopneumoiae. In: Proceedings of the Pig Veterinary Society International Congress, July 18-21, 2010, Vancouver, Canada. p. 427.

Contribution of the Bordetella Bps Polysaccharide to Biofilm Formation and Respiratory Disease in Swine - (Abstract Only)

Nicholson, T.L., Brockmeier, S., Loving, C.L., Lu, H., Sloan, G.P., Deora, R. 2010. Contribution of the Bordetella Bps Polysaccharide to Biofilm Formation and Respiratory Disease in Swine [abstract]. American Society for Microbiology. p. 123.

Antecedent Influenza Virus Infection Enhances Pulmonary Responses to Secondary Haemophilus Infection in a Porcine Co-Infection Model - (Abstract Only)

Loving, C.L., Brockmeier, S.L., Vincent, A.L. 2010. Antecedent Influenza virus infection enhances pulmonary responses to secondary Haemophilus infection in a porcine co-infection model [abstract]. American Association of Immunologists. Paper No. 803219.

Swine influenza virus co-infection with Bordetella bronchiseptica enhances bacterial colonization and host immune responses exacerbating pulmonary lesions - (Abstract Only)

Loving, C.L., Brockmeier, S.L., Vincent, A.L., Palmer, M.V., Sacco, R.E., Nicholson, T.L. 2010. Swine influenza virus co-infection with Bordetella bronchiseptica enhances bacterial colonization and host immune responses exacerbating pulmonary lesions [abstract]. Conference Research Workers Disease Meeting. Paper No. 130.

Studies of pathogenesis, transmission, heterologous protection, and genomics of four isolates of Haemophilus parasuis - (Abstract Only)

Brockmeier, S., Loving, C.L., Register, K.B., Nicholson, T.L., Bayles, D.O., Phillips, G.J. 2009. Studies of pathogenesis, transmission, heterologous protection, and genomics of four isolates of Haemophilus parasuis [abstract]. 2009 Conference of Research Workers in Diseases. Abstract No. 15, p. 118.

Studies of Pathogenesis, Transmission, and Heterologous Protection of Four Isolates of Haemophilus parasuis in a Highly Susceptible Swine Population - (Abstract Only)

Brockmeier, S., Loving, C.L., Register, K.B., Nicholson, T.L., Bayles, D.O., Phillips, G.J. 2010. Studies of pathogenesis, transmission, and heterologous protection of four isolates of Haemophilus parasuis in a highly susceptible swine population [abstract]. 2010 American Association of Swine Veterinarians Annual Meeting. p. 127-129.

Microarray and functional analysis of growth-phase dependent gene regulation in Bordetella bronchiseptica - (Peer Reviewed Journal)

Nicholson, T.L., Buboltz, A.M., Harvill, E.T., Brockmeier, S.L. 2009. Microarray and Functional Analysis of Growth-Phase Dependent Gene Regulation in Bordetella bronchiseptica. Infection and Immunity. 77(10):4221-4231.

Characterization and comparative analysis of the genes encoding Haemophilus parasuis outer membrane proteins P2 and P5 - (Peer Reviewed Journal)

Mullins, M.A., Register, K.B., Bayles, D.O., Loving, C.L., Nicholson, T.L., Brockmeier, S.L., Dyer, D.W., Phillips, G.J. 2009. Characterization and Comparative Analysis of the Genes Encoding Haemophilus parasuis Outer Membrane Proteins P2 and P5. Journal of Bacteriology. 191(19):5988-6002.

Identification and Comparative Analysis of Genes Encoding Outer Membrane Proteins P2 and P5 in Haemophilus parsuis - (Abstract Only)

Mullins, M.A., Register, K.B., Bayles, D.O., Loving, C.L., Nicholson, T.L., Brockmeier, S.L., Dyer, D.W., Phillips, G.J. 2009. Identification and comparative analysis of genes encoding outer membrane proteins P2 and P5 in Haemophilus parsuis [abstract]. 109th American Society for Microbiology General Meeting. Poster No. Z-034.

Contribution of Bordetella bronchiseptica Filamentous Hemagglutinin and Pertactin to Respiratory Disease in Swine - (Peer Reviewed Journal)

Nicholson, T.L., Brockmeier, S., Loving, C.L. 2009. Contribution of Bordetella bronchiseptica Filamentous Hemagglutinin and Pertactin to Respiratory Disease in Swine. Infection and Immunity. 77(5):2136-2146.

Adenovirus-Mediated Expression of Interferon-Alpha Delays Viral Replication and Reduces Disease Signs in Swine Challenged with Porcine Reproductive and Respiratory Syndrome Virus - (Peer Reviewed Journal)

Brockmeier, S., Lager, K.M., Grubman, M.J., Brough, D.E., Ettyreddy, D., Sacco, R.E., Gauger, P.C., Loving, C.L., Vorwald, A.C., Kehrli Jr, M.E., Lehmkuhl, H.D. 2009. Adenovirus-Mediated Expression of Interferon-Alpha Delays Viral Replication and Reduces Disease Signs in Swine Challenged with Porcine Reproductive and Respiratory Syndrome Virus. Viral Immunology. 22(3):173-180.

Differences in immune response of pigs challenged with a high versus low dose inoculum of porcine reproductive and respiratory syndrome virus - (Peer Reviewed Journal)

Loving, C.L., Brockmeier, S.L., Vincent, A.L., Lager, K.M., Sacco, R.E. 2008. Differences in clinical disease and immune response of pigs challenged with a high-dose versus low-dose inoculum of porcine reproductive and respiratory syndrome virus. Viral Immunology. 21(3):315-325.

Investigating the porcine immune reponse to Haemophilus parasuis - (Abstract Only) - (15-May-08)

Early Induction of Cytokines in Pigs Coinfected with Swine Influenza Virus and Bordetella bronchiseptica - (Proceedings)

Brockmeier, S., Vincent, A.L., Loving, C.L., Nicholson, T.L., Sacco, R.E. 2008. Early Induction of Cytokines in Pigs Coinfected with Swine Influenza Virus and Bordetella bronchiseptica. In: Proceedings of the 20th International Pig Veterinary Society Congress, June 22-26, 2008, Durban, South Africa. 1:10.

Early Induction of Cytokines in Pigs Coinfected with Swine Influenza Virus and Bordetella bronchiseptica - (Abstract Only)

Brockmeier, S., Loving, C.L., Nicholson, T.L., Vincent, A.L., Sacco, R.E. 2008. Early Induction of Cytokines in Pigs Coinfected with Swine Influenza Virus and Bordetella bronchiseptica [abstract]. American Society for Microbiology Meeting, June 2-4, 2008, Boston, Massachusetts. 2008 CDROM.

Contribution of Bordetella bronchiseptica Filamentous Hemagglutinin and Pertactin to Respiratory Disease in Swine - (Abstract Only)

Nicholson, T.L., Brockmeier, S., Loving, C.L. 2008. Contribution of Bordetella bronchiseptica Filamentous Hemagglutinin and Pertactin to Respiratory Disease in Swine [abstract]. American Society for Microbiology Meeting, June 2-4, 2008, Boston, Massachusetts. 2008 CDROM.

Bordetella bronchiseptica Bvg Phase-Dependent Contribution to Colonization, Transmission, and Immune Responses in Pigs - (Abstract Only)

Loving, C.L., Nicholson, T.L., Brockmeier, S. 2008. Bordetella bronchiseptica Bvg Phase-Dependent Contribution to Colonization, Transmission, and Immune Responses in Pigs [abstract]. American Society for Microbiology Meeting, June 2-4, 2008, Boston, Massachusetts. 2008 CDROM.

Coinfection of Pigs with Swine Influenza Virus and Bordetella bronchiseptica - (Abstract Only)

Brockmeier, S., Vincent, A.L., Nicholson, T.L., Sacco, R.E., Palmer, M.V. 2007. Coinfection of Pigs with Swine Influenza Virus and Bordetella bronchiseptica [abstract]. In: United States Japan Natural Resources Animal and Avian Health Panel, December 5, 2007, Tsukuba, Japan. p. 25.

Growth Phase dependent gene regulation in Bordetella bronchiseptica - (Abstract Only) - (12-Nov-07)

Detection of respiratory pathogens in aerosols from acutely infected pigs - (Peer Reviewed Journal)

Hermann, J.R., Brockmeier, S., Zimmerman, J.J. 2008. Detection of respiratory pathogens in aerosols from acutely infected pigs. Canadian Journal of Veterinary Research. 72(4):367-370.

Coinfection of pigs with Porcine Respiratory Coronavirus and Bordetella bronchisphica - (Peer Reviewed Journal)

Brockmeier, S., Loving, C.L., Nicholson, T.L., Palmer, M.V. 2008. Coinfection of pigs with Porcine Respiratory Coronavirus and Bordetella bronchisphica. Veterinary Microbiology. 128(1-2):36-47.

Expression of the dermonecrotic toxin by Bordetella bronchiseptica is not necessary for predisposing to infection with toxigenic Pasteurella multocida - (Peer Reviewed Journal)

Brockmeier, S., Register, K.B. 2007. Expression of the dermonecrotic toxin by Bordetella bronchiseptica is not necessary for predisposing to infection with toxigenic Pasteurella multocida. Veterinary Microbiology. 125(3-4):284-289.

Immune response in mice and swine to DNA vaccines derived from the Pasteurella multocida toxin gene - (Peer Reviewed Journal)

Register, K.B., Sacco, R.E., Brockmeier, S. 2007. Immune response in mice and swine to DNA vaccines derived from the Pasteurella multocida toxin gene. Vaccine. 25(32):6118-28.

Coinfection with Swine Influenza Virus and Bordetella bronchiseptica in Pigs - (Abstract Only)

Brockmeier, S., Vincent, A.L., Sacco, R.E., Nicholson, T.L., Palmer, M.V. 2007. Coinfection with Swine Influenza Virus and Bordetella bronchiseptica in Pigs [abstract]. American Society for Microbiology Meeting, May 21-25,2007, Toronto, Canada. 2007 CD-ROM.

Immune Response in Mice and Swine to a DNA Vaccine Derived from the Pasteurella multocida toxin gene - (Abstract Only)

Register, K.B., Sacco, R.E., Brockmeier, S. 2007. Immune Response in Mice and Swine to a DNA Vaccine Derived from the Pasteurella multocida toxin gene[abstract]. American Society for Microbiology Meeting. May 21-25, 2007, Toronto, Canada. 2007 CD-ROM.

INNATE CYTOKINE RESPONSES IN PORCINE MACROPHAGE POPULATIONS: EVIDENCE FOR DIFFERENTIAL RECONGITION OF DSRNA - (Peer Reviewed Journal)

Loving, C.L., Brockmeier, S., Wenjun, M., Richt, J., Sacco, R.E. 2006. Innate Cytokine Responses in Porcine Macrophage Populations: Evidence for Differential Recongition of dsRNA. Journal of Immunology. 177:8432-8439.

Expression Profiling of Bordetella Bronchiseptica Responses to Temperature Using a Long-Oligonucleotide Microarray - (Abstract Only)

Nicholson, T.L., Brockmeier, S., Register, K.B. 2006. Expression Profiling of Bordetella Bronchiseptica Responses to Temperature Using a Long-Oligonucleotide Microarray [abstract]. United States-Japan Cooperative Program in Natural Resources. p. 18.

Differential type I interferon activation and susceptibility of dendritic cell populations to porcine arterivirus - (Peer Reviewed Journal)

Loving, C.L., Brockmeier, S., Sacco, R.E. 2006. Differential type I interferon activation and susceptibility of dendritic cell populations to porcine arterivirus. Immunology. 120:217-229.

Presence of interferon-alpha delays viral replication and reduces disease signs in pigs challenged with porcine reproductive and respiratory syndrome virus - (Abstract Only)

Brockmeier, S.L., Lager, K.M., Grubman, M.J., Brough, D., Ettyreddy, D., Sacco, R.E., Gauger, P.C., Lehmkuhl, H.D. 2006. Presence of interferon-alpha delays viral replication and reduces disease signs in pigs challenged with porcine reproductive and respiratory syndrome virus. Proceedings of the 87th Conference of Research Workers in Animal Diseases, December 3-5, 2006. Chicago, Illinois. p.124.

Presence of interferon-alpha delays viral replication and reduces disease signs in pigs challenged with porcine reproductive and respiratory syndrome virus - (Abstract Only)

Brockmeier, S.L., Lager, K.M., Grubman, M.J., Brough, D., Ettyreddy, D., Sacco, R.E., Gauger, P.C., Lehmkuhl, H.D. 2006. Presence of interferon-alpha delays viral replication and reduces disease signs in pigs challenged with porcine reproductive and respiratory syndrome virus. Proceeding of the International PRRS Symposium, December 1-2, 2006, Chicago, Illinois. p. 27.

DIFFERENTIAL REGULATION OF TYPE I INTERFERON ACTIVATION IN MACROPHAGES - (Abstract Only)

Loving, C.L., Brockmeier, S., Sacco, R.E. 2006. Differential regulation of type I interferon activation in macrophages [abstract]. American Association of Immunologists Proceedings. 249:43-44.

PULMONARY DENDRITIC CELLS ISOLATED FROM NEONATAL AND ADULT OVINE LUNG TISSUE - (Peer Reviewed Journal)

Fach, S.J., Brockmeier, S., Hobbs, L.A., Lehmkuhl, H.D., Sacco, R.E. 2006. Pulmonary dendritic cells isolated from neonatal and adult ovine lung tissue. Veterinary Immunology and Immunopathology. 112(3-4):171-82.

COINFECTION WITH PORCINE RESPIRATORY CORONAVIRUS AND BORDETELLA BRONCHISEPTICA IN PIGS - (Abstract Only)

Brockmeier, S., Loving, C.L., Nicholson, T.L., Palmer, M.V. 2005. Coinfection with porcine respiratory coronavirus and bordetella bronchiseptica in pigs. American Society for Microbiology. Z016, p. 614.

EXPRESSION PROFILING OF BORDETELLA BRONCHISEPTICA RESPONSES TO TEMPERATURE USING A LONG-OLIGONUCLEOTIDE MICROARRAY - (Abstract Only)

Nicholson, T.L., Brockmeier, S., Register, K.B. 2005. Expression profiling of bordetella bronchiseptica responses to temperature using a long-oligonucleotide microarray. American Society for Microbiology. D118, p. 218.

EXPRESSION PROFILING OF BORDETELLA BRONCHISEPTICA RESPONSES TO TEMPERATURE USING A LONG-OLIGONUCLEOTIDE MICROARRAY - (Abstract Only)

Nicholson, T.L., Brockmeier, S., Register, K.B. 2005. Expression profiling of Bordetella bronchiseptica responses to temperature using a long-oligonucleotide microarray [abstract]. International Union of Microbiological Societies Proceedings/Abstracts. p. 18.

PRRS VIRUS PRODUCTIVELY INFECTS MONOCYTE-DERIVED DENDRITIC CELLS AND INDUCES PRODUCTION OF INNATE ANTIVIRAL MEDIATORS - (Abstract Only)

Loving, C.L., Brockmeier, S., Sacco, R.E. 2005. Prrs virus productively infects monocyte-derived dendritic cells and induces production of innate antiviral mediators. Federation of American Societies for Experimental Biology Conference. 19:A404.

TISSUE DISTRIBUTION OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS (PRRSV) IN FINISHER AGE BOARS AND GILTS AT VARIOUS TIMES POST INFECTION - (Proceedings)

Brockmeier, S., Lager, K.M. 2004. Tissue distribution of porcine reproductive and respiratory syndrome virus (prrsv) in finisher age boars and gilts at various times post infection. Pig Veterinary Society International Congress Proceedings. p. 51.

IMMUNE RESPONSE TO A DNA VACCINE DERIVED FROM THE PASTEURELLA MULTOCIDA TOXIN GENE - (Proceedings)

Register, K.B., Sacco, R.E., Brockmeier, S. 2004. Immune response to a dna vaccine derived from the pasteurella multocida toxin gene. Pig Veterinary Society International Congress Proceedings. p. 200.

PRIOR INFECTION WITH BORDETELLA BRONCHISEPTICA INCREASES COLONIZATION WITH HAEMOPHILUS PARASUIS IN SWINE - (Peer Reviewed Journal)

Brockmeier, S. 2004. Prior infection with bordetella bronchiseptica increases colonization with haemophilus parasuis in swine. Veterinary Microbiology. Vol. 99, p. 75-78.

A BORDETELLA BRONCHISEPTICA DNT MUTANT PREDISPOSES PIGS TO INFECTION WITH TOXIGENIC PASTEURELLA MULTOCIDA (POSTER PRESENTATION FOR THE 2003 ASM MEETING) - (Abstract Only)

BROCKMEIER, S.L., REGISTER, K.B. A BORDETELLA BRONCHISEPTICA DNT MUTANT PREDISPOSES PIGS TO INFECTION WITH TOXIGENIC PASTEURELLA MULTOCIDA. 103rd GENERAL MEETING OF THE AMERICAN SOCIETY FOR MICROBIOLOGY. 2003. Abstract p. 675, #Z-001.

MOLECULAR AND ANTIGENIC CHARACTERIZATION OF BORDETELLA BRONCHISEPTICA ISOLATED FROM A WILD SOUTHERN SEA OTTER (ENHYDRA LUTRIS NEREIS) WITH SUPPURATIVE BRONCHOPNEUMONIA - (Peer Reviewed Journal)

STAVELEY, C., REGISTER, K.B., MILLER, M., BROCKMEIER, S., JANG, S. MOLECULAR AND ANTIGENIC CHARACTERIZATION OF BORDETELLA BRONCHISEPTICA ISOLATED FROM A WILD SOUTHERN SEA OTTER (ENHYDRA LUTRIS NEREIS) WITH SUPPURATIVE BRONCHOPNEUMONIA. JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION. 2003. v. 15. p. 570-574.

A REVIEW OF AREA SPREAD AND SUMMARY OF RECENT STUDIES - (Proceedings)

LAGER, K.M., BROCKMEIER, S. A REVIEW OF AREA SPREAD AND SUMMARY OF RECENT STUDIES. PROCEEDINGS OF ALLEN D LEMAN SWINE CONFERENCE. 2002. p. 68-70.

EXPERIEMNTAL AIRBORNE TRANSMISSION OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS AND BORDETELLA BRONCHISEPTICA - (Peer Reviewed Journal)

BROCKMEIER, S.L. LAGER, K.M. EXPERIEMNTAL AIRBORNE TRANSMISSION OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS AND BORDETELLA BRONCHISEPTICA. VETERINARY MICROBIOLOGY. 2002. v. 89. p. 267-275.

EVALUATION OF IMMUNE RESPONSE INDUCED BY ATTENUATED AND WILD-TYPE PRRS VIRUS - (Proceedings) - (03-Jun-02)

INTERACTIONS AMONG PORCINE REPRODUCTIVE AND RESPIRATORY SYSTEM VIRUS (PRRSV), BRODETELLA BRONCHISEPTICA AND HAEMOPHILUS PARASUIS IN SWINE RESPIRATORY DISEASE - (Proceedings) - (01-Mar-02)

PORCINE RESPIRATORY DISEASE COMPLEX (BOOK CHAPTER FOR POLYMICROBIAL DISEASES) - (Book / Chapter) - (10-Dec-01)

COMPARISON OF CELLULAR IMMUNE RESPONSE INDUCED BY ATTENUATED AND WILD-TYPE PRRS VIRUS - (Abstract Only) - (11-Nov-01)

COMPARISON OF CELLULAR IMMUNE RESPONSE INDUCED BY ATTENUATED AND WILD-TYPE PRRS VIRUS - (Abstract Only) - (12-Oct-01)

ROLE OF THE DERMONECROTIC TOXIN OF BORDETELLA BRONCHISEPTICA IN THE PATHOGENESIS OF RESPIRATORY DISEASE OF SWINE - (Peer Reviewed Journal) - (27-Sep-01)

PRIOR INFECTION WITH BORDETELLA BRONCHISEPTICA INCREASES COLONIZATION WITH HAEMOPHILUS PARASUIS IN SWINE (ORAL PRESENTATION FOR THE 82ND CONFERENCE OF RESEARCH WORKERS IN ANIMAL DISEASE) - (Abstract Only) - (21-Sep-01)

BORDETELLA AND PASTEURELLA: THEIR ROLE IN PRDC AND RE-EMERGENCE OF ATROPHIC RHINITIS (PROCEEDINGS OF THE IOWA VETERINARY MEDICAL ASSOC., SEPT. 2001). - (Proceedings) - (31-Aug-01)

REDUCED VIRULENCE OF A BORDETELLA BRONCHISEPTICA SIDEROPHORE MUTANT IN NEONATAL SWINE - (Peer Reviewed Journal) - (04-Jan-01)

EVALUATION OF THE VIRULENCE OF A DERMONECROTIC TOXIN MUTANT OF BORDETELLA BRONCHISEPTICA IN SWINE (FOR THE INT. PIG VET. SOC. CONGR. IN AUSTRALIA, SEPT. 17-20, 2000) - (Proceedings) - (07-Jun-00)

INTERACTIONS AMONG PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS (PRRSV), BORDETELLA BRONCHISEPTICA AND PASTEURELLA MULTOCIDA IN SWINE RESPIRATORY DISEASE (FOR INT. PIG. VET. SOC. CONGR., IN AUSTRALIA, 9/2000) - (Proceedings) - (06-Jun-00)

EFFECTS OF INTRANSAL INOCULATION WITH BORDETELLA BRONCHISEPTICA, PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS, OR A COMBINATION OF BOTH ORGANISMS ON SUBSEQUENT INFECTION WITH PASTEURELLA MULTOCIDA IN PIGS - (Peer Reviewed Journal) - (23-May-00)

EFFECT OF TEMPERATURE MODULATION AND BVG MUTATION OF BORDETELLA BRONCHISEPTICA ON ADHESION, INTRACELLULAR SURVIVAL AND CYTOTOXICITY FOR SWINE ALVEOLAR MACROPHAGES - (Peer Reviewed Journal) - (16-Nov-99)

MIXED INFECTIONS WITH PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS BORDETELLA BRONCHISEPTICA AND PASTEURELLA MULTOCIDA IN SWINE - (Abstract Only) - (01-Oct-99)

ANALYSIS OF A BORDETELLA BRONCHISEPTICA DERMONECROTIC TOXIN MUTANT IN SWINE - (Abstract Only) - (01-Oct-99)

EFFECTS OF INTRANASAL INOCULATION OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS, BORDETELLA BRONCHISEPTICA, OR A COMBINATION OF BOTH ORGANISMS IN PIGS - (Peer Reviewed Journal) - (21-Sep-99)

EARLY COLONIZATION OF THE RAT UPPER RESPIRATORY TRACT BY TEMPERATURE MODULATED BORDETELLA BRONCHISEPTICA - (Peer Reviewed Journal) - (15-Mar-99)

CO-INFECTION WITH PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS AND BORDETELLA BRONCHISEPTICA IN WEANED PIGS (AMERICAN ASSOC. OF SWINE PRACTITIONERS CONF., FEB. 27 - MAR. 2, 1999) - (Proceedings) - (25-Feb-99)

CO-INFECTION WITH PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS AND BORDETELLA BRONCHISEPTICA IN PIGS (POSTER PRESENTATION FOR THE 99TH ASM GENERAL MEETING, MAY 30 - JUNE 3, 1999) - (Abstract Only) - (22-Feb-99)

REDUCED VIRULENCE OF A BORDETELLA BRONCHISEPTICA SIDEROPHORE MUTANT IN NEONATAL SWINE (POSTER PRESENTATION FOR THE 99TH ASM MEETING, MAY 30- JUNE 3, 1999) - (Abstract Only) - (22-Feb-99)

EVALUATION OF PROTECTIVE IMMUNITY IN GILTS INOCULATED WITH THE NADC-8 ISOLATE OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS (PRRSV) AND CHALLENGE-EXPOSED TO AN ANTIGENICALLY DISTINCT PRRSV ISOLATE - (Peer Reviewed Journal) - (09-Nov-98)

BORDETELLA BRONCHISEPTICA GROWN AT 23C ADHERES TO CELLS IN GREATER NUMBERS BUT DOES NOT SURVIVE INTRACELLULARLY AS COMPARED TO B. BRONCHISEPTICA GROWN AT 37C. - (Abstract Only) - (28-Sep-98)

PSEUDORABIES VIRUS (AUJESZKY'S DISEASE VIRUSU) - FOR IICAB, AMES, IA, JUNE 4, 1998. - (Proceedings) - (04-Jun-98)

INTERACTION OF BORDETELLA BRONCHISEPTICA WITH PORCINE ALVEOLAR MACROPHAGES (POSTER PRESENT.) - (Abstract Only) - (15-Oct-97)

HOMOLOGOUS CHALLENGE OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUSIMMUNITY IN PREGNANT SWINE - (Peer Reviewed Journal) - (16-May-97)

DURATION OF HOMOLOGOUS PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS IMMUNITY IN PREGNANT SWINE - (Peer Reviewed Journal) - (16-May-97)

PSEUDORABIES VIRUS (AUJESZKY'S DISEASE VIRUS) - FOR IICAB, AMES, IA, JUNE 4, 1997. - (Proceedings) - (15-May-97)

HUMORAL AND CELL-MEDIATED IMMUNE RESPONSE TO VACCINIA VIRUS VECTORS EXPRESSING GLYCOPROTEINS GB OR GD OF PSEUDORABIES VIRUS - (Abstract Only) - (01-Apr-97)

SUCCESSFUL PSEUDORABIES VACCINATION IN MATERNALLY IMMUNE PIGLETS USING RECOMBINANT VACCINIA VIRUS VACCINES - (Peer Reviewed Journal) - (27-Nov-96)

HUMORAL AND CELL MEDIATED IMMUNE RESPONSE IN PIGS TO GLYCOPROTEINS GB, GC AND GD OF PSEUDORABIES VIRUS DELIVERED BY A VACCINIA VIRUS VECTOR - (Proceedings) - (10-Jul-96)

PATHOGENESIS OF FETAL PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS INFECTION DURING EARLY AND LATE GESTATION - (Proceedings) - (10-Jul-96)

ATTENUATION OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS BY SERIAL PASSAGE IN CELL CULTURE - (Proceedings) - (10-Jul-96)

PSEUDORABIES VIRUS (AUJESZKY'S DISEASE VIRUS) - (Proceedings) - (28-Jun-96)

COMPARISON OF THE PROTECTIVE RESPONSE INDUCED BY NYVAC VACCINIA RECOMBINANTS EXPRESSING EITHER GP50 OR GII AND GP50 OF PSEUDORABIES VIRUS - (Peer Reviewed Journal) - (15-May-96)

COMPARISON AMONG STRAINS OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS AS TO THEIR ABILITY TO CAUSE REPRODUCTIVE FAILURE - (Peer Reviewed Journal) - (21-Mar-96)

VACCINATION FOR PSEUDORABIES IN THE PRESENCE OF MATERNAL IMMUNITY USING VACCINIA VIRUS RECOMBINANTS - (Abstract Only) - (14-Nov-95)

THE EFFECT OF VARIOUS STRAINS OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS ON REPRODUCTIVE EFFICIENCY OF GILTS INFECTED LATE IN GESTATION - (Proceedings) - (10-Nov-95)

TRANSMISSION RISKS WITH VIRUSES - (Proceedings) - (10-Nov-95)

PATHOGENESIS OF PRRS REPRODUCTIVE FAILURE - (Proceedings) - (10-Nov-95)

ISOLATION OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS FROM SELECTED TISSUES OF ADULT PIGS AT VARIOUS TIMES AFTER EXPERIMENTAL EXPOSURE - (Proceedings) - (31-Oct-95)

THE ROLE OF BIOTECHNOLOGICALLY ENGINEERED VACCINES AND DIAGNOSTICS IN PSEUDORABIES (AUJESZKY'S DISEASE) ERADICATION STRATEGIES - (Review Article) - (08-Aug-95)

THE EFFECT OF VARIOUS STRAINS OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS ON REPRODUCTIVE EFFICIENCY OF GILTS INFECTED LATE IN GESTATION - (Proceedings) - (07-Jun-95)

CHALLENGE OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS IMMUNITY IN PREGNANT SWINE - (Proceedings) - (18-May-95)

THE USE OF BIOTECHNOLOGICALLY ENGINEERED VACCINES AND DIAGNOSTICS IN ADV ERADICATION STRATEGIES - (Proceedings) - (03-May-95)

LIMITED CROSS-PROTECTION BETWEEN TWO STRAINS OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS IN PREGNANT SWINE - (Proceedings) - (01-May-95)