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United States Department of Agriculture

Agricultural Research Service

Mitchell Wise

Research Chemist


Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Association mapping of grain hardness, polyphenol oxidase, total phenolics, amylose content, and ß-glucan in US barley breeding germplasm - (Peer Reviewed Journal)
Mohammadi, M., Endelman, J.B., Nair, S., Chao, S., Jones, S.S., Muehlbauer, G.J., Ullrich, S.E., Baik, B.-K., Wise, M.L., Smith, K.P. 2014. Association mapping of grain hardness, polyphenol oxidase, total phenolics, amylose content, and ß-glucan in US barley breeding germplasm. Molecular Breeding. DOI 10.1007/s11032-014-0112-5
In vitro total antioxidant capacity and anti-flammatory activity of three common avenanthramides - (Peer Reviewed Journal)
Yang, J., Ou, B., Wise, M.L., Chu, Y. 2014. In vitro total antioxidant capacity and anti-flammatory activity of three common avenanthramides. Food Chemistry. 160:338-345.
Genetic analyses of anthocyanin concentrations and intensity of red bulb color among segregating haploid progenies of onion Reprint Icon - (Peer Reviewed Journal)
Duangjit, J., Welsh, K., Wise, M.L., Bohanec, B., Havey, M.J. 2014. Genetic analyses of anthocyanin concentrations and intensity of red bulb color among segregating haploid progenies of onion. Molecular Breeding. 34(1):75-85.
Chemo-enzymatic synthesis of physiologically modified avenanthramides - (Abstract Only) - (12-Apr-13)
In vitro antioxidant capacity and anti-inflammatory activity of seven common oats - (Peer Reviewed Journal)
Chu, Y., Wise, M.L., Gulvady, A.A., Chang, T., Kendra, D.F., Van Klinken, J., Shi, Y., O'Shea, M. 2013. In vitro antioxidant capacity and anti-inflammatory activity of seven common oats. Food Chemistry. 139:426-31.
Phytochemicals attenuating aberrant activation of ß-catenin in cancer cells - (Peer Reviewed Journal)
Wang, D., Wise, M.L., Li, F., Dey, M. 2012. Phytochemicals attenuating aberrant activation of ß-catenin in cancer cells. PLoS One. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0050508.
Avenanthramides: chemistry and biosynthesis - (Book / Chapter)
Wise, M.L. 2014. Avenanthramides: chemistry and biosynthesis. In: Chu, Y-F, editor. Oats, Nutrition and Technology. Oxford, UK: Wiley Blackwell. p.195-222.
Histological analysis and 3D reconstruction of winter cereal crowns recovering from freezing: a unique response in oat (Avena sativa L.) - (Peer Reviewed Journal)
Livingston, D.P., Henson, C.A., Wise, M.L., Tuong, T.D., Tallury, S., Duke, S. 2012. Histological analysis and 3D reconstruction of winter cereal crowns recovering from freezing: a unique response in oat (Avena sativa L.). PLoS One. 8(1): e53468.
A developmental profile of tocol accumulation in oat seeds Reprint Icon - (Peer Reviewed Journal)
Gutierrez-Gonzalez, J.J., Wise, M.L., Garvin, D.F. 2012. A developmental profile of tocol accumulation in oat seeds. Journal of Cereal Science. 57(1):79-83.
Avenanthramide biosynthesis in oat cultivars treated with systemic acquired resistance elicitors - (Peer Reviewed Journal)
Yi, R., Wise, M.L. 2013. Avenanthramide biosynthesis in oat cultivars treated with systemic acquired resistance elicitors. Cereal Research Communications. 41(2):255–265.
Plant defense activators: applications and prospects in cereal crops - (Review Article)
Wise, M.L. 2014. Plant defense activators: Applications and prospects in cereal crops. In: D.R. Gang, editor. Recent Advances in Phytochemistry, Vol 43, “50 Years of Phytochemical Research”. Springer International. p. 55-70.
A gene expression atlas of developing oat seeds for enhancing nutritional composition - (Abstract Only)
Gutierrez-Gonzalez, J.J., Wise, M.L., Garvin, D.F. 2012. A gene expression atlas of developing oat seeds for enhancing nutritional composition [abstract]. Plant and Animal Genome XX Conference, January 14-18, 2012, San Diego, California. Available: https://pag.confex.com/pag/xx/webprogram/Paper3489.html.
Plant defense activators as elicitors of oat avenanthramide biosynthesis - (Abstract Only)
Wise, M.L. 2011. Plant defense activators as elicitors of oat avenanthramide biosynthesis [abstract]. North American Phytochemical Society Annual Meeting, Kamuela, Hawaii, December 10-15, 2011. p.95.
Effect of chemical systemic acquired resistance elicitors on avenanthramide biosynthesis in oat (Avena sativa) Reprint Icon - (Peer Reviewed Journal)
Wise, M.L. 2011. Effect of chemical systemic acquired resistance elicitors on avenanthramide biosynthesis in oat (Avena sativa). Journal of Agriculture and Food Chemistry. 59:7028-7038.
Avenanthramides are bioavailable and accumulate in hepatic, cardiac, and skeletal muscle tissue following oral gavage in rats Reprint Icon - (Peer Reviewed Journal)
Koenig, R.T., Dickman, J.R., Wise, M.L., Ji, L. 2011. Avenanthramides are bioavailable and accumulate in hepatic, cardiac, and skeletal muscle tissue following oral gavage in rats. Journal of Agricultural and Food Chemistry. 59(12):6438-6443.
In vitro antioxidant activity and inhibitory effect, on oleic acid-induced hepatic steatosis, of fractions and subfractions from oat (Avena sativa L.) ethanol extract Reprint Icon - (Peer Reviewed Journal)
Cai, S., Huang, C., Ji, B., Wise, M.L., Zhang, D., Yang, P. 2011. In vitro antioxidant activity and inhibitory effect, on oleic acid-induced hepatic steatosis, of fractions and subfractions from oat (Avena sativa L.) ethanol extract. Journal of Food Science. 124(3):900-905.
Avenanthramides inhibit proliferation of human colon cancer cell lines in vitro Reprint Icon - (Peer Reviewed Journal)
Guo, W., Nie, L., Wu, D., Wise, M.L., Collins, F., Meydani, S., Meydani, M. 2010. Avenanthramides inhibit proliferation of human colon cancer cell lines in vitro. Nutrition and Cancer. 62(8):1007-1016.
The Effect of Chemical Systemic Acquired Resistance Elicitors on Oat Avenanthramide Biosynthesis - (Abstract Only)
Wise, M.L. 2010. The Effect of Chemical Systemic Acquired Resistance Elicitors on Oat Avenanthramide Biosynthesis [abstract]. In: American Oat Workers Conference Proceedings, April 17-21, 2010, Baton Rouge, Louisiana. p. 4.
Oat Avenanthramides: A Novel Antioxidant - (Book / Chapter)
Ji, L., Koenig, R., Wise, M.L. 2008. Oat Avenanthramides: A Novel Antioxidant. In: Mine, Y., Miyashita, K., Shahidi, F., editors. Nutrigenomics and proteomics in Health and Disease. Ames, IA: Wiley-Blackwell. p. 239-249.
Large Scale Survey of Tocol Content in Barley Germplasm - (Abstract Only)
Wise, M.L. 2009. Large Scale Survey of Tocol Content in Barley Germplasm. American Society of Plant Biologists Annual Meeting, July 18-22, 2009, Honolulu, Hawaii. Poster No. P60028.
The Green Oat Story: Possible Mechanisms of Green Color Formation in Oat Products During Cooking Color Changes in Cooked Oat Products - (Peer Reviewed Journal)
Doehlert, D.C., Simsek, S., Wise, M.L. 2009. The Green Oat Story: Possible Mechanisms of Green Color Formation in Oat Products During Cooking Color Changes in Cooked Oat Products. Journal of Food Science. 74(6):S226-S231
Barley and Oat beta-Glucan content measured by Calcofluor fluorescence in a microplate assay - (Peer Reviewed Journal)
Schmitt, M., Wise, M.L. 2009. Barley and Oat beta-Glucan Content Measured by Calcofluor Fluorescence in a Microplate Assay. Cereal Chemistry. 86(2)187-190.
Biosynthesis of avenanthramides in suspension cultures of oat (Avena sativa) - (Peer Reviewed Journal)
Wise, M.L., Sreenath, H.K., Skadsen, R.W., Kaeppler, H.F. 2009. Biosynthesis of Avenanthramides in Suspension Cultures of Oat (Avena sativa). Plant Cell Tissue And Organ Culture. 97:81-90.
QTLs Affecting a-Tocotrienol, a-Tocopherol, and Total Tocopherol Concentrations Detected in the Ogle/TAM O-301 Oat Mapping Population. Reprint Icon - (Peer Reviewed Journal)
Jackson, E.W., Wise, M., Bonman, J.M.,Obert, D.E., Hu, G. and Peterson. D.M.. 2008. QTLs Affecting -tocotrienol, -tocopherol, and total tocopherol concentrations detected in the Ogle/TAM O-301 oat mapping population. Crop Science 48:2141-2152.
Tocol Content of Barley CAP germplasm, Preliminary Results - (Abstract Only)
Wise, M.L. 2008. Tocol Content of Barley CAP germplasm, Preliminary Results. In: North American Barley Research Workshop Proceedings, October 26-29, 2008, Madison, Wisconsin. p. 38.
Barley and oat beta-glucan content measured by calcofluor fluorescence in a microplate assay - (Abstract Only)
Schmitt, M., Wise, M.L. 2008. Barley and Oat Beta-Glucan Content Measured by Calcofluor Fluorescence in a Microplate Assay. North American Barley Research Workshop Proceedings, October 26-29, 2008, Madison, WI.
Factors Effecting Phytonutrient Biosynthesis in Oat - (Abstract Only)
Wise, M.L., Jackson, E.W., Doehlert, D.C. 2008. Factors Effecting Phytonutrient Biosynthesis in Oat [abstract]. In: International Oat Conference, June 28 - July 2, 2008, Minneapolis, Minnesota. p. 5.
Association of Avenanthramide Concentration in Oat (Avena sativa) Grain with Crown Rust Incidence and Genetic Resistence - (Peer Reviewed Journal)
Wise, M.L., Doehlert, D.C., Mcmullen, M.S. 2008. Association of Avenanthramide Concentration in Oat (Avena sativa) Grain with Crown Rust Incidence and Genetic Resistence. Cereal Chemistry. 85(5)639-641.
Avenanthramides, polyphenols from oats, inhibit IL-1 beta-induced NF-kappaB activation in endothelial cells - (Peer Reviewed Journal)
Guo, W., Wise, M.L., Collins, F.W., Meydani, M. 2008. Avenanthramides, polyphenols from oats, inhibit IL-1 beta-induced NF-kappaB activation in endothelial cells. Free Radicals in Biology and Medicine. 44:415-429.
How can varieties and rain-fed production environments affect malting quality in spring barley? - (Abstract Only)
Ullrich, S.E., Jitkov, V.A., Budde, A.D., Schmitt, M., Wise, M.L. 2007. How can varieties and rain-fed production environments affect malting quality in spring barley?. American Society of Brewing Chemists Newsletter. 67(2)P50.
Avenanthramide bioavailability and tissue distribution in rats - (Abstract Only)
Koenig, R., Dickman, J., Wise, M.L., Ji, L. 2007. Avenanthramide bioavailability and tissue distribution in rats [abstract]. Journal of FASEB. 21:701.1.
Mechanism by Which Avenanthramide-C, a Polyphenol of Oats, Blocks Cell Cycle Progression in Vascular Smooth Muscle Cells - (Abstract Only)
Nie, L., Wise, M., Meydani, M. 2006. Mechanism by Which Avenanthramide-C, a Polyphenol of Oats, Blocks Cell Cycle Progression in Vascular Smooth Muscle Cells. AGE. 28(1):54-55.
Methyl Ester of Avenanthramide-C Inhibits Tnfa and Il-1b-Induced Nf-Kb Activation in Endothelial Cells - (Abstract Only)
Guo, W., Wise, M.L., Meydani, M. 2006. Methyl ester of avenanthramide-c inhibits tnfa- and il-1b-induced nf-kb activation in endothelial cells. AGE. 28(1):35-36.
Avenanthramides in Oat (Avena Sativa), a Value Added Phytonutrient - (Proceedings)
Wise, M.L. 2006. Avenanthramides in oat (Avena sativa), a value added phytonutrient. In: American Oat Workers Program Book. p. 38.
Mechanism by Which Avenanthramide-C, a Polyphenol of Oats, Blocks Cell Cycle Progression in Vascular Smooth Muscle Cells - (Peer Reviewed Journal)
Nie, L., Wise, M.L., Peterson, D.B., Meydani, M. 2006. Mechanism by which avenanthramide-c, a polyphenol of oats, blocks cell cycle progression in vascular smooth muscle cells. Free Radicals in Biology and Medicine. 41(5):702-8.
Methyl ester of avenathramide-C inhibits tumor necrosis factor-alpha (TNF-alpha) and interlenkin-Ibeta(IL-beta)-induced NF-kappaB activation in endothelial cells - (Abstract Only)
Guo, W., Wise, M.L., Peterson, D., Meydani. 2006. Methyl ester of avenanthramide-c inhibits tnfalpha- and il-1beta-induced nf-kappab activation in endothelial cells. Federation of American Societies for Experimental Biology Conference. 20:A1000.
Biosynthesis of Avenanthramides in Chitin Elicited Oat (Avena Sativa) Suspension Cultures Reprint Icon - (Abstract Only)
Wise, M.L. 2006. Biosynthesis of avenanthramides in chitin elicited oat (Avena sativa) suspension cultures [abstract]. In Vitro Biology Meeting. p. 34. Paper No. P-2002.
Avenanthramide, a Polyphenol from Oats, Inhibits Vascular Smooth Muscle Cell Proliferation and Enhances Nitric Oxide Production - (Peer Reviewed Journal)
Nie, L., Wise, M.L., Peterson, D.W., Meydani, M. 2006. Avenanthramide, a polyphenol from oats, inhibits vascular smooth muscle cell proliferation and enhances nitric oxide production. Atherosclerosis. 186(2):260-6.
Mechanism by Which Avenanthramide-C, a Polyphenol of Oats, Blocks Cell Cycle Progression in Vascular Smooth Muscle Cells - (Abstract Only)
Nie, L., Wise, M., Peterson, D., Meydani, M. 2005. Mechanism by which avenanthramide-c, a polyphenol of oats, blocks cell cycle progression in vascular smooth muscle cells. Federation of American Societies for Experimental Biology Conference. 20:A1014.
Modulation of Vascular Smooth Muscle Cell Proliferation and Nitric Oxide Production by Avenanthramides, Polyphenols from Oats - (Abstract Only)
Nie, L., Wise, M.L., Peterson, D., Meydani, M. 2005. Modulation of vascular smooth muscle cell proliferation and nitric oxide production by avenanthramides, polyphenols from oats. Journal of Federation of American Societies for Experimental Biology. 19:A1476.
Monoterpene Biosynthesis in Marine Algae - (Peer Reviewed Journal)
WISE, M.L. MONOTERPENE BIOSYNTHESIS IN MARINE ALGAE. PHYCOLOGIA JOURNAL. 2003. 42(4):370-377.
Syn Stereochemistry of Cyclic Ether Formation in 1,8-Cineole Biosynthesis Catalyzed by Recombinant Synthase from Salvia Officinalis - (Peer Reviewed Journal)
WISE, M.L., URBANSKY, M., HELMS, G.L., COATES, R.M., CROTEAU, R. SYN STEREOCHEMISTRY OF CYCLIC ETHER FORMATION IN 1,8-CINEOLE BIOSYNTHESIS CATALYZED BY RECOMBINANT SYNTHASE FROM SALVIA OFFICINALIS. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2002. 124(29):8546-7.
Last Modified: 11/15/2013
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