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United States Department of Agriculture

Agricultural Research Service

Related Topics

James L Klotz
Forage-animal Production Research
Animal Science

Phone: (859) 257-1647
Fax: (859) 257-3334

Room N-220
1100 S. LIMESTONE-AGRICULTURAL SCIENCE BUILDING N.
UNIVERSITY OF KENTUCKY CAMPUS
LEXINGTON , KY 40546

Projects
Synthesis of Ergovaline for Physiology Experiments
General Cooperative Agreement (A)
  Accession Number: 427512
Optimizing the Biology of the Animal-Plant Interface for Improved Sustainability of Forage-Based Animal Enterprises
Appropriated (D)
  Accession Number: 423805
Impacts of Fescue Toxicosis on Fetal Development and Postnatal Growth
Nonfunded Cooperative Agreement (N)
  Accession Number: 430399
Utilizing the University of Kentucky Animal Care and Use Committee
Nonfunded Cooperative Agreement (N)
  Accession Number: 430905

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Interaction between a tannin-containing legume and endophyte-infected tall fescue seed on lambs’ feeding behavior and physiology -
Villalba, J.J., Spackman, C., Goff, B.M., Klotz, J.L., Griggs, T., Macadam, J.W. 2015. Interaction between a tannin-containing legume and endophyte-infected tall fescue seed on lambs’ feeding behavior and physiology. Journal of Animal Science. doi: 10.2527/jas.2015-9790.
Interaction of isoflavones and endophyte-infected tall fescue seed extract on vasoactivity of bovine mesenteric vasculature -
Jia, Y., Harmon, D.L., Flythe, M.D., Klotz, J.L. 2015. Interaction of isoflavones and endophyte-infected tall fescue seed extract on vasoactivity of bovine mesenteric vasculature. Frontiers in Nutrition: Animal Nutrition and Metabolism. doi: 10.3389/fnut.2015.00032.
Physiologic effects of ergot alkaloids: What happens when excretion does not equal consumption? -
Klotz, J.L. 2015. Physiologic effects of ergot alkaloids: What happens when excretion does not equal consumption?. Journal of Animal Science. 93:5512-5521.
Activities and effects of ergot alkaloids on livestock physiology and production -
Klotz, J.L. 2015. Activities and effects of ergot alkaloids on livestock physiology and production. Toxins. 7:2801-2821; doi:10.3390/toxins7082801.
The difficulties in reviewing ergovaline -
Effect of grazing seedhead-suppressed tall fescue pasture on the vasoactivity of serotonin receptors -
Interaction between a tannin-containing legume and endophyte-infected tall fescue seed on lambs’ feeding behavior and physiology -
Recent investigations of ergot alkaloids incorporated into plant and/or animal systems -
Klotz, J.L., Smith, D.L. 2015. Recent investigations of ergot alkaloids incorporated into plant and/or animal systems. Frontiers in Chemistry: Chemical Biology. 3:23. doi:10.3389/fchem.2015.00023.
Hops (Humulus lupulus) ß-acid as an inhibitor of caprine rumen hyper-ammonia-producing bacteria in vitro -
Flythe, M.D., Aiken, G.E., Gellin, G.L., Klotz, J.L., Goff, B.M., Andries, K. 2015. Hops (Humulus lupulus) ß-acid as an inhibitor of caprine rumen hyper-ammonia-producing bacteria in vitro. Agriculture, Food and Analytical Bacteriology. 5:29-36.
Cases of ergotism in livestock and associated ergot alkaloid concentrations in feed -
Craig, A., Klotz, J.L., Duringer, J.M. 2015. Cases of ergotism in livestock and associated ergot alkaloid concentrations in feed. Frontiers in Chemistry: Chemical Biology. 3:8. doi:10.3389/fchem.2015.00008.
Tall fescue seed extraction and partial purification of ergot alkaloids -
Huihua, J., Fannin, N., Klotz, J.L., Bush, L.P. 2014. Tall fescue seed extraction and partial purification of ergot alkaloids. Frontiers in Chemistry: Chemical Biology. 2:110.
Physiologic effects of ergot alkaloids: What happens when excretion does not equal absorption? -
Klotz, J.L. 2015. Physiologic effects of ergot alkaloids: What happens when excretion does not equal absorption?. American Society of Animal Science Southern Section Meeting. Pg. 92.
Development of a methodology to measure the effect of ergot alkaloids on forestomach motility using real-time wireless telemetry -
Egert, A.M., Klotz, J.L., McLeod, K.R., Harmon, D.L. 2014. Development of a methodology to measure the effect of ergot alkaloids on forestomach motility using real-time wireless telemetry. Frontiers in Chemistry: Chemical Biology. 2:90.
Effect of intake on fasting heat production, respiratory quotient and plasma metabolites measured using the washed rumen technique -
Kim, D., McLeod, K.R., Koontz, A.F., Foote, A.P., Klotz, J.L., Harmon, D.L. 2015. Effect of intake on fasting heat production, respiratory quotient and plasma metabolites measured using the washed rumen technique. Animal. 9:58-66.
Effect of fescue toxicosis on whole body energy and nitrogen balance, in situ degradation and ruminal passage rates in Holstein steers -
Koontz, A.F., Kim, D., Mc Leod, K.R., Klotz, J.L., Harmon, D.L. 2014. Effect of fescue toxicosis on whole body energy and nitrogen balance, in situ degradation and ruminal passage rates in Holstein steers. Animal Production Science. 55:988-998. doi.org/10.1071/AN14037.
Isolating and using sections of bovine mesenteric artery and vein as a bioassay to test for vasoactivity in the small intestine -
Klotz, J.L., Barnes, A.J. 2014. Isolating and using sections of bovine mesenteric artery and vein as a bioassay to test for vasoactivity in the small intestine. Journal of Visualized Experiments. 92:e52020.
Effects of ergot alkaloid exposure on serotonin receptor mRNA in the smooth muscle of the bovine gastrointestinal tract -
Klotz, J.L., Kim, D., Foote, A.P., Harmon, D.L. 2014. Effects of ergot alkaloid exposure on serotonin receptor mRNA in the smooth muscle of the bovine gastrointestinal tract. Joint Meeting of the ADSA, AMSA, ASAS and PSA. 92(E.Suppl.2):890.
Effects of fescue toxicosis induced by endophyte-infected tall fescue seed on forestomach epithelial gene expression in Angus steers -
Kim, D., Klotz, J.L., Harmon, D.L. 2014. Effects of fescue toxicosis induced by endophyte-infected tall fescue seed on forestomach epithelial gene expression in Angus steers. Joint Meeting of the ADSA, AMSA, ASAS and PSA. 92(E.Suppl.2):898.
Analysis of rumen motility patterns using a wireless telemetry system to characterize bovine reticuloruminal contractions -
Egert, A.M., Mcleod, K.R., Klotz, J.L., Harmon, D.L. 2014. Analysis of rumen motility patterns using a wireless telemetry system to characterize bovine reticuloruminal contractions. Joint Meeting of the ADSA, AMSA, ASAS and PSA. 92(E.Suppl.2):804.
Effect of acute exposure to ergot alkaloids on short-chain fatty acid absorption and barrier function of isolated bovine ruminal epithelium -
Foote, A.P., Penner, G.P., Walpole, M.E., Klotz, J.L., Bush, L.P., Harmon, D.L. 2014. Effect of acute exposure to ergot alkaloids on short-chain fatty acid absorption and barrier function of isolated bovine ruminal epithelium. Joint Meeting of the ADSA, AMSA, ASAS and PSA. 92(E.Suppl.2):874.
Acute exposure to ergot alkaloids from endophyte-infected tall fescue does not alter absorptive or barrier function of the isolated ruminal epithelium -
Foote, A.P., Penner, G.P., Walpole, M.E., Klotz, J.L., Brown, K.R., Bush, L.P., Harmon, D.L. 2014. Acute exposure to ergot alkaloids from endophyte-infected tall fescue does not alter absorptive or barrier function of the isolated ruminal epithelium. Animal. 8(7):1106-1112.
Bovine lateral saphenous veins exposed to ergopeptine alkaloids do not relax -
Pesqueira, A., Harmon, D.L., Branco, A.F., Klotz, J.L. 2014. Bovine lateral saphenous veins exposed to ergopeptine alkaloids do not relax. Journal of Animal Science. 92:1213-1218.
Dietary exposure to ergot alkaloids decreases contractility of bovine mesenteric vasculature -
Egert, A.M., Kim, D., Schrick, F., Harmon, D.L., Klotz, J.L. 2014. Dietary exposure to ergot alkaloids decreases contractility of bovine mesenteric vasculature. Journal of Animal Science. 92:1768-1779.
Postgraze assessment of toxicosis symptoms for steers grazed on toxic and novel endophyte-infected tall fescue pasture -
Aiken, G.E., Klotz, J.L., Johnson, J.M., Strickland, J.R., Schrick, F.N. 2013. Postgraze assessment of toxicosis symptoms for steers grazed on toxic and novel endophyte-infected tall fescue pasture. Journal of Animal Science. 91:5878-5884.
Ergot alkaloids from endophyte-infected tall fescue decrease reticulo-ruminal epithelial blood flow and volatile fatty acid absorption from a washed reticulorumen -
Foote, A.P., Kristensen, N.B., Klotz, J.L., Kim, D., Koontz, A.F., Mcleod, K.R., Bush, L.P., Schrick, F.N., Harmon, D.L. 2013. Ergot alkaloids from endophyte-infected tall fescue decrease reticulo-ruminal epithelial blood flow and volatile fatty acid absorption from a washed reticulorumen. Journal of Animal Science. 91:5366-5378.
Antimicrobial activity of red clover (Trifolium pratense L.) extract on caprine hyper ammonia-producing bacteria -
Flythe, M.D., Harrison, B., Kagan, I., Klotz, J.L., Gellin, G.L., Goff, B.M., Aiken, G.E. 2013. Antimicrobial activity of red clover (Trifolium pratense L.) extract on caprine hyper ammonia-producing bacteria. Agriculture, Food and Analytical Bacteriology. 3:176-185.
Evaluation of a rapid determination of heat production and respiratory quotient in holstein steers using the washed rumen technique -
Kim, D., Mcleod, K.R., Klotz, J.L., Koontz, A.F., Foote, A.P., Harmon, D.L. 2013. Evaluation of a rapid determination of heat production and respiratory quotient in holstein steers using the washed rumen technique. Journal of Animal Science. 91:4267-4276.
Antagonism of lateral saphenous vein serotonin receptors from steers grazing endophyte-free, wild-type, or novel endophyte-infected tall fescue -
Klotz, J.L., Aiken, G.E., Johnson, J.M., Brown, K.R., Bush, L.P., Strickland, J.R. 2013. Antagonism of lateral saphenous vein serotonin receptors from steers grazing endophyte-free, wild-type, or novel endophyte-infected tall fescue. Journal of Animal Science. 91:4492-4500.
Alteration of fasting heat production during fescue toxicosis in Holstein steers -
Koontz, A.F., Kim, D., Foote, A.P., Bush, L.P., Klotz, J.L., Mcleod, K.R., Harmon, D.L. 2013. Alteration of fasting heat production during fescue toxicosis in Holstein steers. Journal of Animal Science. 91:3881-3888.
Bovine lateral saphenous veins exposed to ergopeptine alkaloids do not relax -
Klotz, J.L., Pesqueira, A., Branco, A.F., Harmon, D.L. 2013. Bovine lateral saphenous veins exposed to ergopeptine alkaloids do not relax. J. Anim. Sci. Vol. 91, E-Suppl. 2:92.
Effect of endophyte-infected tall fescue seed on ruminal metabolism and physiology in Angus steers -
Kim, D.H., Klotz, J.L., Harmon, D.L. 2013. Effect of endophyte-infected tall fescue seed on ruminal metabolism and physiology in Angus steers. J. Anim. Sci. Vo. 91, E-Suppl. 2:522-523.
Equine palmar artery, palmar vein and uterine artery express different populations of vasoactive biogenic amine receptors -
Hestad, D.A., Mcdowell, K.J., Klotz, J.L. 2013. Equine palmar artery, palmar vein and uterine artery express different populations of vasoactive biogenic amine receptors. J. Anim. Sci. Vol. 91, E-Suppl. 2:566.
Dietary exposure to ergot alkaloids decreases contractility of bovine mesenteric vasculature -
Egert, A.M., Kim, D., Harmon, D.L., Klotz, J.L. 2013. Dietary exposure to ergot alkaloids decreases contractility of bovine mesenteric vasculature. J. Anim. Sci. Vol. 91, E-Suppl. 2:214.
Effect of fescue toxicosis on ruminal kinetics, nitrogen and energy balance in Holstein steers -
Koontz, A.F., Foote, A.P., Kim, D.H., Klotz, J.L., Mcleod, K.R., Harmon, D.L. 2013. Effect of fescue toxicosis on ruminal kinetics, nitrogen and energy balance in Holstein steers. J. Anim. Sci. Vol. 91, E-Suppl. 2:92.
Application of washed rumen technique for rapid determination of fasting heat production in steers -
Kim, D.H., Mcleod, K.R., Klotz, J.L., Koontz, A.F., Foote, A.P., Harmon, D.L. 2013. Application of washed rumen technique for rapid determination of fasting heat production in steers. In: Energy and Protein Metabolism and Nutrition in Sustainable Animal Production. 134:235-236.
Effect of fescue toxicosis on nitrogen and energy balance in Holstein steers -
Koontz, A.F., Kim, D.H., Foote, A.P., Bush, L.P., Klotz, J.L., Mcleod, K.R., Harmon, D.L. 2013. Effect of fescue toxicosis on nitrogen and energy balance in Holstein steers. In: Energy and Protein Metabolism and Nutrition in Sustainable Animal Production. 134:67-68.
Ergot alkaloids produced by endophyte-infected tall fescue decrease rumen epithelial blood flow of cattle -
Foote, A.P., Kristensen, N.B., Klotz, J.L., Mcleod, K.R., Bush, L.P., Harmon, D.L. 2013. Ergot alkaloids produced by endophyte-infected tall fescue decrease rumen epithelial blood flow of cattle. American Forage and Grassland Council Conference Proceedings. Pg. 8.
Vascular activity increases with time off of tall fescue -
Klotz, J.L., Aiken, G.E., Foote, A.P., Bussard, J.R., Brown, K.R., Goff, B.M., Harmon, D.L., Strickland, J.R. 2014. Vascular activity increases with time off of tall fescue. Kentucky Beef Report. pgs. 19-22.
Ergot alkaloids reduce rumen epithelial blood flow and volatile fatty acid absorption -
Foote, A.P., Kristensen, N.B., Klotz, J.L., Kim, D., Koontz, A.F., Mcleod, K.R., Bush, L.P., Harmon, D.L. 2014. Ergot alkaloids reduce rumen epithelial blood flow and volatile fatty acid absorption. Kentucky Beef Report. pgs. 16-19.
Evaluation of a rapid determination of heat production and respiratory quotient in Holstein steers using the washing rumen technique -
Kim, D., Mcleod, K.R., Klotz, J.L., Koontz, A.F., Foote, A.P., Harmon, D.L. 2014. Evaluation of a rapid determination of heat production and respiratory quotient in Holstein steers using the washing rumen technique. Kentucky Beef Report. pgs. 26-28.
Alteration of basal metabolic rate in Holstein steers during fescue toxicosis -
Koontz, A.F., Foote, A.P., Kim, D., Bush, L.P., Klotz, J.L., Mcleod, K.R., Harmon, D.L. 2014. Alteration of basal metabolic rate in Holstein steers during fescue toxicosis. Kentucky Beef Report. pgs. 7-9.
Constriction of bovine vasculature caused by endophyte-infected tall fescue seed extract is similar to pure ergovaline -
Foote, A.P., Harmon, D.L., Brown, K.R., Strickland, J.R., Mcleod, K.R., Bush, L.P., Klotz, J.L. 2014. Constriction of bovine vasculature caused by endophyte-infected tall fescue seed extract is similar to pure ergovaline. Kentucky Beef Report. pgs. 13-15.
Validation of a housekeeping gene for use in bovine vascular gene expression studies -
Klotz, J.L., Brown, K.R., Matthews, J.C., Boling, J.A., Strickland, J.R. 2012. Validation of a housekeeping gene for use in bovine vascular gene expression studies. J. Anim. Sci. Vol 90, Suppl 3:pg 35.
Lateral saphenous vein responses to serotonergic and a-adrenergic receptor agonists increase with time off endophyte-infected tall fescue -
Klotz, J.L., Bussard, J.R., Aiken, G.E., Foote, A.P., Harmon, D.L., Brown, K.R., Goff, B.M., Strickland, J.R. 2012. Lateral saphenous vein responses to serotonergic and a-adrenergic receptor agonists increase with time off endophyte-infected tall fescue. J. Anim. Sci. Vol. 90, Suppl. 3:34.
Ergovaline disappearance from a ruminally incubated buffer -
Foote, A.P., Kristensen, N.B., Klotz, J.L., Brown, K.R., Strickland, J.R., Kim, D.H., Koontz, A.E., Mcleod, K.R., Bush, L.P., Harmon, D.L. 2012. Ergovaline disappearance from a ruminally incubated buffer. J. Anim. Sci. Vol. 90, Suppl. 3:94.
Ergot alkaloids decrease rumen epithelial blood flow -
Foote, A.P., Kristensen, N.B., Klotz, J.L., Kim, D.H., Koontz, A.F., Mcleod, K.R., Bush, L.P., Harmon, D.L. 2012. Ergot alkaloids decrease rumen epithelial blood flow. J. Anim. Sci. Vol. 90, Suppl. 3:431-432.
Evaluation of a rapid determination of heat production and respiratory quotient in Holstein steers using the washed rumen technique -
Kim, D.H., Mcleod, K.R., Klotz, J.L., Koontz, A.F., Foote, A.P., Harmon, D.L. 2012. Evaluation of a rapid determination of heat production and respiratory quotient in Holstein steers using the washed rumen technique. J. Anim. Sci. Vol. 90, Suppl. 3:99.
Alteration of fasting heat production during fescue toxicosis in Holstein steers -
Koontz, A.F., Foote, A.P., Kim, D.H., Bush, L.P., Klotz, J.L., Mcleod, K.R., Harmon, D.L. 2012. Alteration of fasting heat production during fescue toxicosis in Holstein steers. J. Anim. Sci. Vol. 90, Suppl. 3:622-623.
Changes in bovine vascular contraction and constriction relative to time off endophyte-infected tall fescue -
Bussard, J.R., Aiken, G.E., Strickland, J.R., Brown, K.R., Goff, B.M., Foote, A.P., Klotz, J.L. 2012. Changes in bovine vascular contraction and constriction relative to time off endophyte-infected tall fescue. J. Anim. Sci. Vol. 90, Suppl. 3:34.
Steer and pasture responses for a novel endophyte tall fescue developed for the upper transition zone -
Johnson, J.M., Aiken, G.E., Phillips, T.D., Barrett, M., Klotz, J.L., Schrick, F.N. 2012. Steer and pasture responses for a novel endophyte tall fescue developed for the upper transition zone. Journal of Animal Science. 90:2402-2409.
Constriction of bovine vasculature by endophyte-infected tall fescue seed extract is similar to pure ergovaline -
Foote, A.P., Harmon, D.L., Brown, K.R., Strickland, J.R., Mcleod, K.R., Bush, L.P., Klotz, J.L. 2012. Constriction of bovine vasculature by endophyte-infected tall fescue seed extract is similar to pure ergovaline. Journal of Animal Science. 90:1603-1609.
Evaluation of a ruminally dosed tall fescue seed extract as a model for fescue toxicosis in steers -
Koontz, A.F., Bush, L.P., Klotz, J.L., Mcleod, K.R., Schrick, F.N., Harmon, D.L. 2012. Evaluation of a ruminally dosed tall fescue seed extract as a model for fescue toxicosis in steers. Journal of Animal Science. 90:914-921.
Alterations in serotonin receptor-induced contractility of bovine lateral saphenous vein in cattle grazing endophyte-infected tall fescue -
Klotz, J.L., Brown, K.R., Xue, Y., Matthews, J.C., Boling, J.A., Burris, W.R., Bush, L.P., Strickland, J.R. 2012. Alterations in serotonin receptor-induced contractility of bovine lateral saphenous vein in cattle grazing endophyte-infected tall fescue. Journal of Animal Science. 90:682-693.
Protein degradation of smooth bromegrass switchgrass and big bluestem in grazing cattle -
Kirch, B.H., Moser, L.E., Waller, S.S., Klopfenstein, T.J., Klotz, J.L. 2011. Protein degradation of smooth bromegrass switchgrass and big bluestem in grazing cattle. The Professional Animal Scientist. 27:422-427.
Disrupted hair follicle activity in cattle grazing endophyte-infected tall fescue in the summer insulates core body temperatures -
Aiken, G.E., Klotz, J.L., Looper, M.L., Tabler, S.F., Schrick, F.N. 2011. Disrupted hair follicle activity in cattle grazing endophyte-infected tall fescue in the summer insulates core body temperatures. Professional Animal Scientist. 27:336-343.
Effect of ergot alkaloids on contractility of bovine right ruminal artery and vein -
Foote, A.P., Harmon, D.L., Strickland, J.R., Bush, L.P., Klotz, J.L. 2011. Effect of ergot alkaloids on contractility of bovine right ruminal artery and vein. Journal of Animal Science. 89:2944-2949.
Contractile response of bovine lateral saphenous vein to ergovaline serotonin2A a2A- and a2C-adrenergic receptor agonists relative to time off endophyte-infected tall fescue -
Klotz, J.L., Aiken, G.E., Foote, A.P., Bush, L.P., Brown, K.R., Goff, B.M., Strickland, J.R. 2011. Contractile response of bovine lateral saphenous vein to ergovaline serotonin2A a2A- and a2C-adrenergic receptor agonists relative to time off endophyte-infected tall fescue. Joint Meeting of the ADSA, AMSA, ASAS and PSA. 89(E-Suppl. 1):50.
Endophyte-infected tall fescue seed extract induces constriction of bovine vasculature -
Foote, A.P., Harmon, D.L., Brown, K.R., Strickland, J.R., Mcleod, K.R., Bush, L.P., Klotz, J.L. 2011. Endophyte-infected tall fescue seed extract induces constriction of bovine vasculature. Joint Meeting of the ADSA, AMSA, ASAS and PSA. 89(E-Suppl. 1):49-50.
Ergot alkaloids: toxicokinetics and vascular effects -
Strickland, J.R., Brown, K.R., Aiken, G.E., Klotz, J.L., Flythe, M.D. 2012. Ergot alkaloids: toxicokinetics and vascular effects. International Symposium on Fungal Endophytes of Grasses. pgs 14-19.
A vascular contractility bioassay using bovine right ruminal artery and vein -
Klotz, J.L., Bush, L.P., Strickland, J.R. 2011. A vascular contractility bioassay using bovine right ruminal artery and vein. Journal of Animal Science. 89:1944-1951.
Tall Fescue Alkaloids Bind Serotonin Receptors in Cattle -
Klotz, J.L., Strickland, J.R., Bush, L.P., Brown, K.R., Aiken, G.E. 2010. Tall Fescue Alkaloids Bind Serotonin Receptors in Cattle. Kentucky Beef Report. pgs 37-43.
Effect of Ergot Alkaloids on Bovine Foregut Vasculature -
Foote, A.P., Klotz, J.L., Harmon, D.L., Bush, L.P., Strickland, J.R. 2010. Effect of Ergot Alkaloids on Bovine Foregut Vasculature. Kentucky Beef Report. pgs 33-36.
Ergot Alkaloids: Toxicokinetics and Vascular Effects in Grazing Animals -
Strickland, J.R., Aiken, G.E., Klotz, J.L., Flythe, M.D., Brown, K.R. 2010. Ergot Alkaloids: Toxicokinetics and Vascular Effects in Grazing Animals. International Symposium on Fungal Endophytes of Grasses. pp 103-104.
An Extract of Endophyte Infected Tall Fescue Seed Induces Vasoconstriction of Bovine Foregut Vasculature -
Foote, A.P., Klotz, J.L., Bush, L.P., Strickland, J.R., Harmon, D.L. 2010. An Extract of Endophyte Infected Tall Fescue Seed Induces Vasoconstriction of Bovine Foregut Vasculature. International Symposium on Fungal Endophytes of Grasses. pp 33-34.
Efficacy of a Fescue Seed Extract in Inducing Toxicosis in Cattle -
Koontz, A.F., Bush, L.P., Klotz, J.L., Mcleod, K.R., Harmon, D.L. 2010. Efficacy of a Fescue Seed Extract in Inducing Toxicosis in Cattle. International Symposium on Fungal Endophytes of Grasses. p 58.
A Simple Tall Fescue Seed Extraction and Partial Purification of Ergovaline -
Fannin, F., Ji, H., Klotz, J.L., Bush, L.P. 2010. A Simple Tall Fescue Seed Extraction and Partial Purification of Ergovaline. International Symposium on Fungal Endophytes of Grasses. p 31.
Antagonism of 5-hydroxytryptamine2A Receptor Results in Decreased Contractile Response of Bovine Lateral Saphenous Vein to Tall Fescue Alkaloids -
Klotz, J.L., Strickland, J.R., Bush, L.P., Kirch, B.H., Brown, K.R. 2010. Antagonism of 5-hydroxytryptamine2A Receptor Results in Decreased Contractile Response of Bovine Lateral Saphenous Vein to Tall Fescue Alkaloids. J. Anim. Sci. Vol. 88, E-Suppl. 2/J. Dairy Sci. Vol. 93, E-Suppl. 1/Poult. Sci. Vol. 89, E-Suppl. 1. pg 55.
Ergot alkaloids induce vasoconstriction of bovine foregut vasculature -
Foote, A.P., Klotz, J.L., Harmon, D.L., Bush, L.P., Strickland, J.R. 2010. Ergot alkaloids induce vasoconstriction of bovine foregut vasculature. J. Anim. Sci. 88( 2/J). Dairy Sci. Vol. 93(1)/Poult. Sci. 89(1):701.
Development of a fescue toxicosis model using a fescue seed extract -
Koontz, A.F., Bush, L.P., Klotz, J.L., Mcleod, K.R., Schrick, F.N., Harmon, D.L. 2010. Development of a fescue toxicosis model using a fescue seed extract. J. Anim. Sci. 88:(2/J). Dairy Sci. 93( 1)/Poult. Sci. 89(1):704.
Tall fescue alkaloids cause vasoconstriction in equine medial palmar artery and vein -
Klotz, J.L., Mcdowell, K.J. 2010. Tall fescue alkaloids cause vasoconstriction in equine medial palmar artery and vein. J. Anim. Sci. 88(2/J). Dairy Sci. 93(1)/Poult. Sci. 89(1):55.
Contractile response of fescue-naïve bovine lateral saphenous veins to increasing concentrations of tall fescue alkaloids -
Klotz, J.L., Kirch, B.H., Aiken, G.E., Bush, L.P., Strickland, J.R. 2009. Contractile Response of Fescue-Naïve Bovine Lateral Saphenous Veins to Increasing Concentrations of Tall Fescue Alkaloids. J Anim Sci. 88:408-415.
USDA - Kentucky Report (Annual Report to SERA-IEG 8, Tall Fescue Toxicosis/Endophyte Workshop) -
Klotz, J.L., Bush, L.P., Strickland, J.R., West, C.P., Dinkins, R.D. 2009. USDA - Kentucky Report (Annual Report to SERA-IEG 8, Tall Fescue Toxicosis/Endophyte Workshop). SERA-IEG 8. p 62-66.
Development and validation of a LC-MS method for quantitation of ergot alkaloids in lateral saphenous vein tissue -
Smith, D.L., Smith, L.L., Shafer, W.D., Klotz, J.L., Strickland, J.R. 2009. Development and validation of a LC-MS method for quantitation of ergot alkaloids in lateral saphenous vein tissue. Journal of Agricultural and Food Chemistry. 57:7213-7220.
Ergot Alkaloid-Induced Blood Vessel Dysfunction Contributes to Fescue Toxicosis -
Strickland, J.R., Aiken, G.E., Klotz, J.L. 2009. Ergot Alkaloid-Induced Blood Vessel Dysfunction Contributes to Fescue Toxicosis. Forage and Grazinglands. 4Nov09.
Bioaccumulation of Ergovaline in Bovine Lateral Saphenous Veins in Vitro -
Klotz, J.L., Kirch, B.H., Aiken, G.E., Bush, L.P., Strickland, J.R. 2009. Bioaccumulation of Ergovaline in Bovine Lateral Saphenous Veins in Vitro. J Anim Sci. 2009. 87:2437-2447.
Validation of Right Ruminal Vein and Artery as Models of Bovine Foregut Vasculature -
Klotz, J.L., Bush, L.P., Strickland, J.R. 2009. Validation of Right Ruminal Vein and Artery as Models of Bovine Foregut Vasculature. Joint Abstracts of the American Dairy Science and Society of Animal Science. 87,E-Supp 2. p.83(M257).
USDA - Kentucky Report (Annual Report to SERA-IEG 8, Tall Fescue Toxicosis/Endophyte Workshop) -
Klotz, J.L., Smith, L.L., Bush, L.P., Strickland, J.R. 2008. USDA - Kentucky Report (Annual Report to SERA-IEG 8, Tall Fescue Toxicosis/Endophyte Workshop). SERA-IEG 8. pgs 54-58.
Tennessee Report (Annual Report to SERA-IEG8 Tall Fescue Toxicosis/Endophyte Workshop) -
Norman, R., Lane, C.D., Fisher, A.E., Campbell, B.T., Schrick, F.N., Waller, J.C., Block, S.S., Kojima, C.J., Spiers, D.E., Klotz, J.L., Strickland, J.R., Bates, G.E., Riggins, J.C., Hopkins, F.M., Edwards, J.L., Prado, T. 2008. Tennessee Report (Annual Report to SERA-IEG8 Tall Fescue Toxicosis/Endophyte Workshop). SERA-IEG 8. Meeting Report pgs 110-121.
Growing steers grazing high versus low endophyte (Neotyphodium coenophialum)-infected tall fescue have reduced serum enzymes increased hepatic glucogenic enzymes and reduced liver and carcass mass -
Brown, K.R., Anderson, G.A., Son, K., Rentfrow, G., Bush, L.P., Klotz, J.L., Strickland, J.R., Boling, J.A., Matthews, J.C. 2009. Growing steers grazing high versus low endophyte (Neotyphodium coenophialum)-infected tall fescue have reduced serum enzymes, increasedhepatic glucogenic enzymes, and reduced liver and carcass tissue mass. J. Anim. Sci. 87:748-760.
Technical note: comparison between two tracing methods with ultrasonography to determine lumen area of the caudal artery in beef cattle -
Aiken, G.E., Klotz, J.L., Kirch, B.H., Strickland, J.R., Boykin, D.L. 2008. Technical note: Comparison between two tracing methods with ultrasonography to determine lumen area of the caudal artery in beef cattle. Journal of Animal Science. 87:371-374.
Grazing Endophyte-Infected Tall Fescue Alters Serotonin Receptor-Induced Contractility of Bovine Lateral Saphenous Veins -
Klotz, J.L., Brown, K.R., Xue, Y., Matthews, J.C., Boling, J.A., Bush, L.P., Strickland, J.R. 2008. Grazing Endophyte-Infected Tall Fescue Alters Serotonin Receptor-Induced Contractility of Bovine Lateral Saphenous Veins. J. Anim. Sci. Vol. 86. p 102.
Steers Grazing Toxic Neotyphodium Coenophialum-Infected Forages Have Increased Hepatic Gluconeogenic Capacity -
Brown, K.R., Klotz, J.L., Strickland, J.R., Bush, L.P., Boling, J.A., Matthews, J.C. 2008. Steers Grazing Toxic Neotyphodium Coenophialum-Infected Forages Have Increased Hepatic Gluconeogenic Capacity. J. .Anim. Sci. Vol. 86, E-Suppl. 2. p 101.
The Effect of Toxic Tall Fescue on Cellobiose-Utilizing Populations in the Bovine Rumen -
Flythe, M.D., Gellin, G.L., Klotz, J.L., Strickland, J.R., Brown, K.R., Matthews, J.C., Boling, J.A. 2008. The Effect of Toxic Tall Fescue on Cellobiose-Utilizing Populations in the Bovine Rumen. American Society for Microbiology Annual Meeting. ISBN 978-1555814939. Z-040 (Abstract CD).
Effects of Selected Combinations of Tall Fescue Alkaloids on the Vasoconstrictive Capacity of Fescue-Naive Bovine Lateral Saphenous Veins -
Klotz, J.L., Kirch, B.H., Aiken, G.E., Bush, L.P., Strickland, J.R. 2008. Effects of Selected Combinations of Tall Fescue Alkaloids on the Vasoconstrictive Capacity of Fescue-Naive Bovine Lateral Saphenous Veins. Journal of Animal Science. 2008. 86:1021-1028.
Ergot Alkaloid Effects on Animal Physiology -
Strickland, J.R., Kirch, B.H., Klotz, J.L., Smith, L.L., Aiken, G.E., Flythe, M.D. 2008. Ergot Alkaloid Effects on Animal Physiology. Society for Range Management Meeting Abstracts. Published on Compact Disc, distributed at meeting; Abstract #1843. (http://srm.confex.com/srm/2008/techprogram/P1843.HTM).
USDA Kentucky Report -
Strickland, J.R., Dinkins, R.D., Aiken, G.E., Klotz, J.L., Kirch, B.H., Smith, L.L., Barnes, A.J., Waters, W.J., Bush, L.P., Brown, K.R., Matthews, J.C., Boling, J.A. 2007. Usda Kentucky report. SERA-IEG 8. pgs 159-178.
Ergovaline-induced vasoconstriction in an isolated bovine lateral saphenous vein bioassay -
Klotz, J.L., Bush, L.P., Smith, D.L., Shafer, W.D., Smith, L.L., Arrington, B.C., Strickland, J.R. 2007. Ergovaline-induced vasoconstriction in an isolated bovine lateral saphenous vein bioassay. Journal of Animal Science. 85:2330-2336.
Separation and Quantitation of Seven Ergot Alkaloids in Bovine Vein Tissue -
Shafer, W.D., Smith, D.L., Smith, L.L., Klotz, J.L., Strickland, J.R. 2007. Separation and Quantitation of Seven Ergot Alkaloids in Bovine Vein Tissue. Proceedings of the ASMS Conference on Mass Spectrometry and Allied Topics, June 3-7, 2007. #ThPh-118.
Grazing High Versus Low Endophyte-Infected Tall Fescue Reduces Contractility of Bovine Lateral Saphenous Veins -
Klotz, J.L., Brown, K.R., Matthews, J.C., Boling, J.A., Bush, L.P., Strickland, J.R. 2007. Grazing High Versus Low Endophyte-Infected Tall Fescue Reduces Contractility of Bovine Lateral Saphenous Veins. J. Anim. Sci. Vol. 85, Suppl. 1/J. Dairy Scit. Vol. 90, SUppl. 1/Poult. Sci. Vol. 86 Suppl 1. pg 12-13.
Ergocryptine and Ergonovine Induced Contractile Responses in Fescue Naive Bovine Lateral Saphenous Veins -
Klotz, J.L., Kirch, B.H., Aiken, G.E., Arrington, B.C., Bush, L.P., Strickland, J.R. 2007. Ergocryptine and Ergonovine Induced Contractile Responses in Fescue Naive Bovine Lateral Saphenous Veins. J. Anim. Sci. Vol. 85, Suppl. 1/J. Dairy Scit. Vol. 90, SUppl. 1/Poult. Sci. Vol. 86 Suppl 1. pg 13.
Neotyphodium Coenophialum Alters Blood Metabolites Involved in Nitrogen, Energy, and Minteral Metabolism in Growing Steers -
Brown, K.R., Harrison, L.R., Klotz, J.L., Strickland, J.R., Boling, J.A., Matthews, J.C. 2007. Neotyphodium Coenophialum Alters Blood Metavolites Involved in Nitrogen, Energy, and Minteral Metabolism in Growing Steers. J. Anim. Sci. Vol. 85, Suppl. 1/J. Dairy Scit. Vol. 90, SUppl. 1/Poult. Sci. Vol. 86 Suppl 1. pg 418.
Changes in net portal nutrient flux in response to weaning transition and ionohore supplementation in dairy calves -
Klotz, J.L., Heitmann, R.N. 2007. Changes in net portal nutrient flux in response to weaning transition and ionohore supplementation in dairy calves. Journal of Dairy Science. 90:1326-1339.
USDA-Kentucky Report: Forage-Animal Production Research Unit (FAPRU) Investigations: Tall Fescue Alkaloids and Toxicosis -
Strickland, J.R., Aiken, G.E., Dinkins, R.D., Klotz, J.L., Kirch, B.H., Smith, L.L., Looper, M.L., Bush, L.P., Arrington, B.C., Smith, D.L., Shafer, W.D., Schardl, C., Hesse, U. 2006. Usda-Kentucky Report: Forage-Animal Production Research Unit (FAPRU) Investigations: Tall Fescue Alkaloids and Toxicosis. SERA-IEG 8. Annual Report: pgs. 97-111.
Assessment of Vasoconstrictive Capacity of Tall Fescue Alkaloids Using Fescue Naive Lateral Saphenous Veins of Crossbreed Heifer Cattle -
Klotz, J.L., Kirch, B.H., Aiken, G.E., Bush, L.P., Strickland, J.R., Arrington, B.C. 2007. Assessment of Vasoconstrictive Capacity of Tall Fescue Alkaloids Using Fescue Naive Lateral Saphenous Veins of Crossbreed Heifer Cattle. Proceedings of the 6th International Symposium on Fungal Endophytes of Grasses. Grassland Research and Practice Series No. 13:383-385.
ASSESSMENT OF VASOCONSTRICTIVE POTENTIAL OF D-LYSERGIC ACID USING AN ISOLATED BOVINE LATERAL SAPHENOUS VEIN BIOASSAY -
Klotz, J.L., Bush, L.P., Smith, D.L., Schafer, W.D., Smith, L.L., Vevoda, A.O., Craig, A.M., Arrington, B.C., Strickland, J.R. 2006. Assessment of vasoconstrictive potential of d-lysergic acid using an isolated bovine lateral saphenous vein bioassay. Journal of Animal Science. 84:3167-3175.
Monitoring the presence of ergot alkaloids in forage animal samples -
Smith, D.L., Shafer, W.D., Smith, L.L., Klotz, J.L., Strickland, J.R. 2006. Monitoring the presence of ergot alkaloids in forage animal samples. American Society for Mass Spectrometry. Proceedings of the 54th ASMS Conference.
GROSS AND HISTOPATHOLOGICAL OBSERVATIONS OF LONG TERM CATHETERIZED VESSELS IN EXPERIMENTAL SHEEP -
Barraza, M.L., Strickland, J.R., Zepada, H., Taylor, J.B., Krehbiel, C.R., Bell, G.S., Koltz, J.L., 2006. Gross and histopathological observations of long term catheterized vessels in experimental sheep. Journal of Veterinary Medicine. 53:230-238 (2006).
Evaluation of the Vasoconstrictive Capacity of Tall Fescue Alkaloids Using Fescue Naive Bovine Lateral Saphenous Veins -
Klotz, J.L., Kirch, B.H., Aiken, G.E., Bush, L.P., Arrington, B.C., Strickland, J.R. 2006. Evaluation of the Vasoconstrictive Capacity of Tall Fescue Alkaloids Using Fescue Naive Bovine Lateral Saphenous Veins. Journal of Animal Science Supplement. 84:54.
Response of Bovine Lateral Saphenous Vein to Increasing Concentrations of Lysergic Acid and Ergovaline -
Klotz, J.L., Arrington, B.C., Bush, L.P., Strickland, J.R. 2006. Response of Bovine Lateral Saphenous Vein to Increasing Concentrations of Lysergic Acid and Ergovaline. Journal of Animal Science Supplement. 84:53-54.
EFFECTS OF WEANING AND INOPHORE SUPPLEMENTATION ON SELECTED BLOOD METABOLITES AND GROWTH IN DAIRY CALVES -
Klotz, J.L., Heitmann, R.N. 2006. Effects of weaning and inophore supplementation on selected blood metabolites and growth in dairy calves. Journal of Dairy Science. 89:3587-3598.
ANNUAL PROGRESS REPORT FOR USDA-ARS-FAPRU TO SERAIEG 8 TALL FESCUE TOXICOSIS/ENDOPHYTE WORKSHOP -
Klotz, J.L., Schafer, W.D., Smith, D.K., Smith, L.L., Arrington, B.C., Bush, L.P., Strickland, J.R., Aiken, G.E., Schardl, S., Hesse, U., Dinkins, R.D. 2005. Annual progress report for USDA-ARS-FAPRU to SERA-IEG 8 Tall Fescue Toxicosis/Endophyte Workshop. Meeting Proceedings. pgs 30-36.
Clearance of Para-Aminohippuric Acid in Wethers Consuming Locoweed -
Strickland, J.R., Custis, M., Ashley, A.K., Smith, L.L., Klotz, J.L., Krehbiel, C. 2005. Clearance of Para-Aminohippuric Acid in Wethers Consuming Locoweed. New Zealand Veterinary Journal. 53(5):288-292.
Effects of Limb Origin and Twenty-four Hour Storage on Contractile Response of Bovine Lateral Saphenous Vein to Norepinephrine -
Klotz, J.L., Sevold, A., Bush, L., Strickland, J.R. 2005. Effects of Limb Origin and Twenty-four Hour Storage on Contractile Response of Bovine Lateral Saphenous Vein to Norepinephrine. Journal of Animal Science. 83:299.
ARS News Articles
Last Modified: 5/2/2016
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