|Title: Method to Control Insect Reproduction for Insect Control|
US Patent Office Full Record
The invention relates to novel pseudopeptide analogs from the insect allatostatin neuropeptide family, which possess biological activity that mimic naturally occurring neuropeptides. By adding a hydrophobic moiety to an active portion of the allatostatin peptides, analogs are produced which exhibit an overall amphiphilic nature and which are capable of penetrating the insect cuticle while still retaining biological activity. By substituting sterically hindered amino acids or aromatic acids for any or all of the second, third, or fifth amino acid residues of the allatostatic C-terminal pentapeptide, analogs have been produced which are resistant to degradation by insect peptidases while still retaining biological activity. The analogs may be used for insect control by disrupting critical reproductive and/or developmental processes normally regulated by allatostatins in insects.
Please refer to USPN 7,078,384 (Docket #0062.03). AMimetic Insect Allatostatin Analogs for Insect Control,@ which issued on July 18, 2006, and is a divisional of USPN 6,664,371 (Docket #0239.00), which issued on December 16, 2003, and is a divisional of USPN 6,207,643 (Docket #0047.99), which issued on March 27, 2001.
Foreign rights are not available.