Start Date: May 27, 2005
End Date: May 26, 2010
Isolate chemical mixtures by aeration or direct extraction of insects and plants. Separate components of mixtures using chromatography and determine active compounds using coupled GC-electroantennogram detection and behavioral bioassays. Identify chemical structures using coupled chromatography-mass spectrometry and other spectral means. Verify identifications by synthesis or by comparison to commercial standards, and evaluate active chemicals in the laboratory and field. Characterize neural mechanisms used by targeted species to detect chemical signals. Determine processes regulating synthesis and release of insect and plant signals in order to improve their effectiveness and provide insight into novel approaches.