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United States Department of Agriculture

Agricultural Research Service

Research Project: Chemistry of Natural Products for Nutraceutical Use, Pest Management and Crop Development

Location: Natural Products Utilization Research

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)

Dual extraction of essential oil and podophyllotoxin from creeping juniper (Juniperus horizontalis) - (Peer Reviewed Journal)
Cantrell, C.L., Zheljazkov, V.D., Carvalho, C.R., Astatkie, T., Jeliazkova, E.A., Rosa, L. 2014. Dual extraction of essential oil and podophyllotoxin from creeping juniper (Juniperus horizontalis). PLoS One. 9(9):e106057.
Molecular and phytochemical investigation of Angelica dahurica and Aneelica pubescentis essential oils and their biological activity against Aedes aegypti, Stephanitis pyrioides and Colletotrichum species - (Peer Reviewed Journal)
Tabanca, N., Gao, Z., Demirci, B., Techen, N., Wedge, D.E., Ali, A., Sampson, B.J., Werle, C.T., Bernier, U.R., Khan, I.A., Can Baser, K.H. 2014. Molecular and phytochemical investigation of Angelica dahurica and Aneelica pubescentis essential oils and their biological activity against Aedes aegypti, Stephanitis pyrioides and Colletotrichum species. Journal of Agricultural and Food Chemistry. 62:8848-8857.
Chemical composition and biological effects of Artemisia maritima and Artemisia nilagirica essential oils from wild plant of Western Himalaya - (Peer Reviewed Journal)
Stappen, I., Wanner, J., Tabanca, N., Wedge, D.E., Ali, A., Khan, I.A., Kaul, V.K., Lal, B., Jaitak, V., Gochev, V., Girova, T., Stoyanova, A., Schmidt, E., Jirovetz, L. 2014. Chemical composition and biological effects of Artemisia maritima and Artemisia nilagirica essential oils from wild plant of Western Himalaya. Planta Medica. 80:1079-1087.
Antibacterial activity of acylglucinol derivatives against Flavobacterium columnare - (Peer Reviewed Journal)
Meepagala, K.M., Schrader, K. 2014. Antibacterial activity of acylglucinol derivatives against Flavobacterium columnare. Journal of Agricultural Chemistry and Environment. 3:89-95.
Fatty acid synthase methylation levels in adipose tissue: effects of an obesogenic diet and phenolic compounds - (Peer Reviewed Journal)
Gracia, A., Elcoroaristizabal, X., Fernandez-Quintela, A., Miranda, J., Bediaga, N.G., De Pancorbo, M.M., Rimando, A.M., Portillo, M.P. 2014. Fatty acid synthase methylation levels in adipose tissue: effects of an obesogenic diet and phenolic compounds. Genes and Nutrition. 9:411. DOI 10.1007/s12263-014-0411-9.
Inuloxins A-D and derivatives as antileishmanial agents: structure-activity relationship study - (Peer Reviewed Journal)
Avolio, F., Rimando, A.M., Cimmino, A., Andolfi, A., Jain, S., Tekwani, B.L., Evidente, A. 2014. Inuloxins A-D and derivatives as antileishmanial agents: structure-activity relationship study. Journal of Antibiotics. 67(8):597-601.
Steam distillation extraction kinetics regression models to predict essential oil yield, composition, and bioactivity of chamomile oil - (Peer Reviewed Journal)
Gawde, A., Cantrell, C.L., Zheljazkov, V.D., Astatkie, T., Schlegel, V. 2014. Steam distillation extraction kinetics regression models to predict essential oil yield, composition, and bioactivity of chamomile oil. Industrial Crops and Products. 58:61-67.
Pharmacological activities of cilantro’s aliphatic Aldehydes against leishmania donovani - (Peer Reviewed Journal)
(21-Mar-14)
Chemical and biological diversity of the volatiles of five Artemisia species from far east of Russia - (Peer Reviewed Journal)
Ozek, G., Suleimen, Y., Tabanca, N., Doudkin, R., Gorovoy, P.G., Goger, F., Wedge, D.E., Ali, A., Khan, I.A., Baser, K. 2014. Chemical and biological diversity of the volatiles of five Artemisia species from far east of Russia. Records of Natural Products. 8(3):242-261.
The effect of coal-bed methane water on spearmint and peppermint - (Peer Reviewed Journal)
Zheljazkov, V.D., Cantrell, C.L., Astatkie, T., Schlegel, V., Jeliazkova, E., Lowe, D. 2014. The effect of coal-bed methane water on spearmint and peppermint. Journal of Environmental Quality. 42:1815-1821.
Nutrient uptake, biomass yield and quantitative analysis of aliphatic aldehydes in cilantro plants - (Peer Reviewed Journal)
Donega, M.A., Mello, S.C., Moraes, R.M., Cantrell, C.L. 2013. Nutrient uptake, biomass yield and quantitative analysis of aliphatic aldehydes in cilantro plants. Industrial Crops and Products. 44:127-131.
Human health and transgenic crops - (Other)
Rimando, A.M., Duke, S.O. 2013. Human health and transgenic crops. Journal of Agricultural and Food Chemistry. 61:11693-11694.
Human health and transgenic crops - (Other)
Rimando, A.M., Duke, S.O. 2013. Human health and transgenic crops. Journal of Agricultural and Food Chemistry. 61:11693-11694.
Toxicity of thiophenes from echinops transiliensis (Asteraceae) against aedes aegypti (Diptera: Culicidae) larvae - (Peer Reviewed Journal)
Nakano, H., Ali, A., Rehman, J., Mamonov, L., Cantrell, C.L., Khan, I.A. 2014. Toxicity of thiophenes from echinops transiliensis (Asteraceae) against aedes aegypti (Diptera: Culicidae) larvae. Chemistry and Biodiversity. 11(7):1001-1009.
Antibacterial compounds from Rutaceae with activities against Flavobacterium columnare and Streptococcus iniae - (Peer Reviewed Journal)
Meepagala, K.M., Schrader, K., Burandt, C. 2013. Antibacterial compounds from Rutaceae with activities against Flavobacterium columnare and Streptococcus iniae. Journal of Agricultural Chemistry and Environment. 2(4):90-100.
Effect of harvest timing on leaf production and yield of diterpene glycosides in Stevia rebaudiana Bert: a specialty perennial crop for Mississippi - (Peer Reviewed Journal)
Moraes, R.M., Donega, M.A., Cantrell, C.L., Mello, S.C., Mcchesney, J.D. 2013. Effect of harvest timing on leaf production and yield of diterpene glycosides in Stevia rebaudiana Bert: a specialty perennial crop for Mississippi. Industrial Crops and Products. 51:385-389.
Coniochaeta ligniaria: antifungal activity of the cryptic endophytic fungus associated with autotrophic cultures of the medicinal plant Smallanthus sonchifolius (Asteraceae) - (Peer Reviewed Journal)
Rosa, L., Quieroz, S., Moraes, R., Wang, X., Techen, N., Pan, Z., Cantrell, C.L., Wedge, D.E. 2013. Coniochaeta ligniaria: antifungal activity of the cryptic endophytic fungus associated with autotrophic cultures of the medicinal plant Smallanthus sonchifolius (Asteraceae). Symbiosis. 60:133-142.
Mentha canadensis L., a subtropical plant can withstand first few fall frost when grown in northern climate - (Peer Reviewed Journal)
Zheljazhov, V.D., Cantrell, C.L., Astatkie, T., Jeliazkova, E. 2013. Mentha canadensis L., a subtropical plant can withstand first few fall frost when grown in northern climate. Industrial Crops and Products. 49:521-525.
Anxiolytic action of pterostilbene: involvement of hippocampal ERK phosphorylation - (Peer Reviewed Journal)
Rahim, A., Rimando, A.M., Silistrel, K., El-Alfy, A.T. 2013. Anxiolytic action of pterostilbene: involvement of hippocampal ERK phosphorylation. Planta Medica. 19:723-730.
Distribution, diversity and bioprospecting of bioactive compounds from cryptic fungal communities associated with endemic and cold-adapted macroalgae in Antarctica - (Peer Reviewed Journal)
Godinho, V.M., Esteves, L.F., Santiago, T., Pellizari, F.M., Yokoya, N., Pupo, D., Alves, T., Sales, J., Romanha, A.J., Zani, C.L., Cantrell, C.L., Rosa, C.A., Rosa, L.H. 2013. Diversity and bioprospecting of fungal communities associated with endemic and cold-adapted macroalgae in Antarctica. The ISME Journal: Multidisciplinary Journal of Microbial Ecology. 7:1434-1451.
Harvesting number and timing effects on shoot yield and flavonoid content in American skullcap (Scutellaria lateriflora) - (Peer Reviewed Journal)
Shiwakoti, S., Shannon, D.A., Wood, W., Lawrence, K.S., Kemppainen, B., Joshee, N., Rimando, A.M. 2013. Harvesting number and timing effects on shoot yield and flavonoid content in American skullcap (Scutellaria lateriflora) . Journal of Herbs, Spices and Medicinal Plants. 19:248-261.
Synthesis and biological activity of substituted urea and thiourea derivatives containing 1,2,4-triazole moiety - (Peer Reviewed Journal)
Kaymakcioglu, B., Celen, A.O., Nurhayat, T., Abbas, A., Khan, S.I., Khan, I.A., Wedge, D.E. 2013. Synthesis and biological activity of substituted urea and thiourea derivatives containing 1,2,4-triazole moiety. Molecules. 18(3):3562-3576.
Proceedings of the frst joint american chemical society agricultural and food chemistry division – american chemical society international chemical sciences chapter in Thailand symposium on agricultural and food chemistry - (Proceedings)
Mahatanatawee, K., Rimando, A.M. 2014. In:Proceedings of the first joint american chemical society agricultural and food chemistry division – american chemical society international chemical sciences chapter in Thailand symposium on agricultural and food chemistry, March 4-5, 2014, Bangkok, Thialand, p.355.
Antifungal activity against plant pathogens of metabolites from the endophytic fungus Cladosporium cladosporioides - (Peer Reviewed Journal)
Wang, X., Radwan, M.M., Tarawneh, A.H., Gao, J., Wedge, D.E., Rosa, L.G., Cutler, H., Cutler, S. 2013. Antifungal activity against plant pathogens of metabolites from the endophytic fungus Cladosporium cladosporioides. Journal of Agricultural and Food Chemistry. 61(19):4551-4555.
Trimethoxy-resveratrol and piceatannol administered orally suppress and inhibit tumor formation and growth in prostate cancer xenografts - (Peer Reviewed Journal)
Dias, S.J., Li, K., Rimando, A.M., Dhar, S., Mizuno, C.S., Penman, A.D., Levenson, A.S. 2013. Trimethoxy-resveratrol and piceatannol administered orally suppress and inhibit tumor formation and growth in prostate cancer xenografts. The Prostate Journal. 73:1135-1146.
Pterostilbene acts through metastasis-associated protein 1 to inhibit tumor progression and metastasis in prostate cancer - (Peer Reviewed Journal)
Kun, L., Dias, S.J., Rimando, A.M., Dhar, S., Mizuno, C.S., Penman, A.D., Lewin, J.R., Levenson, A.S. 2013. Pterostilbene acts through metastasis-associated protein 1 to inhibit tumor progression and metastasis in prostate cancer. PLoS One. 8(3):e557542.
Insecticidal and biting deterrent activity of rose-scented geranium (Pelargonium spp.) essential oils and individual compounds against Stephanitis pyrioides and Aedes aegypti - (Peer Reviewed Journal)
Ali, A., Murphy, C., Demirci, B., Wedge, D.E., Sampson, B., Khan, I.A., Baser, H., Tabanca, N. 2013. Insecticidal and biting deterrent activity of rose-scented geranium (Pelargonium spp.) essential oils and individual compounds against Stephanitis pyrioides and Aedes aegypti. Pest Management Science. DOI 10.1002/ps.3518.
Composition, mosquito larvicidal, biting deterrent and antifungal activity of essential oils of different plant parts of Cupressus arizonica var. glabra (Carolina Sapphire) - (Peer Reviewed Journal)
Ali, A., Tabanca, N., Demirci, B., Baser, K., Ellis, J., Gray, S., Lackey, B., Murphy, C., Khan, I.A., Wedge, D.E. 2013. Composition, mosquito larvicidal, biting deterrent and antifungal activity of essential oils of different plant parts of Cupressus arizonica var. glabra (Carolina Sapphire). Natural Product Communications. 8(2):257-260.
Anti-cancer scopes and associated mechanisms of Scutellaria extract and flavonoid wogonin - (Peer Reviewed Journal)
Patel, P., Joshee, N., Rimando, A.M., Parajuli, P. 2013. Anti-cancer scopes and associated mechanisms of Scutellaria extract and flavonoid wogonin. Current Cancer Therapy Reviews. 9(1):34-42.
Distillation time effect on lavender essential oil yield and composition - (Peer Reviewed Journal)
Zheljazkov, V.D., Cantrell, C.L., Astatkie, T., Jeliazkova, E. 2013. Distillation time effect on lavender essential oil yield and composition. Journal Oleo Science. 62(4):195-199.
Bioprospecting for podophyllotoxin in the Big Horn Mountains, Wyoming - (Peer Reviewed Journal)
Zhelijazkov, V.D., Cantrell, C.L., Donega, M.A., Astatkie, T. 2013. Bioprospecting for podophyllotoxin in the Big Horn Mountains, Wyoming. Industrial Crops and Products. 43:787-790.
Fall frosts effects on the essential oil of “Native” spearmint in Wyoming - (Peer Reviewed Journal)
Zheljazkov, V.D., Cantrell, C.L., Astatkie, T., Jeliazkova, E. 2012. Fall frosts effects on the essential oil of “Native” spearmint in Wyoming. Industrial Crops and Products. 47(11):1603-1606.
Aedes aegypti (Diptera: culicidae) biting deterrence: structure-activity relationship of saturated and unsaturated fatty acids - (Peer Reviewed Journal)
Ali, A., Cantrell, C.L., Bernier, U.R., Duke, S.O., Schneider, J.C., Agramonte, N.M., Khan, I. 2012. Aedes aegypti (Diptera: culicidae) biting deterrence: structure-activity relationship of saturated and unsaturated fatty acids. Journal of Medical Entomology. 49:1370-1378.
Phytotoxic furanocoumarins from the shoots of Semenovia transiliensis Regel & Herder - (Peer Reviewed Journal)
Sondhia, S., Duke, S.O., Green III., S., Gemejiyeva, N.G., Mamonov, L.K., Cantrell, C.L. 2012. Phytotoxic furanocoumarins from the shoots of Semenovia transiliensis Regel & Herder. Natural Product Communications. 7(10):1327-1330.
Diversity and biological activities of endophytic fungi associated with micropropagated medicinal plant Echinacea purpurea (L.) Moench - (Peer Reviewed Journal)
Rosa, L.H., Tabanca, N., Techen, N., Wedge, D.E., Pan, Z., Bernier, U.R., Becnel, J.J., Agramonte, N.M., Walker, L., Moraes, R. 2012. Diversity and biological activities of endophytic fungi associated with micropropagated medicinal plant Echinacea purpurea (L.) Moench. American Journal of Plant Sciences. 3:1105-1114.
Design synthesis and evaluation of the inhibitory selectivity of novel trans-resveratrol analogues on human recombinant CYP1A1 CYP1A2 and CYP1B1 - (Peer Reviewed Journal)
Mikstacka, R., Rimando, A.M., Dutkiewicz, Z., Stefanski, T., Sobiak, S. 2012. Design synthesis and evaluation of the inhibitory selectivity of novel trans-resveratrol analogues on human recombinant CYP1A1 CYP1A2 and CYP1B1. Bioorganic and Medicinal Chemistry. 20(17):5117-2126.
Chemical constituents from Echinops nanus and Echinops transiliensis - (Peer Reviewed Journal)
Nakano, H., Cantrell, C.L., Mamonov, L.K., Kustova, T.S., Fronczek, F.R., Ross, S.A. 2012. Chemical constituents from Echinops nanus and Echinops transiliensis. Biochemical Systematics and Ecology. 45:127-129.
Serviceberry [Amerlanchier alnifolia (Nutt.) Nutt. ex. M. Roem(Rosaceae)] leaf exhibits mammalian alpha glucosidase activity and suppresses postprandial glycemic response in a mouse model of diet induced obesity/hyperglycemia - (Peer Reviewed Journal)
Zhang, A., Rimando, A.M., Fish, W., Mentreddy, S.R., Mathews, S. 2012. Serviceberry [Amerlanchier alnifolia (Nutt.) Nutt. ex. M. Roem(Rosaceae)] leaf exhibits mammalian alpha glucosidase activity and suppresses postprandial glycemic response in a mouse model of diet induced obesity/hyperglycemia. Journal of Ethnopharmacology. 143(2):481-487.
Antifungal activity of extracts from endophytic fungi associated with Smallanthus maintained in vitro as autotrophic cultures and as pot plants in the greenhouse - (Peer Reviewed Journal)
Rosa, L., Tabanca, N., Techen, N., Pan, Z., Wedge, D.E., Moraes, R. 2012. Antifungal activity of extracts from endophytic fungi associated with Smallanthus maintained in vitro as autotrophic cultures and as pot plants in the greenhouse. Canadian Journal of Microbiology. 58:1202-1211.
Natural products as sources for new pesticides - (Review Article)
Cantrell, C.L., Dayan, F.E., Duke, S.O. 2012. Natural products as sources for new pesticides. Journal of Natural Products. 75(6):1231-1242.
Bioassay-directed isolation and identification of phytotoxic and fungitoxic acetylenes from Conyza canadensis - (Peer Reviewed Journal)
Queiroz, S.C., Cantrell, C.L., Duke, S.O., Wedge, D.E., Nandula, V.K., Moraes, R.M., Cerdeira, A.L. 2012. Bioassay-directed isolation and identification of phytotoxic and fungitoxic acetylenes from Conyza canadensis. Journal of Agricultural and Food Chemistry. 60:5893-5898.
Modification of yield and composition of essential oils by distillation time - (Peer Reviewed Journal)
Cannon, J.B., Cantrell, C.L., Astatkie, T., Zheljazkov, V.D. 2012. Modification of yield and composition of essential oils by distillation time. Industrial Crops and Products. 41:214-220.
Scutellaria: traditional uses, medicinal properties, biotechnology and potential as a commercial crop - (Book / Chapter)
Joshee, N., Tascan, A., Medina-Bolivar, F., Parajuli, P., Rimando, A.M., Shannon, D.A., Adelberg, J.W. 2012. Scutellaria: traditional uses, medicinal properties, biotechnology and potential as a commercial crop. Book Chapter. 69-99.
One-step multiple component isolation from the oil of Crinitaria tatarica (Less) Sojak by preparative capillary gas chromatography with characterization by spectroscopic and spectrometric techniques - (Peer Reviewed Journal)
Ozek, G., Ishmuratova, M., Tabanca, N., Radwan, M.M., Goger, F., Ozek, T., Wedge, D.E., Becnel, J.J., Cutler, S.J., Baser, K. 2012. One-step multiple component isolation from the oil of Crinitaria tatarica (Less) Sojak by preparative capillary gas chromatography with characterization by spectroscopic and spectrometric techniques. Journal of Separation Science. 35:650-660.
One-step multiple component isolation from the oil of Crinitaria tatarica (Less.) Sojak. by preparative capillary gas with characterization by spectroscopic and spectrometric techniques and evaluation of biological activity - (Peer Reviewed Journal)
Ozek, G., Ishmuratova, M., Tabanca, N., Radwan, M.M., Goger, F., Ozek, T., Wedge, D.E., Becnel, J.J., Cutler, S.J., Baser, K.H. 2012. One-step multiple component isolation from the oil of Crinitaria tatarica (Less.) Sojak. by preparative capillary GC with characterization by spectroscopic and spectrometric techniques and evaluation of biological activity. Journal of Separation Science. 35(5-6):650-660.
Scutellaria flavonoids inhibit tumor-mediated induction of Treg cells via inhibition of TGF-ß1 activity - (Peer Reviewed Journal)
Dandawate, S., Williams, L., Joshee, N., Rimando, A.M., Mittal, S., Thakur, A., Lum, L., Parajuli, P. 2011. Scutellaria flavonoids inhibit tumor-mediated induction of Treg cells via inhibition of TGF-ß1 activity. Cancer Immunology and Immunotherapy. 61:701-711.
Synthesis and biological activity of hydrazide hydrazones and their corresponding 3-acetyl-2,5-disubstituted-2,3-dihydro-1,3,4-oxadiazoles - (Peer Reviewed Journal)
Kocyigit-Kaymakciogl, U., Oruc-Emre, E., Unsalan, S., Iscan, G., Demirci, F., Rollas, S., Tabanca, N., Wedge, D.E., Khan, S.I. 2011. Synthesis and biological activity of hydrazide hydrazones and their corresponding 3-acetyl-2,5-disubstituted-2,3-dihydro-1,3,4-oxadiazoles. Bioorganic and Medicinal Chemistry. 1-10.
Echinopsacetylenes A and B, new thiophenes from Echinops transiliensis - (Peer Reviewed Journal)
Nakano, H., Cantrell, C.L., Mamonov, L.K., Osbrink, W.L., Ross, S. 2011. Echinopsacetylenes A and B, new thiophenes from Echinops transiliensis. Organic Letters. 13(23):6228-6231.
Low-dose pterostilbene but not resveratrol is a potent neuromodulator in aging and Alzheimer’s Disease - (Peer Reviewed Journal)
Chang, J., Rimando, A.M., Pallas, M., Camins, A., Porquet, D., Reeves, J., Shukitt Hale, B., Smith, M.A., Joseph, J.A., Casadesus, G. 2011. Low-dose pterostilbene but not resveratrol is a potent neuromodulator in aging and Alzheimer’s Disease. Neurobiology of Aging. 33:2062-2071.
Activity of lycorine analogs against the fish bacterial pathogen Flavobacterium columnare - (Peer Reviewed Journal)
Tan, C., Schrader, K., Mizuno, C.S., Rimando, A.M. 2011. Activity of lycorine analogs against the fish bacterial pathogen Flavobacterium columnare. Journal of Agricultural & Food Chemistry. 59:5977-5985.
Lemongrass productivity oil content and composition as a function of nitrogen sulfur and harvest time - (Peer Reviewed Journal)
Zheljazkov, V.D., Cantrell, C.L., Astatkie, T., Cannon, J.B. 2011. Lemongrass productivity oil content and composition as a function of nitrogen sulfur and harvest time. Agronomy Journal. 103(3):805-812.
Synthesis of (-)-callicarpenal a natural arthropod-repellent terpenoid - (Peer Reviewed Journal)
Ling, T., Xu, J., Smith, R., Ali, A., Cantrell, C.L., Theodorakis, E.A. 2011. Synthesis of (-)-callicarpenal a natural arthropod-repellent terpenoid. Tetrahedron. 67:3023-3029.
Identification of the mosquito biting deterrent constituents from the Indian folk remedy plant Jatropha curcas - (Peer Reviewed Journal)
Cantrell, C.L., Ali, A., Duke, S.O., Khan, I. 2011. Identification of the mosquito biting deterrent constituents from the Indian folk remedy plant Jatropha curcas. Journal of Medical Entomology. 48(4):836-845.
Scutellaria biotechnology: Achievements and future prospects - (Proceedings)
Joshee, N., Prahlad, P., Medina-Bolivar, F., Rimando, A.M., Yadav, A.K. 2010. Scutellaria Biotechnology: Achievements and Future Prospects. Bulletin UASVM Horticulture. 67(1):1-10.
Last Modified: 10/25/2014
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