Publications (Clicking on the reprint icon will take you to the publication reprint.)

A divergent picornavirus from a turkey with gastro-intestinal disease     - (Peer Reviewed Journal)

Ng, T.F.F., Cheung, A.K., Wong, W., Lager, K.M., Kondov, N.O., Cha, Y., Murphy, D.A., Pogranichniy, R.M., Delwart, E. 2013. Divergent picornavirus from a turkey with gastro-intestinal disease. Genome Announcements. 1(3):e00134-13.

Divergent immune responses and disease outcomes in piglets immunized with inactivated and attenuated H3N2 swine influenza vaccines in the presence of maternally-derived antibodies - (Abstract Only)

(14-Mar-13)

Increased diversity of H3N2 influenza virus in pigs in the United States and implications for pigs and humans - (Abstract Only)

(12-Mar-13)

Genotype patterns of contemporary reassorted H3N2 virus in U.S. swine - (Peer Reviewed Journal)

(06-Mar-13)

Pathogenicity and transmission of the novel A (H3N2v) influenza virus isolated from humans in experimentally inoculated pigs - (Abstract Only)

(15-Feb-13)

The use of epitope tags in modified porcine respiratory and reproductive syndrome virus vaccines to differentiate infected from vaccinated animals - (Abstract Only)

Spear, A.R., Lager, K.M., Faaberg, K.S. 2013. The use of epitope tags in modified porcine respiratory and reproductive syndrome virus vaccines to differentiate infected from vaccinated animals. Positive Strand RNA Viruses, Keystone Symposia on Molecular and Cellular Biology. Paper No. 2079, p. 94.

Reactomes of porcine alveolar macrophages infected with porcine reproductive and respiratory syndrome virus     - (Peer Reviewed Journal)

Jiang, Z., Zhou, X., Michal, J.J., Wu, X.-L., Zhang, L., Zhang, M., Ding, B., Liu, B., Manoranjan, V.S., Neill, J.D., Harhay, G.P., Kehrli, Jr., M.E., Miller, L.C. 2013. Reactomes of porcine alveolar macrophages infected with porcine reproductive and respiratory syndrome virus. PLoS One. 8(3):e59229.

Functions of Rep and Rep' during porcine circovirus rolling-circle replication - (Abstract Only)

Cheung, A.K. 2013. Functions of Rep and Rep' during porcine circovirus rolling-circle replication [abstract]. DNA Replication and Recombination - training for proteins involved in eukaryotic DNA replication, Keystone Symposium, March 3-8, 2013, Banff, Canada. Paper No. Abs. x5 1017. p. 80.

Comparative transcriptome response in swine tracheobronchial lymph nodes to viral infection - (Abstract Only)

Miller, L.C., Harhay, G.P., Kehrli, Jr., M.E., Lager, K.M. 2013. Comparative transcriptome response in swine tracheobronchial lymph nodes to viral infection [abstract]. International Plant & Animal Genome XXI, January 12-16, 2013, San Diego, California. Paper No. W756.

Antibody repertoire development in fetal and neonatal piglets. XV. Porcine circovirus type 2 infection differentially affects serum IgG levels and antibodies to ORF2 in piglets free from other environmental factors - (Peer Reviewed Journal)

Sun, X., Wertz, N., Lager, K.M., Butler, J.E. 2012. Antibody repertoire development in fetal and neonatal piglets. XV. Porcine circovirus type 2 infection differentially affects serum IgG levels and antibodies to ORF2 in piglets free from other environmental factors. Vaccine. 31(1):141-148.

Pathogenesis of HP-PRRSV in gnotobiotic pigs - (Abstract Only)

Lager, K.M., Faaberg, K.S., Brockmeier, S.L., Miller, L.C., Kappes, M.A., Spear, A., Kehrli, Jr., M.E. 2012. Pathogenesis of HP-PRRSV in gnotobiotic pigs. 2012 International PRRS Symposium. p. 92.

Swine tracheobronchial lymph node mRNA responses in swine infected with a highly pathogenic strain of porcine reproductive and respiratory syndrome virus - (Abstract Only)

Miller, L.C., Fleming, D., Arbogast, A., Bayles, D.O., Guo, B., Lager, K.M., Henningson, J.N., Schlink, S.N., Yang, H., Faaberg, K.S., Kehrli, Jr., M.E. 2012. Swine tracheobronchial lymph node mRNA responses in swine infected with a highly pathogenic strain of porcine reproductive and respiratory syndrome virus. 2012 International PRRS Symposium. p. 96.

Antibody repertoire development in fetal and neonatal piglets. XVI. Influenza stimulates adaptive immunity, class switch and diversification of the IgG repertoire encoded by downstream C-gamma genes - (Peer Reviewed Journal)

Butler, J.E., Sun, X., Wertz, N., Vincent, A.L., Zanella, E.L., Lager, K.M. 2013. Antibody repertoire development in fetal and neonatal piglets. XVI. Influenza stimulates adaptive immunity, class switch and diversification of the IgG repertoire encoded by downstream C-gamma genes. Immunology. 138(2):134-144.

Frequency of genomic reassortment of influenza A virus in North American swine, 1998-2011 - (Peer Reviewed Journal)

Nelson, M.I., Detmer, S.E., Wentworth, D.E., Tan, Y., Schwartzbard, A., Halpin, R.A., Stockwell, T.B., Lin, X., Vincent, A.L., Gramer, M.R., Holmes, E.C. 2012. Genomic reassortment of influenza A virus in North American swine, 1998-2011. Journal of General Virology. 93(Pt 12):2584-2589.

Infection of United States swine with a Chinese highly pathogenic strain of porcine reproductive and respiratory syndrome virus - (Peer Reviewed Journal)

Guo, B., Lager, K.M., Henningson, J.N., Miller, L.C., Schlink, S.N., Kappes, M.A., Kehrli, Jr., M.E., Brockmeier, S.L., Nicholson, T.L., Yang, H., Faaberg, K.S. 2013. Experimental infection of United States swine with a Chinese highly pathogenic strain of porcine reproductive and respiratory syndrome virus. Virology. 435(2):372-384.

Diversity of viruses detected by deep sequencing in pigs from a common background - (Peer Reviewed Journal)

Lager, K.M., Ng, T.F., Bayles, D.O., Alt, D.P., Delwart, E.L., Cheung, A.K. 2012. Diversity of viruses detected by deep sequencing in pigs from a common background. Journal of Veterinary Diagnostic Investigation. 24(6):1177-1179.

Analysis of the swine tracheobronchial lymphnode transcriptomic response to infection with a Chinese highly pathogenic strain of porcine reproductive and respiratory syndrome virus - (Peer Reviewed Journal)

Miller, L.C., Fleming, D., Arbogast, A., Bayles, D.O., Guo, B., Lager, K.M., Henningson, J.N., Schlink, S.N., Yang, H.-C., Faaberg, K.S., Kehrli, Jr., M.E. 2012. Analysis of the swine tracheobronchial lymph node transcriptomic response to infection with a Chinese highly pathogenic strain of porcine reproductive and respiratory syndrome virus. BioMed Central (BMC) Veterinary Research. 8(1):208. Available: http://www.biomedcentral.com/1746-6148/8/208.

Replicative intermediates of porcine circovirus in animal tissue cultured cells or in bacteria undergoing copy-release replication - (Peer Reviewed Journal)

Cheung, A.K. 2012. Replicative intermediates of porcine circovirus in animal tissue cultured cells or in bacteria undergoing copy-release replication. Virology. 434(1):38-42.

Frequent global transmission of H1N1pdm09 influenza viruses from humans to swine, 2009-2011 - (Peer Reviewed Journal)

Nelson, M.I., Gramer, M.R., Vincent, A.L., Holmes, E.C. 2012. Global transmission of influenza viruses from humans to swine. Journal of General Virology. 93(10):2195-2203.

Flu virus continues to evolve in swine - (Trade Journal)

Gauger, P.C., Zhang, J., Vincent, A.L. 2012. Flu virus continues to evolve in swine. National Hog Farmer. Available: http://nationalhogfarmer.com/health/flu-virus-continues-evolve-swine.

Development of antinuclear antibodies and a genetic linkage in pigs infected with porcine circovirus type 2 - (Abstract Only)

Cheung, A.K., Kehrli, Jr., M.E., Lager, K.M., Gauger, P.C., Rohrer, G.A., Michael, D.D., Miller, L.C., Vincent, A.L., Braucher, D.R. 2012. Development of antinuclear antibodies and a genetic linkage in pigs infected with porcine circovirus type 2 [abstract]. IXth International Congress of Veterinary Virology. p. 189-190.

Antibody repertoire development in fetal and neonatal piglets. XXII. Lambda rearrangement precedes kappa rearrangement during B-cell lymphogenesis in swine - (Peer Reviewed Journal)

Sun, X., Wertz, N., Lager, K., Sinkora, M., Stepanova, K., Tobin, Butler, J.E. 2012. Antibody repertoire development in fetal and neonatal piglets. XXII. Lambda rearrangement precedes kappa rearrangement during B-cell lymphogenesis in swine. Immunology. 137(2):149-159.

Evolution of H3N2v viruses in North American swine and humans, 2009-2011 - (Peer Reviewed Journal)

Nelson, M.I., Vincent, A.L., Kitikoon, P., Holmes, E.C., Gramer, M.R. 2012. The evolution of novel reassortant A/H3N2 influenza viruses in North American swine and humans, 2009-2011. Journal of Virology. 86(16):8872-8878.

Chimeric viruses containing the N-terminal ectodomains of GP5 and M proteins of porcine reproductive and respiratory syndrome do not change the cellular tropism of equine arteritis virus - (Peer Reviewed Journal)

Lu, Z., Zhang, J., Huang, C.M., Go, Y.Y., Faaberg, K.S., Rowland, R.R., Timoney, P.J., Balasuriya, U.B. 2012. Chimeric viruses containing the N-terminal ectodomains of GP5 and M proteins of porcine reproductive and respiratory syndrome virus do not change the cellular tropism of equine arteritis virus. Virology. 432(1):99-109.

Induction of type I interferons by a novel porcine reproductive and respiratory syndrome virus isolate - (Peer Reviewed Journal)

Nan, Y., Wang, R., Shen, M., Faaberg, K.S., Samal, S.K., Zhang, Y.J. 2012. Induction of type I interferons by a novel porcine reproductive and respiratory syndrome virus isolate. Virology. 432(2):261-270.

Simultaneous infection of pigs and people with triple reassortant swine influenza virus H1N1 at a U.S. county fair     - (Peer Reviewed Journal)

Killian, M.L., Swenson, S.L., Vincent, A.L., Landgraf, J.G., Shu, B., Lindstrom, S., Xu, X., Klimov, A., Zhang, Y., Bowman, A.S. 2013. Simultaneous infection of pigs and people with triple-reassortant swine influenza virus H1N1 at a U.S. county fair. Zoonoses and Public Health. 60(3):196-201.

Antibody repertoire development in fetal and neonatal piglets. XXIII: fetal piglets infected with a vaccine strain of PRRS virus display the same immune dysregulation seen in isolator piglets - (Peer Reviewed Journal)

Sun, X.Z., Wertz, N., Lager, K.M., Tobin, G., Butler, J.E. 2012. Antibody repertoire development in fetal and neonatal piglets. XXIII: fetal piglets infected with a vaccine strain of PRRS virus display the same immune dysregulation seen in isolator piglets. Vaccine. 30(24):3646-3652.

Virion packaging of multiple cleavage isoforms of porcine reproductive and respiratory syndrome virus nonstructural protein 2 - (Abstract Only)

Kappes, M.A., Faaberg, K.S. 2012. Virion packaging of multiple cleavage isoforms of porcine reproductive and respiratory syndrome virus nonstructural protein 2 [abstract]. American Society for Virology 31st Annual Meeting. p. 161-162.

Pathogenicity of swine influenza viruses possessing an avian or swine-origin PB2 polymerase gene evaluated in mouse and pig models - (Peer Reviewed Journal)

Ma, W., Lager, K.M., Li, X., Janke, B.H., Mosier, D.A., Painter, L.E., Ulery, E.S., Ma, J., Lekcharoensuk, P., Webby, R.J., Richt, J.A. 2011. Pathogenicity of swine influenza viruses possessing an avian or swine-origin PB2 polymerase gene evaluated in mouse and pig models. Virology. 410(1):1-6.