Location: Livestock Issues Research
Project Number: 6208-32000-007-05
Start Date: Apr 01, 2010
End Date: Mar 31, 2015
Twenty-four recently weaned calves weighing approximately 500 pounds will be transported to our research facility. Upon arrival, all calves will be weighed and placed into one of three treatment groups in a manner that balances the body weights across treatments. The three treatment groups will consist of: 1) Control group, n = 8 calves, fed a standard receiving diet; 2) Live Yeast group, n = 8 calves, fed the Control diet containing live yeast; and 3) Yeast Cell Wall group, n = 8 calves, fed Control diet containing a yeast cell wall product. Calves will be fed their respective diets for 21 days. On day 22, all calves will be fitted with indwelling jugular catheters and probes to measure rectal temperature. On day 23, all calves will be subjected to an immune challenge to determine their innate immune response. Serum samples collected during the study will be analyzed within the Livestock Issues Research Unit for hormones and proinflammatory cytokines associated with the stress and immune response. Additionally, performance data will be collected to determine if the yeast supplements alter performance prior to and after the immune challenge.