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United States Department of Agriculture

Agricultural Research Service

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Research Project: Further Studies of Spontaneous Avian Leukokis-Like Tumors in Chickens

Location: Avian Disease and Oncology Laboratory

Project Number: 3635-32000-016-05
Project Type: Specific Cooperative Agreement

Start Date: Apr 17, 2012
End Date: Aug 14, 2014

Objective:
Determine the characteristics of spontaneous avian leukosis-like tumors in chickens.

Approach:
A pyrosequencing assay will be used to assess the TVB genotypes of commercial broiler breeder chickens (200 chickens) in order to determine the genetic susceptibility of the commercial chickens to ALV-E. Using gene expression analysis by microarrays, and by using DNA Southern blotting and hybridization, the tumors induced in chickens (20 samples) will be characterized and the oncogene involved will be determined.

Last Modified: 7/22/2014
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