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United States Department of Agriculture

Agricultural Research Service

Research Project: Determination of Correlation Between Serum Antibodies and Protection Afforded by Vaccination Against Bvdv Project Number: 5030-32000-106-11
Project Type: Nonfunded Cooperative Agreement

Start Date: Feb 01, 2012
End Date: Jan 31, 2013

Objective:
Determine if there is a correlation between bovine viral diarrhea virus (BVDV) neutralizing antibodies and protection against BVDV exposure in vaccinated calves.

Approach:
Angus beef calves raised under production conditions will be vaccinated with a commercial bovine viral diarrhea virus (BVDV) vaccine. Calves with low, mid range, or high levels of serum neutralizing antibodies following vaccination will be selected. Selected calves will be transferred to the National Animal Disease Center and challenged with a high virulence BVDV. This will be done to determine the level of neutralizing antibodies required for protection.

Last Modified: 10/30/2014
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