Location: Molecular Plant Pathology
Project Number: 1245-22000-274-00
Start Date: Mar 16, 2012
End Date: Mar 15, 2017
In Objective 1, we will 1) characterize the genome expression strategy of Maize rayado fino virus and develop into a gene expression tool for maize, and 2) develop novel plant virus-based expression vectors for plants using organelle targeting sequences derived from viroids and viruses. In Objective 2, we will 1) determine the role of membrane-associated, phospholipid-signaling phosphorylation pathways in virus and viroid infection, and 2) evaluate genes with potential for conferring resistance to bacterial pathogens in plants. In Objective 3, we will 1) express novel functional proteins in plants for treatment and control of animal diseases, and 2) develop multi-component vaccines and diagnostic reagents by expression of diverse molecules on the surface of a plant virus-like particle.