Start Date: Sep 01, 2012
End Date: Jun 30, 2013
Five to six week old colostrum deprived calves will be exposed to one of seven field strains of bovine corona virus. Clinical signs will be monitored including basal temperature, circulating white blood cells and shedding of virus in nasal and rectal swabs. At six days calves will be necropsied and their lungs scored for lesions.