Location: Animal Diseases Research
Project Number: 5348-32000-034-07
Start Date: Oct 01, 2013
End Date: Sep 30, 2018
The approach to antigen discovery is twofold. One approach, in collaboration with colleagues at the University of Maryland is comparative, global in silico genomic analysis of T. equi strains and in vivo analysis of the ability of T. parva antigens to induce cytotoxic and helper lymphocyte responses. Finally, a modified live vector that doesn’t cause disease, but induces appropriate immune responses will be utilized to deliver appropriate T. parva antigens.