Location: Food Components and Health Laboratory
Project Number: 1235-51530-010-00
Start Date: Jan 23, 2014
End Date: Jan 22, 2019
Diet is a modifiable lifestyle factor that can influence the multitude of chronic diseases faced by an increasing proportion of the U.S. population, including type 2 diabetes, hypertension, vascular dysfunction, cardiovascular disease, cancer, and arthritis. Moreover, the widespread global prevalence of these diseases threatens the quality of life and places additional stresses on an already overburdened health care system. This project, through highly controlled human feeding studies, will target specific factors which influence risk for and development of chronic disease. First, research will be conducted to improve accuracy of the energy value of foods, which can impact weight gain, a risk factor for chronic disease. Second, research will be conducted to investigate dietary factors that can influence cardiometabolic profile, i.e. risk for cardiovascular disease, stroke, or diabetes. Third, we will study how diet influences voluntary food intake, again impacting weight gain, a risk factor for chronic disease. The outcomes of this research will provide a better understanding of 1) the energy content of specific foods in the context of a mixed diet, and the absorption, metabolism and impact on biomarkers for health promotion of these foods or their components, 2) dietary and lifestyle influences on diabetes and cardiovascular disease risk, and 3) the extent to which the day-to-day variation in daily voluntary food intake is related to diet composition. This research will fill knowledge gaps in the metabolism of macro and micro food components related to the development and management of obesity and chronic diseases, and provide a scientific basis for dietary recommendations and nutrition policy.