Research Project: Develop Technologies for Production of Platform Chemicals and Advanced Biofuels from Lignocellulosic Feedstocks

Location: Bioenergy Research

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Development and characterization of Saccharomyces cerevisiae strains genetically modified to over-express the pentose phosphate pathway regulating transcription factor STB5 in the presence of xylose - (Peer Reviewed Journal)
Hohenschuh, W., Hector, R.E., Mertens, J.A., Murthy, G.S. 2020. Development and characterization of Saccharomyces cerevisiae strains genetically modified to over-express the pentose phosphate pathway regulating transcription factor STB5 in the presence of xylose. Systems Microbiology and Biomanufacturing. 1: 42-57. https://doi.org/10.1007/s43393-020-00002-y.

Using high throughput data and dynamic flux balance modeling techniques to identify points of constraint in xylose utilization in Saccharomyces cerevisiae - (Peer Reviewed Journal)
Hohenschuh, W., Hector, R.E., Chaplen, F., Murthy, G.S. 2021. Using high throughput data and dynamic flux balance modeling techniques to identify points of constraint in xylose utilization in Saccharomyces cerevisiae. Systems Microbiology and Biomanufacturing. 1: 58-75. https://doi.org/10.1007/s43393-020-00003-x.

Efficient bioconversion of waste bread into 2-keto-D-gluconic acid by Pseudomonas reptilivora NRRL B-6 - (Peer Reviewed Journal)
Yegin, S., Saha, B.C., Kennedy, G.J., Berhow, M.A., Vermillion, K. 2020. Efficient bioconversion of waste bread into 2-keto-D-gluconic acid by Pseudomonas reptilivora NRRL B-6. Biomass Conversion and Biorefinery. 10(2):545-553. https://doi.org/10.1007/s13399-020-00656-7.

Production of acetone-butanol-ethanol (ABE) from concentrated yellow top presscake using Clostridium beijerinckii P260 - (Peer Reviewed Journal)
Qureshi, N., Saha, B.C., Liu, S., Harry O Kuru, R.E. 2019. Production of acetone-butanol-ethanol (ABE) from concentrated yellow top presscake using Clostridium beijerinckii P260. Journal of Chemical Technology & Biotechnology. 95(3):614-620. https://doi.org/10.1002/jctb.6242.

Genome expansion by allopolyploidization in the fungal strain Coniochaeta 2T2.1 and its exceptional lignocellulolytic machinery - (Peer Reviewed Journal)
Mondo, S.J., Jimenez, D.J., Hector, R.E., Lipzen, A., Yan, M., Labutti, K., Barry, K., Dirk Van Elsas, J., Grigoriev, I.V., Nichols, N.N. 2019. Genome expansion by allopolyploidization in the fungal strain Coniochaeta 2T2.1 and its exceptional lignocellulolytic machinery. Biotechnology for Biofuels. 12:229. https://doi.org/10.1186/s13068-019-1569-6.

Yellow top (Physaria fendleri) presscake: a novel substrate for butanol production and reduction in environmental pollution - (Peer Reviewed Journal)
Qureshi, N., Harry-O'Kuru, R.E., Liu, S., Saha, B. 2018. Yellow top (Physaria fendleri) presscake: a novel substrate for butanol production and reduction in environmental pollution. Biotechnology Progress. 35(3):e2767. https://doi.org/10.1002/btpr.2767.

Development and characterization of vectors for tunable expression of both xylose-regulated and constitutive gene expression in Saccharomyces yeasts - (Peer Reviewed Journal)
Hector, R.E., Mertens, J.A., Nichols, N.N. 2019. Development and characterization of vectors for tunable expression of both xylose-regulated and constitutive gene expression in Saccharomyces yeasts. New Biotechnology. 53:16-23. https://doi.org/10.1016/j.nbt.2019.06.006.

Factors affecting production of xylitol by the furfural-metabolizing fungus Coniochaeta ligniaria - (Peer Reviewed Journal)
Nichols, N.N., Hector, R.E., Frazer, S.E. 2019. Factors affecting production of xylitol by the furfural-metabolizing fungus Coniochaeta ligniaria. Current Trends in Microbiology. 12: 109-119.

Acetone-butanol-ethanol (ABE) fermentation of soluble and hydrolyzed sugars in apple pomace by Clostridium beijerinckii P260 - (Peer Reviewed Journal)
Jin, Q., Qureshi, N., Wang, H., Huang, H. 2019. Acetone-butanol-ethanol (ABE) fermentation of soluble and hydrolyzed sugars in apple pomace by Clostridium beijerinckii P260. Fuel. 244:536-544. https://doi.org/10.1016/j.fuel.2019.01.177.

Phosphate limitation alleviates the inhibitory effect of manganese on itaconic acid production by Aspergillus terreus - (Peer Reviewed Journal)
Saha, B.C., Kennedy, G.J. 2019. Phosphate limitation alleviates the inhibitory effect of manganese on itaconic acid production by Aspergillus terreus. Biocatalysis and Agricultural Biotechnology. 18:101016. https://doi.org/10.1016/j.bcab.2019.01.054.

Valorization of egg shell as a detoxifying and buffering agent for efficient polymalic acid production by Aureobasidium pullulans NRRL Y–2311–1 from barley straw hydrolysate - (Peer Reviewed Journal)
Yegin, S., Saha, B.C., Kennedy, G.J., Leathers, T. 2019. Valorization of egg shell as a detoxifying and buffering agent for efficient polymalic acid production by Aureobasidium pullulans NRRL Y–2311–1 from barley straw hydrolysate. Bioresource Technology. 278: 130-137. https://doi.org/10.1016/j.biortech.2018.12.119.

Clostridia and process engineering for energy generation - (Book / Chapter)
Mariano, A.P., Braz, D.S., Venturelli, H.C., Qureshi, N. 2020. In Vertes, A. A, Green energy to Sustainability: Strategies for global industries. John Wiley & Sons Ltd., Hoboken, NJ, USA. Clostridia and process engineering for energy generation. p.239-267.

Factors affecting production of itaconic acid from mixed sugars by Aspergillus terreus - (Peer Reviewed Journal)
Saha, B.C., Kennedy, G.J., Bowman, M.J., Qureshi, N., Dunn, R.O. 2018. Factors affecting production of itaconic acid from mixed sugars by Aspergillus terreus. Applied Biochemistry and Biotechnology. 187(2):449-460. https://doi.org/10.1007/s12010-018-2831-2

Butanol production from sweet sorghum bagasse with high solids content: Part I – comparison of liquid hot water pretreatment with dilute sulfuric acid - (Peer Reviewed Journal)
Qureshi, N., Saha, B.C., Klasson, K.T., Liu, S. 2018. Butanol production from sweet sorghum bagasse with high solids content: Part I – comparison of liquid hot water pretreatment with dilute sulfuric acid. Biotechnology Progress. 34(4):960-966. https://doi.org/10.1002/btpr.2639

High solid fed-batch butanol fermentation with simultaneous product recovery: Part II - process integration. - (Peer Reviewed Journal)
Qureshi, N., Saha, B.C., Klasson, K.T., Liu, S. 2018. High solid fed-batch butanol fermentation with simultaneous product recovery: Part II - process integration. Biotechnology Progress. 34(4):967-972. https://doi.org/10.1002/btpr.2643

Association of improved oxidative stress tolerance and alleviation of glucose repression with superior xylose-utilization capability by a natural isolate of Saccharomyces cerevisiae - (Peer Reviewed Journal)
Cheng, C., Tang, R., Xiong, L., Hector, R.E., Bai, F., Zhao, X. 2018. Association of improved oxidative stress tolerance and alleviation of glucose repression with superior xylose-utilization capability by a natural isolate of Saccharomyces cerevisiae. Biotechnology for Biofuels. 11:28. https://doi.org/10.1186/s13068-018-1018-y.

Fermentation of oat and soybean hull hydrolysates into ethanol and xylitol by recombinant industrial strains of Saccharomyces cerevisiae under diverse oxygen environments - (Peer Reviewed Journal)
Cortivo, P.R.D., Hickert, L.R.H, Hector, R., Ayub, M.A.Z. 2018. Fermentation of oat and soybean hull hydrolysates into ethanol and xylitol by recombinant industrial strains of Saccharomyces cerevisiae under diverse oxygen environments. Industrial Crops and Products. 113:10-18. doi: 10.1016/j.indcrop.2018.01.010.

Production of acetone butanol ethanol (ABE) from Physaria fendleri press cake using Clostridium beijerinckii - (Abstract Only)

Ninety six well microtiter plate as microbioreactors for production of itaconic acid by six Aspergillus terreus strains - (Peer Reviewed Journal)
Saha, B.C., Kennedy, G.J. 2017. Ninety six well microtiter plate as microbioreactors for production of itaconic acid by six Aspergillus terreus strains. Journal of Microbiological Methods. 144:53-59. doi: 10.1016/j.mimet.2017.11.002.

Recovery of butanol from Clostridium beijerinckii P260 fermentation broth by supercritical CO - (Peer Reviewed Journal)
Qureshi, N., Eller, F.J. 2018. Recovery of butanol from Clostridium beijerinckii P260 fermentation broth by supercritical CO. Journal of Chemical Technology & Biotechnology. 93(4)1206-1212. https://doi.org/10.1002/jctb.5482.

Mannose and galactose as substrates for production of itaconic acid by Aspergillus terreus - (Peer Reviewed Journal)
Saha, B.C., Kennedy, G.J. 2017. Mannose and galactose as substrates for production of itaconic acid by Aspergillus terreus. Letters in Applied Microbiology. 66(6):527-533. https://doi.org/10.1111/lam.12810.

Influence of genetic background of engineered xylose-fermenting industrial Saccharomyces cerevisiae strains for ethanol production from lignocellulosic hydrolysates - (Peer Reviewed Journal)
Dias-Lopes, D., Rosa, C.A, Hector, R.E., Dien, B.S., Mertens, J.A., Ayub, M.A.Z. 2017. Influence of genetic background of engineered xylose-fermenting industrial Saccharomyces cerevisiae strains for ethanol production from lignocellulosic hydrolysates. Journal of Industrial Microbiology and Biotechnology. 44(11):1575-1588. doi: 10.1007/s10295-017-1979-z.

Production of itaconic acid from pentose sugars by Aspergillus terreus - (Peer Reviewed Journal)
Saha, B.C., Kennedy, G.J., Qureshi, N., Bowman, M.J. 2017. Production of itaconic acid from pentose sugars by Aspergillus terreus. Biotechnology Progress. 33(4): 1059-1067. doi: 10.1002/btpr.2485.

Butanol biorefineries: Use of novel technologies to produce biofuel butanol from sweet sorghum bagasse (SSB) - (Abstract Only)
Qureshi, N., Klasson, K.T., Boddu, V.M., Liu, S., Nichols, N.N., Saha, B.C., Hughes, S.R. 2017. Butanol biorefineries: Use of novel technologies to produce biofuel butanol from sweet sorghum bagasse (SSB) [abstract]. Symposium for Biotechnology for Fuels and Chemicals, May 1-4, 2017, San Francisco, CA.

Use of liquid/supercritical CO2 extraction process for butanol recovery from fermentation broth - (Abstract Only)
Qureshi, N., Liu, S.X., Hughes, S.R., Eller, F.J. 2017. Use of liquid/supercritical CO2 extraction process for butanol recovery from fermentation broth [abstract]. 2nd Workshop on ABE Fermentation and Recovery, June 19-20, 2017, Torun, Poland.

Recovery of butanol from fermentation broth by pervaporation - (Abstract Only)
Qureshi, N., Friedl, A. 2017. Recovery of butanol from fermentation broth by pervaporation [abstract]. 2nd ABE Fermentation Workshop, Turon, Poland, 06/19-22/2017. L26.

A synthetic hybrid promoter for xylose-regulated control of gene expression in Saccharomyces yeasts - (Peer Reviewed Journal)
Hector, R.E., Mertens, J.A. 2017. A synthetic hybrid promoter for xylose-regulated control of gene expression in Saccharomyces yeasts. Molecular Biotechnology. 59(1):24-33. doi: 10.1007/s12033-016-9991-5.

Biological pretreatment of corn stover with Phlebia brevispora NRRL-13108 for enhanced enzymatic hydrolysis and efficient ethanol production - (Peer Reviewed Journal)
Saha, B.C., Kennedy, G.J., Qureshi, N., Cotta, M.A. 2017. Biological pretreatment of corn stover with Phlebia brevispora NRRL-13108 for enhanced enzymatic hydrolysis and efficient ethanol production. Biotechnology Progress. 33(2):365-374.

Production of platform chemical itaconic acid from pentose sugars - (Abstract Only)
Saha, B.C., Kennedy, G.J., Qureshi, N. 2017. Production of platform chemical itaconic acid from pentose sugars [abstract]. Meeting Abstract for Society for Micrbobiology, Biotechnology for Fuels and Chemicals, 05/01-04/2017, San Francisco, CA. Paper #M82.

Draft genome sequence of Coniochaeta ligniaria NRRL 30616, a lignocellulolytic fungus for bioabatement of inhibitors in plant biomass hydrolysates - (Peer Reviewed Journal)
Jimenez, D.J., Hector, R.E., Riley, R., Lipzen, A., Kuo, R.C., Amirebrahimi, M., Barry, K.W., Grigoriev, I.V., Dirk van Elsas, J., Nichols, N.N. 2017. Draft genome sequence of Coniochaeta ligniaria NRRL 30616, a lignocellulolytic fungus for bioabatement of inhibitors in plant biomass hydrolysates. Genome Announcements. 5(4):e01476-16. doi: 10.1128/genomeA.01476-16.

Emerging biotechnologies for production of itaconic acid and its applications as a platform chemical - (Peer Reviewed Journal)
Saha, B.C. 2017. Emerging biotechnologies for production of itaconic acid and its applications as a platform chemical. Journal of Industrial Microbiology and Biotechnology. 44(2): 303-315. doi: 10.1007/s10295-016-1878-8.

Production of xylitol from biomass using an inhibitor-tolerant fungal strain - (Abstract Only)
Nichols, N.N., Saha, B.C., Frazer, S.E. 2016. Production of xylitol from biomass using an inhibitor-tolerant fungal strain [abstract]. Frontiers in Biorefining International Conference, 11/8-11/2016, St. Simons Island, GA.

Solvent (acetone-butanol: ab) production - (Book / Chapter)
Qureshi, N. 2017. Solvent (acetone-butanol: ab) production. In: Roitberg, B. and Cotter, P. of Elsevier's Reference Module in Life Sciences. London, United Kingdom: Elsevier. p. 1-20. doi: 10.1016/B978-0-12-809633-8.13109-7.

Butanol biorefineries: simultaneous product removal & process integration for conversion of biomass & food waste to biofuel - (Abstract Only)
Qureshi, N., Huang, H., Singh, V., Liu, S., Saha, B.C., Hughes, S.R. 2016. Butanol biorefineries: simultaneous product removal & process integration for conversion of biomass & food waste to biofuel [abstract]. 14th International Conference of Genetics, Physiology, and Synthetic Biology of Solvent-and-Acid Forming Clostridia. August 28-31, 2016, Hanover, New Hampshire. Page 22. No. 017

Cellulosic butanol biofuel production from sweet sorghum bagasse (SSB): Impact of hot water pretreatment and solid loadings on fermentation employing Clostridium beijerinckii P260 - (Peer Reviewed Journal)
Qureshi, N., Liu, S., Hughes, S., Palmquist, D., Dien, B., Saha, B. 2016. Cellulosic butanol (ABE) biofuel production from sweet sorghum bagasse (SSB): Impact of hot water pretreatment and solid loadings on fermentation employing Clostridium beijerinckii P260. BioEnergy Research. 9(4):1167-1179. doi: 10.1007/s12155-016-9761-z.

Biological pretreatment of corn stover with white-rot fungus for enzymatic hydrolysis and bioethanol production - (Abstract Only)
Saha, B.C., Kennedy, G.J., Qureshi, N., Cotta, M.A. 2016. Biological pretreatment of corn stover with white-rot fungus for enzymatic hydrolysis and bioethanol production [abstract]. Biotechnology for Fuels and Chemicals. 2-7

Production of xylitol by a Coniochaeta ligniaria strain tolerant of inhibitors and defective in xylose metabolism - (Peer Reviewed Journal)
Nichols, N.N., Saha, B.C. 2016. Production of xylitol by a Coniochaeta ligniaria strain tolerant of inhibitors and defective in growth on xylose. Biotechnology Progress. 32(3):606-612. doi: 10.1002/btpr.2259.

Enhancing ethanol production from cellulosic sugars using Scheffersomyces (Pichia) stipitis - (Peer Reviewed Journal)
Okonkwo, C.C., Azam, M.M., Ezeji, T.C., Qureshi, N. 2016. Enhancing ethanol production from cellulosic sugars using Scheffersomyces (Pichia) stipitis. Bioprocess and Biosystems Engineering. 39(7):1023-1032. doi: 10.1007/s00449-016-1580-2.

Biological pretreatment of corn stover with white-rot fungus for improved enzymatic hydrolysis - (Peer Reviewed Journal)
Saha, B.C., Qureshi, N., Kennedy, G.J., Cotta, M.A. 2016. Biological pretreatment of corn stover with white-rot fungus for improved enzymatic hydrolysis. International Biodeterioration and Biodegradation. 109:29-35. doi: 10.1016/j.ibiod.2015.12.020.

Butanol production from food waste: a novel process for producing sustainable energy and reducing environmental pollution - (Peer Reviewed Journal)
Huang, H., Singh, V., Qureshi, N. 2015. Butanol production from food waste: a novel process for producing sustainable energy and reducing environmental pollution. Biotechnology for Biofuels. 8:147. doi: 10.1186/s13068-015-0332-x.

Butanol production by fermentation: efficient bioreactors - (Book / Chapter)
Mariano, A.P., Ezeji, T.C., Qureshi, N. 2015. Butanol production by fermentation: Efficient bioreactors. In: Snyder, S.W., editor. Commercializing Biobased Products: Opportunities, Challenges, Benefits, and Risks, 2015. RSC Publishing, Cambridge, United Kingdom. p. 48-70. doi: 10.1039/9781782622444-00048.

Cellulosic Substrates and Challenges Ahead - (Abstract Only)
Qureshi, N. 2015. Cellulosic Substrates and Challenges Ahead [abstract].

Enhancement of xylose utilization from corn stover by a recombinant bacterium for ethanol production - (Abstract Only)
Saha, B.C., Qureshi, N., Kennedy, G.J., Cotta, M.A. 2015. Enhancement of xylose utilization from corn stover by a recombinant bacterium for ethanol production [abstract]. American Society for Microbiology. 190:182-188

Enhancement of xylose utilization from corn stover by a recombinant bacterium for ethanol production - (Peer Reviewed Journal)
Saha, B.C., Qureshi, N., Kennedy, G.J., Cotta, M.A. 2015. Enhancement of xylose utilization from corn stover by a recombinant Escherichia coli strain for ethanol production. Bioresource Technology. 190:182-188.

Ethanol production from food waste at high solid contents with vacuum recovery technology - (Peer Reviewed Journal)
Huang, H., Qureshi, N., Chen, M., Liu, W., Singh, V. 2015. Ethanol production from food waste at high solid contents with vacuum recovery technology. Journal of Agricultural and Food Chemistry. 63:2760-2766.

A dynamic flux balance model and bottleneck identification of glucose, xylose, xylulose co-fermentation in Saccharomyces cerevisiae - (Peer Reviewed Journal)
Hohenschuh, W., Hector, R.E., Murthy, G.S. 2015. A dynamic flux balance model and bottleneck identification of glucose, xylose, xylulose co-fermentation in Saccharomyces cerevisiae. Bioresource Technology. 188:153-160.

Genetically engineered Escherichia coli FBR5 to use cellulosic sugars: Production of ethanol from corn fiber hydrolyzate employing commercial nutrient medium - (Peer Reviewed Journal)
Qureshi, N., Dien, B.S., Saha, B.C., Iten, L., Liu, S., Hughes, S.R. 2015. Genetically engineered Escherichia coli FBR5 to use cellulosic sugars: Production of ethanol from corn fiber hydrolyzate employing commercial nutrient medium. European Chemical Bulletin. 4(3):130-134. https://doi.org/10.17628/ecb.2015.4.130-134