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United States Department of Agriculture

Agricultural Research Service

Related Topics

Research Project: Milk Vs. Calcium Citrate and Vitamin D for Bone Health in Postmenopausal Women

Location: Obesity and Metabolism Research Unit

Project Number: 5306-51000-004-03
Project Type: Trust

Start Date: Oct 01, 2010
End Date: Sep 30, 2015

Objective:
Objective: 1) Determine bone density; 2) determine bone metabolism; 3) evaluate calcium losses from the skeleton.

Approach:
Conduct a human study using 41Ca isotope tracer to quantify calcium losses directly from the skeleton in postmenopausal women. Sixteen healthy postmenopausal women will be enrolled and labeled with 41Ca tracer. Following tracer equilibration (~6mo.)women will be randomly assigned to 1 of 2 treatments: 1) 3-4 servings/d milk or 2) equivalent calcium citrate supplementation. Following first intervention women will cross-over to the other intervention. Urine and sera samples will be collected and analyzed for 41Ca excretion, bone metabolism markers, PTH and 25-(OH)vitamin D. Documents Trust with Dairy Research Institute. Log 41795.

Last Modified: 9/2/2014
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