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United States Department of Agriculture

Agricultural Research Service

Related Topics

Research Project: Phenotypic and Genomic Database Creation for Cattle in Industry Populations

Location: Genetics, Breeding, & Animal Health

Project Number: 3040-31320-012-02
Project Type: Specific Cooperative Agreement

Start Date: Jul 01, 2012
End Date: Jun 30, 2017

Objective:
Create and maintain a phenotypic and genomic database for cattle in industry populations that will be used for the validation of DNA associations found in the research population at USMARC. Characterize said populations and analyze data as appropriate for validation.

Approach:
Collaborators with USMARC scientists are developing external validation populations comprised of industry animals. Data from these populations are collected by collaborators and by breed associations. These data will be transferred to Cornell’s Animal Science department for quality assessment, summary analysis, storage and retrieval. DNA samples for these animals will be analyzed for SNP genotypes from the standard 50K and HD Illumina SNP assays. Associations between SNP genotypes and SNP effects discovered in the USMARC discovery population will be made to create Molecular Breeding Value (MBV) estimates for individual animals. Data will be analyzed for the association of the MBV’s with Expected Progeny Differences (EPD) or phenotypic information.

Last Modified: 12/20/2014
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