Project Number: 1245-31000-104-06
Start Date: Apr 01, 2012
End Date: Mar 30, 2015
Software will be developed and adapted for analyzing 1) the extent and pattern of segmental duplication in the cattle genome assembly, and 2) the whole genome structure variation data being generated by the CNV project sponsored by USDA, including use of array comparative genomic hybridization (array CGH) information, survey of normal baselines of CNV and identification of positional candidate genes. Emphasis should be given to problems related to the bovine genome sequencing and hapmap projects, as BFGL is closely involved in those efforts, although development of tools with wide utility is a priority. Tools will be developed or adapted to reliably identify and characterize CNV across and within breeds or strains of a species.