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United States Department of Agriculture

Agricultural Research Service

Title: Influence of Marek's Disease Vaccines on the Response of Commercial Broiler Breeder Chickens to Infection with Subgroup J Avian Leukosis Virus

Author
item Fadly, Aly

Submitted to: Western Poultry Disease Conference
Publication Type: Abstract Only
Publication Acceptance Date: May 1, 2002
Publication Date: N/A

Technical Abstract: Chickens of three commercial broiler breeder lines and two experimental lines were inoculated with strain ADOL-Hc1 of subgroup J avian leukosis virus (ALV-J) at hatch; chickens were also vaccinated with serotype 1, 2 or 3 Marek's disease (MD) vaccines. Vaccinated and unvaccinated, ALV-J-infected chickens were monitored for ALV-J induced infection and tumors through 32 weeks of age. At 32 weeks of age, the incidence of ALV-J viremia in chickens vaccinated with herpesvirus of turkeys (HVT), a serotype 3 MD vaccine virus varied from 0% to 100%, depending on line of chickens. Whereas, the incidence of ALV-J viremia in chickens of one commercial line was significantly higher in groups vaccinated with a serotype 1 MD vaccine virus than those vaccinated with HVT or bivalent vaccines containing serotype 2 MD virus. Also, the incidence of ALV-J tumors in chickens of 1 of 3 commercial lines tested, was significantly higher in groups vaccinated with serotype 1 MD vaccine virus than in unvaccinated groups or groups vaccinated with HVT or bivalent vaccines. Results suggest that MDV vaccines may influence ALV-J infection and tumors, but only in certain lines of chickens.

Last Modified: 8/22/2014
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