Submitted to: American Veterinary Medical Association Abstract
Publication Type: Abstract Only
Publication Acceptance Date: May 1, 2002
Publication Date: May 1, 2003
Citation: OKARMURA, M., LILLEHOJ, H.S., BABU, U.S., RAYBOURNE, R.B., HECKERT, R.A. CELLULAR IMMUNE RESPONSES VACCINATED WITH SALMONELLA ENTERITIDIS BACTERIN. AMERICAN VETERINARY MEDICAL ASSOCIATION ABSTRACT. 2003.
The effects of Salmonella enteritidis vaccination on the host cellular immune response was evaluated. Chickens were vaccinated subcutaneously with killed S. enteritidis vaccine at the ages of 3 and 5 weeks. After vaccination, serum samples were collected for 3 weeks for the evaluation of IFN- and IL-2 levels. The IFN- level was significantly (p<0.05) higher in the vaccine group at 7, 11, 14, and 21 days post vaccination (dpv) whereas the IL-2 level was higher at 14, 18, and 21 dpv. Therefore, killed S. enteritidis vaccine induce important chicken cytokines which are involved in the elimination of the intracellular Salmonella.