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United States Department of Agriculture

Agricultural Research Service

Title: Case Study: Risk Analysis of Fumonisin in "fao Risk Analysis Manual"

Authors
item Riley, Ronald
item Miller, J. David - CARLETON UNIV.OTT/ON/CAN.

Submitted to: FAO Technical Reports
Publication Type: Book / Chapter
Publication Acceptance Date: August 15, 2003
Publication Date: November 1, 2003
Citation: FAO: Food Safety - Risk Analysis, a manual published by the United Nations Food & Agriculture Organization, ILSI, and the Industry Council for Development.

Interpretive Summary: This document is written as a Case Study for the "FAO Risk Analysis Manual" developed by the Industry Council for Development in close association with the Food and Agricultural Organization for use in training programs in the field of food safety and nutrition. The risk analysis process includes risk assessment, risk management, risk communication and risk perception. The four components of the risk analysis framework are interdependent and none can occur independent of the other three. Thus, the interaction between the components is essential if the risk analysis is to be effective. The purpose of this case study is to show how the risk assessment component evolves for a natural food contaminant using the mycotoxin fumonisin B1 as an example. In theory, the risk assessment component is comprised of four discrete parts: hazard identification; hazard characterization, exposure assessment; and risk characterization. In reality, hazard identification and characterization (establishing the dose response relationships) and exposure assessment all occur concurrently. The emphasis is on the risk assessment component of the fumonisin risk analysis, however, the points in the evolution of the risk assessment where interaction between risk managers and stakeholders were critical in ensuring its scientific quality are also described in detail. The problems that are unique to the risk analysis of natural contaminants in foods are addressed and a "Decision Tree" that takes a DNA reactive and non-DNA reactive food borne mycotoxin through the risk assessment evaluation process is included as a training tool.

Technical Abstract: This document is written as a Case Study for the "FAO Risk Analysis Manual" developed by the Industry Council for Development in close association with the Food and Agricultural Organization for use in training programs in the field of food safety and nutrition. The risk analysis process includes risk assessment, risk management, risk communication and risk perception. The four components of the risk analysis framework are interdependent and none can occur independent of the other three. Thus, the interaction between the components is essential if the risk analysis is to be effective. The purpose of this case study is to show how the risk assessment component evolves for a natural food contaminant using the mycotoxin fumonisin B1 as an example. In theory, the risk assessment component is comprised of four discrete parts: hazard identification; hazard characterization, exposure assessment; and risk characterization. In reality, hazard identification and characterization (establishing the dose response relationships) and exposure assessment all occur concurrently. The emphasis is on the risk assessment component of the fumonisin risk analysis, however, the points in the evolution of the risk assessment where interaction between risk managers and stakeholders were critical in ensuring its scientific quality are also described in detail. The problems that are unique to the risk analysis of natural contaminants in foods are addressed and a "Decision Tree" that takes a DNA reactive and non-DNA reactive food borne mycotoxin through the risk assessment evaluation process is included as a training tool. This document is written as a Case Study for the "FAO Risk Analysis Manual" developed by the Industry Council for Development in close association with the Food and Agricultural Organization for use in training programs in the field of food safety and nutrition. The risk analysis process includes risk assessment, risk management, risk communication and risk perception. The four components of the risk analysis framework are interdependent and none can occur independent of the other three. Thus, the interaction between the components is essential if the risk analysis is to be effective. The purpose of this case study is to show how the risk assessment component evolves for a natural food contaminant using the mycotoxin fumonisin B1 as an example. In theory, the risk assessment component is comprised of four discrete parts: hazard identification; hazard characterization, exposure assessment; and risk characterization. In reality, hazard identification and characterization (establishing the dose response relationships) and exposure assessment all occur concurrently. The emphasis is on the risk assessment component of the fumonisin risk analysis, however, the points in the evolution of the risk assessment where interaction between risk managers and stakeholders were critical in ensuring its scientific quality are also described in detail. The problems that are unique to the risk analysis of natural contaminants in foods are addressed and a "Decision Tree" that takes a DNA reactive and non-DNA reactive food borne mycotoxin through the risk assessment evaluation process is included as a training tool.

Last Modified: 11/26/2014
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