ARS | Publication request: REDUCTION OF CAMPYLOBACTER AND SALMONELLA IN PIGS TREATED WITH A SELECT NITROCOMPOUND

Submitted to: International Symposium on the Epidemiology and Control of Foodborne Pathogens in Pork
Publication Type: Proceedings
Publication Acceptance Date: September 9, 2003
Publication Date: October 1, 2003
Citation: Jung, Y., Anderson, R.C., Genovese, K.J., Edrington, T.S., Callaway, T.R., Byrd II, J.A., Bischoff, K.M., Harvey, R.B., McReynolds, J., Nisbet, D.J. 2003. Reduction of Campylobacter and Salmonella in pigs treated with a select nitrocompound. Proceedings of 5th International Symposium on the Epidemiology and Control of Foodborne Pathogens in Pork (SafePork '03). p. 205-207.

Technical Abstract: The aim of this study was to test the effectiveness of administering a select nitrocompound (S-NO) on reducing naturally colonized Campylobacter and experimentally infected Salmonella in the weaned pig gut. Pigs were divided into four groups; control (0 g S-NO/pig), 1X (0.2 g S-NO/pig), 5X (1 g S-NO/pig), and 10X (2 g S-NO/pig). Treatments were administered via oral gavage 24 h before sacrifice. Mean +/- SD populations (log10 cfu/g) of Campylobacter in the cecum were reduced (P < 0.05) in pigs receiving the 10 X dose when compared with untreated controls (1.64 +/- 1.30 vs 5.31 +/- 0.58, respectively). Campylobacter concentrations in rectal contents from pigs administered the 5X dose were reduced (P < 0.05) compared to control (2.65 +/- 2.86 vs 5.90 +/- 0.94, respectively). Rectal Salmonella concentrations were reduced (P < 0.05) in all of the S-NO-treated groups. No adverse effects of S-NO on pig health were observed. These results demonstrate that S-NO may have potential as a preharvest intervention strategy that can reduce colonization by Campylobacter and Salmonella in pigs.