Submitted to: Southern Poultry Science Society Meeting Abstracts
Publication Type: Proceedings
Publication Acceptance Date: October 30, 2004
Publication Date: January 15, 2005
Citation: Collier, S.D., Pharr, G.T., Branton, S.L., Evans, J.D. 2005. Effects of mg vaccinations on b and t-cell populations in layer chickens. Southern Poultry Science Society Meeting. Abstract 206. p. 49. Technical Abstract: Mycoplasma gallisepticum (MG) results in economic losses in chickens via morbidity and mortality. The resulting chronic respiratory infection reduces egg production and contributes to condemnation of meat at poultry processing plants. Attempts to control MG infections have primarily involved prophylaxis using live vaccines of attenuated strains. However, the exact mechanisms by which the available MG vaccines confer protection in layer chickens, is currently unknown. In the present study, flow cytometry was used to examine the humoral and cellular immune responses of chickens inoculated with 6/85 at 60 wk of age, then challenged with F strain at 62 wk of age. There were significant changes in the percentage of Bu-1+ and CD4+ peripheral blood lymphocytes isolated from vaccinated birds at 66 wk of age in comparison to control birds. The results of this study suggest that humoral and cellular immunity may play a role in the protective immune response induced by MG vaccines.