Technical Abstract: Americans pay a staggering $117 billion annually in health care costs associated with obesity-related disease, resulting in close to 300,000 deaths annually. In 2000, the World Health Organization found 300 million people around the globe were obese. The “globesity” epidemic is commonly attributed to increased dietary intake of high-energy, high fat foods and reduced physical activity. While caloric imbalance is the major contributing factor, low consumption of healthy foods such as fruits and vegetables and other foods that are high in dietary fibers, antioxidants, micronutrients, essential fatty acids, and proteins have been found to be associated with increased incidence of obesity. The development of new foods and food ingredients that are high in these components will provide food manufacturers and consumers with alternative food choices to help prevent obesity. New technologies are needed to develop specific obesity prevention foods that not only promote health, but are also convenient and easy to consume. Furthermore, human clinical trials are needed to scientifically validate the ability of these new foods to prevent obesity.