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United States Department of Agriculture

Agricultural Research Service

Title: Method of Protecting Fish Against Columnaris Disease with Modified Live Flavobacterium Columnare

Authors
item Shoemaker, Craig
item Klesius, Phillip
item Evans, Joyce

Submitted to: Invention Report
Publication Type: Patent Application
Publication Acceptance Date: January 31, 2006
Publication Date: January 31, 2006
Citation: Shoemaker, C.A., Klesius, P.H., Evans, J.J. 2006. Method of protecting fish against columnaris disease with modified live Flavobacterium columnare. U.S. Patent US 6,991,793 B2.

Technical Abstract: Safe and effective live vaccines against Flavobacterium columnare of fish were created through the induction of rifampicin resistance in a native Flavobacterium columnare isolate; these including rifampicin-resistant mutants NRRL B-30303 and B30304. Single immersion exposure of fish stimulated acquired immunity against virulent F. columnare infection.

Last Modified: 12/22/2014
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