Technical Abstract: This study was conducted to evaluate the effects of long-term intensive swine effluent application on nutrient dynamics and chemical changes of an alkaline Okolona silty clay, an acidic Vaiden silty clay and a Brooksville silty clay loam. Three soils receiving swine effluent are representative of the Blackland Prairie major land resource area initially testing very low (Vaiden) to low (Okolona and Brooksville) in Phosphorus (P). Swine effluent has been applied to the soils under established summer forage grasses using a center-pivot or traveling gun irrigation systems at the rate of approximately 10-15 cm ha-1yr-1 since 1990. In 2006, soil samples were taken from swine effluent treated and non-treated soils, divided into the depth of 0-15, 15-30, 30-60, and 60-90 cm, air dried, ground to pass 2 mm sieve and analyzed for chemical properties. Long-term swine effluent applications resulted in increasing soil pH, electrical conductivity and soil total C in all soils. Chemical extractable soil P was much lower in the alkaline Okolona soil (60 mg kg-1) than the acidic Vaiden soil (119 mg kg-1). The potential leaching of soluble salts and NO3 in the alkaline Okolona soil was greater than in the acidic Vaiden soil possibly due to cracking nature of the alkaline Okolona soil. Water soluble P, and soil Cu and Zn concentrations were lower in the alkaline Okolona soil than in the Vaiden and Brooksville soils. Low nutrient concentrations, especially water soluble P, at the surface alkaline Okolona could be related to the presence of free CaCO3 and precipitation of soluble P with Ca which may prolong the capacity of this soil in receiving swine effluent particularly if threshold water soluble P is used as part of swine effluent management program.