METABOLIC VARIABLES AFFECTING THE EFFICACY, SAFETY, AND FATE OF AGRICULTURAL CHEMICALS
Location: Animal Metabolism-Agricultural Chemicals Research
Title: Fate of chlorate salts excreted from animals.
Submitted to: American Chemical Society Abstracts
Publication Type: Abstract Only
Publication Acceptance Date: December 16, 2006
Publication Date: March 24, 2007
Citation: Smith, D.J., Oliver, C.E., Hakk, H., Anderson, R.C., Larsen, G.L. 2007. Fate of chlorate salts excreted from animals. Meeting Abstract. American Chemical Society Abstracts, March 25-29, 2007, Chicago, IL.
A new pre-harvest food safety technology, based upon the oral administration of chlorate to food animals, selectively eliminates gram-negative pathogens such as E. coli O157:H7 and Salmonella species in economically important livestock species. Residue trials have demonstrated that chlorate salts are rapidly and extensively eliminated as parent chlorate in the excreta of cattle, swine, and broilers. Under proposed dosing regimens, environmental burdens of excreted chlorate could be significant, especially in areas of intensive farming. Chlorate is highly water soluble and its transport through soil columns was not restricted by a variety of soils. In soil batch studies, chlorate was sparingly converted to chloride ion by a few soil types. In batch studies utilizing a mixture of soil, urine, and feces, chlorate was rapidly reduced to chloride under aerobic and anaerobic conditions. Rapid reduction under in vitro conditions implies a short environmental half life of chlorate under most waste-management systems.