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Title: Expressed gene sequences from the New World Screwworm, Cochiliomyia hominivorax

Author
item Saldivar, Leonel
item Guerrero, Felicito
item NENE, V - U OF MARYLAND, BALTIMORE

Submitted to: National Center for Biotechnology Information (NCBI)
Publication Type: Other
Publication Acceptance Date: 5/12/2008
Publication Date: 1/31/2009
Citation: Saldivar, L., Guerrero, F., Nene, V.M. 2009. Expressed gene sequences from the New World Screwworm, Cochiliomyia hominivorax. National Center for Biotechnology Information (NCBI). Available: http://ncbi.nlm.nih.gov. Assession numbers FG282693-FG291953 (Egg) and FG291954-FG301340 (Larvae).

Interpretive Summary: The New World screwworm, Cochliomyia hominivorax, was a devastating pest of livestock and other animals, including humans, throughout the US, Mexico, Central and South America. The female fly deposits its eggs at a wound site and the larval stage feeds on living tissue. During periods of heavy fly infestation and oviposition, death of the affected animal will often follow without human intervention. In the 1950s, annual losses to the US livestock industry topped $120 million. Although eradicated from North and Central America, the screwworm still is a pest in South America and the Caribbean. Reinfestation of North America is prevented by a sterile male release program conducted in Panama. We synthesized two DNA libraries from expressed genes of screwworm, using egg and second instar larvae as source material, and obtained 9,261 and 9,387 sequences from the egg and larval libraries, respectively. The 2 sets of sequences have been submitted and published under GenBank Accession Numbers FG282693-FG291953 (Egg) and FG291954-FG301340 (Larvae).

Technical Abstract: The New World screwworm, Cochliomyia hominivorax, was a devastating pest of livestock and other animals, including humans, throughout the US, Mexico, Central and South America. Although eradicated from North America, the screwworm still is a pest in South America and the Caribbean. Reinfestation of North and Central America is prevented by a sterile male release program conducted in Panama. We synthesized two cDNA libraries from screwworm egg and second instar larval source material, and obtained 9,261 and 9,387 sequences from the egg and larval libraries, respectively. The 2 sets of sequences have been submitted and published under GenBank Accession Numbers FG282693-FG291953 (Egg) and FG291954-FG301340 (Larvae).