ARS | Publication request: Use of Haplotypes to Estimate Mendelian Sampling Effects and Selection Limits

Submitted to: World Congress of Genetics Applied in Livestock Production
Publication Type: Abstract Only
Publication Acceptance Date: June 1, 2010
Publication Date: August 1, 2010
Citation: Cole, J.B., Van Raden, P.M. 2010. Use of Haplotypes to Estimate Mendelian Sampling Effects and Selection Limits. World Congress of Genetics Applied in Livestock Production. Proc. 9th World Congr. Genet. Appl. Livest. Prod., Leipzig, Germany, Aug. 1–6, abstr. p. 147.

Technical Abstract: Haplotypes of 3,689 Jersey cattle were used to derive upper and lower bounds for Mendelian sampling (MS) effects and selection limits. Matings of the 25 best and poorest bulls to all genotyped cows were simulated to determine the impact of genomic selection on MS. Lower and upper bounds of MS were 2,175 and 49,290, respectively. MS variance was slightly larger in the top group (58,149) than the bottom group (51,556). Upper and lower bounds for the selection limit were 5,243 and 13,254, respectively. For comparison, top U.S. Jersey bull in January, 2010, had a breeding value of +1,180. The MS variance from the top and bottom simulated matings was 31,022 and 47,820, respectively. Selecting animals rather than chromosomes may result in slower progress, but limits may be the same because chromosomes will become homozygous with either strategy.