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United States Department of Agriculture

Agricultural Research Service

Research Project: IDENTIFICATION OF DISEASE MECHANISMS AND CONTROL STRATEGIES FOR BACTERIAL RESPIRATORY PATHOGENS IN CATTLE Title: Abortion associated with Mycoplasma bovis (M. bovis) in a bison (Bison bison) herd

Authors
item Register, Karen
item Woodbury, Murry -
item Davies, Jennifer -
item Trujillo, Jesse -
item Perez-Casal, Jose -
item Burrage, Patrick -
item Clark, Edward -
item Windeyer, Clair -

Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: February 20, 2013
Publication Date: N/A

Technical Abstract: Mycoplasma bovis (M. bovis) has recently emerged as a significant health threat in bison and is an increasing concern and source of economic loss for producers. Clinical manifestations of infection documented in bison include pneumonia, respiratory distress and polyarthritis. The current study describes the isolation and identification of M. bovis from a bison cow and her aborted fetus. Necropsy of the cow revealed severe, caseonecrotic bronchopneumonia with chronic, fibrinous pleuritis and pulmonary sequestra, the typical features of pneumonic mycoplasmosis, as well as severe endometritis and necrotizing vasculitis and thrombosis of the placentome. Mycoplasma-like colonies, confirmed as M. bovis by multiple PCR assays and partial sequencing of the 16S rRNA gene, were cultured from maternal lung, uterus and kidney as well as fetal lung, kidney, abomasal fluid and placentome. Immunohistochemistry demonstrated M. bovis antigen in maternal lung and placentome. Additional analyses of tissues failed to implicate other bacterial or viral pathogens, including bovine herpesvirus 1, Bovine Viral Diarrhea Virus, Ureaplasma species and Tritrichomonas fetus. These data suggest that M. bovis-associated pneumonia in pregnant bison may be accompanied by hematogenous dissemination to the placentome, resulting in necrotizing placentitis and abortion. Veterinarians and producers should consider M. bovis when investigating the etiology of abortion in bison.

Last Modified: 11/23/2014
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