Submitted to: Methods in Molecular Biology
Publication Type: Book / Chapter
Publication Acceptance Date: March 10, 2014
Publication Date: June 30, 2014
Citation: Lager, K.M., Vincent, A.L. 2014. In vivo models for pathotyping and vaccine efficacy for swine influenza. In: Spackman, E., editor. Methods in Molecular Biology, Animal Influenza Virus. 2nd edition. New York, NY: Springer. p. 355-361. Technical Abstract: Swine influenza is a disease of the respiratory tract caused by influenza A virus (IAV). Experimental inoculation of pigs involves either aerosolization of virus and inhalation, or the direct introduction of virus into the upper or lower respiratory tract. This chapter covers methods for experimental IAV infection of pigs and collection of specific samples to study the pathogenesis of swine influenza and vaccine efficacy.