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United States Department of Agriculture

Agricultural Research Service

Research Project: Intervention Strategies to Control and Prevent Disease Outbreaks Caused by Avian Influenza and Other Emerging Poultry Pathogens

Location: Exotic and Emerging Avian Viral Diseases Research Unit

Title: The study of a reassortant H13N8 avian influenza virus

item Sharshov, K -
item Sivay, M -
item Liu, D -
item Pantin-Jackwood, Mary
item Marchenko, V -
item Durymanov, A -
item Alekseev, A -
item Damdindorj, T -
item Gao, G -
item Swayne, David
item Shestopalov, A -

Submitted to: Virus Genes
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: May 15, 2014
Publication Date: N/A

Interpretive Summary: A rarely identified influenza A virus of H13N8 subtype was isolated in Central Asia. We found the virus to be a reassortant avian influenza virus (AIV) from gulls in the Northern Hemisphere. We studied the pathogenic potential of such viruses. The data are very important for evolutionary ecology of gull-specific viruses; for the investigation of interspecies transmission and emergence of novel influenza viruses in wild nature.

Technical Abstract: A double reassortant H13N8 influenza A virus was isolated from gulls in Mongolia. The basic virological characteristics were studied. Complete genome sequence analysis indicated the complicated evolutionary history. The PA gene belongs to classical Avian-like lineage and more likely originated from non-gull avian virus pool. Data confirm the state of extensive geographic mosaicism in AIV from gulls in the Northern Hemisphere.

Last Modified: 7/24/2014
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