ARS | Publication request: Analysis of H7 avian influenza viruses by antigenic cartography and correlation to protection by vaccination

Submitted to: American Association of Avian Pathologists
Publication Type: Abstract Only
Publication Acceptance Date: December 23, 2008
Publication Date: July 13, 2009
Citation: Spackman, E., Swayne, D.E., Fouchier, R., Sarmento, L., Abbas, A. 2009. Analysis of H7 avian influenza viruses by antigenic cartography and correlation to protection by vaccination [abstract]. American Association of Avian Pathologists Annual Meeting, July 11-14, 2009, Seattle, Washington. 2009 CDROM.

Technical Abstract: The H7 hemagglutinin subtype one of the most common subtypes of avian influenza virus (AIV) in poultry world wide and since it has the potential to become highly pathogenic it is among the priority subtypes for vaccination. Selection of the optimal vaccine seed strains may now be aided by antigenic cartography, a relatively new method that can be used to analyze the antigenic relationship among influenza viruses based on hemagglutination inhibition data. Here we evaluate the antigenic relationship among H7 AIVs from poultry and attempt to correlate antigenic relationships with protection by vaccination to challenge with highly pathogenic AIV.