Technical Abstract: Microbial communities in honey bee colonies are essential for food processing and digestion. Symbiotic microbes also might contribute to the reduction of pathogens in the hive by synthesizing antimicrobial compounds. Environmental contaminants such as pesticides, fungicides and antibiotics could compromise the growth and diversity of a colony's microbial community and possibly impact the colony's health. There is little known about the beneficial microbes in honey bees and bee bread, and what is known is largely from studies conducted several decades ago. In the third part of this series, we present descriptions of studies that are needed such as metagenomic and functional metagenomic analyses of bee bread to expand our understanding of the contributions of microbes to food processing and utilization in honey bee colonies.