Author
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Duke, Stephen |
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Dayan, Franck |
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Submitted to: Toxins
Publication Type: Peer Reviewed Journal Publication Acceptance Date: 8/15/2011 Publication Date: 8/22/2011 Citation: Duke, S.O., Dayan, F.E. 2011. Modes of action of microbially-produced phytotoxins. Toxins. 3:1038-1064. Interpretive Summary: Increasing weed resistance to existing commercial herbicides has generated a new sense of urgency to discover and develop herbicides with new modes of action. Some of the most potent phytotoxins are synthesized by microbes. A few of these have molecular target sites that are the same as those of some synthetic herbicides, but many of them have unique target sites with potential for exploitation by the herbicide industry. Compounds from both non-pathogenic and pathogenic microbes are discussed. Microbial phytotoxins with modes of action the same as those of commercial herbicides and those with novel modes of action of action are covered. Examples of the compounds discussed are tentoxin, AAL-toxin, auscaulitoxin aglycone, hydantocidin, thaxtomin, and tabtoxin. Technical Abstract: Some of the most potent phytotoxins are synthesized by microbes. A few of these have molecular target sites that are the same as those of some synthetic herbicides, but many of them have unique target sites with potential for exploitation by the herbicide industry. Compounds from both non-pathogenic and pathogenic microbes are discussed. Microbial phytotoxins with modes of action the same as those of commercial herbicides and those with novel modes of action of action are covered. Examples of the compounds discussed are tentoxin, AAL-toxin, auscaulitoxin aglycone, hydantocidin, thaxtomin, and tabtoxin. |
