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United States Department of Agriculture

Agricultural Research Service

Research Project: NOVEL TECHNOLOGY FOR RENEWABLE RESOURCE UTILIZATION

Location: Renewable Product Technology Research Unit

Title: Bilayer properties of hydroxytyrosol- and tyrosol-phosphatidylcholine lipids

Authors
item Evans, Kervin
item Laszlo, Joseph
item Compton, David

Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: August 14, 2014
Publication Date: N/A

Technical Abstract: Tyrosol and hydroxytyrosol are the phytochemicals abundantly found in olive oil. Transphosphatidylation of tyrosol and hydroxytyrosol with dioleoylphosphocholine resulted in phospholipids with antioxidant properties. The ability of these phyto-phospholipids to form liposomes and supported bilayers were explored. The nanoscale forces (Van der Waals, hydrophobic force, electrostatic interactions) between lipid molecules limit the size of hydroxytyrosol-phosphatidylcholine liposomes to 86 ±7 nm in diameter; these forces also prove to make hydroxytyrosol- phosphatidylcholine liposomes quite robust and difficult to rupture on silica surfaces. Tyrosol- phosphatidylcholine, on the other hand, readily forms liposomes as small as 62 ±5 nm in diameter and will more easily rupture to form a supported bilayer. The rate of rupture on silica surfaces is demonstrated to be influenced by pH.

Last Modified: 11/27/2014
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