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ARS Home » Plains Area » Grand Forks, North Dakota » Grand Forks Human Nutrition Research Center » Healthy Body Weight Research » Research » Publications at this Location » Publication #308785
Title: A single dose of emulsified versus capsular fish oils has equivalent effects on chylomicron fatty acids over 8 hours

Author
item Raatz, Susan
item JOHNSON, LUANN - University Of North Dakota
item BIBUS, DOUGLAS - Lipid Technologies

Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 3/3/2014
Publication Date: 11/2/2014
Citation: Raatz, S.K., Johnson, L.K., Bibus, D. 2014. A single dose of emulsified versus capsular fish oils has equivalent effects on chylomicron fatty acids over 8 hours. Abstract presentation at: The Obesity Society Annual Meeting at ObesityWeekSM 2014; November 2-7,2014; Boston MA. www.obesityweek.com.

Interpretive Summary:

Technical Abstract: Long chain omega-3 fatty acids are important in nutrition and disease management. Flavored emulsified fish oil supplements provide an alternative to encapsulated fish oils. Oil in water emulsions may offer an advantage in bio-availability of the fatty acids. Chylomicrons transport triglyceride from the gut to the liver and other organs. We evaluated the effect of a single dose of three emulsified fish oils (Barleans Swirl™, Coromega Omega-3 Squeeze™, and Coromega Nectar™) vs. an encapsulated fish oil (Nordic Naturals™) on chylomicron fatty acid content over 8 hours. In a randomized, cross-over designed trial, participants consumed a single dose of fish oil supplement after a baseline blood draw. Additional samples were obtained at 2, 4 and 8 hours. Repeated measures ANOVA showed a reduction in percentage of 18:2n6 and the n6:n3 ratio and an increase in percentage of 20:5n3, 22:6n3,and total n3. However, no differences between treatments were observed in the 8 hour area-under-the-curve responses. Chylomicron fatty acid content was not different after intake of emulsified and capsular fish oil suggesting that absorption from the gut for the dose provided was the same for all supplements evaluated.