fixped.f90 | Checks pedigree relationships and discovers additional relatives | ||
Downloads | Program files and executable | ||
Input | Mostly the output files from findhap, version 3. Other input files are: |
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pedigree.file | Contains genotyped animals and their ancestors (same file used in findhap) Provides a more complete file than just known ancestors of genotyped animals |
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.../pedigrees.txt | Provides a more complete file than just known ancestors of genotyped animals | ||
clone.keys | Links known identical animals to one member of clone group | ||
For faster processing, input files from findhap can include only new animals and then link to the following full files from findhap that included all prior animals: |
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pedigree.priors | Same format as pedigree.file but for all prior animals | ||
hap.listpriors | hap.list from a prior full run | ||
hap.foundpriors | hap.found from a prior full run | ||
hap.filledpriors | hap.filled from a prior full run | ||
Steps |
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Output | bestmatches | Ancestor type: MGS, MGGS | |
Dam/maternal grandam (MGD) source codes: |
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0 | Unknown (no identification information) | ||
G | Genotyped | ||
I | Imputed | ||
P | Pedigree dam or MGD of genotyped animal (has identification information but not genotyped) | ||
Match: |
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0 | No likely MGS/MGGS found to replace unknown | ||
1 | Pedigree MGS/MGGS has most matches | ||
2 | Pedigree MGS/MGGS has 2nd most matches | ||
3 | Pedigree MGS/MGGS has 3rd most matches | ||
4+ | Pedigree MGS/MGGS has 3 or more bulls with more matches | ||
ADD | Add MGS/MGGS replacing missing | ||
DEL | Pedigree MGS/MGGS is unlikely, no better candidate found | ||
FIX | MGS/MGGS found, likely the true ancestor to replace genotyped one | ||
P | Pedigree MGS/MGGS not genotyped | ||
SUB | MGS/MGGS found, likely the true ancestor to replace nongenotyped one | ||
bestmatchesEXTRA |
Ancestor type: Dams, sires, full sibs, PGS, clones |
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Relative type: |
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CLON | Identical genotype | ||
DAM1 | Check and confirm if dam genotyped or delete if low match | ||
DAM2 | Output discovered dam if unknown but full sib has a dam | ||
DAM3 | Output discovered dam among daughters of MGS | ||
DAM4 | Discover dam and clones if neither sire nor MGS are genotyped | ||
SIRE | Sire | ||
FSIB | Full sib | ||
PGS | Paternal grandsire (top 3 listed may also include MGS) | ||
Match: |
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OK | Haplotypes confirm pedigree (used with CLON and FSIB) | ||
SUG | Discovered full sib has pedigree dam, but this full sib does not | ||
LOW | Reported sire has low number of matches; no better match found | ||
References | 2020 | Nani, J.P., L.R. Bacheller, J.B. Cole, and P.M. VanRaden. Discovering ancestors and connecting relatives in large genomic databases. J. Dairy Sci. 103:1729–1734. | |
2013 | VanRaden, P.M., T.A. Cooper, G.R. Wiggans, J.R. O'Connell, and L.R. Bacheller. Confirmation and discovery of maternal grandsires and great-grandsires in dairy cattle. J. Dairy Sci. 96:1874–1879. | ||
License | Fortran package fixped is public domain and was developed with U.S. taxpayer funding. Accurate results are not guaranteed. Please report any bugs to juanonani@gmail.com. You may modify, improve, use, and redistribute the code to anyone for any purpose. Or, you can ask Juan to make changes that could benefit U.S. evaluations and other users. | ||
Juan Nani
Paul VanRaden
Animal Genomics and Improvement Laboratory
Agricultural Research Service, USDA