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ARS Home » Northeast Area » Orono, Maine » National Cold Water Marine Aquaculture Center » People & Locations » Dina Proestou
Dina Proestou (PhD)
National Cold Water Marine Aquaculture Center
Research Geneticist

Phone: (401) 874-2175
Fax:

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Projects
Genetic Improvement of North American Atlantic Salmon and the Eastern Oyster for Aquaculture Production
In-House Appropriated (D)
  Accession Number: 437429
Establishment and Operation of the Regional Northeast Oyster Breeding Center (NOBC)
Non-Funded Cooperative Agreement (N)
  Accession Number: 441840
Oyster Aquaculture, Genomics, and Disease Research
Non-Funded Cooperative Agreement (N)
  Accession Number: 443577
On-Farm Grow-Out and Evaluation of USDA ARS Eastern Oyster Germplasm in Rhode Island
Non-Assistance Cooperative Agreement (S)
  Accession Number: 446360
Production of Pedigreed Families to Correlate Laboratory Disease Challenge Trials with Disease Acquisition in the Field
Non-Assistance Cooperative Agreement (S)
  Accession Number: 446363
Screening Eastern Oyster Populations for Optimal Aquaculture Performance
Non-Assistance Cooperative Agreement (S)
  Accession Number: 437772
Reassembly of the Eastern Oyster Genome with Advanced Assembly Pipelines
Non-Assistance Cooperative Agreement (S)
  Accession Number: 438524
Population Genomic Evaluation of Wild and Cultured Eastern Oyster Populations from the Northeast Region
Non-Assistance Cooperative Agreement (S)
  Accession Number: 440299
Genetic Improvement of North American Atlantic Salmon & the Eastern Oyster for Aquaculture Production
Non-Assistance Cooperative Agreement (S)
  Accession Number: 432776
Genetic Improvement of North American Atlantic Salmon and the Eastern Oyster for Aquaculture Production
Non-Assistance Cooperative Agreement (S)
  Accession Number: 437336

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Sex-specific gene expression in eastern oyster gonad and mantle tissues Reprint Icon - (Peer Reviewed Journal)
Proestou, D.A., Delomas, T.A., Sullivan, M.E., Markey Lundgren, K.R. 2024. Sex-specific gene expression in eastern oyster gonad and mantle tissues. Invertebrate Biology. 143(1):e12418. https://doi.org/10.1111/ivb.12418.
A second unveiling: haplotig masking of the eastern oyster genome improves population-level inference Reprint Icon - (Peer Reviewed Journal)
Puritz, J., Guo, X., Hare, M., He, Y., Hillier, L., Jin, S., Liu, M., Lotterhos, K., Minx, P., Modak, T., Proestou, D.A., Rice, E., Tomlison, C., Warren, W., Witkop, E., Zhao, H., Gomez-Chiarri, M. 2023. A second unveiling: haplotig masking of the eastern oyster genome improves population-level inference. Molecular Ecology Resources. https://doi.org/10.1111/1755-0998.13801.
Understanding Crassostrea virginica tolerance of Perkinsus marinus through global gene expression analysis Reprint Icon - (Peer Reviewed Journal)
Proestou, D.A., Sullivan, M.E., Markey Lundgren, K.R., Ben-Horin, T., Witkop, E.M., Hart, K.M. 2023. Understanding Crassostrea virginica tolerance of Perkinsus marinus through global gene expression analysis. Frontiers in Genetics. https://doi.org/10.3389/fgene.2023.1054558.
Development and evaluation of high-density SNP arrays for the eastern oyster Crassostrea virginica Reprint Icon - (Peer Reviewed Journal)
Guo, X., Puritz, J., Zhenwei, W., Proestou, D.A., Allen, S., Small, J., Verbyla, K., Zhao, H., Haggard, J., Chriss, N., Zeng, D., Markey Lundgren, K.R., Allam, B., Bushek, D., Gomez-Chiarri, M., Hare, M., Hollenbeck, C., Lapeyre, J., Liu, M., Lotterhos, K., Plough, L., Rawson, P., Rikard, S., Sallient, E., Varney, R., Wikfors, G., Wilbur, A. 2023. Development and evaluation of high-density SNP arrays for the eastern oyster Crassostrea virginica. Marine Biotechnology. https://doi.org/10.1007/s10126-022-10191-3.
Introducing the USDA/NEFSC Northeast Oyster Breeding Center (NOBC) - (Abstract Only)
Design and partial build of the Milford Laboratory CUDLS hatchery to support the Northeast Oyster Breeding Center - (Abstract Only)
Perkinsus marinus suppresses in vitro eastern oyster apoptosis via IAP-dependent and caspase-independent pathways involving TNFR, NF-kB, and oxidative pathway crosstalk. Reprint Icon - (Peer Reviewed Journal)
Witkop, E., Wikfors, G.H., Proestou, D.A., Markey Lundgren, K.R., Sullivan, M.E., Gomez-Chiarri 2022. Perkinsus marinus suppresses in vitro eastern oyster apoptosis via IAP-dependent and caspase-independent pathways involving TNFR, NF-kB, and oxidative pathway crosstalk. Developmental and Comparative Immunology. https://doi.org/10.1016/j.dci.2022.104339.
The expanded Inhibitor of Apoptosis gene family in oysters possesses novel domain architectures and may play diverse roles in apoptosis following immune challenge Reprint Icon - (Peer Reviewed Journal)
Witkop, E.M., Proestou, D.A., Gomez-Chiarri, M. 2022. The expanded Inhibitor of Apoptosis gene family in oysters possesses novel domain architectures and may play diverse roles in apoptosis following immune challenge. BMC Genomics. https://doi.org/10.1186/s12864-021-08233-6.
DEVELOPMENT AND EVALUATION OF HIGH-DENSITY SNP ARRAYS FOR THE EASTERN OYSTER CRASSOSTREA VIRGINICA - (Abstract Only)
Comparing the performance of selectively-bred and wild eastern oyster stocks in Rhode Island - (Abstract Only)
Survival and transcriptomic responses to differen perkinsus marinus exposure mentiods in and eastern oyster family - (Peer Reviewed Journal)
Sullivan, M., Proestou, D.A. 2021. Survival and transcriptomic responses to differen perkinsus marinus exposure mentiods in and eastern oyster family. Aquaculture. https://www.sciencedirect.com/science/article/pii/S0044848621004944?via%3Dihub.
Exceptional genome-wide copy number variation in the eastern oyster (Crassostrea virginica) Reprint Icon - (Peer Reviewed Journal)
Modak, T., Litterman, R., Puritz, J., Johnson, K., Roberts, E., Proestou, D.A., Guo, X., Gomez-Chiarri, M., Schwartz, R. 2021. Exceptional genome-wide copy number variation in the eastern oyster (Crassostrea virginica). Philosophical Transactions of the Royal Society B. https://doi.org/royalsocietypublishing.org/doi/10.1098/rstb.2020.0164.
Eastern oyster transcriptomic response to different Perkinsus marinus exposure methods and infection intensities - (Abstract Only)
The role of mitochondrial and lysosomal permeabilization in eastern oyster apoptotic response to Perkinsus marinus - (Abstract Only)
THE ROLE OF MITOCHONDRIAL AND LYSOSOMAL PERMEABILIZATION IN EASTERN OYSTER APOPTOTIC RESPONSE TO PERKINSUS MARINUS - (Abstract Only)
Genetic improvement of North American Atlantic salmon and the eastern oyster Crassostrea virginica at the U.S. Department of Agriculture-Agricultural Research Service National Cold Water Marine Aquaculture Center - (Peer Reviewed Journal)
Peterson, B.C., Burr, G.S., Pietrak, M.R., Proestou, D.A. 2020. Genetic improvement of North American Atlantic salmon and the eastern oyster Crassostrea virginica at the U.S. Department of Agriculture-Agricultural Research Service National Cold Water Marine Aquaculture Center. North American Journal of Aquaculture. 82:321-330.
From sequence to consequence: Genomic selection to expand and improve selective breeding for the eastern oyster - (Abstract Only)
Measuring the apoptotic response to Perkinsus Marinus in the eastern oyster using flow cytometry and tunel assay - (Abstract Only)
Mechanisms of eastern oyster, Crassostrea Virginica, hemocyte apoptosis in response to infection with Perkinsus Marinus - (Abstract Only)
Variation in global transcriptomatic response to Perkinsus marinus infection among Eastern oyster families highlights potential mechanisms of disease resistance - (Peer Reviewed Journal)
Proestou, D.A., Sullivan, M. 2019. Variation in global transcriptomatic response to Perkinsus marinus infection among Eastern oyster families highlights potential mechanisms of disease resistance. Fish and Shellfish Immunology. 96:141-151.
Mechanisms of hemocyte apoptosis in response to in vivo infection with perkinsus marinus in the eastern oyster crassostrea virginica - (Abstract Only)
Differences in global gene expression response to Dermo disease among eastern oyster families reveal mechanisms of resistance - (Abstract Only)
An analysis of population structure, genetic variation and outlier SNPs in the eastern oyster, Crassostrea virginica - (Abstract Only)
Defining demo resistance phenotypes in an eastern oyster breeding population - (Peer Reviewed Journal)
Proestou, D.A., Corbett, R., Ben-Horin, T., Small, J., Allen, S. 2019. Defining demo resistance phenotypes in an eastern oyster breeding population. Aquaculture Research. 50:2142-2154.
Assessing the contribution of aquaculture and restoration to wild oyster populations in a Rhode Island Coastal Lagoon Reprint Icon - (Peer Reviewed Journal)
Jaris, H., Brown, D.S., Proestou, D.A. 2019. Assessing the contribution of aquaculture and restoration to wild oyster populations in a Rhode Island Coastal Lagoon. Conservation Genetics. 20(3):503-516. https://doi.org/10.1007/s10592-019-01153-9.
Varied transcriptomic responses to Dermo disease within an eastern oyster breeding population - (Abstract Only)
Variation in tolerance to dermo disease within an eastern oyster breeding population - (Abstract Only)
Apoptosis phenotype and gene expression in response to the parasite Perkinsus marinus in the eastern oyster, Crassotrea virginica - (Abstract Only)
Disease at the interface of aquaculture and wild oyster reefs Reprint Icon - (Peer Reviewed Journal)
Ben-Horin, T., Burge, C., Bushek, D., Groner, M., Proestou, D.A., Huey, L., Bidegain, G., Carnegie, R. 2018. Disease at the interface of aquaculture and wild oyster reefs. Aquaculture Environment Interactions. 10:557-567. https://doi.org/10.3354/aei00290.
Investigating the role of apoptosis in disease resistance to dermo in the eastern oyster, Crassostrea virginica - (Abstract Only)
Genetic variation in anti-parasite behavior in oysters Reprint Icon - (Peer Reviewed Journal)
Ben-Horin, T., Allen Jr., S., Small, J., Proestou, D.A. 2018. Genetic variation in anti-parasite behavior in oysters. Marine Ecology Progress Series. 594:107-117. https://doi.org/10.3354/meps12511.
The eastern oyster genome: A resource for comparative genomics in shellfish aquaculture species - (Abstract Only)
Does restoring oyster reefs restore oyster health? - (Abstract Only)
Atlantic salmon and eastern oyster breeding programs at the National Cold Water Marine Aquaculture Center - (Proceedings)
Kristen Gruenthal, Clete Otoshi, Paul Olin, and Mike Rust (editors). 2017. Genetics and Breeding in Aquaculture: Proceedings of the 44th U.S.–Japan Aquaculture Panel Symposium, Seattle, WA, November 1, 2016. U.S. Dept. Commerce, NOAA Tech.Memo. NMFS-F/SPO-175, 78 p.
Aquaculture genomics, genetics and breeding in the United States: current status, challenges, and priorities for future research Reprint Icon - (Other)
Liu, Z., Leeds, T.D., Vallejo, R.L., Bosworth, B.G., Waldbieser, G.C., Palti, Y., Beck, B.H., Shoemaker, C.A., Blackburn, H.D., Rexroad III, C.E., Proestou, D.A. 2017. Aquaculture genomics, genetics and breeding in the United States: current status, challenges, and priorities for future research. Biomed Central (BMC) Genomics. 18:191. doi:10.1186/s12864-017-3557-1.
The genomic landscape of rapid, repeated evolutionary rescue from toxic pollution in wild fish - (Abstract Only)
The genomic landscape of rapid, repeated evolutionary rescue from toxic pollution in wild fish - (Peer Reviewed Journal)
Reid, N.M., Proestou, D.A., Clark, B.W., Warren, W.C., Colbourne, J.K., Shaw, J.R., Karchner, S.I., Hahn, M.E., Nacci, D., Oleksiak, M.F., Crawford, D.J., Whitehead, A. 2016. The genomic landscape of rapid, repeated evolutionary rescue from toxic pollution in wild fish. Science. 354(6317):1305-1308.
Atlantic salmon and eastern oyster breeding programs at the National Cold Water Marine Aquaculture Center - (Abstract Only)
Burr, G.S., Pietrak, M.R., Proestou, D.A., Peterson, B.C. 2016. Atlantic salmon and eastern oyster breeding programs at the National Cold Water Marine Aquaculture Center. U.S.-Japan Aquaculture Panel Symposium, Seattle, WA.
Genetic basis for evolved tolerance to dioxin-like pollutants in wild atlantic killifish: more than the aryl hydrocarbon receptor - (Peer Reviewed Journal)
Nacci, D., Proestou, D.A., Champlin, D., Martinson, J., Waits, E. 2016. Genetic basis for evolved tolerance to dioxin-like pollutants in wild atlantic killifish: more than the aryl hydrocarbon receptor. Molecular Ecology. 25(21):5467-5482.
An integrated genetic linkage map and comparative genome analysis for the estuarine Atlantic killifish, Fundulus heteroclitus - (Peer Reviewed Journal)
Waits, E., Martinson, J., Riner, B., Morris, S., Proestou, D.A., Champlin, D., Nacci, D. 2016. An integrated genetic linkage map and comparative genome analysis for the estuarine Atlantic killifish, Fundulus heteroclitus. Open Journal of Genetics. 6:28-38.
Performance of selected eastern oyster lines across northeastern US estuaries - (Peer Reviewed Journal)
Proestou, D.A., Corbett, R., Vinyard, B.T., Piesz, J., Guo, X., Rawson, P., Allen, S.K., Gomez-Chiarri, M. 2016. Performance of selected eastern oyster lines across northeastern US estuaries. Aquaculture. 464, pp. 17-27.
The performance of oyster families exposed to Dermo disease is contingent on the source of pathogen exposure - (Abstract Only)
Genetic basis for evolved tolerance to dioxin-like pollutants in wild Atlantic killifish: more than the aryl hydrocarbon receptor - (Abstract Only)
Developing tools for the study of molluscanimmunity: The sequencing of the genome of the eastern oyster, Crassostreavirginica - (Peer Reviewed Journal)
Gomez-Chiarri, M., Warren, W., Guo, X., Proestou, D.A. 2015. Developing tools for the study of molluscanimmunity: The sequencing of the genome of the eastern oyster, Crassostreavirginica. Fish and Shellfish Immunology. 46(1), pp. 2-4.
The use of –omic tools in the study of disease processes in marine bivalves - (Review Article)
Gomez Chiarri, M., Guo, X., Tanguy, A., He, Y., Proestou, D.A. 2015. The use of –omic tools in the study of disease processes in marine bivalves. Journal of Invertebrate Pathology. 131, pp. 137-154.
Assessing the extent of phenotypic variation for dermo resistance among selectively-bred families of the Eastern Oyster, Crassostrea virginica - (Abstract Only)
Proestou, D.A., Corbett, R., Gomez Chiarri, M., Moss Small, J., Allen, S. 2015. Assessing the extent of phenotypic variation for dermo resistance among selectively-bred families of the Eastern Oyster, Crassostrea virginica. Journal of Shellfish Research. 34(2):718.
Markers associated with disease resistance in Eastern oysters, Crassostrea virginica - (Abstract Only)
Bao, K., Gomez Chiarri, M., Proestou, D.A. 2015. Markers associated with disease resistance in Eastern oysters, Crassostrea virginica. Journal of Shellfish Research. 34(2):608.
Characterization of phenotypic variation for dermo resistance among selectively-bred families of the Eastern oyster, Crassostrea virginica - (Abstract Only)
Corbett, R., Gomez Chiarri, M., Moss Small, J., Allen Jr., S., Proestou, D.A. 2015. Characterization of phenotypic variation for dermo resistance among selectively-bred families of the Eastern oyster, Crassostrea virginica. Journal of Shellfish Research. 34(2):620.
Assessing the contribution of aquaculture and restoration to wild oyster populations in Rhode Island - (Abstract Only)
Jarris, H., Brown, D., Gomez-Chiarri, M., Proestou, D.A. 2014. Assessing the contribution of aquaculture and restoration to wild oyster populations in Rhode Island. Journal of Shellfish Research. 33(2):620.
Evaluating the performance of selective-bred lines of eastern oysters, Crassostrea virginica, at different locations along the east coast of the United States - (Abstract Only)
Bao, K., Corbett, R., Proestou, D.A., Frank-Lawale, A., Guo, X., Rawson, P., Allen, S., Gomez-Chiarri, M. 2014. Evaluating the performance of selective-bred lines of eastern oysters, Crassostrea virginica, at different locations along the east coast of the United States. Journal of Shellfish Research. 33(2):589.
Disease management strategies for shellfish aquaculture: the important role of hatcheries - (Abstract Only)
Gomez-Chiarri, M., Rowley, D., Nelson, D., Proestou, D.A., Frank-Lawale, A., Allen, S., Guo, X., Rawson, P. 2014. Disease management strategies for shellfish aquaculture: the important role of hatcheries. Journal of Shellfish Research. 33(2):554.
Targeted approach to identify genetic loci associated with evolved dioxin tolerance in Atlantic Killifish (Fundulus heteroclitus) Reprint Icon - (Peer Reviewed Journal)
Proestou, D.A., Flight, P., Champlin, D., Nacci, D. 2014. Targeted approach to identify genetic loci associated with evolved dioxin tolerance in Atlantic Killifish (Fundulus heteroclitus). BMC Evolutionary Biology. 14:7.