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Steven Conrad
Endemic Poultry Viral Diseases Research
Biologist

Phone: (706) 546-3134
Fax:

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Projects
Systems Biology Approaches to Develop Medical Countermeasures to Detect, Prevent, and Control Poultry Production Viral Diseases
In-House Appropriated (D)
  Accession Number: 441471
Elucidate Host-Pathogen Interactions of Polymicrobial Infections in Broiler Chicken Production
Non-Assistance Cooperative Agreement (S)
  Accession Number: 444438
Develop Novel Vaccines Against Avian Reovirus and to Elucidate Mechanisms of Viral Pathogenesis
Non-Assistance Cooperative Agreement (S)
  Accession Number: 444938

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Construction of recombinant Marek’s disease virus vaccine expressing sigma C proteins of avian reoviruses - (Abstract Only)
Whole genomic constellation of avian reovirus strains isolated from broilers with arthritis in North Carolina, USA Reprint Icon - (Peer Reviewed Journal)
Nour, I., Alvarez Narvaez, S., Harrell, T.L., Conrad, S.J., Mohanty, S.K. 2023. Whole genomic constellation of avian reovirus strains isolated from broilers with arthritis in North Carolina, USA. Viruses. 15:2191. https://doi.org/10.3390/v15112191.
Toll-like receptor ligands enhance vaccine efficacy against a virulent Newcastle disease virus challenge in chickens Reprint Icon - (Peer Reviewed Journal)
Lee, C.W., Bakre, A.A., Olivier, T.L., Alvarez Narvaez, S., Harrell, T.L., Conrad, S.J. 2023. Toll-like receptor ligands enhance vaccine efficacy against a virulent Newcastle disease virus challenge in chickens. Pathogens. 12(10):1230. https://doi.org/10.3390/pathogens12101230.
Optimizing the conditions for whole-genome sequencing of avian reoviruses Reprint Icon - (Peer Reviewed Journal)
Alvarez Narvaez, S., Harrell, T.L., Oluwayinka, O., Sellers, H.S., Khalid, Z., Hauck, R., Chowdhury, E.U., Conrad, S.J. 2023. Optimizing the conditions for whole-genome sequencing of avian reoviruses. Viruses. 15(9):1938. https://doi.org/10.3390/v15091938.
Targeted ablation of exon 2 of the Avian Leukosis Virus-A (ALV-A)receptor gene in a chicken fibroblast cell line by CRISPR abrogates ALV-A infection Reprint Icon - (Peer Reviewed Journal)
Conrad, S.J., Mays, J.K., Hearn, C.J., Dunn, J.R. 2023. Targeted ablation of exon 2 of the Avian Leukosis Virus-A (ALV-A)receptor gene in a chicken fibroblast cell line by CRISPR abrogates ALV-A infection. Avian Diseases. 67(1):102-107. https://doi.org/10.1637/aviandiseases-D-22-00072.
Identification and validation of Ikaros (IKZF1) as a cancer driver gene for Marek’s disease virus-induced lymphomas Reprint Icon - (Peer Reviewed Journal)
Steep, A., Hildebrandt, E.C., Xu, H., Hearn, C.J., Frishman, D., Niikura, M., Dunn, J.R., Kim, T.N., Conrad, S.J., Muir, W.M., Cheng, H.H. 2022. Identification and validation of Ikaros (IKZF1) as a cancer driver gene for Marek’s disease virus-induced lymphomas. Microorganisms. 10(2):401. https://doi.org/10.3390/microorganisms10020401.
Deletion of the viral thymidine kinase in a meq-deleted recombinant Marek's disease virus reduces lymphoid atrophy but is less protective Reprint Icon - (Peer Reviewed Journal)
Conrad, S.J., Oluwayinka, E.B., Mays, J.K., Heidari, M., Dunn, J.R. 2021. Deletion of the viral thymidine kinase in a meq-deleted recombinant Marek's disease virus reduces lymphoid atrophy but is less protective. Microorganisms. 10(1):7. https://doi.org/10.3390/microorganisms10010007.
Deletion of thymidine kinase reduces protection of Marek’s disease vaccine candidate - (Abstract Only)
Dunn, J.R., Conrad, S.J., Oluwayinka, E., Mays, J.K., Heidari, M. 2021. Deletion of thymidine kinase reduces protection of Marek’s disease vaccine candidate. American Association of Avian Pathologists. Deletion of thymidine kinase reduces protection of Marek's disease vaccine candidate [abstract].
The Secretion of Type I Interferons as a Primary Determinant of Susceptibility to Marek’s Disease Virus in Chickens - (Abstract Only)
Codon deoptimization of UL54 in meq-deleted Marek's disease vaccine candidate eliminates lymphoid atrophy but reduces vaccinal protection Reprint Icon - (Peer Reviewed Journal)
Conrad, S.J., Hearn, C.J., Silva, R.F., Dunn, J.R. 2020. Codon deoptimization of UL54 in meq-deleted Marek's disease vaccine candidate eliminates lymphoid atrophy but reduces vaccinal protection. Avian Diseases. 64(3):243-246. https://doi.org/10.1637/aviandiseases-D-19-00166.