Barbara Shukitt-Hale
(PhD)
Boston, Massachusetts
Research Psychologist
Phone: (617) 556-3118
Fax: (617) 556-3222
(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)
Publications
(Clicking on the reprint icon
will take you to the publication reprint.)
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Galactic cosmic ray particle exposure does not increase inflammation or oxidative stress in rat microglial cells in vitro
- (Peer Reviewed Journal)
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Cahoon, D., Fisher, D.R., Rabin, B.M., Lamon-Fava, S., Wu, D., Zheng, T., Shukitt Hale, B. 2024. Galactic cosmic ray particle exposure does not increase inflammation or oxidative stress in rat microglial cells in vitro. International Journal of Molecular Sciences. 25(11):5923. https://doi.org/10.3390/ijms25115923.
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Effects of HZE particle exposure location and energy on brain inflammation and oxidative stress in rats
- (Peer Reviewed Journal)
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Cahoon, D., Rabin, B., Fisher, D.R., Shukitt Hale, B. 2023. Effects of HZE particle exposure location and energy on brain inflammation and oxidative stress in rats. Radiation Research. 200(5):431-443. https://doi.org/10.1667/RADE-22-00041.1.
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Extracts from green leafy vegetables and berries, and their major polyphenolics, reduce inflammatory stress signals in HAPI rat microglial cells, in vitro
- (Abstract Only)
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Fisher, D.R., Marschall, S.N., Zheng, T., Shukitt Hale, B. 2023. Extracts from green leafy vegetables and berries, and their major polyphenolics, reduce inflammatory stress signals in HAPI rat microglial cells, in vitro. [Abstract] Society for Neuroscience Meeting 2023. Program #PSTR203.17.
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Perspective: Challenges and Future Directions in Clinical Research with Nuts and Berries
- (Other)
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Zuelch, M.L., Radtke, M.D., Holt, R.R., Basu, A., Burton-Freeman, B., Ferruzzi, M.G., Li, Z., Shay, N.F., Shukitt Hale, B., Keen, C.L., Steinberg, F.M., Hackman, R.M. 2023. Perspective: Challenges and Future Directions in Clinical Research with Nuts and Berries. Advances in Nutrition. https://doi.org/10.1016/j.advnut.2023.07.010.
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A randomised controlled trial to investigate the cognitive, mood and metabolic effects of acute oyster mushroom intervention in older adults (OYSACO)
- (Abstract Only)
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Cha, S., Bell, L., Shukitt Hale, B., Williams, C. 2023. A randomised controlled trial to investigate the cognitive, mood and metabolic effects of acute oyster mushroom intervention in older adults (OYSACO). [Abstract] 4th International Conference on Food Bioactives and Health. Abstract #FBHC23-0131.
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Council for Responsible Nutrition science in session. Optimizing health with nutrition - opportunities, gaps and the future
- (Literature Review)
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Ho, E., Drake, V.J., Michels, A., Nkrumah-Elie, Y.M., Brown, L.L., Scott, J.M., Newman, J.W., Shukitt Hale, B., Soumyanath, A., Chilton, F.H., Lindemann, S.R., Shao, A., Hazels-Mitmesser, S., Mitmesser, S. 2023. Council for Responsible Nutrition science in session. Optimizing health with nutrition - opportunities, gaps and the future. Advances in Nutrition. 14:948-958. https://doi.org/10.1016/j.advnut.2023.05.015.
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Red raspberry supplemented serum reduces inflammatory stress signals in HAPI rat microglial cells, in vitro
- (Abstract Only)
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Fisher, D.R., Piccolo, F.X., Xiao, D., Burton-Freeman, B.M., Shukitt Hale, B. 2023. Red raspberry supplemented serum reduces inflammatory stress signals in HAPI rat microglial cells, in vitro. [Abstract]. 7(Suppl 1):101220. https://doi.org/10.1016/j.cdnut.2023.101220.
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Low vitamin K intake negatively affects cognition and hippocampal neurogenesis in C57 BL6 mice
- (Abstract Only)
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Zheng, T., Fu, X., Shen, X., Marschall, S., Smith, D., Tarr, A., Mykyten, K., Biederer, T., Shukitt Hale, B., Booth, S. 2023. Low vitamin K intake negatively affects cognition and hippocampal neurogenesis in C57 BL6 mice. [Abstract]. 7(Suppl 1):101202. https://doi.org/10.1016/j.cdnut.2023.101202.
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Effects of preexposure to a subthreshold dose of helium particles on the changes in performance produced by exposure to helium particles
- (Peer Reviewed Journal)
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Rabin, B.M., Miller, M.G., Shukitt Hale, B. 2023. Effects of preexposure to a subthreshold dose of helium particles on the changes in performance produced by exposure to helium particles. Life Sciences in Space Research. 37:88-96. https://doi.org/10.1016/j.lssr.2023.03.003.
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Dietary blueberry before and/or after stressor exposure attenuates neuroinflammation, oxidative stress, and cognitive deficits in rats
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Dietary responses of dementia-related genes encoding metabolic enzymes
- (Peer Reviewed Journal)
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Parnell, L.D., Magadmi, R., Zwanger, S., Shukitt Hale, B., Lai, C., Ordovas, J.M. 2023. Dietary responses of dementia-related genes encoding metabolic enzymes. Nutrients. 15(3):644. https://doi.org/10.3390/nu15030644.
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Phytochemical combination is more effective than individual components in reducing stress signaling in rat hippocampal neurons and microglia
- (Peer Reviewed Journal)
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Fisher, D.R., Zheng, T., Bielinski, D.F., Kelly, M.E., Cahoon, D.S., Shukitt Hale, B. 2022. Phytochemical combination is more effective than individual components in reducing stress signaling in rat hippocampal neurons and microglia. International Journal of Molecular Sciences. 23(20):12651. https://doi.org/10.3390/ijms232012651.
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Protective effects of a polyphenol-rich blueberry extract on adult human neural progenitor cells
- (Peer Reviewed Journal)
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Zheng, T., Bielinski, D.F., Fisher, D.R., Zhang, J., Shukitt Hale, B. 2022. Protective effects of a polyphenol-rich blueberry extract on adult human neural progenitor cells. Molecules. 27(19):6152. https://doi.org/10.3390/molecules27196152.
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Raspberry phenolics in serum from supplemented adults reduce inflammatory stress signals in HAPI rat microglial cells, in vitro
- (Abstract Only)
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Fisher, D.R., Piccolo, F.X., Xiao, M., Burton-Freeman, B., Shukitt Hale, B. 2022. Raspberry phenolics in serum from supplemented adults reduce inflammatory stress signals in HAPI rat microglial cells, in vitro [abstract]. Society for Neuroscience Abstracts 2022. Program No. 621.10.
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The potential cognitive health impact of berries
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Shukitt Hale, B. 2022. The potential cognitive health impact of berries [abstract]. Journal of Natural Health Product Research. 4:18. https://doi.org/10.33211/jnhpr.28.
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Long-term supplementation with fruits and vegetables prevents Western-style high-fat diet-induced cognitive impairment in mice
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Weimin, G., Shukitt Hale, B., Dayong, W., Li, L., Ortega, E., Meydani, S. 2022. Long-term supplementation with fruits and vegetables prevents Western-style high-fat diet-induced cognitive impairment in mice [abstract]. Current Developments in Nutrition. 6(Suppl 1):790. https://doi.org/10.1093/cdn/nzac064.009.
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Low vitamin K intake negatively affects C57BL6 mouse survival and cognition
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Zheng, T., Fu, X., Shen, X., Marschall, S., Smith, D., Tarr, A., Biederer, T., Shukitt Hale, B., Booth, S. 2022. Low vitamin K intake negatively affects C57BL6 mouse survival and cognition [abstract]. Current Developments in Nutrition. 6(Suppl 1):816. https://doi.org/10.1093/cdn/nzac064.035.
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Dietary blueberry before and/or after exposure to HZE particles attenuates neuroinflammation, oxidative stress, and cognitive deficits in rats
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Cahoon, D.S., Fisher, D.R., Zheng, T., Rabin, B.M., Shukitt Hale, B. 2022. Dietary blueberry before and/or after exposure to HZE particles attenuates neuroinflammation, oxidative stress, and cognitive deficits in rats [abstract]. Virtual Online NASA Human Research Program Investigators Workshop. Abstract #1133-000326.
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Blueberry treatment administered before and/or after lipopolysaccharide stimulation and oxidative stress in rat microglial cells
- (Peer Reviewed Journal)
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Cahoon, D.S., Fisher, D.R., Lamon-Fava, S., Wu, D., Zheng, T., Shukitt Hale, B. 2022. Blueberry treatment administered before and/or after lipopolysaccharide stimulation and oxidative stress in rat microglial cells. Nutritional Neuroscience. 26:127-137. https://doi.org/10.1080/1028415X.2021.2020404.
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Berry bioactives and cognition
- (Book / Chapter)
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Bell, L., Shukitt Hale, B., Williams, C.M. 2022. Berry bioactives and cognition. In: Klimis-Zacas, Dorothy and Rodriguez-Mateos, Ana., editors. Berries and Berry Bioactive Compounds in Promoting Health. Cambridge, U.K. Royal Society of Chemistry. p. 185-207.
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Blueberry extract attenuates neuroinflammation and oxidative stress when administered before and/or after lipopolysaccharide in rat microglial cells
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Cahoon, D., Fisher, D.R., Shukitt Hale, B. 2021. Blueberry extract attenuates neuroinflammation and oxidative stress when administered before and/or after lipopolysaccharide in rat microglial cells. [abstract]. 2021 Society for Neuroscience Annual Meeting. Program #181.07.
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Modeling space radiation-induced cognitive dysfunction using targeted and non-targeted effects
- (Peer Reviewed Journal)
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Shuryak, I., Brenner, D.J., Blattnig, S.R., Shukitt Hale, B., Rabin, B.M. 2021. Modeling space radiation-induced cognitive dysfunction using targeted and non-targeted effects. Scientific Reports. 11:8845. https://doi.org/10.1038/s41598-021-88486-z.
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Walnut oil and blueberry treatments have beneficial individual but not synergistic effects on neuroinflammation in vitro
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Fisher, D.R., Cahoon, D., Shukitt Hale, B. 2021. Walnut oil and blueberry treatments have beneficial individual but not synergistic effects on neuroinflammation in vitro. Current Developments in Nutrition. 5(Suppl 2):904. https://doi.org/10.1093/cdn/nzab049_017.
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Blueberry treatment administered before and/or after lipopolysaccharide attenuates neuroinflammation and oxidative stress in rat microglial cells
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Cahoon, D., Fisher, D.R., Shukitt Hale, B. 2021. Blueberry treatment administered before and/or after lipopolysaccharide attenuates neuroinflammation and oxidative stress in rat microglial cells. Current Developments in Nutrition. 5(Suppl 2):899. https://doi.org/10.1093/cdn/nzab049_012.
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The impact of a walnut-rich breakfast on cognitive performance throughout the day in healthy young adults
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Bell, L., Dodd, G.F., Whyte, A.R., Shukitt Hale, B., Williams, C.M. 2021. The impact of a walnut-rich breakfast on cognitive performance throughout the day in healthy young adults. Current Developments in Nutrition. 5(Suppl 2):895. https://doi.org/10.1093/cdn/nzab049_008.
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Berry phenolics are associated with cognitive enhancement in blueberry- and strawberry-supplemented older adults
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Rutledge, G.A., Miller, M.G., Sandhu, A.K., Edirisinghe, I., Burton-Freeman, B., Shukitt Hale, B. 2021. Berry phenolics are associated with cognitive enhancement in blueberry- and strawberry-supplemented older adults. Current Developments in Nutrition. 5(Suppl 2):921. https://doi.org/10.1093/cdn/nzab049_034.
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Blueberries and insulin protect microglial cells against high glucose-induced inflammation and restore GLUT-1
- (Peer Reviewed Journal)
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Hininger-Favier, I., Thangthaeng, N., Bielinski, D.F., Fisher, D.R., Shukitt Hale, B., Poulose, S.M. 2021. Blueberries and insulin protect microglial cells against high glucose-induced inflammation and restore GLUT-1. Journal of Berry Research. 11(2):201-216. https://doi.org/10.3233/JBR-200628.
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Healthy aging: Nutrition matters, start early and screen often
- (Review Article)
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Roberts, S., Silver, R., Das, S., Fielding, R.A., Gilhooly, C., Jacques, P.F., Kelly, J.M., Mason, J.B., McKeown, N.M., Rearson, M., Rowan, S., Saltzman, E., Shukitt-Hale, B., Smith, C.E., Taylor, A., Wu, D., Zhang, F., Panetta, K., Booth, S.L. 2021. Healthy aging: Nutrition matters, start early and screen often. Advances in Nutrition. https://doi.org/10.1093/advances/nmab032.
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Dietary strawberry improves cognition in a randomized, double-blind, placebo-controlled trial using older adults
- (Peer Reviewed Journal)
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Miller, M.G., Thangthaeng, N., Scott, T.M., Rutledge, G.A., Shukitt Hale, B. 2021. Dietary strawberry improves cognition in a randomized, double-blind, placebo-controlled trial using older adults. British Journal of Nutrition. 126(20):253-263. https://doi.org/10.1017/S0007114521000222.
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Effects of preexposure to 4He particles on the alteration of cognitive performance produced by exposure to 56Fe particles in male and female rats
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Rabin, B.M., Rottman, V., Shukitt Hale, B. 2021. Effects of preexposure to 4He particles on the alteration of cognitive performance produced by exposure to 56Fe particles in male and female rats. [abstract] NASA Human Research Program IWS 2021 (online), Program #1105-002.
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Mechanistically-based model development for space radiation risk assessment: Modeling space radiation induced cognitive dysfunction using targeted and non-targeted effects
- (Abstract Only)
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Brenner, D.J., Shuryak, I., Blattnig, S.R., Shukitt Hale, B., Rabin, B.M. 2021. Mechanistically-based model development for space radiation risk assessment: Modeling space radiation induced cognitive dysfunction using targeted and non-targeted effects. [abstract] NASA Human Research Program IWS 2021 (online), Program #1105-002219.
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Blueberry phenolics are associated with cognitive enhancement in healthy supplemented older adults
- (Peer Reviewed Journal)
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Rutledge, G.A., Sandhu, A.K., Miller, M.G., Edirisinghe, I., Burton-Freeman, B.B., Shukitt Hale, B. 2020. Blueberry phenolics are associated with cognitive enhancement in healthy supplemented older adults. Food and Function. 12:107-118. https://doi.org/10.1039/D0FO02125C.
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Effects of partial or whole-body exposures to 56Fe particles on brain function and cognitive performance in rats
- (Peer Reviewed Journal)
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Cahoon, D., Shukitt Hale, B., Bielinski, D.F., Hawkins, E.M., Cacioppo, A.M., Rabin, B.M. 2020. Effects of partial or whole-body exposures to 56Fe particles on brain function and cognitive performance in rats. Life Sciences in Space Research. 27:56-63. https://doi.org/10.1016/j.lssr.2020.07.006.
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Effects of housing on rodent behavior: wire vs solid plastic caging
- (Peer Reviewed Journal)
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Miller, M., Smith, D., Shukitt Hale, B. 2020. Effects of housing on rodent behavior: wire vs solid plastic caging. Animal Husbandry, Dairy and Veterinary Science. 4:1-5.
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Supplementation with a novel combination of fruits and vegetables prevented high fat diet-induced cognitive impairment in mice
- (Abstract Only)
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Guo, W., Shukitt Hale, B., Wu, D., Li, L., Ortega, E.F., Liu, Y., Thomas, M., Nikolova-Karakashian, M., Meydani, M., Meydani, S.N. 2020. Supplementation with a novel combination of fruits and vegetables prevented high fat diet-induced cognitive impairment in mice [abstract]. Current Developments in Nutrition. https://doi.org/10.1093/cdn/nzaa057_023.
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The Potential Cognitive Health Impact of Strawberries
- (Abstract Only)
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Shukitt Hale, B. 2020. The Potential Cognitive Health Impact of Strawberries [abstract]. Nutrition Trends Forum 2020 Meeting.
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Dietary starch composition effects on Cx43-intercellular communication channels and short-term memory
- (Abstract Only)
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Francisco, S., Smith, K., Rowan, S., Aragones Bargallo, G., Smith, D.E., Shukitt Hale, B., Taylor, A., Bejarano Fernandez, E. 2020. Dietary starch composition effects on Cx43-intercellular communication channels and short-term memory. Current Developments in Nutrition. 4(2):1205. https://doi.org/10.1093/cdn/nzaa057_021.
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Beneficial effects of blueberry extracts on adult human neural progenitor cells
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Bielinski, D.F., Fisher, D.R., Shukitt Hale, B., Zheng, T. 2020. Beneficial effects of blueberry extracts on adult human neural progenitor cells. Current Developments in Nutrition. 4(Suppl_2):1191. https://meeting.nutrition.org.
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The effects of blueberry and strawberry serum metabolites on age-related oxidative and inflammatory signaling
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Rutledge, G.A., Fisher, D.R., Miller, M.G., Kelly, M.E., Bielinski, D.F., Shukitt Hale, B. 2020. The effects of blueberry and strawberry serum metabolites on age-related oxidative and inflammatory signaling [abstract]. Program book for Translational Research Day, Poster #20, p. 14.
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The effects of blueberry and strawberry serum metabolites on age-related oxidative and inflammatory signaling in vitro
- (Peer Reviewed Journal)
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Rutledge, G.A., Fisher, D.R., Miller, M.G., Kelly, M.E., Bielinski, D.F., Shukitt Hale, B. 2019. The effects of blueberry and strawberry serum metabolites on age-related oxidative and inflammatory signaling in vitro. Food and Function. 10(12):7707-7713. https://doi.org/10.1039/C9FO01913H.
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Dietary modulation of the effects of exposure to HZE particles on cognitive performance
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Rabin, B.M., Rottman, V., Jiang, V., Hull, M.T., Ingram, I., Shukitt Hale, B. 2020. Dietary modulation of the effects of exposure to HZE particles on cognitive performance [abstract]. 2020 NASA Human Research Program Investigators Workshop, Program #20188.
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Walnut-associated fatty acids inhibit LPS-induced activation of BV-2 microglia
- (Peer Reviewed Journal)
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Carey, A.N., Fisher, D.R., Bielinski, D.F., Cahoon, D.S., Shukitt Hale, B. 2020. Walnut-associated fatty acids inhibit LPS-induced activation of BV-2 microglia. Inflammation. 43(1):241-250.
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Factors involved in the beneficial effects of blueberries on cognition
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Shukitt Hale, B. 2019. Factors involved in the beneficial effects of blueberries on cognition. 2019 Wild Blueberry Associaton of North America (WBANA) Neuroscience Roundtable.
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An evidence map of walnut intake and cognitive outcomes
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Shukitt Hale, B. 2019. An evidence map of walnut intake and cognitive outcomes. 2019 Health Research Conference.
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Effects of exposure to 12C and 4He particles on cognitive performance of intact and ovariectomized female rats
- (Peer Reviewed Journal)
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Rabin, B.M., Miller, M.G., Larsen, A., Spadafora, C., Zolnerowich, N.N., Dell'Acqua, L.A., Shukitt Hale, B. 2019. Effects of exposure to 12C and 4He particles on cognitive performance of intact and ovariectomized female rats. Life Sciences in Space Research. 22:47-54. https://doi.org/10.1016/j.lssr.2019.07.005.
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Blueberry extract attenuates the in vitro expression of oxidative stress and inflammation markers in adult human neural progenitor cells
- (Abstract Only)
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Bielinski, D.F., Shukitt Hale, B., Steindler, D.A., Zheng, T. 2019. Blueberry extract attenuates the in vitro expression of oxidative stress and inflammation markers in adult human neural progenitor cells [abstract]. Society for Neuroscience Abstracts and Proceedings. 2019 Society for Neuroscience Annual Meeting Program #208.14.
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Individual and synergistic effects of walnut oil and blueberry treatments on reducing neuroinflammation in rat microglial cells in vitro
- (Abstract Only)
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Fisher, D.R., Cahoon, D.S., Shukitt Hale, B. 2020. Individual and synergistic effects of walnut oil and blueberry treatments on reducing neuroinflammation in rat microglial cells in vitro [abstract]. Society for Neuroscience Abstracts and Proceedings. 2019 Society for Neuroscience Annual Meeting Program # 208.13.
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Factors involved in the beneficial effects of polyphenols on neurochemical and behavioral changes in aging
- (Abstract Only)
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Shukitt Hale, B., Miller, M.G., Fisher, D.R., Rutledge, G.A., Bielinski, D.F., Scott, T.M. 2019. Factors involved in the beneficial effects of polyphenols on neurochemical and behavioral changes in aging [abstract]. ICoFF2019 program book, Abstract #SY21-4, p. 49.
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Serum from aged humans supplemented with blueberry or strawberry reduces inflammatory stress signals in HAPI rat microglial cells, in vitro
- (Abstract Only)
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Rutledge, G.A., Fisher, D.R., Miller, M.G., Thangthaeng, N., Kelly, M.E., Bielinski, D.F., Shukitt Hale, B. 2019. Serum from aged humans supplemented with blueberry or strawberry reduces inflammatory stress signals in HAPI rat microglial cells, in vitro [abstract]. 2019 Berry Health Benefits Symposium Pre-Proceedings, p.87.
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Effects of head-only or whole-body exposure to very low doses of 4He (1000 MeV/n) particles on neuronal function and cognitive performance
- (Peer Reviewed Journal)
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Rabin, B.M., Poulose, S.M., Bielinski, D.F., Shukitt Hale, B. 2019. Effects of head-only or whole-body exposure to very low doses of 4He (1000 MeV/n) particles on neuronal function and cognitive performance. Life Sciences in Space Research. 20:85-92. https://doi.org/10.1016/j.lssr.2019.02.001.
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Blueberries improve neuroinflammation and cognition differentially depending on individual cognitive baseline status
- (Peer Reviewed Journal)
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Shukitt Hale, B., Nopporn, T., Miller, M.G., Poulose, S.M., Fisher, D.R. 2019. Blueberries improve neuroinflammation and cognition differentially depending on individual cognitive baseline status. Journal of Gerontology Biological Science. https://doi.org/10.1093/gerona/glz048.
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Partial body exposures to HZE particles: role of oxidative stress in the disruption of neuronal function and cognitive performance
- (Abstract Only)
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Rabin, B.M., Switzer, R., Cahoon, D., Poulose, S.M., Rottman, V., Hurd, P., Willats, L., Cacioppo, A., Chigurupati, S., Shukitt Hale, B. 2019. Partial body exposures to HZE particles: role of oxidative stress in the disruption of neuronal function and cognitive performance [abstract]. 2019 NASA Human Research Program Investigators Workshop. Program #19331.
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Whole foods and the role of diet in cognition/brain health
- (Abstract Only)
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Shukitt Hale, B. 2018. Whole foods and the role of diet in cognition/brain health [abstract]. California Walnut Commission Scientific and Health Research Meeting 2018 Program, page #28.
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In vitro effects of a polyphenol-rich blueberry extract on adult human neural progenitor cells
- (Abstract Only)
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Zheng, T., Bielinski, D.F., Fisher, D.R., Shukitt Hale, B., Steindler, D.A. 2018. In vitro effects of a polyphenol-rich blueberry extract on adult human neural progenitor cells [abstract]. 2018 Society for Neuroscience Annual Meeting Program # 291.16.
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The effects of intermittent wild blueberry feeding on inflammation and motor and cognitive behavior
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Fisher, D.R., Cahoon, D., Miller, M.G., Bielinski, D.F., Shukitt Hale, B. 2018. The effects of intermittent wild blueberry feeding on inflammation and motor and cognitive behavior [abstract]. 2018 Society for Neuroscience Annual Meeting Program # 291.17.
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Role of estrogen in mediating the effects of exposure to space radiation on cognitive performance in female rats
- (Abstract Only)
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Rabin, B.M., Miller, M.G., Hawkins, E.M., Larsen, A., Spadafora, C., Zolnerowich, N.N., Dell'Acqua, L.A., Pagden, W., Rottman, V., Shukitt Hale, B. 2018. Role of estrogen in mediating the effects of exposure to space radiation on cognitive performance in female rats [abstract]. 2018 Society for Neuroscience Annual Meeting Program # 593.03.
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Berry fruit differentially improves age-related decrements in behavior based on baseline status
- (Abstract Only)
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Shukitt Hale, B., Miller, M.G., Bielinski, D.F., Fisher, D.R. 2018. Berry fruit differentially improves age-related decrements in behavior based on baseline status [abstract]. American Chemical Society Abstracts. 256th American Chemical Society National Meeting & Exposition Program. #AGFD 24.
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Berry polyphenols are associated with enhanced cognition and reduced inflammation in healthy, older adults
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Shukitt Hale, B., Miller, M.G., Fisher, D.R., Bielinski, D.F., Scott, T.M. 2018. Berry polyphenols are associated with enhanced cognition and reduced inflammation in healthy, older adults [abstract]. 256th American Chemical Society National Meeting & Exposition Program #AGFD 21.
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Protective effects of foods containing flavonoids on age-related cognitive decline
- (Review Article)
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Gildawie, K.R., Galli, R.L., Shukitt Hale, B., Carey, A.N. 2018. Protective effects of foods containing flavonoids on age-related cognitive decline. Current Nutrition Reports. https://doi.org/10.1007/s13668-018-0227-0.
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Neurochemical changes in specific regions of rat brain following partial or whole body exposures to 56Fe particles
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Shukitt Hale, B., Poulose, S.M., Bielinski, D.F., Miller, M.G., Carrihill-Knoll, K.L., Rabin, B.M. 2018. Neurochemical changes in specific regions of rat brain following partial or whole body exposures to 56Fe particles [abstract]. COSPAR 2018 Scientific Assembly Abstracts F2.1-0014-18, p. 1905.
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Changes in neuronal function and cognitive performance following exposure to very low doses of helium particles
- (Abstract Only)
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Rabin, B., Poulose, S.M., Miller, M.M., Bielinski, D.F., Hawkins, E.M., Larsen, A., Spadafora, C., Zolnerowich, N.N., Dell'Acqua, L.C., Shukitt Hale, B. 2018. Changes in neuronal function and cognitive performance following exposure to very low doses of helium particles [abstract]. COSPAR 2018 Scientific Assembly Abstracts #F2.1-0013-18, p. 1904.
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Dietary intervention with blueberries and Epidiferphane (EDP) enhances calcium buffering in rat hippocampal neurons and reduces stress signaling in microglial cells
- (Abstract Only)
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Shukitt Hale, B., Fisher, D.R., Bielinski, D.F., Steindler, D., Zheng, T. 2018. Dietary intervention with blueberries and Epidiferphane (EDP) enhances calcium buffering in rat hippocampal neurons and reduces stress signaling in microglial cells [abstract]. Current Developments in Nutrition. 2(11):nzy043.
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Polyphenol- and PUFA-rich walnuts protect against age-associated cognitive decline through epigenetic modulation
- (Abstract Only)
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Poulose, S., Shukitt Hale, B. 2017. Polyphenol- and PUFA-rich walnuts protect against age-associated cognitive decline through epigenetic modulation. [abstract]. American Chemical Society Abstracts. 253rd American Chemical Society National Meeting Program #AGFD 201.
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Metabolic fate of strawberry polyphenols after chronic intake in healthy older adults
- (Peer Reviewed Journal)
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Sandhu, A.K., Miller, M.G., Thangthaeng, N., Scott, T.M., Shukitt Hale, B., Edirisinghe, I., Burton-Freeman, B. 2018. Metabolic fate of strawberry polyphenols after chronic intake in healthy older adults. Food & Function. 9:96-106.
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Age as a factor in the responsiveness of the organism to the disruption of cognitive performance by exposure to HZE particles differing in linear energy transfer
- (Peer Reviewed Journal)
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Rabin, B.M., Carrihill-Knoll, K.L., Miller, M.G., Shukitt Hale, B. 2018. Age as a factor in the responsiveness of the organism to the disruption of cognitive performance by exposure to HZE particles differing in linear energy transfer. Life Sciences in Space Research. 16:84-92. https://doi.org/10.1016/j.lssr.2017.12.001.
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Raspberry differentially improves age-related declines in psychomotor function dependent on baseline motor ability
- (Peer Reviewed Journal)
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Shukitt Hale, B., Thangthaeng, N., Kelly, M.E., Smith, D.E., Miller, M.G. 2017. Raspberry differentially improves age-related declines in psychomotor function dependent on baseline motor ability. Food & Function. 8:4752-4759. http://dx.doi.org/10.1039/c7fo00894e.
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Walnut extract modulates activation of microglia through alteration in intracellular calcium concentration
- (Peer Reviewed Journal)
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Thangthaeng, N., Poulose, S., Fisher, D.R., Shukitt Hale, B. 2017. Walnut extract modulates activation of microglia through alteration in intracellular calcium concentration. Nutrition Research. 49:88-95. https://doi.org/10.1016/j.nutres.2017.10.016.
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Effects of exposure to HZE particles on the cognitive performance of ovariectomized and intact female rats
- (Abstract Only)
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Rabin, B.M., Carrihill-Knoll, K.L., O'Conor, S., Miller, M.G., Shukitt Hale, B. 2018. Effects of exposure to HZE particles on the cognitive performance of ovariectomized and intact female rats. Meeting Abstract. 2018 NASA Human Research Program Investigators Workshop, Program #18428.
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Blueberry supplementation attenuates microglia activation and increases neuroplasticity in mice consuming a high fat diet
- (Peer Reviewed Journal)
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Carey, A.N., Gildawie, K.R., Rovnak, A., Thangthaeng, N., Fisher, D.R., Shukitt Hale, B. 2017. Blueberry supplementation attenuates microglia activation and increases neuroplasticity in mice consuming a high fat diet. Nutritional Neuroscience. https://doi.org/10.1080/1028415X.2017.1411875.
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Nutritional factors affecting adult neurogenesis and cognitive function
- (Review Article)
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Poulose, S.M., Miller, M.G., Scott, T., Shukitt Hale, B. 2017. Nutritional factors affecting adult neurogenesis and cognitive function. Advances in Nutrition. 8:804-811.
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The relationship between berry polyphenols, inflammation, and cognitive function in older adults
- (Abstract Only)
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Shukitt Hale, B., Miller, M.G., Sandhu, A.K., Fisher, D.R., Scott, T.M., Burton-Freeman, B. 2017. The relationship between berry polyphenols, inflammation, and cognitive function in older adults [abstract]. E:\Papers\174-TopR-118.pdf.
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Food for thought: how diet influences cognitive function and emotion
- (Peer Reviewed Journal)
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Spencer, S.J., Korosi, A., Laye, S., Shukitt Hale, B., Barrientos, R.M. 2017. Food for thought: how diet influences cognitive function and emotion. NPJ Science of Food. 1(7). https://doi.org/10.1038/s41538-017-0008-y.
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Effect of blueberry and insulin on glucose-induced neurotoxicity in rat microglial cells
- (Abstract Only)
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Hininger, I., Thangthaeng, N., Bielinski, D., Fisher, D.R., Shukitt Hale, B., Poulose, S. 2017. Effect of blueberry and insulin on glucose-induced neurotoxicity in rat microglial cells. 8th International Conference on Polyphenols and Health (ICPH 2017) Abstract# 03-053.
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In vitro effects of Epidiferphane™ on adult human neural progenitor cells
- (Abstract Only)
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Zheng, T., Bielinski, D., Fisher, D.R., Shukitt Hale, B., Reynolds, B., Steindler, D. 2017. In vitro effects of Epidiferphane™ on adult human neural progenitor cells. Society for Neuroscience Abstracts and Proceedings. Program #667.14.
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Blueberry and EpidiferphaneTM (EDP) enhance calcium buffering in rat hippocampal cells and reduce stress signalling in microglial cells
- (Abstract Only)
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Fisher, D.R., Zheng, T., Bielinski, D.F., Steindler, D., Shukitt Hale, B. 2017. Blueberry and EpidiferphaneTM (EDP) enhance calcium buffering in rat hippocampal cells and reduce stress signalling in microglial cells. Society for Neuroscience Abstracts and Proceedings. Program #667.15.
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Berry phenolics are associated with cognitive enhancement in blueberry- and strawberry-supplemented healthy older adults
- (Abstract Only)
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Miller, M.G., Sandhu, A.K., Thangthaeng, N., Scott, T.M., Burton-Freeman, B.B., Shukitt Hale, B. 2017. Berry phenolics are associated with cognitive enhancement in blueberry- and strawberry-supplemented healthy older adults. Society for Neuroscience Abstracts and Proceedings. Program #667.16.
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Exposure to low doses of helium particles disrupts neuronal function and cognitive performance
- (Abstract Only)
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Rabin, B.M., Poulose, S.M., Miller, M.G., Bielinski, D.F., Carrihill-Knoll, K.L., Hawkins, E.M., Heng, R.C., Larsen, A., Spadafora, C., Zolnerowich, N.N., Patel, R., Shukitt Hale, B. 2017. Exposure to low doses of helium particles disrupts neuronal function and cognitive performance. Society for Neuroscience Abstracts and Proceedings. Program #396.08.
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Metabolic fate of blueberry anthocyanins after chronic supplementation in healthy older adults
- (Abstract Only)
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Sandhu, A., Miller, M.G., Shukitt Hale, B., Edirisinghe, I., Burton-Freeman, B. 2017. Metabolic fate of blueberry anthocyanins after chronic supplementation in healthy older adults. [abstract]. Journal of Federation of American Societies for Experimental Biology. 31: 646.20.
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Dietary blueberry improves cognition among older adults in a randomized, double-blind, placebo-controlled trial
- (Peer Reviewed Journal)
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Miller, M.G., Hamilton, D.A., Joseph, J.A., Shukitt Hale, B. 2017. Dietary blueberry improves cognition among older adults in a randomized, double-blind, placebo-controlled trial. European Journal of Nutrition. 57:1169-1180. https://doi.org/10.1007/s00394-017-1400-8.
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Association between plasma phenolics and improved cognition in blueberry-supplemented older adults
- (Abstract Only)
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Miller, M.G., Sandhu, A., Burton-Freeman, B., Shukitt Hale, B. 2017. Association between plasma phenolics and improved cognition in blueberry-supplemented older adults [abstract]. 2017 Berry Health Benefits Symposium Pre-Proceedings, p. 88.
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Metabolic fate of strawberry polyphenols after chronic supplementation in healthy older adults
- (Abstract Only)
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Sandhu, A., Miller, M.G., Thangthaeng, N., Scott, T.M., Shukitt Hale, B., Edirisinghe, I., Burton-Freeman, B. 2017. Metabolic fate of strawberry polyphenols after chronic supplementation in healthy older adults [abstract]. 2017 Berry Health Benefits Symposium Pre-Proceedings, 2017 Berry Health Benefits Symposium, March 28-30, 2017, Pismo Beach, California. p. 86.
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The relationship between anthocyanins found in berry fruit, inflammation, and cognitive function in older adults
- (Abstract Only)
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Shukitt Hale, B., Miller, M.G., Thangthaeng, N., Fisher, D.R., Sandhu, A., Burton-Freeman, B. 2017. The relationship between anthocyanins found in berry fruit, inflammation, and cognitive function in older adults [abstract]. 9th International Workshop on Anthocyanins. p. 16.
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Role of fruits, nuts, and vegetables in maintaining cognitive health
- (Review Article)
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Miller, M.G., Thangthaeng, N., Poulose, S.M., Shukitt Hale, B. 2017. Role of fruits, nuts, and vegetables in maintaining cognitive health. Experimental Gerontology. 94:24-28. doi: 10.1016/j.exger.2016.12.014.
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Effects of blueberries on inflammation, motor performance and cognitive function
- (Abstract Only)
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Shukitt Hale, B., Miller, M.G., Thangthaeng, N., Fisher, D.R., Bielinski, D.F., Kelly, M.E., Scott, T. 2017. Effects of blueberries on inflammation, motor performance and cognitive function [abstract]. 21st International Association of Gerontology & Geriatrics (IAGG) World Congress, July 23-27, 2017, San Francisco, CA. doi:https://doi.org/10.1093/geroni/igx004.5010.
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A clinically relevant frailty index for aging rats
- (Peer Reviewed Journal)
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Miller, M.G., Thangthaeng, N., Shukitt Hale, B. 2017. A clinically relevant frailty index for aging rats. Journal of Gerontology, Series A, Biological Sciences and Medical Sciences. doi:10.1093/gerona/glw338.
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Neurochemical differences in learning and memory paradigms among rats supplemented with anthocyanin-rich blueberry diets and exposed to acute doses of 56Fe particles
- (Peer Reviewed Journal)
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Poulose, S.M., Rabin, B.M., Bielinski, D.F., Kelly, M.E., Miller, M.G., Thangthaeng, N., Shukitt Hale, B. 2017. Neurochemical differences in learning and memory paradigms among rats supplemented with anthocyanin-rich blueberry diets and exposed to acute doses of 56Fe particles. Life Sciences in Space Research. 12:16-23.
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Age as a factor in the responsiveness of the organism to the disruption of cognitive performance by exposure to HZE particles differing in LET
- (Abstract Only)
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Rabin, B.M., Carrihill-Knoll, K., Barton, K., Miller, M.G., Shukitt Hale, B. 2017. Age as a factor in the responsiveness of the organism to the disruption of cognitive performance by exposure to HZE particles differing in LET. [Abstract]. NASA Human Research Program Investigators' Workshop, Program #17172.
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Effects of head-only or whole-body exposure to very low doses of 4HE (1000 MeV/n) particles
- (Abstract Only)
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Rabin, B.M., Poulose, S., Miller, M.G., Bielinski, D.F., Kelly, M.E., Carrihill-Knoll, K.L., Patel, R., Hawkins, E., Heng, R., Shukitt Hale, B. 2017. Effects of head-only or whole-body exposure to very low doses of 4HE (1000 MeV/n) particles. [Abstract]. NASA Human Research Program Investigators' Workshop, Program #17271.
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Tart cherry extracts reduce inflammatory and oxidative stress signaling in microglial cells
- (Peer Reviewed Journal)
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Shukitt Hale, B., Kelly, M.E., Bielinski, D.F., Fisher, D.R. 2016. Tart cherry extracts reduce inflammatory and oxidative stress signaling in microglial cells. Antioxidants. doi: 10.3390/antiox5040033.
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The beneficial effects of berry fruit on cognitive and neuronal function in aging
- (Abstract Only)
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Shukitt Hale, B., Miller, M.G., Thangthaeng, N., Fisher, D.R., Bielinski, D.F., Kelly, M.E., Scott, T. 2016. The beneficial effects of berry fruit on cognitive and neuronal function in aging. In: Proceedings of the 20th International Conference. Functional and Medical Foods for Chronic Diseases:Bioactive Compounds and Biomarkers, September 22-23, 2016, Boston, Massachusetts. p. 289-290.
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Tart cherry supplementation improves working memory, hippocampal inflammation and autophagy in aged rats
- (Peer Reviewed Journal)
|
Thangthaeng, N., Poulose, S., Gomes, S.M., Miller, M.G., Bielinski, D., Shukitt Hale, B. 2016. Tart cherry supplementation improves working memory, hippocampal inflammation and autophagy in aged rats. Age. 38:393-404. doi: 10.1007/s11357-016-9945-7.
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Age as a risk factor for the disruption of cognitive performance by exposure to the types of radiation encounted on exploratory class missions to other planets
- (Abstract Only)
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Rabin, B.M., Shukitt Hale, B., Carrhill-Knoll, K.L., Miller, M.G., Barton, K. 2016. Age as a risk factor for the disruption of cognitive performance by exposure to the types of radiation encounted on exploratory class missions to other planets. Society for Neuroscience Abstracts and Proceedings. Program No.743.04.
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A clinically relevant frailty index for aging rats
- (Abstract Only)
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Miller, M.G., Thangthaeng, N., Scott, T.M., Shukitt Hale, B. 2016. A clinically relevant frailty index for aging rats. Society for Neuroscience Abstracts and Proceedings. Program No. 596.17.
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Raspberry supplementation alleviates age-related motor dysfunction in select populations
- (Abstract Only)
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Thangthaeng, N., Miller, M.G., Kelly, M.E., Smith, D.E., Shukitt Hale, B. 2016. Raspberry supplementation alleviates age-related motor dysfunction in select populations. Society for Neuroscience Abstracts and Proceedings. Program No. 596-18.
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The effects of blueberry and strawberry serum metabolites on age-related oxidative and inflammatory signaling in vitro
- (Abstract Only)
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Fisher, D.R., Miller, M.G., Thangthaeng, N., Kelly, M.E., Bielinski, D.F., Shukitt Hale, B. 2016. The effects of blueberry and strawberry serum metabolites on age-related oxidative and inflammatory signaling in vitro. Society for Neurscience 2016 Abstracts. Program No. 596.19.
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Advances in berry research: the sixth biennial berry health benefits symposium
- (Proceedings)
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Seeram, N.P., Shukitt Hale, B. 2016. Advances in berry research: the sixth biennial berry health benefits symposium. Journal of Berry Research. 6:93-95.
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The effects of blueberries on cognition and neuroplasticity
- (Abstract Only)
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Carey, A.N., Rovnak, A.M., Gildawie, K.R., Fisher, D.R., Shukitt Hale, B. 2016. The effects of blueberries on cognition and neuroplasticity. [abstract]. 252nd American Chemical Society National Meeting, Program #AGFD 161.
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Berry fruit can improve age-associated neuronal and cognitive deficits: from the laboratory to the clinic
- (Abstract Only)
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Shukitt Hale, B., Miller, M.G., Thangthaeng, N., Fisher, D.R., Bielinski, D., Kelly, M.E., Tammy, S. 2016. Berry fruit can improve age-associated neuronal and cognitive deficits: from the laboratory to the clinic. American Aging Association. 72:61.
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Preserving brain function in aging: The anti-glycative potential of berry fruit
- (Review Article)
|
Thangthaeng, N., Poulose, S.M., Miller, M.G., Shukitt Hale, B. 2016. Preserving brain function in aging: the anti-glycative potential of berry fruit. NeuroMolecular Medicine. 18:465-473, doi: 10.1007/s12017-016-8400-3.
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Dietary strawberry improves cognition in older adults: a randomized, double-blind, placebo-controlled study
- (Abstract Only)
|
Miller, M.G., Thangthaeng, N., Scott, T.M., Shukitt Hale, B. 2016. Dietary strawberry improves cognition in older adults: a randomized, double-blind, placebo-controlled study. Federation of American Societies for Experimental Biology Conference. vol. 30 no. 1 Supplement 679.18.
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Anthocyanin-rich blueberry diets enhance protection of critical brain regions exposed to acute levels of 56Fe cosmic radiation
- (Abstract Only)
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Poulose, S.M., Kelly, M.E., Bielinski, D.F., Miller, M.G., Rabin, B.M., Shukitt Hale, B. 2016. Anthocyanin-rich blueberry diets enhance protection of critical brain regions exposed to acute levels of 56Fe cosmic radiation. Federation of American Societies for Experimental Biology Conference. Vol. 30 No. 1 Supplement 679.4.
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Red raspberries can improve motor function in aged rats
- (Peer Reviewed Journal)
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Galli, R.L., Carey, A.N., Luskin, K.A., Bielinski, D.F., Shukitt Hale, B. 2016. Red raspberries can improve motor function in aged rats. Journal of Berry Research. 6:97-103.
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Modulation of oxidative stress, inflammation, autophagy and expression of Nrf2 in hippocampus and frontal cortex of rats fed with acai-enriched diets
- (Peer Reviewed Journal)
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Poulose, S.M., Bielinski, D.F., Carey, A., Schauss, A.G., Shukitt Hale, B. 2016. Modulation of oxidative stress, inflammation, autophagy and expression of Nrf2 in hippocampus and frontal cortex of rats fed with acai-enriched diets. Nutritional Neuroscience. doi: 10.1080/1028415X.2015.1125654.
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Dietary supplementation with the polyphenol-rich açaí pulps (Euterpe oleracea Mart. and Euterpe precatoria Mart.) improves cognition in aged rats and attenuates inflammatory signaling in BV-2 microglial cells
- (Peer Reviewed Journal)
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Carey, A., Miller, M.G., Fisher, D.R., Bielinski, D., Gilman, C.K., Poulose, S.M., Shukitt Hale, B. 2017. Dietary supplementation with the polyphenol-rich açaí pulps (Euterpe oleracea Mart. and Euterpe precatoria Mart.) improves cognition in aged rats and attenuates inflammatory signaling in BV-2 microglial cells. Nutritional Neuroscience. 20:238-245.
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Daily supplementation with mushroom (Agaricus bisporus) improves balance and working memory in aged rats
- (Peer Reviewed Journal)
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Thangthaeng, N., Miller, M., Gomes, S., Shukitt Hale, B. 2015. Daily supplementation with mushroom (Agaricus bisporus) improves balance and working memory in aged rats. Nutrition Research. 35:1079-1084.
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The beneficial effects of berries on cognition, motor behavior, and neuronal function in aging
- (Peer Reviewed Journal)
|
Shukitt Hale, B., Bielinski, D., Lau, F., Willis, L.M., Carey, A., Joseph, J. 2015. The beneficial effects of berries on cognition, motor behavior, and neuronal function in aging. British Journal of Nutrition. 114:1542–1549. doi:10.1017/S0007114515003451.
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Effects of pterostilbene and resveratrol on brain and behavior
- (Review Article)
|
Poulose, S.M., Thangthaeng, N., Miller, M.G., Shukitt Hale, B. 2015. Effects of pterostilbene and resveratrol on brain and behavior. Neurochemistry International. 89:227-233.
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Comparison of the effectiveness of exposure to low LET helium particles (4He) and gamma rays (137Cs) on the disruption of cognitive performance
- (Peer Reviewed Journal)
|
Rabin, B.M., Carrihihll-Knoll, K.L., Shukitt Hale, B. 2015. Comparison of the effectiveness of exposure to low LET helium particles (4He) and gamma rays (137Cs) on the disruption of cognitive performance. Radiation Research. 184:266-272.
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Effects of berry supplementation on mobility and cognition among older adults
- (Abstract Only)
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Miller, M.G., Shukitt Hale, B. 2015. Effects of berry supplementation on mobility and cognition among older adults. Berry Health Benefits Symposium, 2015 Berry Health Benefits Symposium Pre-Proceedings; October 13-15, 2015,Madison, Wisconsin, p. 24-25.
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Effects of strawberry supplementation on mobility and cognition in older adults
- (Abstract Only)
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Miller, M.G., Thangthaeng, N., Scott, T.M., Shukitt Hale, B. 2015. Effects of strawberry supplementation on mobility and cognition in older adults. Society for Neuroscience Abstracts and Proceedings. Program #767.05.
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Aging and walnut-rich diet supplementation affects the expression of immediate-early genes in critical brain regions
- (Abstract Only)
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Poulose, S.M., Bielinski, D.F., Crott, J.W., Roe, A.J., Thangthaeng, N., Shukitt Hale, B. 2015. Aging and walnut-rich diet supplementation affects the expression of immediate-early genes in critical brain regions. Society for Neuroscience Abstracts and Proceedings. Society for Neuroscience Abstracts 2015, Program #767.04.
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Blueberries affect neuroinflammation and cognition differentially depending on individual cognitive baseline status
- (Abstract Only)
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Thangthaeng, N., Miller, M.G., Poulose, S.M., Bielinski, D.F., Fisher, D.R., Shukitt Hale, B. 2015. Blueberries affect neuroinflammation and cognition differentially depending on individual cognitive baseline status. Society for Neuroscience Abstracts and Proceedings. Society for Neuroscience Abstracts 2015, Program #767.03.
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The effects of nutrition on cognition and motor function in aging
- (Abstract Only)
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(Program Booklet) Nutraceuticals in Neurodegeneration and Aging, Satellite meeting to the 25th ISN-13th APSN Biennial Meeting, 2015 (no page numbers exist)Shukitt Hale, B. 2015. The effects of nutrition on cognition and motor function in aging. Meeting Abstract.
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Polyphenols found in berry fruit improve age-associated changes in cognitive function and brain inflammation
- (Abstract Only)
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Shukitt Hale, B. 2015. Polyphenols found in berry fruit improve age-associated changes in cognitive function and brain inflammation. Polyphenols Actualites [abstract]. 7th International Conference on Polyphenols and Health (Program), p. 50.
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Acute effects of exposure to 56Fe and 16O particles on learning and memory
- (Peer Reviewed Journal)
|
Rabin, B.M., Poulose, S.M., Carrihill-Knoll, K.L., Ramirez, F., Bielinski, D.F., Heroux, N., Shukitt Hale, B. 2015. Acute effects of exposure to 56Fe and 16O particles on learning and memory. Radiation Research. 184:143-150.
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Walnuts improve neuronal and behavioral function in aging
- (Abstract Only)
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Shukitt Hale, B., Thangthaeng, N., Fisher, D.R., Bielinski, D.F., Poulose, S.M. 2015. Walnuts improve neuronal and behavioral function in aging. Federation of European Nutrition Societies European Nutrition Conference. Annals of Nutrition and Metabolism. Vol. 67 (Suppl. 1) p. 463.
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Effect of blueberries and insulin on glucose induced neurotoxicity in brain cells in vitro
- (Abstract Only)
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Hininger-Favier, I., Thangthaeng, N., Shukitt Hale, B., Poulose, S. 2015. Effect of blueberries and insulin on glucose induced neurotoxicity in brain cells in vitro. Federation of European Nutrition Societies European Nutrition Conference. Annals of Nutrition and Metabolism (2015), vol 67 (Suppl.1), p. 467-468.
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Lack of reliability in the disruption of cognitive performance following exposure to protons
- (Peer Reviewed Journal)
|
Rabin, B.M., Heroux, N.A., Shukitt Hale, B., Carrihill-Knoll, K.L., Beck, Z., Baxter, C. 2015. Lack of reliability in the disruption of cognitive performance following exposure to protons. Radiation and Environmental Biophysics. 54:285-295.
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Effects of dietary blueberry on cognition and in vivo and in vitro inflammatory status
- (Abstract Only)
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Miller, M.G., Fisher, D.R., Kelly, M.E., Bielinski, D.F., Shukitt Hale, B. 2015. Effects of dietary blueberry on cognition and in vivo and in vitro inflammatory status. Federation of American Societies for Experimental Biology Conference. 29:900.2.
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Effects of aging and walnut diet on DNA methylation and expression of immediate-early genes in critical brain regions
- (Abstract Only)
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Poulose, S.M., Bielinski, D.F., Crott, J.W., Roe, A.J., Thangthaeng, N., Shukitt Hale, B. 2015. Effects of aging and walnut diet on DNA methylation and expression of immediate-early genes in critical brain regions. Federation of American Societies for Experimental Biology Conference. FASEB Journal - EB abstracts 2015.
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Differential effects of blueberry polyphenols on age-associated neuroinflammation and cognition
- (Abstract Only)
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Thangthaeng, N., Miller, M.G., Poulose, S.M., Bielinski, D.F., Fisher, D.R., Shukitt Hale, B. 2015. Differential effects of blueberry polyphenols on age-associated neuroinflammation and cognition. Federation of American Societies for Experimental Biology Conference. 29:756-758.
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Protective effects of blueberry and strawberry diets on neuronal stress following exposure to 56Fe particles
- (Peer Reviewed Journal)
|
Poulose, S.M., Bielinski, D., Carrihill-Knoll, K.L., Rabin, B.M., Shukitt Hale, B. 2014. Protective effects of blueberry and strawberry diets on neuronal stress following exposure to 56Fe particles. Brain Research. 1593:9-18.
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Serum metabolites from walnut-fed aged rats attenuate stress-induced neurotoxicity in BV-2 microglial cells
- (Peer Reviewed Journal)
|
Fisher, D.R., Poulose, S.M., Bielinski, D.F., Shukitt Hale, B. 2014. Serum metabolites from walnut-fed aged rats attenuate stress-induced neurotoxicity in BV-2 microglial cells. Nutritional Neuroscience. 20(2):103-109. doi: 10.1179/1476830514Y.0000000150.
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Effects of age on the disruption of cognitive performance by exposure to space radiation
- (Peer Reviewed Journal)
|
Rabin, B., Shukitt Hale, B., Carrihill-Knoll, K. 2014. Effects of age on the disruption of cognitive performance by exposure to space radiation. Journal of Behavioral and Brain Science. 4:297-307.
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Mobility and cognition: End points for dietary interventions in aging
- (Peer Reviewed Journal)
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Miller, M.G., Hamilton, D.A., Joseph, J.A., Shukitt Hale, B. 2014. Mobility and cognition: End points for dietary interventions in aging. Nutrition and Aging. 2:213-222.
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Serum metabolites from blueberry-supplemented older adults attenuate stress-induced neurotoxicity in HAPI microglial cells dependent on baseline cognitive status
- (Abstract Only)
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Shukitt Hale, B., Miller, M.G., Fisher, D.R. 2014. Serum metabolites from blueberry-supplemented older adults attenuate stress-induced neurotoxicity in HAPI microglial cells dependent on baseline cognitive status. Society for Neuroscience Abstracts and Proceedings. 2014. Program #144.16.
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Effects of dietary blueberry supplementation on older adults
- (Abstract Only)
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Miller, M.G., Joseph, J.A., Shukitt Hale, B. 2014. Effects of dietary blueberry supplementation on older adults. Society for Neuroscience Abstracts and Proceedings. 2014 Program #144.19.
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Tart cherry extracts reduce inflammatory stress signaling and enhance calcium buffering in microglial and neuronal cell lines
- (Abstract Only)
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Fisher, D.R., Bielinski, D., Kelly, M.E., Shukitt Hale, B. 2014. Tart cherry extracts reduce inflammatory stress signaling and enhance calcium buffering in microglial and neuronal cell lines. Society for Neuroscience Abstracts and Proceedings 2014. Program #144.18.
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Acute effects of exposure to space radiation on CNS function and cognitive performance
- (Abstract Only)
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Rabin, B.M., Shukitt Hale, B., Carrihill-Knoll, K.L., Bielinski, D.F., Poulose, S.M., Heroux, N.A., Baxter, C. 2014. Acute effects of exposure to space radiation on CNS function and cognitive performance. Society for Neuroscience Abstracts and Proceedings. 2014. Program #559.13.
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Walnut extracts protect cultured microglia against LPS-induced neurotoxicity via modulation of intracellular calcium concentration
- (Abstract Only)
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Thangthaeng, N., Poulose, S., Fisher, D.R., Shukitt Hale, B. 2014. Walnut extracts protect cultured microglia against LPS-induced neurotoxicity via modulation of intracellular calcium concentration. Society for Neuroscience Abstracts and Proceedings. 2014. Program #144.17.
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Cognition: the new frontier for nuts and berries
- (Review Article)
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Pribis, P., Shukitt Hale, B. 2014. Cognition: the new frontier for nuts and berries. American Journal of Clinical Nutrition. 100(suppl):347S–352S.
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Cerebral blood volume and vasodilation are independently diminished by aging and hypertension: A near infrared spectroscopy study
- (Peer Reviewed Journal)
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Differential protective effects of serum metabolites from young and old walnut-fed rats against stress-induced neurotoxicity in BV-2 microglial cells
- (Abstract Only)
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Shukitt Hale, B., Fisher, D.R., Bielinski, D.F., Poulose, S.M. 2014. Differential protective effects of serum metabolites from young and old walnut-fed rats against stress-induced neurotoxicity in BV-2 microglial cells. [abstract]. American Aging Association. 127:73.
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Effects of dietary blueberry supplementation on older adults
- (Abstract Only)
|
Miller, M.G., Joseph, J.A., Shukitt Hale, B. 2014. Effects of dietary blueberry supplementation on older adults [abstract]. American Aging Association. Paper # 75, p. 53.
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A voyage to Mars: space radiation, aging, and nutrition
- (Review Article)
|
Rabin, B., Shukitt Hale, B. 2014. A voyage to Mars: space radiation, aging, and nutrition. Nutrition and Aging. 2:233-241.
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Blueberry supplementation improves memory in middle-aged mice fed a high-fat diet
- (Peer Reviewed Journal)
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Carey, A.N., Gomes, S.M., Shukitt Hale, B. 2014. Blueberry supplementation improves memory in middle-aged mice fed a high-fat diet. Journal of Agricultural and Food Chemistry. 62:3972-3978.
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Comparison of the effects of partial-or-whole-body exposures to 16O particles on cognitive performance in rats
- (Peer Reviewed Journal)
|
Rabin, B.M., Shukitt Hale, B., Carrihill-Knoll, K.L. 2014. Comparison of the effects of partial-or-whole-body exposures to 16O particles on cognitive performance in rats. Radiation Research. 181:251-257.
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Cognitive effects of partial and whole body exposures to 160 particles
- (Peer Reviewed Journal)
|
Rabin, B., Shukitt Hale, B., Gomes, S., Carrihill-Knoll, K. 2014. Cognitive effects of partial and whole body exposures to 160 particles. Journal of Radiation Research. 55:100-101. DOI: 10.1093/jrr/rrt187.
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Neuronal stress following exposure to 56Fe particles and the effects of antioxidant-rich diets
- (Peer Reviewed Journal)
|
Poulose, S.M., Bielinski, D., Carrihill-Knoll, K., Rabin, B., Shukitt Hale, B. 2014. Neuronal stress following exposure to 56Fe particles and the effects of antioxidant-rich diets. Journal of Radiation Research. 55:73-74. DOI: 10.1093/jrr/rrt155.
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Restoration of stressor-induced calcium dysregulation and autophagy inhibition by polyphenol-rich acai (Euterpe sps.) fruit pulp extracts in rodent brain cells in vitro
- (Peer Reviewed Journal)
|
Poulose, S.M., Fisher, D.R., Bielinski, D., Gomes, S., Rimando, A., Schauss, A., Shukitt Hale, B. 2014. Restoration of stressor-induced calcium dysregulation and autophagy inhibition by polyphenol-rich acai (Euterpe sps.) fruit pulp extracts in rodent brain cells in vitro. Nutrition. 30: 853-862.
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Role of walnuts in maintaining brain health with age
- (Review Article)
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Poulose, S.M., Miller, M.G., Shukitt Hale, B. 2014. Role of walnuts in maintaining brain health with age. Journal of Nutrition. 144 (4 Suppl):561S-566S.
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Tart cherries improve working memory in aged rats
- (Abstract Only)
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Shukitt Hale, B., Miller, M.G., Bielinski, D.F., Poulose, S.M. 2013. Tart cherries improve working memory in aged rats. Society for Neuroscience Abstracts and Proceedings. 2013. Program # 252.03.
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Performance deficit produced by partial body exposures to space radiation
- (Abstract Only)
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Rabin, B.M., Shukitt Hale, B., Carrihill-Knoll, K.L., Gomes, S., Heroux, N. 2013. Performance deficit produced by partial body exposures to space radiation. Society for Neuroscience Abstracts and Proceedings. 2013. Program #445.06.
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Cognitive effects of proton irradiation at differing energy levels
- (Abstract Only)
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Heroux, N., Carrihill-Knoll, K., Rabin, B.M., Shukitt Hale, B. 2013. Cognitive effects of proton irradiation at differing energy levels. Society for Neuroscience Abstracts and Proceedings. 2013. Program # 766.15.
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Dietery acai fruit improves cognition in aged rats
- (Abstract Only)
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Miller, M.G., Fisher, D.R., Carey, A.N., Poulose, S.M., Shukitt Hale, B. 2013. Dietery acai fruit improves cognition in aged rats. Society for Neuroscience Abstracts and Proceedings. 2013. Program # 252.04.
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Dietery walnut alters neurochemical and behavioral functions in young and old rats
- (Abstract Only)
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Poulose, S.M., Fisher, D.R., Miller, M.M., Bielinski, D.F., Ramirez, F., Shukitt Hale, B. 2013. Dietery walnut alters neurochemical and behavioral functions in young and old rats. Society for Neuroscience Abstracts and Proceedings. 2013. Program #252.02.
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Stilbenes and anthocyanins reduce stress signaling in BV-2 mouse microglia
- (Peer Reviewed Journal)
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Carey, A.N., Fisher, D.R., Rimando, A.M., Gomes, S.M., Bielinski, D.F., Shukitt Hale, B. 2013. Stilbenes and anthocyanins reduce stress signaling in BV-2 mouse microglia. Journal of Agricultural and Food Chemistry. 61: 5979-5986.
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Overview of the health properties of blueberries
- (Book / Chapter)
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Elks, C.M., Francis, J., Stull, A.J., Cefalu, W.T., Shukitt Hale, B., Ingram, D.K. 2013. Overview of the health properties of blueberries. In: Skinner, M and Hunter D. editors. Bioactives in Fruit: Health Benefits and Functional Food. Hoboken, NJ. Wiley-Blackwell. p. 251-271.
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Assessment of berry fruit's effects on mobility and cognition in aging
- (Abstract Only)
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Shukitt Hale, B., Miller, M. 2013. Assessment of berry fruit's effects on mobility and cognition in aging. American Aging Association. 42nd Annual Meeting, Pre-conference, Aging and Nutrition Program, Aging: Prevention, Reversal and Slowing. Abstract #2, p. 31.
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Berry effects on cognition and motor function in aging
- (Abstract Only)
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Shukitt Hale, B., Miller, M. 2013. Berry effects on cognition and motor function in aging. Berry Health Benefits Symposium. 2013 Pre-Proceedings, p. 33.
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Effect of berries on cognitive and neurochemical functions
- (Abstract Only)
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Poulose, S.M., Shukitt Hale, B. 2013. Effect of berries on cognitive and neurochemical functions. Meeting Abstract. First International Symposium on Elderberry Proceedings, p. 50.
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Neuronal stress following exposure to 56Fe particles and the effects of antioxidant-rich diets
- (Abstract Only)
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Poulose, S.M., Bielinski, D.F., Carrihill-Knoll, K.L., Rabin, B.M., Shukitt Hale, B. 2013. Neuronal stress following exposure to 56Fe particles and the effects of antioxidant-rich diets. Heavy Ion in Therapy and Space Radiation Symposium Program & Abstracts, Session #NASA-01, p. 49.
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Nutritional interventions protect against age-related deficits in behavior: from animals to humans
- (Abstract Only)
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Shukitt Hale, B., Miller, M.G. 2013. Nutritional interventions protect against age-related deficits in behavior: from animals to humans. Federation of American Societies for Experimental Biology Conference. Abstract 27:862.10.
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Blueberry supplementation improves memory in middle-aged mice consuming a high fat diet
- (Abstract Only)
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Carey, A.N., Shukitt Hale, B. 2013. Blueberry supplementation improves memory in middle-aged mice consuming a high fat diet. Federation of American Societies for Experimental Biology Conference. Abstract 27:1083.5.
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Blueberries and strawberries activate neuronal housekeeping in critical brain regions of stress-induced young rats
- (Abstract Only)
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Poulose, S.M., Bielinski, D.F., Carrihill-Knoll, K., Rabin, B.M., Shukitt Hale, B. 2013. Blueberries and strawberries activate neuronal housekeeping in critical brain regions of stress-induced young rats. Federation of American Societies for Experimental Biology Conference. Abstract 27:637.39.
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Dietary acai fruit improves cognition and mobility in aged rats
- (Abstract Only)
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Miller, M.G., Fisher, D.R., Carey, A.N., Poulose, S.M., Shukitt Hale, B. 2013. Dietary acai fruit improves cognition and mobility in aged rats. Federation of American Societies for Experimental Biology Conference. Abstract 27:1083.3.
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Effects of 17Beta-estradiol on cognitive performance of ovariectomized female rats exposed to 56Fe particles
- (Peer Reviewed Journal)
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Rabin, B., Carrihill-Knoll, K., Long, L., Pitts, S., Shukitt Hale, B. 2013. Effects of 17Beta-estradiol on cognitive performance of ovariectomized female rats exposed to 56Fe particles. Journal of Behavioral and Brain Science. 3:67-73.
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Walnuts and Berries for the Brain
- (Abstract Only)
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Shukitt Hale, B. 2013. Walnuts and Berries for the Brain. The 6th International Congress on Vegetarian Nutrition Progam #2, p.30.
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Coffee, but not caffeine, has positive effects on cognition and psychomotor behavior in aging
- (Peer Reviewed Journal)
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Shukitt Hale, B., Miller, M.G., Chu, Y., Lyle, B., Joseph, J. 2013. Coffee, but not caffeine, has positive effects on cognition and psychomotor behavior in aging. Age. 35:2183-2192.
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Changes in gene expression in the rat hippocampus following exposure to 56 fe particles and protection by berry diets
- (Peer Reviewed Journal)
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Shukitt Hale, B., Lau, F., Cheng, V., Luskin, K., Carey, A., Carrihill-Knoll, K., Rabin, B., Joseph, J.A. 2013. Changes in gene expression in the rat hippocampus following exposure to 56 fe particles and protection by berry diets. Central Nervous System Agents in Medicinal Chemistry. 13:36-42.
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Functional role of walnuts and acai fruits on brain health
- (Book / Chapter)
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Poulose, S.M., Shukitt Hale, B. 2013. Functional role of walnuts and acai fruits on brain health. IN: Patil, B.S., Jayaprakasha, G.K., Roa, C.O., Mahattanatawee, K. Eds. Tropical and Subtropical Fruits. American Chemical Society Publications, Washington DC. p.171-187.
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Berry fruit and nuts: their role in reducing oxidative stress and inflammation in the aging brain
- (Book / Chapter)
|
Miller, M.G., Shukitt Hale, B., Joseph, J.A. 2012. Berry fruit and nuts: their role in reducing oxidative stress and inflammation in the aging brain. In: Carkeet, C., Grann, K., Randolph, R. K., Venzon, D.S., Izzy, S. Phytochemicals: Health Promotion and Therapeutic Potential. CRC Press. p. 181-204.
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The effects of blueberry supplementation in middle aged mice consuming a high fat diet
- (Abstract Only)
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Carey, A.N., Shukitt Hale, B. 2012. The effects of blueberry supplementation in middle aged mice consuming a high fat diet [abstract]. Society for Neuroscience Abstracts and Proceedings. Paper No. 865:01.
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Serum metabolites from walnut-fed aged rats attenuate stress-induced neurotoxicity in brain cells in vitro
- (Abstract Only)
|
Poulose, S.M., Fisher, D.R., Bielinski, D., Shukitt Hale, B. 2012. Serum metabolites from walnut-fed aged rats attenuate stress-induced neurotoxicity in brain cells in vitro [abstract]. Society for Neuroscience Abstracts and Proceedings. Paper No. 865:02.
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Sex differences in operant responding and survivability following exposure to space radiation
- (Abstract Only)
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Carrihill-Knoll, K., Rabin, B., Shukitt Hale, B. 2012. Sex differences in operant responding and survivability following exposure to space radiation [abstract]. Society for Neuroscience Abstracts and Proceedings. 915:14.
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Acai fruit improves motor and cognitive function in aged rats
- (Abstract Only)
|
Shukitt Hale, B., Carey, A.N., Miller, M., Poulose, S.M. 2012. Acai fruit improves motor and cognitive function in aged rats [abstract]. Society for Neuroscience Abstracts and Proceedings. Paper No. 865:04.
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Human cognition and mobility in aging: a model for berry fruit interventions
- (Abstract Only)
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Miller, M., Shukitt Hale, B. 2012. Human cognition and mobility in aging: a model for berry fruit interventions [abstract]. Society for Neuroscience Abstracts and Proceedings. Paper No. 865:03.
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Blueberries and neuronal aging
- (Review Article)
|
Shukitt Hale, B. 2012. Blueberries and neuronal aging. Gerontology Journal. 58:518-523.
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Walnut diet reduces accumulation of polyubiquitinated proteins and inflammation in the brain of aged rats
- (Peer Reviewed Journal)
|
Poulose, S., Bielinski, D., Shukitt Hale, B. 2012. Walnut diet reduces accumulation of polyubiquitinated proteins and inflammation in the brain of aged rats. Journal of Nutritional Biochemistry. DOI: 10.1016/j.jnutbio.2012.06.09.
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Improving brain signaling in aging: could berries be the answer?
- (Popular Publication)
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Poulose, S.M., Carey, A.N., Shukitt Hale, B. 2012. Improving brain signaling in aging: could berries be the answer?. Popular Publication. 8:887-889.
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The ability of walnut extract and fatty acids to protect against the deleterious effects of oxidative stress and inflammation in hippocampal cells
- (Peer Reviewed Journal)
|
Carey, A.N., Fisher, D.R., Joseph, J.J., Shukitt Hale, B. 2013. The ability of walnut extract and fatty acids to protect against the deleterious effects of oxidative stress and inflammation in hippocampal cells. Nutritional Neuroscience. 16(1):13-20.
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The beneficial effects of tree nuts on the aging brain
- (Review Article)
|
Carey, A.N., Poulose, S.M., Shukitt Hale, B. 2012. The beneficial effects of tree nuts on the aging brain. Nutrition and Aging. 1:55-67.
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Berry fruit enhances beneficial signaling in brain
- (Review Article)
|
Miller, M., Shukitt Hale, B. 2012. Berry fruit enhances beneficial signaling in brain. Journal of Agricultural and Food Chemistry. 60:5709-5715.
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Anthocyanin-rich acai (Euterpe oleracea mart.) fruit pulp fractions attenuate inflammatory stress signaling in mouse brain BV-2 microglial cells
- (Peer Reviewed Journal)
|
Poulose, S.M., Fisher, D.R., Larson, J., Bielinski, D.F., Rimando, A.M., Carey, A.N., Schauss, A.G., Shukitt Hale, B. 2012. Anthocyanin-rich acai (Euterpe oleracea mart.) fruit pulp fractions attenuate inflammatory stress signaling in mouse brain BV-2 microglial cells. Journal of Agricultural and Food Chemistry. 60:1084-1093.
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Dietary supplementation with coffee improves motor and cognitive performance in aged rats
- (Abstract Only)
|
Carey, A.N., Shukitt Hale, B. 2011. Dietary supplementation with coffee improves motor and cognitive performance in aged rats [abstract]. Gerontological Society of America. Program No. 955-17.
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Effects of flavonoids on cognitive performance
- (Book / Chapter)
|
Poulose, S.M., Shukitt Hale, B. 2012. Effects of flavonoids on cognitive performance. In: Spencer, J., Crozier, A., editors. Flavonoids and Related Compounds: Bioavailability and Function. United Kingdom: Taylor and Francis Group LLC, CRC Press. p. 393-411.
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The behavioral and neuronal signaling benefits of polyphenols
- (Abstract Only)
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Shukitt Hale, B. 2011. The behavioral and neuronal signaling benefits of polyphenols. 5th International Conference on Polyphenols and Health [abstract}. Abstract No. 068.
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Coffee and Alzheimer’s disease - animal & cellular evidences
- (Book / Chapter)
|
Miller, M.G., Shukitt Hale, B. 2012. Coffee and Alzheimer’s disease - animal & cellular evidences. In: Chu, YiFang, editor. Coffee: Emerging Health Effects and Disease Prevention. New York, NY: John Wiley. p. 77-96.
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Exposure to O-16 particle irradiation causes age-like decrements in rats through increased oxidative stress, inflammation and loss of autophagy
- (Peer Reviewed Journal)
|
Poulose, S.M., Bielinski, D., Carrihill-Knoll, K., Rabin, B.M., Shukitt Hale, B. 2011. Exposure to O-16 particle irradiation causes age-like decrements in rats through increased oxidative stress, inflammation and loss of autophagy.Radiation Research. 176:761-769.
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Low-dose pterostilbene but not resveratrol is a potent neuromodulator in aging and Alzheimer’s Disease
- (Peer Reviewed Journal)
|
Chang, J., Rimando, A.M., Pallas, M., Camins, A., Porquet, D., Reeves, J., Shukitt Hale, B., Smith, M.A., Joseph, J.A., Casadesus, G. 2011. Low-dose pterostilbene but not resveratrol is a potent neuromodulator in aging and Alzheimer’s Disease. Neurobiology of Aging. 33:2062-2071.
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A blueberry enriched diet attenuates nephropathy in a rat model of hypertension via reduction in oxidative stress
- (Peer Reviewed Journal)
|
Elks, C.M., Mariappan, N., Shukitt Hale, B., Joseph, J.A., Ingram, D.K., Francis, J. 2011. A blueberry enriched diet attenuates nephropathy in a rat model of hypertension via reduction in oxidative stress. PLoS One. 6(9)e24028.
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Food for thought: what Jim Joseph taught me about aging and nutrition
- (Abstract Only)
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Operant responding following exposure to HZE particles and its relationship to particle energy and LET
- (Peer Reviewed Journal)
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Rabin, B.M., Carrihill-Knoll, K., Shukitt Hale, B. 2011. Operant responding following exposure to HZE particles and its relationship to particle energy and LET. Advances in Space Research. 48:370-377.
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Interaction between age of irradiation and age of testing in the disruption of operant performance using a ground-based model for exposure to cosmic rays
- (Peer Reviewed Journal)
|
Rabin, B.M., Joseph, J.A., Shukitt Hale, B., Carrihill-Knoll, K. 2012. Interaction between age of irradiation and age of testing in the disruption of operant performance using a ground-based model for exposure to cosmic rays. American Aging Association. 34:121-131.
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Short-term nutritional folate deficiency in rats has a greater effect on choline and acetylcholine metabolism in the peripheral nervous system than in the brain, and this effect escalates with age
- (Peer Reviewed Journal)
|
Crivello, N., Blusztajn, J., Joseph, J.A., Shukitt Hale, B., Smith, D. 2010. Short-term nutritional folate deficiency in rats has a greater effect on choline and acetylcholine metabolism in the peripheral nervous system than in the brain, and this effect escalates with age. Nutrition Research. 30(10):722-730.
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Differential protection among fractionated blueberry polyphenolic families against DA-, ABeta 42 and LPS-induced decrements in Ca2+ buffering in primary hippocampal cells
- (Peer Reviewed Journal)
|
Joseph, J.A., Shukitt Hale, B., Brewer, G.J., Weikel, K.A., Kalt, W., Fisher, D.R. 2010. Differential protection among fractionated blueberry polyphenolic families against DA-, ABeta 42 and LPS-induced decrements in Ca2+ buffering in primary hippocampal cells. Journal of Agriculture and Food Chemistry. 58:8196-8204.
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Short-term blueberry-enriched antioxidant diet prevents and reverses object recognition memory loss in aged rats
- (Peer Reviewed Journal)
|
Malin, D.H., Lee, D.R., Goyarzu, P., Chang, Y., Ennis, L.J., Beckett, E., Shukitt Hale, B., Joseph, J.A. 2011. Short-term blueberry-enriched antioxidant diet prevents and reverses object recognition memory loss in aged rats. Nutrition. 27:338-342.
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Blueberry supplementation improves memory in older adults
- (Peer Reviewed Journal)
|
Krikorian, R., Shidler, M., Nash, T., Kalt, W., Vinqvist-Tymchuk, M., Shukitt Hale, B., Joseph, J.A. 2010. Blueberry supplementation improves memory in older adults. Journal of Agricultural and Food Chemistry. 58:3996-4000.
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Survival and cardioprotective benefits of long-term blueberry enriched diet in dilated cardiomyopathy following myocardial infarction in rats
- (Peer Reviewed Journal)
|
Ismayil, A., Spangler, E., Shukitt Hale, B., Joseph, J.A., Ingram, D., Talan, M. 2009. Survival and cardioprotective benefits of long-term blueberry enriched diet in dilated cardiomyopathy following myocardial infarction in rats. PLoS One. 4(11):e7975.
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Concord Grape Juice Supplementation Improves Memory Function In Older Adults with Mild Cognitive Impairment
- (Peer Reviewed Journal)
|
Krikorian, R., Nash, T.A., Shidler, M.D., Shukitt Hale, B., Joseph, J.A. 2009. Concord Grape Juice Supplementation Improves Memory Function In Older Adults with Mild Cognitive Impairment. British Journal of Nutrition. 103:730-734.
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Dietary polyunsaturated fatty acids improve cholinergic transmission in the aged brain
- (Peer Reviewed Journal)
|
Willis, L., Shukitt Hale, B., Joseph, J.A. 2009. Dietary polyunsaturated fatty acids improve cholinergic transmission in the aged brain. Genes and Nutrition. 4:309-314.
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Fruits, Nuts, and Brain Aging: Nutritional Interventions Targeting Age-Related Neuronal and Behavioral Deficits
- (Book / Chapter)
|
Joseph, J.A., Shukitt Hale, B., Willis, L. 2009. Fruits, Nuts, and Brain Aging: Nutritional Interventions Targeting Age-Related Neuronal and Behavioral Deficits. In: Packer, L., Sies, H., Eggersdorfer, M., and Cadenas, E., editors. Micronutrients and Brain Health. Boca Raton, FL: CRC Press. p. 179-188.
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Blueberry-enriched diet protects rat heart from ischemic damage
- (Peer Reviewed Journal)
|
Ahmet, I., Spangler, E., Shukitt Hale, B., Juhaszova, M., Sollott, S.J., Joseph, J.A., Ingram, D.K., Talan, M. 2009. Blueberry-enriched diet protects rat heart from ischemic damage. PLoS One. 4(5934):1-10.
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Grape juice, berries and walnuts affect brain aging and behavior
- (Review Article)
|
Joseph, J.A., Shukitt Hale, B., Willis, L. 2009. Grape juice, berries and walnuts affect brain aging and behavior. Journal of Nutrition. 139:1813S-1817S.
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Mitigation of oxidative stress and inflammatory signaling by fruit and walnut polyphenols: implications for cognitive aging
- (Book / Chapter)
|
Joseph, J.J., Shukitt Hale, B., Willis, L. 2010. Mitigation of oxidative stress and inflammatory signaling by fruit and walnut polyphenols: implications for cognitive aging. In: Santos-Buelga, C., Escribano-Bailon, M., Lattanzio V., editors. Recent Advances in Polyphenol Research. Volume 2. Oxford, England: Blackwell Publishing Ltd. 2:283-293.
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Modulation of cognition and behavior in aged animals: role of antioxidant and essential fatty acid rich plant foods
- (Review Article)
|
Willis, L., Shukitt Hale, B., Joseph, J.A. 2009. Modulation of cognition and behavior in aged animals: role of antioxidant and essential fatty acid rich plant foods. American Journal of Clinical Nutrition. 89:1602S-1606S.
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Effects of Blackberries on Motor and Cognitive Function in Aged Rats
- (Peer Reviewed Journal)
|
Shukitt Hale, B., Cheng, V., Joseph, J.A. 2009. Effects of Blackberries on Motor and Cognitive Function in Aged Rats. Nutritional Neuroscience.12:135-140.
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Effects of heavy particle irradiation on diet on object recognition memory in rats
- (Peer Reviewed Journal)
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Rabin, B.M., Carrihill-Knoll, K., Hinchman, M., Shukitt Hale, B., Joseph, J.A., Foster, B.C. 2009. Effects of heavy particle irradiation on diet on object recognition memory in rats. Advances in Space Research. 43:1193-1199.
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Plum Juice, but Not Dried Plum Powder, is Effective in Mitigating Cognitive Deficits in Aged Rats
- (Peer Reviewed Journal)
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Shukitt Hale, B., Kalt, W., Carey, A., Vinqvist-Tymchuk, M., Mcdonald, J., Joseph, J.A. 2009. Plum Juice, but Not Dried Plum Powder, is Effective in Mitigating Cognitive Deficits in Aged Rats. Nutrition.25:567-573.
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Recent Advances in Berry Supplementation and Age-Related Cognitive Decline
- (Review Article)
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Willis, L., Shukitt Hale, B., Joseph, J.A. Recent Advances in Berry Supplementation and Age-Related Cognitive Decline. Current Opinion in Clinical Nutrition and Metabolic Care. 2009. 12:91-94.
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Cellular and Behavioral Effects of Stilbene Resveratrol Analogs: Implications for Reducing the Deleterious Effects of Aging
- (Peer Reviewed Journal)
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Joseph, J.A., Fisher, D.R., Cheng, V., Rimando, A.M., Shukitt Hale, B. 2008. Cellular and Behavioral Effects of Stilbene Resveratrol Analogs: Implications for Reducing the Deleterious Effects of Aging. Journal of Agriculture and Food Chemistry.56(22)10544-10551.
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Cognitive impairment in folate-deficient rats corresponds to depleted brain phosphatidylcholine and is prevented by methionine without lowering homocysteine
- (Peer Reviewed Journal)
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Troen, A.M., Chao, W., Crivello, N.A., Shukitt Hale, B., Smith, D., Selhub, J., Rosenberg, I. 2008. Cognitive impairment in folate-deficient rats corresponds to depleted brain phosphatidylcholine and is prevented by methionine without lowering homocysteine. Journal of Nutrition. 138(12):2502-2509.
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Dose-Dependent Effects of Walnuts on Motor and Cognitive Function in Aged Rats
- (Peer Reviewed Journal)
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Willis, L., Shukitt Hale, B., Cheng, V., Joseph, J.A. 2009. Dose-Dependent Effects of Walnuts on Motor and Cognitive Function in Aged Rats. British Journal of Nutrition. 101:1140-1144.
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B-vitamin deficiency causes hyperhomocysteinemia and vascular cognitive impairment in mice
- (Peer Reviewed Journal)
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Troen, A.M., Shea-Budgell, M., Shukitt Hale, B., Smith, D., Selhub, J., Rosenberg, I. 2008. B-vitamin deficiency causes hyperhomocysteinemia and vascular cognitive impairment in mice. Proceedings of the National Academy of Sciences. 105(34):12474-12479.
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Effects of Berry Fruits on Neurocognitive Deficits Produced by Exposure to Space Radiation
- (Book / Chapter)
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Rabin, B.M., Joseph, J.A., Shukitt Hale, B. 2008. Effects of Berry Fruits on Neurocognitive Deficits Produced by Exposure to Space Radiation. In: Arora, R. Herbal Radiomodulators Applications in Medicine, Homeland Defence and Space. Wallingford, UK: Institute of Nuclear Medicine and Allied Sciences. p.151-161.
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Blueberry polyphenols attenuate kainic acid-induced decrements in cognition and alter inflammatory gene expression in rat hippocampus
- (Peer Reviewed Journal)
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Shukitt Hale, B., Lau, F.C., Carey, A.N., Galli, R.L., Spangler, E.L., Ingram, D.K., Joseph, J.A. 2008. Blueberry polyphenols attenuate kainic acid-induced decrements in cognition and alter inflammatory gene expression in rat hippocampus. Nutritional Neuroscience. 11(4):172-182.
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"Brainberries" and Aging
- (Other)
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Joseph, J.A., Shukitt Hale, B. 2008. "Brainberries" and Aging. Clinical Nutrition Insight.34:1-4.
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Berry Fruit Supplementation in the Aging Brain
- (Review Article)
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Shukitt Hale, B., Lau, F.C., Joseph, J.A. 2008. Berry Fruit Supplementation in the Aging Brain. Journal of Agriculture and Food Chemistry. 56:636-641.
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Polyphenols and Polyunsaturate Fatty Acids: The Pollyanna's of Age-Related Cognitive Decline, Neurodegenerative Disease
- (Book / Chapter)
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Joseph, J.A., Smith, M.A., Perry, G., Shukitt Hale, B. 2008. Polyphenols and Polyunsaturate Fatty Acids: The Pollyanna's of Age-Related Cognitive Decline, Neurodegenerative Disease. In Coulston, A.M. and Boushey, C.J., editors. Nutrition in the Prevention and Treatment of Disease. 2nd edition. San Diego: Elsevier. p. 269-287.
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Blueberries and Human Health: A Review of Current Research
- (Peer Reviewed Journal)
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Kalt, W., Joseph, J.A., Shukitt Hale, B. 2007. Blueberries and Human Health: A Review of Current Research. Journal of American Pomological Society. 61:151-160.
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Aging modifies brain region-specific vulnerability to experimental oxidative stress induced by low dose hydrogen peroxide
- (Peer Reviewed Journal)
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Denissova, N., Rosenberg, I., Shukitt Hale, B., Bielinski, D., Dallal, G., Joseph, J.A. 2007. Aging modifies brain region-specific vulnerability to experimental oxidative stress induced by low dose hydrogen peroxide. American Aging Association. 29:191-203.
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Dietary modulation of the effects of exposure to 56FE particles
- (Peer Reviewed Journal)
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Rabin, B.M., Joseph, J.A., Shukitt Hale, B., Carey, A.N. 2007. Dietary modulation of the effects of exposure to 56FE particles. Advances in Space Research. 40(4):576-580.
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A blueberry-enriched diet provides cellular protection against oxidative stress and attenuates a kainate-induced learning impairment in rats
- (Peer Reviewed Journal)
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Duffy, K.B., Spangler, E.L., Devan, B.D., Guo, Z., Bowker, J.L., Janas, A.M., Hagapanos, A., Minor, R.K., Decabo, R., Mouton, P.R., Shukitt Hale, B., Joseph, J.A., Ingram, D.K. 2008. A blueberry-enriched diet provides cellular protection against oxidative stress and attenuates a kainate-induced learning impairment in rats. Neurobiology of Aging. 29:1680-1689.
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Amphetamine-Induced Taste Aversion Learning in Young and Old F-344 Rats Following Exposure to 56Fe Particles
- (Peer Reviewed Journal)
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Carrihill-Knoll, K.L., Rabin, B.M., Shukitt Hale, B., Joseph, J.A., Carey, A. 2007. Amphetamine-Induced Taste Aversion Learning in Young and Old F-344 Rats Following Exposure to 56Fe Particles. Pharmacology, Biochemistry and Behavior. 29(2):69-76.
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Fruit Polyphenols and their effects on Neuronal Signaling and Behavior in Senescence.
- (Book / Chapter)
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Joseph, J.A., Shukitt Hale, B., Lau, F.C. 2007. Fruit Polyphenols and their effects on Neuronal Signaling and Behavior in Senescence. Annals of the New York Academy of Sciences. 1100:470-485.
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Interaction between age and exposure to 56Fe particles on behavior and neurochemistry
- (Peer Reviewed Journal)
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Carey, A.N., Shukitt Hale, B., Rabin, B.M., Joseph, J.A. 2007. Interaction between age and exposure to 56Fe particles on behavior and neurochemistry. Advances in Space Research. 39:987-993.
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Elevated plus-maze performance of Fischer-344 rats as a function of age and of exposure to 56Fe particles
- (Peer Reviewed Journal)
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Rabin, B.M., Carrihill-Knoll, K.L., Carey, A.N., Shukitt Hale, B., Joseph, J.A., Foster, B.C. 2007. Elevated plus-maze performance of Fischer-344 rats as a function of age and of exposure to 56Fe particles. Advances in Space Research. 39:981-986.
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Exposure to 56Fe irradiation accelerates normal brain aging and produces deficits in spatial learning and memory
- (Review Article)
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Shukitt Hale, B., Casadesus, G., Carey, A.N., Rabin, B.M., Joseph, J.A. 2007. Exposure to 56Fe irradiation accelerates normal brain aging and produces deficits in spatial learning and memory. Advances in Space Research. 39:1087-1092.
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Nutritional Intervention in Brain Aging: Reducing the Effects of Inflammation and Oxidative Stress
- (Book / Chapter)
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Lau, F.C., Shukitt Hale, B., Joseph, J.A. 2007. Nutritional Intervention in Brain Aging: Reducing the Effects of Inflammation and Oxidative Stress. Inflammation in the Pathogenesis of Chronic Diseases:The COX-2 controversy. Subcellular Biochemistry. Volume 42. New York, NY:Springer Publication. p.299-318.
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BENEFICIAL EFFECTS OF FRUIT EXTRACTS ON NEURONAL FUNCTION AND BEHAVIOR IN A RODENT MODEL OF ACCELERATED AGING
- (Peer Reviewed Journal)
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Shukitt Hale, B., Carey, A.N., Jenkins, D., Rabin, B.M., Joseph, J.A. 2007. Beneficial effects of fruit extracts on neuronal function and behavior in a rodent model of accelerated aging. Neurobiology of Aging.28:1187-1194.
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Beneficial effects of berryfruit polyphenols on neuronal behavioral aging
- (Review Article)
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Lau, F.C., Shukitt Hale, B., Joseph, J.A. 2006. Beneficial effects of berryfruit polyphenols on neuronal behavioral aging. Journal of the Science of Food and Agriculture.86:2251-2255.
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DIETARY SUPPLEMENTATION WITH BLUEBERRY EXTRACT IMPROVES SURVIVAL OF TRANSPLANTED DOPAMINE NEURONS
- (Peer Reviewed Journal)
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Mcguire, S.O., Sortwell, C.E., Shukitt Hale, B., Joseph, J.A., Hejna, M.J., Collier, T.J. 2006. Dietary supplementation with blueberry extract improves survival of transplanted dopamine neurons. Nutritional Neuroscience. 9(5/6): 251-258.
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BHT blocks NfkB activation and Ethanol-Induced Brain Damage
- (Peer Reviewed Journal)
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Crews, F.T., Nixon, K., Kim, D., Joseph, J.A., Shukitt Hale, B., Qin, L., Zou, J. 2006. Bht blocks nfkb activation and ethanol-induced brain damage. Alcoholism: Clinical and Experimental.30(11):1938-1949.
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A blueberry-enriched antioxidant diet reduces an age-related deficit in one trial per day discriminative reward learning
- (Abstract Only)
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Goyarzu, P., Malin, D.H., Moon, W.D., Moy, E., Moy, D., Jennings, R., Lippold, S., Shukitt Hale, B., Joseph, J.A. 2006. A blueberry-enriched antioxidant diet reduces an age-related deficit in one trial per day discriminative reward learning. Society for Neuroscience Abstracts and Proceedings.
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The cognitive impact of nutritional homocysteinemia in apolipoprotein-E deficient mice
- (Peer Reviewed Journal)
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Troen, A.M., Shukitt Hale, B., Chao, W., Alburquerque, B., Smith, D.E., Selhub, J., Rosenberg, I. 2006. The cognitive impact of nutritional homocysteinemia in apolipoprotein-E deficient mice. Journal of Alzheimer's Disease. 9(4): 381-92.
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Blueberries and the Aging Brain: Beyond Antioxidants
- (Trade Journal)
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Mark, D.A., Shukitt Hale, B., Joseph, J.A. 2006. Blueberries and the Aging Brain: Beyond Antioxidants. The Food Journal.49(2):50-55.
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BLUEBERRY POLYPHENOLS INCREASE CAENORHABDITIS ELEGANS SURVIVAL DURING AGING AND THERMAL STRESS
- (Peer Reviewed Journal)
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Wilson, M.A., Shukitt Hale, B., Kalt, W., Ingram, D.K., Joseph, J.A., Wolkow, C.A. 2006. Blueberry polyphenols increase caenorhabditis elegans survival during aging and thermal stress. Aging Cell. (5):55-68
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AGE RELATED NEURONAL AND BEHAVIORAL DEFICITS ARE IMPROVED BY POLYPHENOL RICH BLUEBERRY SUPPLEMENTATION
- (Book / Chapter)
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Lau, F.C., Shukitt Hale, B., Joseph, J.A. 2005. Age related neuronal and behavioral deficits are improved by polyphenol rich blueberry supplementation. CRC Press. p. 499.
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THE BENEFICIAL EFFECTS OF FRUIT POLYPHENOLS ON BRAIN AGING
- (Review Article)
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Lau, F.C., Shukitt Hale, B., Joseph, J.A. 2005. The beneficial effects of fruit polyphenols on brain aging. Neurobiology of Aging. 26S:S128-S132.
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EFFECTS OF CONCORD GRAPE JUICE ON COGNITIVE AND MOTOR DEFICITS IN AGING
- (Peer Reviewed Journal)
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Shukitt Hale, B., Carey, A.N., Simon, L.E., Mark, D.A., Joseph, J.A. 2006. Effects of Concord Grape Juice on Cognitive and Motor Deficits in Aging. Nutrition. 22:295-302.
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EFFECTS OF AGE AND EXPOSURE TO GOUND-BASED MODELS OF COSMIC RAYS ON ELEVATED PLUS MAZE PERFORMANCE IN RATS
- (Abstract Only)
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Carrihill-Knoll, K.L., Maloney, B.K., Rabin, B.M., Shukitt Hale, B., Joseph, J.A., Carey, A.N. 2005. Effects of age and exposure to gound-based models of cosmic rays on elevated plus maze performance in rats. Society for Neuroscience Abstracts and Proceedings. Abstract No. 656.10.
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DIFFERENTIAL EFFECTS OF BLUEBERRY EXTRACT PREPARATIONS ON COGNTIVE AND MOTOR FUNCTION IN AGING: THE ROLE OF PHENOLICS
- (Abstract Only)
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Shukitt Hale, B., Carey, A.N., Kalt, W., Mcdonald, J., Vinqvist, M., Joseph, J.A. 2005. Differential effects of blueberry extract preparations on cogntive and motor function in aging: the role of phenolics. Society for Neuroscience Abstracts and Proceedings. Abstract No. 93.5.
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OXIDATIVE STRESS AND INFLAMMATION IN BRAIN AGING: NUTRITIONAL CONSIDERATIONS
- (Review Article)
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Joseph, J.A., Shukitt Hale, B., Casadesus, G., Fisher, D.R. 2005. Oxidative stress and inflammation in brain aging: nutritional considerations. Neurochemical Research. Volume(30):927-935
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THE EFFECTS OF ANTIOXIDANTS IN THE SENESCENT AUDITORY CORTEX
- (Peer Reviewed Journal)
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De Rivera, C., Shukitt Hale, B., Joseph, J.A., Mendelson, J.R. 2006. The effects of antioxidants in the senescent auditory cortex. Neurobiology of Aging. 27(7):1035-1044.
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DIETARY SUPPLEMENTATION WITH FRUIT POLYPHENOLICS AMELIORATES AGE-RELATED DEFICITS IN BEHAVIOR AND NEURONAL MARKERS OF INFLAMMATION AND OXIDATIVE STRESS
- (Peer Reviewed Journal)
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Shukitt Hale, B., Meterko, V., Carey, A.N., Bielinski, D., Mcguie, T., Galli, R., Joseph, J.A. 2005. Dietary supplementation with fruit polyphenolics ameliorates age-related deficits in behavior and neuronal markers of inflammation and oxidative stress. Age. 2005, 27, 49-57.
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REVERSING THE DELETERIOUS EFFECTS OF AGING ON NEURONAL COMMUNICATION AND BEHAVIOR: THE BENEFICIAL PROPERTIES OF FRUIT POLYPHENOLICS
- (Peer Reviewed Journal)
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Joseph, J.A., Shukitt Hale, B., Casadesus, G. 2005. Reversing the deleterious effects of aging on neuronal communication and behavior: the beneficial properties of fruit polyphenolics. American Journal of Clinical Nutrition 2005, 81 (Suppl.) 313S-316S
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EFFECT OF DIET ON THE DISRUPTION OF OPERANT RESPONDING AT DIFFERENT AGES FOLLOWING EXPOSURE TO FE56 PARTICLES
- (Peer Reviewed Journal)
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Rabin, B.M., Carrihill-Knoll, K.L., Carey, A.N., Shukitt Hale, B., Joseph, J.A. 2005. Effect of diet on the disruption of operant responding at different ages following exposure to fe56 particles. Age. 205, 27, 69-73.
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DIET AS A FACTOR IN BEHAVIORAL RADIATION PROTECTION FOLLOWING EXPOSURE TO HEAVY PARTICLES
- (Peer Reviewed Journal)
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Rabin, B.M., Shukitt Hale, B., Joseph, J.A., Tood, P. 2005. Diet as a factor in behavioral radiation protection following exposure to heavy particles. American Society for Gravitation and Space Biology 18(2)June 2005.
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ANTHOCYANINS IN AGED BLUEBERRY-FED RATS ARE FOUND CENTRALLY AND MAY ENHANCE MEMORY
- (Peer Reviewed Journal)
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Andres-Lacueva, C., Shukitt Hale, B., Galli, R.L., Jaurengui, O., Lamuela-Raventos, R.M., Joseph, J.A. 2005. Anthocyanins in aged blueberry-fed rats are found centrally and may enhance memory. Nutritional Neuroscience, April 2005:8(2): 111-120.
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BLUEBERRY SUPPLEMENTED DIET REVERSES AGE-RELATED DECLINE IN HIPPOCAMPAL HSP70 NEUROPROTECTION
- (Peer Reviewed Journal)
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Galli, R.L., Bielinski, D.F., Szprengiel, A., Shukitt Hale, B., Joseph, J.A. 2006. Blueberry supplemented diet reverses age-related decline in hippocampal hsp70 neuroprotection. Neurobiology of Aging 27 (2006)344-350.
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EFFECTS OF AGE AND DIET ON THE HEAVY PARTICLE-INDUCED DISRUPTIONS OF OPERANT RESPONDING PRODUCED BY A GROUND-BASED MODEL FOR EXPOSURE TO COSMIC RAYS
- (Peer Reviewed Journal)
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Rabin, B.M., Joseph, J.A., Shukitt Hale, B., 2005. Effects of age and diet on the heavy particle-induced disruptions of operant responding produced by a ground-based model for exposure to cosmic rays. Brain Research 1036(2005) 122-129.
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A LONGITUDINAL STUDY OF OPERANT RESPONDING IN RATS IRRADIATED AT TWO MONTHS OF AGE
- (Peer Reviewed Journal)
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Rabin, B.M., Joseph, J.A., Shukitt Hale, B. 2005. A longitudinal study of operant responding in rats irradiated at two months of age. Radiation Research. 164:552-555.
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MODULATION OF HIPPOCAMPAL PLASTICITY AND COGNITIVE BEHAVIOR BY SHORT-TERM BLUEBERRY SUPPLEMENTATION IN AGED RATS
- (Peer Reviewed Journal)
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Casadesus, G., Shukitt Hale, B., Stellwagen, H.M., Zhu, X., Lee, H., Smith, M.A., Joseph, J.A. 2004. Modulation of hippocampal plasticity and cognitive behavior by short-term blueberry supplementation in aged rats. Nutritional Neuroscience, Volume 7 Number 5/6 (October/December 2004), pp.309-316
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HIPPOCAMPAL NEUROGENESIS AND PSA-NCAM EXPRESSION FOLLOWING EXPOSURE TO 56FE PARTICLES MIMICS THAT SEEN DURING AGING
- (Peer Reviewed Journal)
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Casadesus, G., Stellwagen, H.M., Shukitt Hale, B., Rabin, B.M., Joseph, J.A. 2005. Hippocampal neurogenesis and psa-ncam expression following exposure to 56fe particles mimics that seen during aging. Gerontology Journal. 40 249-254
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FLAVONOIDS AND THE BRAIN: INTERACTIONS AT THE BLOOD BRAIN BARRIER AND THEIR PHYSIOLOGICAL EFFECT ON THE CNS
- (Review Article)
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Youdim, K.A., Shukitt Hale, B., Joseph, J.A. 2004. Flavonoids and the brain: interactions at the blood brain barrier and their physiological effect on the cns. Free Radical Biology and Medicine, VOL 37, NO11 PP. 1683-1693.
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THE BENEFICIAL EFFECTS OF FRUIT AND VEGETABLE SUPPLEMENTATION ON NEURONAL SIGNALING AND BEHAVIOR IN AGING: BEYOND ANTIOXIDANTS
- (Book / Chapter)
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Joseph, J.A., Shukitt Hale, B., Casadesus, G. 2006. The beneficial effects of fruit and vegetable supplementation on neuronal signaling and behavior in aging: beyond antioxidants. In: Stagg, J.J. and Foster, J. G. Editors. Nutrients, Stress and Medical Disorders. Totowa, MJ:Humana Press. p. 67-82
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FRUIT POLYPHENOLS PREVENT INFLAMMATORY MEDIATED DECREMENTS IN COGNITION
- (Proceedings)
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Shukitt Hale, B., Carey, A.N., Belinski, D., Lau, F.C., Galli, R.L., Spangler, E.L., Ingram, D.K., Joseph, J.A. 2004. Fruit polyphenols prevent inflammatory mediated decrements in cognition. Soc. Neurosci. Abs. 2004, 30,565.5.
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NUTRITION AND COMMUNICATION IN THE AGED BRAIN: CAN YOU HEAR US NOW?
- (Peer Reviewed Journal)
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Joseph, J.A., Shukitt Hale, B., Smith, M. 2004. Nutrition and communication in the aged brain: can you hear us now? Acarology International Congress Proceedings.
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THE BENEFICIAL PROPERTIES OF FRUIT POLYPHENOLS ON NEURONAL COMMUNICATION AND BEHAVIOR IN AGING
- (Book / Chapter)
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Joseph, J.A., Shukitt Hale, B., Casadesus, G. 2004. The beneficial properties of fruit polyphenols on neuronal communication and behavior in aging. In: Stagg, J.J., Foster, J.G. editors. Medicinal and Aromatic Plants: Production, Business and Applications. West Virginia: Mountain State University Press. p.18-30.
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DIETARY SUPPLEMENTATION WITH BLUEBERRY EXTRACT DECREASES INFLAMMATION AFTER BRAIN INJURY IN RATS: IMPLICATIONS FOR NEURAL TRANSPLANTATION
- (Proceedings)
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Mcguire, S.O., Hejna, M.J., Shukitt Hale, B., Joseph, J.A., Collier, T.J., Lorens, S.A. Dietary supplementation with blueberry extract decreases inflammation after brain injury in rats: implications for neural transplantation. 2004 Society for Neuroscience Abstracts and Proceedings.
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BLUEBERRY SUPPLEMENTED DIET: EFFECTS ON OBJECT RECOGNITION MEMORY & NUCLEAR FACTOR KAPPA B LEVELS IN AGED RATS
- (Peer Reviewed Journal)
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Goyarzu, P., Malin, D.H., Lau, F.C., Taglialatela, G., Moon, W.D., Jennings, R., Moy, E., Moy, D., Lippold, S., Shukitt Hale, B., Joseph, J.A. 2004. Blueberry supplemented diet: effects on object recognition memory & nuclear factor kappa b levels in aged rats. Nutritional Neuroscience. 7(2):75-83.
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FRUIT POLYPHENOLICS AND SIGNALING IN THE AGED BRAIN:ALTERING MOTOR AND COGNITIVE DEFICITS
- (Book / Chapter)
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Joseph, J.A., Shukitt Hale, B. 2004. Fruit polyphenolics and signaling in the aged brain:altering motor and cognitive deficits. In: Ozben, T., Chevion. M., editors. Frontiers in Aging and Neurodegenerative Disorders: Fundamental Aspects, Clinical Perspectives and New Insights. Amsterdam, The Netherlands:IOS Press. p. 170-181.
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HEAVY PARTICLE IRRADIATION, NEUROCHEMISTRY AND BEHAVIOR: THRESHOLDS, DOSE-RESPONSE CURVES AND RECOVERY OF FUNCTION
- (Peer Reviewed Journal)
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Rabin, B.M., Joseph, J.A., Shukitt Hale, B. 2004. Heavy particle irradiation, neurochemistry and behavior: thresholds, dose-response curves and recovery of function. Advances in Space Research. 33:1330-1333.
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THE EFFECTS OF HEAVY PARTICLE IRRADIATION ON EXPLORATION AND RESPONSE TO ENVIRONMENTAL CHANGE
- (Peer Reviewed Journal)
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Casadesus, G., Shukitt Hale, B., Cantuti-Castelvetri, I., Rabin, B.M., Joseph, J.A. 2004. The effects of heavy particle irradiation on exploration and response to environmental change. Advances in Space Research.
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AGE-RELATED INCREASE IN BRAIN NFK-B IS ATTENUATED BY BLUEBERRY-ENRICHED ANTIOXIDANT DIET
- (Other)
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Goyarzu, P., Lau, F.C., Kaufmann, J., Jennings, R., Taglialatela, G., Shukitt Hale, B., Joseph, J.A., Malin, D. Age-related increase in brain nfk-b is attenuated by blueberry-enriched antioxidant diet. Soc. Neurosci. Abs. 2003, 29, 98.3
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RATS FED A BLUEBERRY-ENRICHED DIET EXHIBIT GREATER PROTECTION AGAINST A KAINATE-INDUCED LEARNING IMPAIRMENT
- (Abstract Only)
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Spangler, E., Duffy, K., Devon, B., Guo, Z., Bowker, J., Shukitt Hale, B., Joseph, J.A., Ingram, D.K. 2003. Rats fed a blueberry-enriched diet exhibit greater protection against a kainate-induced learning impairment. Soc. Neurosci. Abs. 2003, 29, 638.12.
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AGE-RELATED INCREASED IN BRAIN NF-KB IS ATTENUATED BY BLUEBERRY-ENRICHED ANTIOXIDANT DIET
- (Abstract Only)
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Goyarzu, P., Lau, F.C., Kaufmann, J., Jennings, R., Taglialatela, G., Shukitt Hale, B., Joseph, J.A., Malin, D. 2003. Age-related increased in brain nf-kb is attenuated by blueberry-enriched antioxidant diet. Society for Neuroscience Abstracts and Proceedings.
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EFFECTS OF ANTIOXIDANT DIETS ON AGE- AND HEAVY PARTICLE-INDUCED DISRUPTION OF OPERANT RESPONDING IN RATS
- (Abstract Only)
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Rabin, B.M., Jenkins, D.G., Joseph, J.A., Shukitt Hale, B. 2003. Effects of antioxidant diets on age- and heavy particle-induced disruption of operant responding in rats. Society for Neuroscience Abstracts and Proceedings.
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MECHANISMS INVOLVED IN BLUEBERRY ENHANCEMENTS OF MOTOR AND COGNITIVE FUNCTION IN YOUNG AND OLD RATS
- (Abstract Only)
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Shukitt Hale, B., Carey, A.N., Casadesus, G., Galli, R.L., Joseph, J.A. 2003. Mechanisms involved in blueberry enhancements of motor and cognitive function in young and old rats. Soc. Neurosci. Abs. 2003, 29. 633.14
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PHYTOCHEMICALS IN FOODS AND EVERAGES: EFFECTS ON THE CNS
- (Other)
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Shukitt Hale, B., Carey, A.N., Joseph, J.A. Phytochemicals in foods and everages: Effects on the Central Nervous System. In lieberman, H.R., Kanarek, R.B., and Prasad, C.eds. Nutritional Neuroscience. CRC Press, Taylor & Francis Group, LLC Boca Raton, FL, 2005, 393-404.
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BLUEBERRY SUPPLEMENTATION ENHANCES SIGNALING AND PREVENTS BEHAVIORAL DEFICITS IN ALZHEIMER DISEASE MODEL
- (Peer Reviewed Journal)
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Joseph, J.A., Arendash, G., Gordon, M., Diamond, D., Shukitt Hale, B., and Morgan, D. Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model. Nutr. Neurosci. 2003, 6: 153-162.
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EFFECT OF AGE ON THE RADIAL ARM WATER MAZE - A TEST OF SPATIAL LEARNING AND MEMORY
- (Peer Reviewed Journal)
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Shukitt Hale, B., Szprengiel, A., Joseph, J.A. 2004. Effect of age on the radial arm water maze - a test of spatial learning and memory. Neurobiology of Aging. 25(2):223-229.
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COGNITIVE DEFICITS INDUCED BY 56FE RADIATION EXPOSURE
- (Peer Reviewed Journal)
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Shukitt-Hale, B., Casadesus, G., Cantuti-Castelvetri, I., Rabin, B.M., and Joseph, J.A. Cognitive deficits induced by 56Fe radiation exposure. Adv. Space Res. 2003, 31: 119-126.
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LONG-TERM CHANGES IN AMPHETAMINE-INDUCED REINFORCEMENT AND AVERSION IN RATS FOLLOWING EXPOSURE TO 56FE PARTICLES
- (Peer Reviewed Journal)
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Rabin, B.M., Joseph, J.A., and Shukitt-Hale, B. Long-term changes in amphetamine-induced reinforcement and aversion in rats following exposure to 56Fe particles. Adv. Space Res. 2003, 31: 127-133.
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BRAIN SIGNALING AND BEHAVIORAL RESPONSES INDUCED BY EXPOSURE TO 56FE RADIATION
- (Peer Reviewed Journal)
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DENISOVA, N.A., SHUKITT HALE, B., RABIN, B., JOSEPH, J.A. BRAIN SIGNALING AND BEHAVIORAL RESPONSES INDUCED BY EXPOSURE TO 56FE RADIATION. RADIATION RESEARCH. 2002.158(6):725-34.
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DOPAMINE NEUROTOXICITY: AGE-DEPENDENT BEHAVIORAL AND HISTOLOGICAL EFFECTS
- (Peer Reviewed Journal)
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Cantuti-Castelvetri, I., Shukitt-Hale, B., and Joseph, J.A. Dopamine neurotoxicity: Age-dependent behavioral and histological effects. Neurobio. Aging 2003, 24: 697-706.
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INTERACTION BETWEEN HEAVY PARTICLES IRRADIATION AND AGE IN THE DISRUPTION OF FIXED-RATION OPERANT RESPONDING IN RATS
- (Other)
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Rabin, B.M., Shukitt-Hale, B., Joseph, J.A., Buhler, L.L., Jenkins, D.G., and Eggleston, A.M. Interaction between heavy particle irradiation and age in the disruption of fixed - ratio operant responding in rats. Soc. Neurosci. Abs. 2002, 28, 889.11.
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POLYPHENOLICS CAN LOCALIZE WITHIN THE BRAINS OF AGED RATS FED A BLUEBERRY-SUPPLEMENTED DIET
- (Abstract Only)
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Shukitt-Hale, B., Andres-Lacueva, C., Galli, R.L., Jauregui, O., Lamuela-Raventos, R.M., and Joseph, J.A. Polyphenolics can localize within the brains of aged rats fed a blueberry - supplemented diet. Soc. Neurosci. Abs. 2002, 28, 294.6.
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MODULATION OF HIPPOCAMPAL NEUROGENESIS AND COGNITIVE PERFORMANCE IN THE AGED RAT: THE BLUEBERRY EFFECT
- (Other)
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Casadesus, G., Stellwagen, H., Szprengiel, A., Galli, R.L., Smith, M.A., Shukitt Hale, B., Joseph, J.A. 2002. Modulation of hippocampal neurogenesis and cognitive performance in the aged rat: the blueberry effect. Society for Neuroscience Abstracts and Proceedings.
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DIETARY SUPPLEMENTATION WITH FRUIT POLYPHENOLICS AMELIORATES AGE-RELATED DEFICITS IN BEHAVIOR AND NEURONAL MARKERS OF INFLAMMATION AND OXIDATIVE STRESS
- (Other)
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Galli, R.L., Shukitt Hale, B., Bielinski, D.F., Andres-Lacueva, C., Joseph, J.A. 2002. Dietary supplementation with fruit polyphenolics ameliorates age-related deficits in behavior and neuronal markers of inflammation and oxidative stress. Society for Neuroscience Abstracts and Proceedings.
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DIETARY SUPPLEMENTATION WITH BLUEBERRY EXTRACTS IMPROVES THE SURVIVAL AND FUNCTION OF GRAFTED EMBRYONIC DOPAMINE NEURONS IN RATS
- (Other)
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Mcguire, S.O., Shukitt Hale, B., Joseph, J.A., Sortwell, C.E., Fleming, M.F., Marchionini, D.M., Kanaan, N.M., Daley, B., Collier, T.J. 2002. Dietary supplementation with blueberry extracts improves the survival and function of grafted embryonic dopamine neurons in rats. Society for Neuroscience Abstracts and Proceedings.
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EFFECTS OF HEAVY PARTICLES IRRADIATION AND DIET ON AMPHETAMINE- AND LITHIUM CHLORIDE-INDUCED TASTE AVOIDANCE LEARNING IN RATS
- (Peer Reviewed Journal)
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RABIN, B.M., SHUKITT HALE, B., SZPRENGIEL, A., JOSEPH, J.A. EFFECTS OF HEAVY PARTICLES IRRADIATION AND DIET ON AMPHETAMINE- AND LITHIUM CHLORIDE-INDUCED TASTE AVOIDANCE LEARNING IN RATS. BRAIN RESEARCH.853:31-6.
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PRACTICING CALORIC RESTRICTION OR EATING A DIET HIGH IN ANTIOXIDANTS: EQUIVALENT PATHS TO SUCCESSFUL AGING?
- (Peer Reviewed Journal)
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CASADESUS, G., SHUKITT HALE, B., JOSEPH, J.A. PRACTICING CALORIC RESTRICTION OR EATING A DIET HIGH IN ANTIOXIDANTS: EQUIVALENT PATHS TO SUCCESSFUL AGING?. NEUROBIOLOGY OF AGING. 23(5):747-69,2002.
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AGE-RELATED DECLINES IN THE LOCOMOTOR RESPONSE TO ENVIRONMENTAL NOVELTY ANDHOME-CAGE ACTIVITY
- (Peer Reviewed Journal)
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Casadesus, G., Shukitt-Hale, B., and Joseph, J.A. Automated measurement of age-related changes in the locomotor response to environmental novelty and home-cage activity. Mech. Ageing Develop. 2001, 122: 1887 1897.
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EFFECT OF AGE ON OBJECT EXPLORATION, HABITUATION, AND RESPONSE TO SPATIAL AAND NON-SPATIAL CHANGE
- (Peer Reviewed Journal)
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Shukitt-Hale, B., Casadesus, G., Cantuti-Castelvetri, I., and Joseph, J.A. Effect of age on object exploration, habituation, and response to spatial and non-spatial change. Behav. Neurosci. 2001, 115: 1059-1064.
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SHORT-TERM DIETARY SUPPLEMENTATION OF BLUEBERRY POLYPHENOLICS: BENEFICIAL EFFECTS ON AGING BRAIN PERFORMANCE AND PERIPHERAL TISSUE FUNCTION
- (Peer Reviewed Journal)
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Youdim, K.A., Shukitt-Hale, B., Martin, A., Wang, H., Denisova, N., Bickford, P.C., and Joseph, J.A. Short-term dietary supplementation of blueberry polyphenolics: Beneficial effects on aging brain performance and peripheral tissue function. Nutr. Neurosci. 2000, 3: 383-397.
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EFFECTS OF EXPOSURE TO 56FE PARTICLES ON THE ACQUISITION OF A CONDITIONED PLACE PREFERENCE IN RATS
- (Abstract Only)
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Rabin, B. M., Shukitt-Hale, B., Joseph, J. A., and Denisova, N. Effects of exposure to 56Fe particles on the acquisition of a conditioned place preference in rats. Physica Medica 2001, 17 (Suppl. 1): 196-197.
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PSYCHOMOTOR AND SPATIAL MEMORY PERFORMANCE IN AGING MALE FISCHER 344 RATS
- (Peer Reviewed Journal)
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