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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Infectious Bacterial Diseases Research » People & Locations » Paola Boggiatto
Paola Boggiatto
Infectious Bacterial Diseases Research
Veterinary Medical Officer

Phone: (515) 337-6527
Fax:

(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)

Projects
SARS-CoV-2 White-tailed Deer Infection Dynamics and Antibody Persistence
Cooperative Agreement (A)
  Accession Number: 445428
Development of Improved Diagnostic and Control Strategies for Brucellosis in Livestock and Wildlife
In-House Appropriated (D)
  Accession Number: 441161
TB Diagnostics in Vaccinated Cattle and Deer
Interagency Reimbursable Agreement (I)
  Accession Number: 442512
Experimental Infections of Elk With SARS-CoV-2
Interagency Reimbursable Agreement (I)
  Accession Number: 442977
SARS-CoV-2 White-tailed Deer Infection Dynamics and Antibody Persistence
Interagency Reimbursable Agreement (I)
  Accession Number: 443025
Development and Validation of TB Diagnostics for Deer and Cattle that have been Vaccinated with BCG
Interagency Reimbursable Agreement (I)
  Accession Number: 438758
Accelerating Bovine Tuberculosis Control in Developing Countries
Reimbursable Cooperative Agreement (R)
  Accession Number: 445643

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Experimental reproduction of viral replication and disease in dairy calves and lactating cows inoculated with highly pathogenic avian influenza H5N1 clade 2.3.4.4b - (Peer Reviewed Journal)
Pathogen detection in early phases of experimental bovine tuberculosis Reprint Icon - (Peer Reviewed Journal)
Palmer, M.V., Kanipe, C.R., Hwang, S., Thacker, T.C., Lehman, K.A., Ledesma, N.A., Gustafson, K.K., Boggiatto, P.M. 2024. Pathogen detection in early phases of experimental bovine tuberculosis. Veterinary Sciences. https://doi.org/10.3390/vetsci11080357.
Pathogen detection in early phases of experimental bovine tuberculosis Reprint Icon - (Peer Reviewed Journal)
Palmer, M.V., Kanipe, C.R., Hwang, S., Thacker, T.C., Lehman, K.A., Ledesma, N.A., Gustafson, K., Boggiatto, P.M. 2024. Pathogen detection in early phases of experimental bovine tuberculosis. Veterinary Sciences. 11(8). Article 11080357. https://doi.org/10.3390/vetsci11080357.
Characterization of the adaptive cellular and humoral immune responses to persistent colonization of Brucella abortus strain RB51 in a Jersey cow Reprint Icon - (Peer Reviewed Journal)
Boggiatto, P.M., Greiman, H., Falkenberg, S., Sarlo Davila, K.M., Putz, E.J., Olsen, S.C. 2024. Characterization of the adaptive cellular and humoral immune responses to persistent colonization of Brucella abortus strain RB51 in a Jersey cow. Frontiers in Veterinary Science. 11. Article 1367498. https://doi.org/10.3389/fvets.2024.1367498.
An injectable subunit vaccine containing Elongation Factor Tu and Heat Shock Protein 70 protects North American bison from Mycoplasma bovis infection Reprint Icon - (Peer Reviewed Journal)
Kaplan, B.S., Dassanayake, R.P., Briggs, R.E., Kanipe, C.R., Boggiatto, P.M., Crawford, L., Olsen, S.C., Menghwar, H., Casas, E., Tatum, F.M. 2024. An injectable subunit vaccine containing Elongation Factor Tu and Heat Shock Protein 70 protects North American bison from Mycoplasma bovis infection. Frontiers in Veterinary Science. 11. Article 1408861. https://doi.org/10.3389/fvets.2024.1408861.
Persistence of viral RNA in North American elk experimentally infected with an ancestral strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Reprint Icon - (Peer Reviewed Journal)
Boggiatto, P.M., Buckley, A.C., Cassmann, E.D., Seger, H., Olsen, S.C., Palmer, M.V. 2024. Persistence of viral RNA in North American elk experimentally infected with an ancestral strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Scientific Reports. https://doi.org/10.1038/s41598-024-61414-7.
Fecal and vaginal microbiota of vaccinated and non-vaccinated pregnant elk challenged with Brucella abortus Reprint Icon - (Peer Reviewed Journal)
Tibbs-Cortes, B.W., Rahic-Seggerman, F.M., Schmitz-Esser, S., Boggiatto, P.M., Olsen, S.C., Putz, E.J. 2024. Fecal and vaginal microbiota of vaccinated and non-vaccinated pregnant elk challenged with Brucella abortus. Frontiers in Veterinary Science. 11. https://doi.org/10.3389/fvets.2024.1334858.
Evaluation of the primeflow RNA assay as a method of detection of SARS-CoV-2 single and dual infections Reprint Icon - (Peer Reviewed Journal)
Falkenberg, S.M., Buckley, A.C., Boggiatto, P.M. 2023. Evaluation of the primeflow RNA assay as a method of detection of SARS-CoV-2 single and dual infections. Cytotechnology. https://doi.org/10.1007/s10616-023-00608-9.
Genomic regions associated with pseudorabies virus infection status in naturally infected feral swine (Sus scrofa) Reprint Icon - (Peer Reviewed Journal)
Bowden, C.F., Kiser, J.N., Miller, R.S., Buckley, A.C., Boggiatto, P.M., Giglio, R.M., Brown, V.R., Garrick, D., Neibergs, H.L., Piaggio, A.J., Speidel, S.E., Smyser, T.J. 2023. Genomic regions associated with pseudorabies virus infection status in naturally infected feral swine (Sus scrofa). Frontiers in Genetics. https://doi.org/10.3389/fgene.2023.1292671.
Effect of selection genotype on immune response to Brucella abortus RB51 in holstein cattle Reprint Icon - (Peer Reviewed Journal)
Sarlo Davila, K.M., Boggiatto, P.M., Olsen, S.C., Lippolis, J.D., Crooker, B., Putz, E.J. 2023. Effect of selection genotype on immune response to Brucella abortus RB51 in holstein cattle. Animal Genetics. 55(1):47-54. https://doi.org/10.1111/age.13372.
Vaccination of white-tailed deer with Mycobacterium bovis bacillus calmette-guérin (BCG): effect of Mycobacterium avium ssp. paratuberculosis infection Reprint Icon - (Peer Reviewed Journal)
Palmer, M.V., Kanipe, C.R., Lehman, K.A., Thacker, T.C., Putz, E.J., Boggiatto, P.M. 2023. Vaccination of white-tailed deer with Mycobacterium bovis bacillus calmette-guérin (BCG): effect of Mycobacterium avium ssp. paratuberculosis infection. Microorganisms. https://doi.org/10.3390/microorganisms11102488.
Wildlife immune responses to Mycobacterium bovis and to bacille of calmette-guerin Reprint Icon - (Review Article)
Boggiatto, P.M., Kanipe, C.R., Putz, E.J., Olsen, S.C., Palmer, M.V. 2023. Wildlife immune responses to Mycobacterium bovis and to bacille of calmette-guerin. Journal of Immunology. https://doi.org/10.4049/jimmunol.2300323.
Response to bovine viral diarrhea virus in heifers vaccinated with a combination of multivalent modified live and inactivated viral vaccines Reprint Icon - (Peer Reviewed Journal)
Falkenberg, S.M., Dassanayake, R.P., Crawford, L., Sarlo Davila, K.M., Boggiatto, P.M. 2023. Response to bovine viral diarrhea virus in heifers vaccinated with a combination of multivalent modified live and inactivated viral vaccines. Viruses. 15(3). Article 703.. https://doi.org/10.3390/v15030703.
Effects of concurrent administration of modified live viral vaccines with RB51 on immune responses to RB51 Reprint Icon - (Peer Reviewed Journal)
Crawford, L., Falkenberg, S., Putz, E.J., Olsen, S.C., Boggiatto, P.M. 2023. Effects of concurrent administration of modified live viral vaccines with RB51 on immune responses to RB51. Frontiers in Veterinary Science. 10. eArticle 1105485. https://doi.org/10.3389/fvets.2023.1105485.
Histopathologic differences in granulomas of BCG vaccinated and non-vaccinated cattle with bovine tuberculosis Reprint Icon - (Peer Reviewed Journal)
Kanipe, C.R., Boggiatto, P.M., Putz, E.J., Palmer, M.V. 2022. Histopathologic differences in granulomas of BCG vaccinated and non-vaccinated cattle with bovine tuberculosis. Frontiers in Microbiology. 13, Article 1048648. https://doi.org/10.3389/fmicb.2022.1048648.
Pulmonary hamartoma in an elk calf (Cervus elaphus canadensis) Reprint Icon - (Peer Reviewed Journal)
Boggiatto, P.M., Olsen, S.C., Palmer, M.V. 2022. Pulmonary hamartoma in an elk calf (Cervus elaphus canadensis). Journal of Veterinary Diagnostic Investigation. 35(2). https://doi.org/10.1177/10406387221141091.
SARS-CoV-2: Experimental studies on deer-to-deer transmission Reprint Icon - (Abstract Only)
Palmer, M.V., Martins, M., Falkenberg, S.M., Devries, A.C., Caserta, L., Mitchell, P.K., Wagner, B., Cassmann, E.D., Lager, K.M., Diel, D.G., Boggiatto, P.M., Kanipe, C.R., Fernandes, M. 2022. SARS-CoV-2: Experimental studies on deer-to-deer transmission. United States Animal Health Association Proceedings. [Abstract}. https://doi.org/10.1371/journal.ppat.1010197.
Characterization of the duration of immunity of Brucella abortus strain RB51 vaccination in cattle after experimental challenge Reprint Icon - (Peer Reviewed Journal)
Olsen, S.C., Boggiatto, P.M. 2022. Characterization of the duration of immunity of Brucella abortus strain RB51 vaccination in cattle after experimental challenge. Preventive Veterinary Medicine. 206. Article 105705. https://doi.org/10.1016/j.prevetmed.2022.105705.
From Deer-to-Deer: SARS-CoV-2 is efficiently transmitted and presents broad tissue tropism and replication sites in white-tailed deer Reprint Icon - (Peer Reviewed Journal)
Martins, M., Boggiatto, P.M., Buckley, A., Cassmann, E.D., Falkenberg, S.M., Caserta, L.C., Fernandes, M.H., Kanipe, C.R., Lager, K.M., Palmer, M.V., Diel, D.G. 2022. From Deer-to-Deer: SARS-CoV-2 is efficiently transmitted and presents broad tissue tropism and replication sites in highly susceptible white-tailed deer. PLoS Pathogens. 18(3). Article e1010197. https://doi.org/10.1371/journal.ppat.1010197.
Bovine tuberculosis: a disease at the interface of cattle, wildlife and humans Reprint Icon - (Book / Chapter)
Palmer, M.V., Boggiatto, P.M., Kanipe, C., Lombard, J. 2023. Bovine tuberculosis: a disease at the interface of cattle, wildlife and humans. Book Chapter. 11(p 829-846). https://doi.org/10.1007/978-3-031-15955-8.
Brucella - (Book / Chapter)
S.C. Olsen and P. Boggiatto. 2022. Brucella. In: McVey, D.S., Kennedy, M., Chengappa, M.M., and Wilkes, R. Veterinary Microbiology, 4th Edition. Hoboken, NJ: John Wiley & Sons, Inc. p. 151-161.
The bovine tuberculoid granuloma Reprint Icon - (Review Article)
Palmer, M.V., Kanipe, C.R., Boggiatto, P.M. 2022. The bovine tuberculoid granuloma. Pathogens. 11(1). Article 61. https://doi.org/10.3390/pathogens11010061.
Research on a TB vaccine for use in free-ranging white-tailed deer - (Abstract Only)
Immune responses and efficacy of Brucella abortus strain RB51 in bison after delivery in a dry dart formulation or by parenteral inoculation Reprint Icon - (Peer Reviewed Journal)
Olsen, S.C., Boggiatto, P.M., Nol, P., Mccollum, M., Rhyan, J. 2021. Immune responses and efficacy of Brucella abortus strain RB51 in bison after delivery in a dry dart formulation or by parenteral inoculation. Frontiers in Veterinary Science. 8. Article 706160. https://doi.org/10.3389/fvets.2021.706160.
Immune responses and efficacy of Brucella abortus strain RB51 in bison after delivery in a dry dart formulation or by parenteral inoculation Reprint Icon - (Peer Reviewed Journal)
Olsen, S.C., Boggiatto, P.M., Nol, P., Mccollum, M., Rhyan, J. 2021. Immune responses and efficacy of Brucella abortus strain RB51 in bison after delivery in a dry dart formulation or by parenteral inoculation. Frontiers in Veterinary Science. https://doi.org/10.3389/fvets.2021.706160.
Enhanced detection of Mycobacterium bovis-specific T cells in experimentally-infected cattle Reprint Icon - (Peer Reviewed Journal)
Boggiatto, P.M., Kanipe, C.R., Palmer, M.V. 2021. Enhanced detection of Mycobacterium bovis-specific T cells in experimentally-infected cattle. Frontiers in Veterinary Science. https://doi.org/10.3389/fvets.2021.676710.
Mucosal IFN-¿ production and potential role in protection in Escherichia coli O157:H7 vaccinated and challenged cattle Reprint Icon - (Peer Reviewed Journal)
Schaut, R.G., Palmer, M.V., Boggiatto, P.M., Kudva, I.T., Loving, C.L., Sharma, V.K. 2021. Mucosal IFN-¿ production and potential role in protection in Escherichia coli O157:H7 vaccinated and challenged cattle. Infection and Immunity. 11. Article 9769. https://doi.org/10.1038/s41598-021-89113-7.
Heterogeneity of pulmonary granulomas in cattle experimentally infected with Mycobacterium bovis Reprint Icon - (Peer Reviewed Journal)
Palmer, M.V., Thacker, T.C., Kanipe, C.R., Boggiatto, P.M. 2021. Heterogeneity of pulmonary granulomas in cattle experimentally infected with Mycobacterium bovis. Frontiers in Veterinary Science. 8. https://doi.org/10.3389/fvets.2021.671460.
A pseudomolecule assembly of the Rocky Mountain elk genome Reprint Icon - (Peer Reviewed Journal)
Masonbrink, R.E., Alt, D.P., Bayles, D.O., Boggiatto, P.M., Edwards, H., Tatum, F.M., Williams, J.E., Wilson-Welder, J.H., Wood, M., Zimin, A., Severin, A., Olsen, S.C. 2021. A pseudomolecule assembly of the Rocky Mountain elk genome. PLoS ONE. 16(4). https://doi.org/10.1371/journal.pone.0249899.
Quantification of Brucella abortus population structure in a natural host Reprint Icon - (Peer Reviewed Journal)
Fiebig, A., Vrentas, C.E., Le,T, Huebner, M., Boggiatto, P.M., Olsen, S.C., Crosson, S. 2021. Quantification of Brucella abortus population structure in a natural host. Proceedings of the National Academy of Sciences(PNAS). 118. https://doi.org/10.1073/pnas.2023500118.
Applications of nanovaccines for disease prevention in cattle Reprint Icon - (Review Article)
Maina, T.W., Grego, E.A., Boggiatto, P.M., Sacco, R.E., Narasimhan, B., Mcgill, J.L. 2020. Applications of nanovaccines for disease prevention in cattle. Frontiers in Bioengineering and Biotechnology. 8. Article 608050. https://doi.org/10.3389/fbioe.2020.608050.
Loci Associated With Antibody Response in Feral Swine (Sus scrofa)Infected With Brucella suis Reprint Icon - (Peer Reviewed Journal)
Pierce, .F., Brown, V.R., Olsen, S.C., Boggiatto, P.M., Pedersen, K., Miller, R.S. Speidel, S.E., Smyser, T.J. 2020. Loci associated with antibody response in feral swine (Sus scrofa)infected with Brucella suis. Frontiers in Veterinary Science. 7. https://doi.org/10.3389/fvets.2020.554674.
Severity of bovine tuberculosis is associated with innate immune-biased transcriptional signatures of whole blood in early weeks after experimental Mycobacterium bovis infection Reprint Icon - (Peer Reviewed Journal)
Wiarda, J.E., Boggiatto, P.M., Bayles, D.O., Waters, R.W., Thacker, T.C., Palmer, M.V. 2020. Severity of bovine tuberculosis is associated with innate immune-biased transcriptional signatures of whole blood in early weeks after experimental Mycobacterium bovis infection. PLoS ONE. 15(11). https://doi.org/10.1371/journal.pone.0239938.
Influence of species of negative control sera on results of a brucellosis fluorescence polarization assay Reprint Icon - (Peer Reviewed Journal)
Olsen, S.C., Crawford, L., Fuentes, A., Kostovic, M., Boggiatto, P.M. 2020. Influence of species of negative control sera on results of a brucellosis fluorescence polarization assay . Journal of Veterinary Diagnostic Investigation. 33:67-72. https://doi.org/10.1177/1040638720970888.
Enhancing the detection of Brucella-specific CD4+ T cell responses in cattle via in vitro antigenic expansion and restimulation Reprint Icon - (Peer Reviewed Journal)
Boggiatto, P.M., Schaut, R.G., Olsen, S.C. 2020. Enhancing the detection of Brucella-specific CD4+ T cell responses in cattle via in vitro antigenic expansion and restimulation. Frontiers in Immunology. 11:1944. https://doi.org/10.3389/fimmu.2020.01944.
Case report: fading elk syndrome in a herd of captive elk (Cervus elaphus) in the North American midwest Reprint Icon - (Peer Reviewed Journal)
Boggiatto, P.M., Crawford, L.S., Kanipe, C., Palmer, M.V., Olsen, S.C. 2020. Case report: fading elk syndrome in a herd of captive elk (Cervus elaphus) in the North American midwest. Frontiers in Veterinary Science. 7:497. https://doi.org/10.3389/fvets.2020.00497.
Case report: fading elk syndrome in a herd of captive elk (Cervus elaphus) in the North American midwest Reprint Icon - (Peer Reviewed Journal)
Boggiatto, P.M., Crawford, L.S., Kanipe, C., Palmer, M.V., Olsen, S.C. 2020. Case report: fading elk syndrome in a herd of captive elk (Cervus elaphus) in the North American midwest. Meeting Abstract. 7. https://doi.org/10.3389/fvets.2020.00497.
Immune responses and clinical effects of experimental challenge of elk with Brucella abortus strain 2308 Reprint Icon - (Peer Reviewed Journal)
Olsen, S.C., Boggiatto, P.M., Kanipe, C. 2020. Immune responses and clinical effects of experimental challenge of elk with Brucella abortus strain 2308. Veterinary Immunology and Immunopathology. 227. https://doi.org/10.1016/j.vetimm.2020.110086.
Bovine immune response to leptospiral antigen in different novel adjuvants and vaccine delivery platforms Reprint Icon - (Peer Reviewed Journal)
Wilson-Welder, J.H., Boggiatto, P.M., Nally, J.E., Wafa, E.I., Alt, D.P., Hornsby, R.L., Frank, A.T., Jones, D.E., Olsen, S.C., Bowden, N.B., Salem, A.K. 2020. Bovine immune response to leptospiral antigen in different novel adjuvants and vaccine delivery platforms. Vaccine. 38(18):3464-3473. https://doi.org/10.1016/j.vaccine.2020.02.086.
Tulathromycin treatment does not affect bacterial dissemination or clearance of Brucella melitensis 16M following experimental infection of goats Reprint Icon - (Peer Reviewed Journal)
Boggiatto, P.M., Olsen, S.C. 2019. Tulathromycin treatment does not affect bacterial dissemination or clearance of Brucella melitensis 16M following experimental infection of goats. PLoS One. 14(12):e0226242. https://doi.org/10.1371/journal.pone.0226242.
Characterization of the NLRP1 inflammasome response in bovine species Reprint Icon - (Peer Reviewed Journal)
Vrentas, C.E., Boggiatto, P.M., Olsen, S.C., Leppla, S.H., Moayeri, M. 2020. Characterization of the NLRP1 inflammasome response in bovine species. Innate Immunity. 26(4):301-311. https://doi.org/10.1177/1753425919886649.
Sustained antigen release, polyanhydride-based vaccine platform for immunixation against bovine brucellosis Reprint Icon - (Peer Reviewed Journal)
Boggiatto, P.M., Schaut, R.G., Kanipe, C., Kelly, S.M., Narasimhan, B., Jones, D.E., Olsen, S.C. 2019. Sustained antigen release, polyanhydride-based vaccine platform for immunixation against bovine brucellosis. Heliyon. 5(8). https://doi.org/10.1016/j.heliyon.2019.e02370.
Cellular and mucosal immune responses following vaccination with inactivated mutant of Escherichia coli O157:H7 Reprint Icon - (Peer Reviewed Journal)
Schaut, R.G., Boggiatto, P.M., Loving, C.L., Sharma, V.K. 2019. Cellular and mucosal immune responses following vaccination with inactivated mutant of Escherichia coli O157:H7. Scientific Reports. 9:6401. https://doi.org/10.1038/s41598-019-42861-z.
Coincidence cloning recovery of Brucella melitensis RNA from goat tissues: advancing the in vivo analysis of pathogen gene expression in brucellosis Reprint Icon - (Peer Reviewed Journal)
Boggiatto, P.M., Vrentas, C.E., Fitzsimmons, D.J., Bayles, D.O., Alt, D.P., Olsen, S.C. 2018. Coincidence cloning recovery of Brucella melitensis RNA from goat tissues: advancing the in vivo analysis of pathogen gene expression in brucellosis. BioMed Central (BMC) Molecular Biology. 19:10. https://doi.org/10.1186/s12867-018-0111-x.
Inflammasomes in livestock and wildlife: Insights into the intersection of pathogens and natural host species Reprint Icon - (Review Article)
Vrentas, C.E., Schaut, R.G., Boggiatto, P.M., Olsen, S.C., Sutterwala, F.G., Moayeri, M. 2018. Inflammasomes in livestock and wildlife: Insights into the intersection of pathogens and natural host species. Veterinary Immunology and Immunopathology. 201:49-56. https://doi.org/10.1016/j.vetimm.2018.05.008.
Collection and processing of lymph nodes from large animals for RNA analysis: preparing for lymph node transcriptomic studies of large animal species Reprint Icon - (Peer Reviewed Journal)
Vrentas, C.E., Boggiatto, P.M., Schaut, R.G., Olsen, S.C. 2018. Collection and processing of lymph nodes from large animals for RNA analysis: preparing for lymph node transcriptomic studies of large animal species. Journal of Visualized Experiments. 135:e57195. doi:10.3791/57195.
Biosafety concerns related to Brucella and its potential use as a bioweapon Reprint Icon - (Peer Reviewed Journal)
Olsen, S.C., Boggiatto, P.M., White, D.M., McNunn, T.B. 2018. Biosafety concerns related to Brucella and its potential use as a bioweapon. Applied Biosafety. 23(2)77-90. https://doi.org/10.1177/1535676018771983.
Inactivation of virulent Brucella species in culture and animal samples Reprint Icon - (Peer Reviewed Journal)
Olsen, S.C., Boggiatto, P.M., Vrentas, C.E. 2017. Inactivation of virulent Brucella species in culture and animal samples. Applied Biosafety. 22(4):145-151. https://doi.org/10.1177/1535676017734202.
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