Kristen Byrne
Food Safety and Enteric Pathogens Research
Research Biologist
Phone: (515) 337-6663
Fax:
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Publications
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Commercially available anti-human/-mouse monoclonal antibodies cross-reactive to agriculture and wildlife species
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Characterizing expression profiles of turkey immune cell populations within peripheral blood using single-cell transcriptomics
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Identification of anti-human and mouse mAb cross-reactive to agriculture and wildlife species
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Altered cytokine production and gene expression by porcine monocytes following neonatal inoculation with bacillus Calmette-Guerin
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BCG induced innate training in neonatal and weaned pigs is dependent on route of administration
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Integrative profiling of gene expression and chromatin accessibility elucidates specific transcriptional networks in porcine neutrophils
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Herrera Uribe, J., Lim, K., Byrne, K.A., Daharsh, L., Liu, H., Corbett, R.J., Marco, G., Schroyen, M., Koltes, J.E., Loving, C.L., Tuggle, C.K. 2023. Integrative profiling of gene expression and chromatin accessibility elucidates specific transcriptional networks in porcine neutrophils. Frontiers in Genetics. 14. Article 1107462. https://doi.org/10.3389/fgene.2023.1107462.
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Short transportation did not impact circulating cortisol levels or leukocyte abundance in cattle
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Alternatives to Antibiotics: neonatal immunomodulation to improve disease resistance in animals
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Annotating cell transcriptomes in four immune tissues to establish a porcine single-cell Immune Atlas
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Improving blood phenomics: ISU station report
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Integrative profiling of gene expression and chromatin accessibility elucidates specific transcriptional networks in porcine neutrophils
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Characterization and applications of advanced regulatory element annotation in circulating porcine immune cells
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Definition of regulatory elements and transcription factors controlling immune cell gene expression at single cell resolution using single cell ATAC-Seq
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3’mRNA-Seq analysis of the effects of weaning and influenza infection on gene expression in whole blood of pigs
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Evaluation of digestively resistant or soluble fibers, short- and medium-chain fatty acids, trace minerals, and antibiotics in nonchallenged nursery pigs on performance, digestibility, and intestinal integrity
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Kerr, B.J., Trachsel, J.M., Bearson, B.L., Loving, C.L., Bearson, S.M., Byrne, K.A., Pearce, S.C., Ramirez, S.M., Gabler, N.K., Schweer, W.P., Helm, E.T., De Mille, C.M. 2022. Evaluation of digestively resistant or soluble fibers, short- and medium-chain fatty acids, trace minerals, and antibiotics in nonchallenged nursery pigs on performance, digestibility, and intestinal integrity. Journal of Animal Science. 100(11). Article skac282. https://doi.org/10.1093/jas/skac282.
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Diversity of Alternative Splicing in Porcine Peripheral Blood Immune Cells
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Integration of epigenomic and transcriptomic data to identify regulatory elements and networks controlling immune cell-type gene expression in the pig
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Short chain fatty acids and bacterial taxa associated with reduced Salmonella enterica serovar I 4,[5],12:i:- Shedding in swine fed a diet supplemented with resistant potato starch
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Trachsel, J.M., Bearson, B.L., Kerr, B.J., Shippy, D.C., Byrne, K.A., Loving, C.L., Bearson, S.M. 2022. Short chain fatty acids and bacterial taxa associated with reduced Salmonella enterica serovar I 4,[5],12:i:- Shedding in swine fed a diet supplemented with resistant potato starch. Microbiology Spectrum. 10(3). Article e0220221. https://doi.org/10.1128/spectrum.02202-21.
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Intravenous BCG induction of innate memory in young pigs
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Integrative Profiling of Gene Expression and Chromatin Accessibility Elucidates Specific Transcriptional Networks in Porcine Neutrophils
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Converse trends with adaptive and innate immune responses following intravenous BCG inoculation in pigs
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Reference transcriptomes of porcine peripheral immune cells created through bulk and single-cell RNA sequencing
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Herrera-Uribe, J., Wiarda, J., Sivasankaran, S.K., Daharsh, L., Liu, H., Byrne, K.A., Smith, T.P., Lunney, J.K., Loving, C.L., Tuggle, C.K. 2021. Reference transcriptomes of porcine peripheral immune cells created through bulk and single-cell RNA sequencing. Frontiers in Genetics. 12. Article 689406. https://doi.org/10.3389/fgene.2021.689406.
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Butyrate alters lipopolysaccharide-induced inflammatory response by porcine monocytes
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Integrative profiling of chromatin accessibility and gene expression elucidate specific transcriptional network in porcine neutrophils
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Characterization of circulating porcine immune cells using single-cell RNA-sequencing and comparison to human datasets
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Single cell and deep transcriptomic analysis identify common and cell type specific genes in porcine immune cell
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Differential induction of innate memory in porcine monocytes by B-glucan or bacillus Calmette-Guerin
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Byrne, K.A., Tuggle, C., Loving, C.L. 2020. Differential induction of innate memory in porcine monocytes by B-glucan or bacillus Calmette-Guerin. Innate Immunity. https://doi.org/10.1177/1753425920951607.
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Changes in H3K27ac at gene regulatory regions in porcine alveolar macrophages following LPS or PolyIC exposure
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Uribe, J.H., Liu, H., Byrne, K.A., Bond, Z.F., Loving, C.L., Tuggle, C. 2020. Changes in H3K27ac at gene regulatory regions in porcine alveolar macrophages following LPS or PolyIC exposure. Frontiers in Genetics. 11. https://doi.org/10.3389/fgene.2020.00817.
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Intraepithelial T cells diverge by intestinal location as pigs age
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Wiarda, J.E., Trachsel, J.M., Bond, Z.F., Byrne, K.A., Gabler, N.K., Loving, C.L. 2020. Intraepithelial T cells diverge by intestinal location as pigs age. Frontiers in Immunology. 11:1139. https://doi.org/10.3389/fimmu.2020.01139.
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Innate immunomodulation in food animals: evidence for trained immunity?
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Byrne, K.A., Loving, C.L., McGill, J.L. 2020. Innate immunomodulation in food animals: evidence for trained immunity? Frontiers in Immunology. 11:1099. https://doi.org/10.3389/fimmu.2020.01099.
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Novel engraftment and T cell differentiation of human hematopoietic cells in Art-/- IL2RG-/SCID pigs
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Boettcher, A.N., Li, Y., Ahrens, A.P., Kiupel, M., Byrne, K.A., Loving, C.L., Cino-Ozuna, A., Wiarda, J.E., Adur, M., Schultz, B., Swanson, J.J., Snella, E.M., Ho, C., Charley, S.E., Kiefer, Z.E., Cunnick, J.E., Putz, E.J., Giuseppe, Dell A., Jens, J., Sathe, S., Goldman, F., Westin, E.R., Dekkers, J.C.M., Ross, J.W., Tuggle, C.K. 2020. Novel engraftment and T cell differentiation of human hematopoietic cells in Art-I- IL2RG-IY SCID pigs. Frontiers in Immunology. 11:100. https://doi.org/10.3389/fimmu.2020.00100.
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